Click here to switch to the map view.

The map label for this gene is dacC [H]

Identifier: 110633932

GI number: 110633932

Start: 1700668

End: 1701816

Strand: Direct

Name: dacC [H]

Synonym: Meso_1580

Alternate gene names: 110633932

Gene position: 1700668-1701816 (Clockwise)

Preceding gene: 110633931

Following gene: 110633933

Centisome position: 38.54

GC content: 59.53

Gene sequence:

>1149_bases
TTGATTCGACTGGCCTCTGCATTGAGCTTGTTGGTCCTTGCCTTCGTGCCACTCCCTTTCGCGCGTGCCCAAAGCTTTGA
GACGAAGGCGGCGCAGGCTTTCCTCCTGGATGGCGAGACCGGCGCCATCCTTTATTCCAAAAATGCGGATGAGCCTTTCC
CCCCCGCTTCGCTGGCCAAGCTCATGACAGCAGAGCTTCTGCTCAATGCGCTGAAGACCGGTCGGATTTCCATGCAGCGG
GAATTTGAGGTGAGCGAGCATGCCTGGCGCACCGGCGGCGCTCCGTCAGGAACCGCGACCATGTTCGCGGCGGTGAACTC
CAGGGTTCCCATCGAGGCGCTTCTGCAGGGCATTATCGTGCAGCAGGCCAATGACGGCTGCATCATACTTGCCGAGGGGA
TGGCCGGTTCCGAGAATGCATTCGCGCGATTGATGACGGAGCGCGCCCGCGCCCTTGGGCTAACTAGATCTGTTTTCGTC
AATCCTACCGGCTTGCCGGCCGAAGGGCAGCAGGTGACAGTCCGCGAAATAGCACTTTTATCCCGGCATCTCTGGCGGGA
GTACCCCGAATATTACCGCTATTTCGGTCAAGAGGATTTCGAATGGAACCGCATTCGTCAGCGGAACCGCGTCTTACGGC
TTGGGACTGGAGCGGATGGGTTGGCGCTCGGTTTCACGGAAGGCCAGGGTTATGCGATCGCGGCTTCGATGGAGCGCAAC
GGCAAACGGCTTTTCGCCGTTCTTGCGGGAATCCCGGAAGAACAGGAGCGCCCAGAAGAAACGCGCAAAATGCTCGAATG
GGGCTTCAGCGCTTTCGAGCGGCGCCAGCTCTTCACCGCCGGTGAGATAATCGGGGATGCCAATGTCTATGGGGGCGCAA
AGGGCACTGTAGCTCTTCGCGCCGCTGGTCCATTATGGGCGCTTGTGCCGACGGGCGAGTCTCAATCGTTCTCTGCCCGA
ATTGTCTACAATGGGCCGATCTCCGCTCCCGTAGAGGAGGGAGTTGCGGTTGGAAACCTGCAAATCTGGATCGGCGACAC
GTTAAGCCAGGAGATACCGCTCCTCGCAGCTGAATCCGTCGTCAAAGGCACGCTCCGCCAAAGAGCATTTGGCGCCGTGG
AGGAGCTTCTGGTGGGGTGGATGCGTTAG

Upstream 100 bases:

>100_bases
TGAGCTTTGCCAGTTTAGTTTTGCCATATTGCGCCGGGCGGGCTTGAATAGCCGGCCCGGCGTCTAGATTCTAGCGCAGA
ACAGGCAGGAGGGGATTACC

Downstream 100 bases:

>100_bases
CGCAGCTGGATTTGCGCTTAACGCCTCGTCCCATTTTGCCAAACCGGTTCGGCGTTGGACGTCGGCGGCGCGCACGTCTA
TGTAGGACATGCCGAAGCAG

Product: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MIRLASALSLLVLAFVPLPFARAQSFETKAAQAFLLDGETGAILYSKNADEPFPPASLAKLMTAELLLNALKTGRISMQR
EFEVSEHAWRTGGAPSGTATMFAAVNSRVPIEALLQGIIVQQANDGCIILAEGMAGSENAFARLMTERARALGLTRSVFV
NPTGLPAEGQQVTVREIALLSRHLWREYPEYYRYFGQEDFEWNRIRQRNRVLRLGTGADGLALGFTEGQGYAIAASMERN
GKRLFAVLAGIPEEQERPEETRKMLEWGFSAFERRQLFTAGEIIGDANVYGGAKGTVALRAAGPLWALVPTGESQSFSAR
IVYNGPISAPVEEGVAVGNLQIWIGDTLSQEIPLLAAESVVKGTLRQRAFGAVEELLVGWMR

Sequences:

>Translated_382_residues
MIRLASALSLLVLAFVPLPFARAQSFETKAAQAFLLDGETGAILYSKNADEPFPPASLAKLMTAELLLNALKTGRISMQR
EFEVSEHAWRTGGAPSGTATMFAAVNSRVPIEALLQGIIVQQANDGCIILAEGMAGSENAFARLMTERARALGLTRSVFV
NPTGLPAEGQQVTVREIALLSRHLWREYPEYYRYFGQEDFEWNRIRQRNRVLRLGTGADGLALGFTEGQGYAIAASMERN
GKRLFAVLAGIPEEQERPEETRKMLEWGFSAFERRQLFTAGEIIGDANVYGGAKGTVALRAAGPLWALVPTGESQSFSAR
IVYNGPISAPVEEGVAVGNLQIWIGDTLSQEIPLLAAESVVKGTLRQRAFGAVEELLVGWMR
>Mature_382_residues
MIRLASALSLLVLAFVPLPFARAQSFETKAAQAFLLDGETGAILYSKNADEPFPPASLAKLMTAELLLNALKTGRISMQR
EFEVSEHAWRTGGAPSGTATMFAAVNSRVPIEALLQGIIVQQANDGCIILAEGMAGSENAFARLMTERARALGLTRSVFV
NPTGLPAEGQQVTVREIALLSRHLWREYPEYYRYFGQEDFEWNRIRQRNRVLRLGTGADGLALGFTEGQGYAIAASMERN
GKRLFAVLAGIPEEQERPEETRKMLEWGFSAFERRQLFTAGEIIGDANVYGGAKGTVALRAAGPLWALVPTGESQSFSAR
IVYNGPISAPVEEGVAVGNLQIWIGDTLSQEIPLLAAESVVKGTLRQRAFGAVEELLVGWMR

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=389, Percent_Identity=33.1619537275064, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87082022, Length=377, Percent_Identity=31.2997347480106, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1786851, Length=385, Percent_Identity=28.8311688311688, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41634; Mature: 41634

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLASALSLLVLAFVPLPFARAQSFETKAAQAFLLDGETGAILYSKNADEPFPPASLAK
CCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHH
LMTAELLLNALKTGRISMQREFEVSEHAWRTGGAPSGTATMFAAVNSRVPIEALLQGIIV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
QQANDGCIILAEGMAGSENAFARLMTERARALGLTRSVFVNPTGLPAEGQQVTVREIALL
EECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEHHHHHHHH
SRHLWREYPEYYRYFGQEDFEWNRIRQRNRVLRLGTGADGLALGFTEGQGYAIAASMERN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCCCCEEEEEECCCCEEEEEECCCC
GKRLFAVLAGIPEEQERPEETRKMLEWGFSAFERRQLFTAGEIIGDANVYGGAKGTVALR
CCEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
AAGPLWALVPTGESQSFSARIVYNGPISAPVEEGVAVGNLQIWIGDTLSQEIPLLAAESV
ECCCEEEEEECCCCCCEEEEEEECCCCCCCHHCCEEEEEEEEEECCCCCCCCCHHHHHHH
VKGTLRQRAFGAVEELLVGWMR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRLASALSLLVLAFVPLPFARAQSFETKAAQAFLLDGETGAILYSKNADEPFPPASLAK
CCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHH
LMTAELLLNALKTGRISMQREFEVSEHAWRTGGAPSGTATMFAAVNSRVPIEALLQGIIV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
QQANDGCIILAEGMAGSENAFARLMTERARALGLTRSVFVNPTGLPAEGQQVTVREIALL
EECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEHHHHHHHH
SRHLWREYPEYYRYFGQEDFEWNRIRQRNRVLRLGTGADGLALGFTEGQGYAIAASMERN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCCCCEEEEEECCCCEEEEEECCCC
GKRLFAVLAGIPEEQERPEETRKMLEWGFSAFERRQLFTAGEIIGDANVYGGAKGTVALR
CCEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
AAGPLWALVPTGESQSFSARIVYNGPISAPVEEGVAVGNLQIWIGDTLSQEIPLLAAESV
ECCCEEEEEECCCCCCEEEEEEECCCCCCCHHCCEEEEEEEEEECCCCCCCCCHHHHHHH
VKGTLRQRAFGAVEELLVGWMR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]