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The map label for this gene is yomI [H]

Identifier: 110633865

GI number: 110633865

Start: 1611711

End: 1612571

Strand: Reverse

Name: yomI [H]

Synonym: Meso_1512

Alternate gene names: 110633865

Gene position: 1612571-1611711 (Counterclockwise)

Preceding gene: 110633872

Following gene: 110633859

Centisome position: 36.55

GC content: 62.25

Gene sequence:

>861_bases
ATGAAGATGAGAGAGATCAGGGCGGGGATATTATGGCCTTTGGCGGCAATCCTCATGGTCTTTGCTATCTCCTCCGGCCA
GGCCGAGCCCTCTACAAAGAACGACCTTGAGAAGGTTTGCGGGCTGATCGAAGAGCACAGCGCGAAACACGGCCTGTCAC
CCCACTTTCTCGCACGCCTTCTGTGGAAGGAGAGCCGATTCGATCCAAACGCGGTGAGCCCCAAGGGTGCCGAGGGGGTG
GCACAGTTCATGCCGGCTACCGCTTCCCTTCGCGGGCTGACAGATGCTTTCGACGTCGCGCAGGCCGTCCCGGCCTCCGC
CGCCTACCTTTCGGAACTGCGGCAAAGATTTGGCAATCTCGGTTTGGCAGCGGCCGCCTACAACGCCGGGGAAGCGCGTG
TGACCCGATGGCTCTCGAAAGGCGGGTTCCTGCCGCTCGAAACCGAAAACTACGTAAGGGATATTCTGGGCGAACCGGTC
GACGAGTTTGTGAACCGGAACCGGGAAGTCGCGATTCCGCCTCTCGAACCCGACAAAAGCTTCGATGACGCATGCCGGCA
GCTACCCGCAACCGCCTCGGCGACTGTCGCGATGGTGAGCGTTCACACCAAGCCTTGGGGCGTCCAGGTGGCCGGCCATT
TTCGTCGCAGCGTGGCCGTCCGAAAGTGGGAGAGCCTGCGCAAGCGCGTGGGAGTCGTCATTCCGAACGAAGAGCCGGTG
GTTTCCCGCATGCGTTCGCCGCGAAGCCGCAGCGGCATATATGCGGTGCGGTTCGGCGCGGAAACCCGGGCGCAGGCGGA
ACAGATGTGCCGCAAACTGAAAAGCGCCGGCACGAGCTGCATCGTGCTGCGCAATGGCTGA

Upstream 100 bases:

>100_bases
ACACTCGAACGCAAAGCGCATTTTCTTGGAGCTGGCGAGGCAATGAATCTGGGATAAATTTCGCAAGCACCGCATCCAGG
TGCACCAGTTGACGGACGGA

Downstream 100 bases:

>100_bases
GCAATACCCTCTCGGAAGGGGTTGCATGCACCGGACAAACAGGCTAATGAGCGCCGCATTCCTTGGCGATAACCGTGAGG
TTGGCTTTCCGCCCCGGGGC

Product: lytic transglycosylase, catalytic

Products: 1,6-Anhydrobond [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKMREIRAGILWPLAAILMVFAISSGQAEPSTKNDLEKVCGLIEEHSAKHGLSPHFLARLLWKESRFDPNAVSPKGAEGV
AQFMPATASLRGLTDAFDVAQAVPASAAYLSELRQRFGNLGLAAAAYNAGEARVTRWLSKGGFLPLETENYVRDILGEPV
DEFVNRNREVAIPPLEPDKSFDDACRQLPATASATVAMVSVHTKPWGVQVAGHFRRSVAVRKWESLRKRVGVVIPNEEPV
VSRMRSPRSRSGIYAVRFGAETRAQAEQMCRKLKSAGTSCIVLRNG

Sequences:

>Translated_286_residues
MKMREIRAGILWPLAAILMVFAISSGQAEPSTKNDLEKVCGLIEEHSAKHGLSPHFLARLLWKESRFDPNAVSPKGAEGV
AQFMPATASLRGLTDAFDVAQAVPASAAYLSELRQRFGNLGLAAAAYNAGEARVTRWLSKGGFLPLETENYVRDILGEPV
DEFVNRNREVAIPPLEPDKSFDDACRQLPATASATVAMVSVHTKPWGVQVAGHFRRSVAVRKWESLRKRVGVVIPNEEPV
VSRMRSPRSRSGIYAVRFGAETRAQAEQMCRKLKSAGTSCIVLRNG
>Mature_286_residues
MKMREIRAGILWPLAAILMVFAISSGQAEPSTKNDLEKVCGLIEEHSAKHGLSPHFLARLLWKESRFDPNAVSPKGAEGV
AQFMPATASLRGLTDAFDVAQAVPASAAYLSELRQRFGNLGLAAAAYNAGEARVTRWLSKGGFLPLETENYVRDILGEPV
DEFVNRNREVAIPPLEPDKSFDDACRQLPATASATVAMVSVHTKPWGVQVAGHFRRSVAVRKWESLRKRVGVVIPNEEPV
VSRMRSPRSRSGIYAVRFGAETRAQAEQMCRKLKSAGTSCIVLRNG

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 10 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR008258
- InterPro:   IPR016047
- InterPro:   IPR010090
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF10145 PhageMin_Tail; PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 31309; Mature: 31309

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMREIRAGILWPLAAILMVFAISSGQAEPSTKNDLEKVCGLIEEHSAKHGLSPHFLARL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LWKESRFDPNAVSPKGAEGVAQFMPATASLRGLTDAFDVAQAVPASAAYLSELRQRFGNL
HHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
GLAAAAYNAGEARVTRWLSKGGFLPLETENYVRDILGEPVDEFVNRNREVAIPPLEPDKS
CHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHCCCCEEECCCCCCCCC
FDDACRQLPATASATVAMVSVHTKPWGVQVAGHFRRSVAVRKWESLRKRVGVVIPNEEPV
HHHHHHHCCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHH
VSRMRSPRSRSGIYAVRFGAETRAQAEQMCRKLKSAGTSCIVLRNG
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MKMREIRAGILWPLAAILMVFAISSGQAEPSTKNDLEKVCGLIEEHSAKHGLSPHFLARL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LWKESRFDPNAVSPKGAEGVAQFMPATASLRGLTDAFDVAQAVPASAAYLSELRQRFGNL
HHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
GLAAAAYNAGEARVTRWLSKGGFLPLETENYVRDILGEPVDEFVNRNREVAIPPLEPDKS
CHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHCCCCEEECCCCCCCCC
FDDACRQLPATASATVAMVSVHTKPWGVQVAGHFRRSVAVRKWESLRKRVGVVIPNEEPV
HHHHHHHCCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHH
VSRMRSPRSRSGIYAVRFGAETRAQAEQMCRKLKSAGTSCIVLRNG
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]