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The map label for this gene is trkH [H]

Identifier: 110633920

GI number: 110633920

Start: 1684570

End: 1686102

Strand: Reverse

Name: trkH [H]

Synonym: Meso_1567

Alternate gene names: 110633920

Gene position: 1686102-1684570 (Counterclockwise)

Preceding gene: 110633926

Following gene: 110633919

Centisome position: 38.21

GC content: 57.66

Gene sequence:

>1533_bases
ATGCTGGAATTAAAGGAGCATGGGGAGCGTCGCGAACTCAGACCGAAACCAAGCATCAATCTGGAAACCATCCAAGTGCA
CGGCGCAATAATCCGGGCCGCCGCTTATGTGGCCTCTATCTTTTCGATCTATATCGCCGGGGCGATGCTCATTCCGGCGG
CAGTCGACCTTTATTACGGTCATAGCGATTGGCAGGTCTTTGCCGTCTGCGCCTTCACCACGGGGGCCATTGCGCTGACG
GTGGCGGCGGCGACGCGGGACAGGACGCCGGTTCGCTCGACACGGCTGGCCTTCATAGTCGTCGTGGTCTTGTGGTCGAC
CTTGGGGATTGTCGGCGCCTTGCCGCTTTATGCTGCATCGCTGAAGCTCGATTTCGCCGATGCGGTTTTCGAATCCGTTT
CCGCAATCACGACCACTGGCTCCACGGTGGTCGTCGGTCTCGACACTCTTCCTCCTGGCGTGCTGCTCTGGCGCTCGCTC
CTGCAGTGGATGGGCGGATTGGGCGTCGTCGTGCTGGGACTCTTTCTTCTACCGATGCTGAATGTCGGCGGGTTTTCCTA
TTTCCGCATCGAGTCGTCCGATATCGAGGACCGGCCCTTCGAGCGTTTGAAGAGCTTCCTTCGCGCGCTTATAGGCGTTT
ACGTTTTCCTGACGGGGGTGTGCGCCATCGCCTATGCGGCCGCCGGAATGAGCACCTTCGACGCAATCAACCACGCCATG
ACCACGCTCGCCACGGGCGGGATTTCAACGCATGATGCTTCCTTCGGCTTTTTTGAAGACAACAATGTACTGCTGTGGGT
GAGCACTATCTTCATGATCCTGGGTGCCCTTCCCTTTTCAATCCTCATCCTGTTCGTGGTGCAGGGAAGGCTTGATGCCC
TTCGTGATCCGCAGATCCGCGTCTTCCTCGGCTATCTGGTCGTCATTGTCCTGGCCCTTGCCGTGCAGAGACGGATCGCC
GATGACGTCCCATTCGCCGAAGCGGTGACCACGGCTGCTTTCAACATCACGTCCATCGTCAGCACGACAGGCTTCGCCAG
CGAGGACTACACACTCTGGGGACCATTCGCCGTCACGATTGCTTTTTTTGCTACGTTCCTGGGAGGCTGTTCCGGTTCGA
CAACCGGTGGAATCAAGGCATACCGCTTCTTCATTCTTGGACGCATGCTGCGGAACGAACTGCGTATCCTGATTTACGGC
AGTTCGGTGCAACCGCTCAGATACGGCAACCGTGCCGTGGACGCGGAAATGCAGCGGTCGATTGTCCTTTTTTTTATTGC
CTACATTGCCCTTTGGACCGCTGGCACAATCGCACTGGCGGCGAGCAATCTCGATCTTGTGACCGCCGCTAGCTCGATGC
TGACTGCAATCTCAAATGTCGGACCGGGAATTGGCCCAATCGTCGGGCCTGCAGGCAATTTCCTCCCGCTCAGCGATTAT
GCCAAGTGGGTGCTGATTGTCGCCATGCTACTGGGGCGGCTTGAGATTTTTGCCGTGCTTGTCGTTTTTACGCCGACCTT
CTGGCGCGCCTAA

Upstream 100 bases:

>100_bases
AAGTATTATTGCGAACCGTGCCGATCGTTTTGAAAGCCACGGTATCCATGGATCCATTTTACCCCGGGAGTGATCAGCCG
GCGATGCCCCGTCATCAACC

Downstream 100 bases:

>100_bases
CGGGAAGCCCTGAAAGGCGAAGGGTGTTTTGGCTTCATGAGAAAATTGTTATTGTTTTTCGGTCGAAATGGGTCCATTCC
AGAAATATAATTCTAATGGA

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MLELKEHGERRELRPKPSINLETIQVHGAIIRAAAYVASIFSIYIAGAMLIPAAVDLYYGHSDWQVFAVCAFTTGAIALT
VAAATRDRTPVRSTRLAFIVVVVLWSTLGIVGALPLYAASLKLDFADAVFESVSAITTTGSTVVVGLDTLPPGVLLWRSL
LQWMGGLGVVVLGLFLLPMLNVGGFSYFRIESSDIEDRPFERLKSFLRALIGVYVFLTGVCAIAYAAAGMSTFDAINHAM
TTLATGGISTHDASFGFFEDNNVLLWVSTIFMILGALPFSILILFVVQGRLDALRDPQIRVFLGYLVVIVLALAVQRRIA
DDVPFAEAVTTAAFNITSIVSTTGFASEDYTLWGPFAVTIAFFATFLGGCSGSTTGGIKAYRFFILGRMLRNELRILIYG
SSVQPLRYGNRAVDAEMQRSIVLFFIAYIALWTAGTIALAASNLDLVTAASSMLTAISNVGPGIGPIVGPAGNFLPLSDY
AKWVLIVAMLLGRLEIFAVLVVFTPTFWRA

Sequences:

>Translated_510_residues
MLELKEHGERRELRPKPSINLETIQVHGAIIRAAAYVASIFSIYIAGAMLIPAAVDLYYGHSDWQVFAVCAFTTGAIALT
VAAATRDRTPVRSTRLAFIVVVVLWSTLGIVGALPLYAASLKLDFADAVFESVSAITTTGSTVVVGLDTLPPGVLLWRSL
LQWMGGLGVVVLGLFLLPMLNVGGFSYFRIESSDIEDRPFERLKSFLRALIGVYVFLTGVCAIAYAAAGMSTFDAINHAM
TTLATGGISTHDASFGFFEDNNVLLWVSTIFMILGALPFSILILFVVQGRLDALRDPQIRVFLGYLVVIVLALAVQRRIA
DDVPFAEAVTTAAFNITSIVSTTGFASEDYTLWGPFAVTIAFFATFLGGCSGSTTGGIKAYRFFILGRMLRNELRILIYG
SSVQPLRYGNRAVDAEMQRSIVLFFIAYIALWTAGTIALAASNLDLVTAASSMLTAISNVGPGIGPIVGPAGNFLPLSDY
AKWVLIVAMLLGRLEIFAVLVVFTPTFWRA
>Mature_510_residues
MLELKEHGERRELRPKPSINLETIQVHGAIIRAAAYVASIFSIYIAGAMLIPAAVDLYYGHSDWQVFAVCAFTTGAIALT
VAAATRDRTPVRSTRLAFIVVVVLWSTLGIVGALPLYAASLKLDFADAVFESVSAITTTGSTVVVGLDTLPPGVLLWRSL
LQWMGGLGVVVLGLFLLPMLNVGGFSYFRIESSDIEDRPFERLKSFLRALIGVYVFLTGVCAIAYAAAGMSTFDAINHAM
TTLATGGISTHDASFGFFEDNNVLLWVSTIFMILGALPFSILILFVVQGRLDALRDPQIRVFLGYLVVIVLALAVQRRIA
DDVPFAEAVTTAAFNITSIVSTTGFASEDYTLWGPFAVTIAFFATFLGGCSGSTTGGIKAYRFFILGRMLRNELRILIYG
SSVQPLRYGNRAVDAEMQRSIVLFFIAYIALWTAGTIALAASNLDLVTAASSMLTAISNVGPGIGPIVGPAGNFLPLSDY
AKWVLIVAMLLGRLEIFAVLVVFTPTFWRA

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=492, Percent_Identity=36.3821138211382, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1787626, Length=467, Percent_Identity=32.5481798715203, Blast_Score=231, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54980; Mature: 54980

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELKEHGERRELRPKPSINLETIQVHGAIIRAAAYVASIFSIYIAGAMLIPAAVDLYYG
CCCCHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
HSDWQVFAVCAFTTGAIALTVAAATRDRTPVRSTRLAFIVVVVLWSTLGIVGALPLYAAS
CCCCEEEEEEHHHHCHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLDFADAVFESVSAITTTGSTVVVGLDTLPPGVLLWRSLLQWMGGLGVVVLGLFLLPML
HHHHHHHHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NVGGFSYFRIESSDIEDRPFERLKSFLRALIGVYVFLTGVCAIAYAAAGMSTFDAINHAM
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TTLATGGISTHDASFGFFEDNNVLLWVSTIFMILGALPFSILILFVVQGRLDALRDPQIR
HHHHCCCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VFLGYLVVIVLALAVQRRIADDVPFAEAVTTAAFNITSIVSTTGFASEDYTLWGPFAVTI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHH
AFFATFLGGCSGSTTGGIKAYRFFILGRMLRNELRILIYGSSVQPLRYGNRAVDAEMQRS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCHHCHHHHHH
IVLFFIAYIALWTAGTIALAASNLDLVTAASSMLTAISNVGPGIGPIVGPAGNFLPLSDY
HHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
AKWVLIVAMLLGRLEIFAVLVVFTPTFWRA
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MLELKEHGERRELRPKPSINLETIQVHGAIIRAAAYVASIFSIYIAGAMLIPAAVDLYYG
CCCCHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
HSDWQVFAVCAFTTGAIALTVAAATRDRTPVRSTRLAFIVVVVLWSTLGIVGALPLYAAS
CCCCEEEEEEHHHHCHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLDFADAVFESVSAITTTGSTVVVGLDTLPPGVLLWRSLLQWMGGLGVVVLGLFLLPML
HHHHHHHHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NVGGFSYFRIESSDIEDRPFERLKSFLRALIGVYVFLTGVCAIAYAAAGMSTFDAINHAM
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TTLATGGISTHDASFGFFEDNNVLLWVSTIFMILGALPFSILILFVVQGRLDALRDPQIR
HHHHCCCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VFLGYLVVIVLALAVQRRIADDVPFAEAVTTAAFNITSIVSTTGFASEDYTLWGPFAVTI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHH
AFFATFLGGCSGSTTGGIKAYRFFILGRMLRNELRILIYGSSVQPLRYGNRAVDAEMQRS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCHHCHHHHHH
IVLFFIAYIALWTAGTIALAASNLDLVTAASSMLTAISNVGPGIGPIVGPAGNFLPLSDY
HHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
AKWVLIVAMLLGRLEIFAVLVVFTPTFWRA
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]