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The map label for this gene is serB [C]

Identifier: 110634095

GI number: 110634095

Start: 1864226

End: 1865113

Strand: Direct

Name: serB [C]

Synonym: Meso_1744

Alternate gene names: 110634095

Gene position: 1864226-1865113 (Clockwise)

Preceding gene: 110634092

Following gene: 110634096

Centisome position: 42.25

GC content: 61.6

Gene sequence:

>888_bases
ATGGCCCTCGTCGCAACGCTCATCTCCAACCCGCGGTCACCAGCCGTGAGCCTGCCCCTGGCGAATATGGCGAGCCGCGC
TGTCGGTGCAAGCGAAGTCAGATGGCTGGATGAATCCATCGCCTGCGATCTAATGCTTCCCGACGACGCCAGACAGGAAG
AAGCAGAAGCAATCCTGCGCGAGGCCGTGGCCGGCACCCCAGTGGATGTCGCGGTACAGCCATCTCAGGCTCGCCGCAAG
AAAATGCTCATCGCCGACATGGATTCCACCATGATCGATCAGGAATGCATCGATGAGCTGGCCGACGAAATAGGCATCAA
GGATCATGTGGCGGCCATCACAGCGCGCGCGATGAACGGGGAAATCGCATTCGAGCCGGCCCTGCGCGAGCGCGTGGCGC
TTCTTGAAGGCCTTCAGCTGGAAGTCATCGAGCAGGTGATCACCGGCCGGATAACACTGGCCGCAGGCGGTCGCGAACTG
ATCGCCACCATGCGCAATGCCGGTGCTTATACGGCGCTCGTTTCAGGCGGTTTCGACATTTTCACCGGCCGGATCGCGGC
TCTGCTCGGCTTCCACGAGCACCGGGCCAACCAGCTTGTCATTCAAAGCGGCAAACTGGCGGGAACGGTGGTGGAACCGA
TCCTGGGCAGACAGGCGAAGGCTGCTGCCCTCCTGGAGATTGCCGCCCGCCTCGAACTGGATTTAAGCGAGGTGATGGCT
GTGGGCGACGGCGCCAACGATCTCGATATGCTGAGGCTTGCGGGGACCGGCGTGGCAATCCACGCGAAACCCGCCGTCGC
AGCCGAGGTGCATATCCGCATCGACCATGGCGATCTTACCGCGCTTCTCTATCTCCAGGGATATAGCCGCAACGATTTTG
CGCGATGA

Upstream 100 bases:

>100_bases
CGCCATTTGAAGCGCCAGCGCCGACTTGCCGCTGGCCGTAGGCCCGGCTATCAGGGTGGCGCCTTTCAACATCGGTTTTC
CACTTTCGGCGGATTCTTTC

Downstream 100 bases:

>100_bases
ACCCGATCACCACCGACCGTCTCATCCTGCGCAATTGGGAGGAGCGCGACCGCGGCCTTTTTCATCGCATCAATTGCGAT
GAAAAGGTGATGGAGTTCTT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MALVATLISNPRSPAVSLPLANMASRAVGASEVRWLDESIACDLMLPDDARQEEAEAILREAVAGTPVDVAVQPSQARRK
KMLIADMDSTMIDQECIDELADEIGIKDHVAAITARAMNGEIAFEPALRERVALLEGLQLEVIEQVITGRITLAAGGREL
IATMRNAGAYTALVSGGFDIFTGRIAALLGFHEHRANQLVIQSGKLAGTVVEPILGRQAKAAALLEIAARLELDLSEVMA
VGDGANDLDMLRLAGTGVAIHAKPAVAAEVHIRIDHGDLTALLYLQGYSRNDFAR

Sequences:

>Translated_295_residues
MALVATLISNPRSPAVSLPLANMASRAVGASEVRWLDESIACDLMLPDDARQEEAEAILREAVAGTPVDVAVQPSQARRK
KMLIADMDSTMIDQECIDELADEIGIKDHVAAITARAMNGEIAFEPALRERVALLEGLQLEVIEQVITGRITLAAGGREL
IATMRNAGAYTALVSGGFDIFTGRIAALLGFHEHRANQLVIQSGKLAGTVVEPILGRQAKAAALLEIAARLELDLSEVMA
VGDGANDLDMLRLAGTGVAIHAKPAVAAEVHIRIDHGDLTALLYLQGYSRNDFAR
>Mature_294_residues
ALVATLISNPRSPAVSLPLANMASRAVGASEVRWLDESIACDLMLPDDARQEEAEAILREAVAGTPVDVAVQPSQARRKK
MLIADMDSTMIDQECIDELADEIGIKDHVAAITARAMNGEIAFEPALRERVALLEGLQLEVIEQVITGRITLAAGGRELI
ATMRNAGAYTALVSGGFDIFTGRIAALLGFHEHRANQLVIQSGKLAGTVVEPILGRQAKAAALLEIAARLELDLSEVMAV
GDGANDLDMLRLAGTGVAIHAKPAVAAEVHIRIDHGDLTALLYLQGYSRNDFAR

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=170, Percent_Identity=32.3529411764706, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1790849, Length=214, Percent_Identity=39.2523364485981, Blast_Score=144, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI115534454, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534456, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=185, Percent_Identity=31.8918918918919, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321647, Length=228, Percent_Identity=36.8421052631579, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24661601, Length=202, Percent_Identity=26.7326732673267, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31401; Mature: 31269

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVATLISNPRSPAVSLPLANMASRAVGASEVRWLDESIACDLMLPDDARQEEAEAILR
CCEEEEHHCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHH
EAVAGTPVDVAVQPSQARRKKMLIADMDSTMIDQECIDELADEIGIKDHVAAITARAMNG
HHHCCCCEEEEECCHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
EIAFEPALRERVALLEGLQLEVIEQVITGRITLAAGGRELIATMRNAGAYTALVSGGFDI
CEEECHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHH
FTGRIAALLGFHEHRANQLVIQSGKLAGTVVEPILGRQAKAAALLEIAARLELDLSEVMA
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
VGDGANDLDMLRLAGTGVAIHAKPAVAAEVHIRIDHGDLTALLYLQGYSRNDFAR
HCCCCCCHHHHEEECCCEEEEECCCEEEEEEEEEECCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
ALVATLISNPRSPAVSLPLANMASRAVGASEVRWLDESIACDLMLPDDARQEEAEAILR
CEEEEHHCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHH
EAVAGTPVDVAVQPSQARRKKMLIADMDSTMIDQECIDELADEIGIKDHVAAITARAMNG
HHHCCCCEEEEECCHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
EIAFEPALRERVALLEGLQLEVIEQVITGRITLAAGGRELIATMRNAGAYTALVSGGFDI
CEEECHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHH
FTGRIAALLGFHEHRANQLVIQSGKLAGTVVEPILGRQAKAAALLEIAARLELDLSEVMA
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
VGDGANDLDMLRLAGTGVAIHAKPAVAAEVHIRIDHGDLTALLYLQGYSRNDFAR
HCCCCCCHHHHEEECCCEEEEECCCEEEEEEEEEECCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]