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The map label for this gene is hfq

Identifier: 110633965

GI number: 110633965

Start: 1737163

End: 1737411

Strand: Reverse

Name: hfq

Synonym: Meso_1613

Alternate gene names: 110633965

Gene position: 1737411-1737163 (Counterclockwise)

Preceding gene: 110633966

Following gene: 110633964

Centisome position: 39.38

GC content: 52.61

Gene sequence:

>249_bases
ATGGCGGAACGTTCCCAAAATCTGCAGGATTTATTTCTCAACACCGTTCGCAAGAGCAAGAACCCGCTGACGATATTTCT
GATCAACGGCGTGAAATTGACAGGTGTGGTTACATCGTTCGACAATTTCTGTGTTCTTCTGCGCCGGGATGGGCACTCAC
AGCTTGTCTACAAGCATGCGATCTCCACGATCATGCCCAGCCAGCCGGTGCAGCTGTTCGAGGCGGAGGAAGGTAGTCGG
GAAGGCTGA

Upstream 100 bases:

>100_bases
GGCGTTCGGCGCGGGCGCGGCAGGAGGGCAGTTGCCGCGCTTGACGGGCGGGATCAGTTTTGCGCTACTGCCAGCGAAGC
GCAGGGGATGAAAAAAAACA

Downstream 100 bases:

>100_bases
TTGGCAGGAAAACCCAAGGCGCACCATGCGGCGGGAGTCGCCCAGGATGGGGCGGGTGCTTCAGCGCGCACCAAGGCTGT
CGTCGTAGCGCCTAGCGTTG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAERSQNLQDLFLNTVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQLFEAEEGSR
EG

Sequences:

>Translated_82_residues
MAERSQNLQDLFLNTVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQLFEAEEGSR
EG
>Mature_81_residues
AERSQNLQDLFLNTVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQLFEAEEGSRE
G

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=53.7313432835821, Blast_Score=82, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_MESSB (Q11HW7)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674173.1
- ProteinModelPortal:   Q11HW7
- SMR:   Q11HW7
- STRING:   Q11HW7
- GeneID:   4179819
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1613
- NMPDR:   fig|266779.1.peg.359
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- PhylomeDB:   Q11HW7
- ProtClustDB:   PRK00395
- BioCyc:   MSP266779:MESO_1613-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9236; Mature: 9105

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERSQNLQDLFLNTVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPSQPVQLFEAEEGSREG
HHHCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
AERSQNLQDLFLNTVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPSQPVQLFEAEEGSREG
HHHCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA