Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 110633989

GI number: 110633989

Start: 1763640

End: 1765526

Strand: Direct

Name: ppiD [H]

Synonym: Meso_1637

Alternate gene names: 110633989

Gene position: 1763640-1765526 (Clockwise)

Preceding gene: 110633974

Following gene: 110633990

Centisome position: 39.97

GC content: 60.15

Gene sequence:

>1887_bases
ATGCTTGATAGTCTTCGAAAAGCGGCAACCACCTGGGTTGCAAAACTCCTGCTCGTAGTTCTTGTCGTGAGTTTTGCGGT
TTGGGGCATTTCCGGTTCGATGCTCACCGGTACCAGCGGCGACGTCATTACCGCCGGTGGCACAAGTGTTTCAGCTCTTG
ACTATCGCCTGGCCTATGATCGGCGCATCGCCGAACTTTCAAGGCAGTTCGGCACTCGCCTGACGCGGGAGCAAGCCGTA
GCCTTCGGCATCGACGAGCAGGTTCTCTCCCAATTGTCCGCGGGGGCGGTGCTGGACGAAACCGCGCGGGAAATCGGCCT
CGGCGTCTCCAAGGATAAGCTCGCCGAGCTTACTGCTTCTGATCCTGCTTTCCGCGGTCTGGACGGAAGATTCGACAGAA
GTCAGTTCGAGTTCGTGCTGAGCCGGATCGGCATGCGGCCTGAGGACTATCTCAAGAACCGCGAACAAGCGGCGGTACGG
CAGCAAATCATCGATGCCGTCGCAAGTGGCGTTTCCGCGCCCGACGAACTGCTGCGCAGTCTTGCGCGTTATCGGGGCGA
GGACCGTACAATTGAATATGTGGCCCTGCCCCGCTCGGCGGTTGAGCCAGTGGAGCCGCCCAGCGACGAACAGCTTCAAA
CTTGGTTTGAGGAGCGCAAGGATAACTACGCCGCGCCCGAGTACCGAAAGATCGAGTATGTGAAGCTTGAAGCTGAAGAC
ATCGCCGACCCGTCGGTGATTTCGGACGAGCAGGTCGAAAGCTATTATCAGCAGAATCAGGCGCAATACACGACGCCTGA
GCGGCGCCAGGTCGAACAATTGACCTTTGCTTCCGCCGAGGAAGCCACGGCCGCGCGCGAGAGCATGCGCACTGGAACCA
CTTTCGAGGACCTGATTGAGCGGCAGGGAAAGAAGCTGCAGGATGTCAGCCTCGGCACATTGACGCGTGCTGACATACCG
GACCAGGTTATCGCCGATGCGGTTTTCTCGCTTACCGAGGATCAGGTGAGCGATGTGGTGCAGGGCACCTTCGGCCCCGT
GCTGCTCCGCGTGACGGAGATCACGCCGGAAGCCGTGACCCCGCTCGACCAGGTTAAAGAAGAAATTCGTCAGCAGCTGG
CGCTGGATGAAGCGAACCGGTTGCTGCTCGACACCTACGACCAGTATGAAGACGCACGTGCCGGAGGCGATACACTGCAG
GAAGCGGCAGAGCGGCTCAGCCTGACCGTAGGCACGATTGATGCGGTCGACAGGGACGGCAACAAACCGGACGGCACGCG
CGTGGAAGATGTCCCCAACCTGCCGGCGCTGCTCGCGGAGGCGTTCCAGACGGAAGTGGGGGTCGAGAATGCTCCCATCA
ACCTGACCGGCAGTGGTTTCCTCTTCTATGAAGTTGCCGAAATCGTGCCCGCGCGCGACCGGGAATTTTCTGAGGTCCGC
GACCGCGTCCTCGAGGATTGGACCGAGGCGGAAGTCACTTCCAGGCTCGACGCCCGTGCAAAGGCGCTGCAGGAAGAGAT
AAAGAACGGCAAGACGCTTGATGAAATCAGCACGGAACTTGGCCAGGAGAAGATGGTCAAGAGAGGCCTGAAGCGTGAAG
CAAGCGACGCAGATCTTGGACAGACCGGCGTGGCAGCCGTCTTCAGTGTGGCGAAGGGAGAAACTGGCACCGTCGCCAAT
CCGGCAGGGGACGCGCGTTTCATTTTCCAGGTGACCGAGGTGTTCGAGCCCGCCTCGGCGACGGCCGAATCCTTGCCGGA
CGACATCAAGACCGCGGTCAATCAGGGCTTGGAAAACGACCTTCTCGACCAGCTCGTGACGCGCCTCCAGGCCGAGCATG
GCGTCACGGTAAATCGCACGGCAATGCAGCAAGCACTCGCCTTCTGA

Upstream 100 bases:

>100_bases
AAGACGCCACAAAGCAATCGACAGCTGTGTTCCAGAGCGCTATTCCCAATTAGAGAAAACGAACAGCAGCCAATTTCCAC
CTACGGACAGCAGAGACCAC

Downstream 100 bases:

>100_bases
CCAATGGCTGATCTCAAGGCACATATCGCCAAAGTGGCTTCCGGAGCTGCGCTGAGCTTTGCCGAAGCGCGTGAAGCTTT
CGGGATCATCATGTCCGGCG

Product: peptidyl-prolyl cis-trans isomerse D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MLDSLRKAATTWVAKLLLVVLVVSFAVWGISGSMLTGTSGDVITAGGTSVSALDYRLAYDRRIAELSRQFGTRLTREQAV
AFGIDEQVLSQLSAGAVLDETAREIGLGVSKDKLAELTASDPAFRGLDGRFDRSQFEFVLSRIGMRPEDYLKNREQAAVR
QQIIDAVASGVSAPDELLRSLARYRGEDRTIEYVALPRSAVEPVEPPSDEQLQTWFEERKDNYAAPEYRKIEYVKLEAED
IADPSVISDEQVESYYQQNQAQYTTPERRQVEQLTFASAEEATAARESMRTGTTFEDLIERQGKKLQDVSLGTLTRADIP
DQVIADAVFSLTEDQVSDVVQGTFGPVLLRVTEITPEAVTPLDQVKEEIRQQLALDEANRLLLDTYDQYEDARAGGDTLQ
EAAERLSLTVGTIDAVDRDGNKPDGTRVEDVPNLPALLAEAFQTEVGVENAPINLTGSGFLFYEVAEIVPARDREFSEVR
DRVLEDWTEAEVTSRLDARAKALQEEIKNGKTLDEISTELGQEKMVKRGLKREASDADLGQTGVAAVFSVAKGETGTVAN
PAGDARFIFQVTEVFEPASATAESLPDDIKTAVNQGLENDLLDQLVTRLQAEHGVTVNRTAMQQALAF

Sequences:

>Translated_628_residues
MLDSLRKAATTWVAKLLLVVLVVSFAVWGISGSMLTGTSGDVITAGGTSVSALDYRLAYDRRIAELSRQFGTRLTREQAV
AFGIDEQVLSQLSAGAVLDETAREIGLGVSKDKLAELTASDPAFRGLDGRFDRSQFEFVLSRIGMRPEDYLKNREQAAVR
QQIIDAVASGVSAPDELLRSLARYRGEDRTIEYVALPRSAVEPVEPPSDEQLQTWFEERKDNYAAPEYRKIEYVKLEAED
IADPSVISDEQVESYYQQNQAQYTTPERRQVEQLTFASAEEATAARESMRTGTTFEDLIERQGKKLQDVSLGTLTRADIP
DQVIADAVFSLTEDQVSDVVQGTFGPVLLRVTEITPEAVTPLDQVKEEIRQQLALDEANRLLLDTYDQYEDARAGGDTLQ
EAAERLSLTVGTIDAVDRDGNKPDGTRVEDVPNLPALLAEAFQTEVGVENAPINLTGSGFLFYEVAEIVPARDREFSEVR
DRVLEDWTEAEVTSRLDARAKALQEEIKNGKTLDEISTELGQEKMVKRGLKREASDADLGQTGVAAVFSVAKGETGTVAN
PAGDARFIFQVTEVFEPASATAESLPDDIKTAVNQGLENDLLDQLVTRLQAEHGVTVNRTAMQQALAF
>Mature_628_residues
MLDSLRKAATTWVAKLLLVVLVVSFAVWGISGSMLTGTSGDVITAGGTSVSALDYRLAYDRRIAELSRQFGTRLTREQAV
AFGIDEQVLSQLSAGAVLDETAREIGLGVSKDKLAELTASDPAFRGLDGRFDRSQFEFVLSRIGMRPEDYLKNREQAAVR
QQIIDAVASGVSAPDELLRSLARYRGEDRTIEYVALPRSAVEPVEPPSDEQLQTWFEERKDNYAAPEYRKIEYVKLEAED
IADPSVISDEQVESYYQQNQAQYTTPERRQVEQLTFASAEEATAARESMRTGTTFEDLIERQGKKLQDVSLGTLTRADIP
DQVIADAVFSLTEDQVSDVVQGTFGPVLLRVTEITPEAVTPLDQVKEEIRQQLALDEANRLLLDTYDQYEDARAGGDTLQ
EAAERLSLTVGTIDAVDRDGNKPDGTRVEDVPNLPALLAEAFQTEVGVENAPINLTGSGFLFYEVAEIVPARDREFSEVR
DRVLEDWTEAEVTSRLDARAKALQEEIKNGKTLDEISTELGQEKMVKRGLKREASDADLGQTGVAAVFSVAKGETGTVAN
PAGDARFIFQVTEVFEPASATAESLPDDIKTAVNQGLENDLLDQLVTRLQAEHGVTVNRTAMQQALAF

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=397, Percent_Identity=26.9521410579345, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69058; Mature: 69058

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSLRKAATTWVAKLLLVVLVVSFAVWGISGSMLTGTSGDVITAGGTSVSALDYRLAYD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCHHHHHHHHHHH
RRIAELSRQFGTRLTREQAVAFGIDEQVLSQLSAGAVLDETAREIGLGVSKDKLAELTAS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCC
DPAFRGLDGRFDRSQFEFVLSRIGMRPEDYLKNREQAAVRQQIIDAVASGVSAPDELLRS
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LARYRGEDRTIEYVALPRSAVEPVEPPSDEQLQTWFEERKDNYAAPEYRKIEYVKLEAED
HHHHCCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHH
IADPSVISDEQVESYYQQNQAQYTTPERRQVEQLTFASAEEATAARESMRTGTTFEDLIE
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RQGKKLQDVSLGTLTRADIPDQVIADAVFSLTEDQVSDVVQGTFGPVLLRVTEITPEAVT
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCC
PLDQVKEEIRQQLALDEANRLLLDTYDQYEDARAGGDTLQEAAERLSLTVGTIDAVDRDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
NKPDGTRVEDVPNLPALLAEAFQTEVGVENAPINLTGSGFLFYEVAEIVPARDREFSEVR
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHH
DRVLEDWTEAEVTSRLDARAKALQEEIKNGKTLDEISTELGQEKMVKRGLKREASDADLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QTGVAAVFSVAKGETGTVANPAGDARFIFQVTEVFEPASATAESLPDDIKTAVNQGLEND
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCHHH
LLDQLVTRLQAEHGVTVNRTAMQQALAF
HHHHHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MLDSLRKAATTWVAKLLLVVLVVSFAVWGISGSMLTGTSGDVITAGGTSVSALDYRLAYD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCHHHHHHHHHHH
RRIAELSRQFGTRLTREQAVAFGIDEQVLSQLSAGAVLDETAREIGLGVSKDKLAELTAS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCC
DPAFRGLDGRFDRSQFEFVLSRIGMRPEDYLKNREQAAVRQQIIDAVASGVSAPDELLRS
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LARYRGEDRTIEYVALPRSAVEPVEPPSDEQLQTWFEERKDNYAAPEYRKIEYVKLEAED
HHHHCCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHH
IADPSVISDEQVESYYQQNQAQYTTPERRQVEQLTFASAEEATAARESMRTGTTFEDLIE
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RQGKKLQDVSLGTLTRADIPDQVIADAVFSLTEDQVSDVVQGTFGPVLLRVTEITPEAVT
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCC
PLDQVKEEIRQQLALDEANRLLLDTYDQYEDARAGGDTLQEAAERLSLTVGTIDAVDRDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
NKPDGTRVEDVPNLPALLAEAFQTEVGVENAPINLTGSGFLFYEVAEIVPARDREFSEVR
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHH
DRVLEDWTEAEVTSRLDARAKALQEEIKNGKTLDEISTELGQEKMVKRGLKREASDADLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QTGVAAVFSVAKGETGTVANPAGDARFIFQVTEVFEPASATAESLPDDIKTAVNQGLEND
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCHHH
LLDQLVTRLQAEHGVTVNRTAMQQALAF
HHHHHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]