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The map label for this gene is aspC [H]

Identifier: 110633832

GI number: 110633832

Start: 1576176

End: 1577369

Strand: Reverse

Name: aspC [H]

Synonym: Meso_1479

Alternate gene names: 110633832

Gene position: 1577369-1576176 (Counterclockwise)

Preceding gene: 110633833

Following gene: 110633831

Centisome position: 35.75

GC content: 64.07

Gene sequence:

>1194_bases
ATGCCTGATATTTCAAAGCGCATTACCGGCATCATGCCCTCCGGCAAGGACGGTTGGGAGGTTCATTTCGCAGCCCTGAC
CCGAAAACTGGCGGGTGAAAACATCCTGATGCTCTCGGTGGGCGATCATGATTTCGACACGCCCGCGGGAACGGTCGAGG
CCTGCGTGGAAGCCGTGCAAAGCGGCCATCACCACTATATCCAGCTGCCCGGCCTGCCGAAATTGCGCCAGGCGCTGGCG
CGGCTTTCCACCGAGTGCACCGGCGTCGATACGGCCCCGGAGGAGGTGATCGTCACACAGGGAGGCCAGGGGGCGCTTTA
CGCGTCCTGCCAGGCAGTGCTCGATCCCGGCAGTCATGCGGTGATCGTCTCACCCTATTACGCCACCTATCCCGGCACGG
TACGGGCGGCGGGCGCGAGCTTTACCGAAATCGAAACGCGCTCCGAAGACGGATTTGAGCCGAGGGTCGAGGCGATCGCC
GCCGCGATCCGGCCTGAAACGCGCATGATCCTCATCAATTCGCCGAACAACCCGACGGGCGCCGTCTATTCGCGCGCCAC
TCTCGAGGCAATCGCGGAGATTTGCCGCAGGCACGACCTTTGGCTCCTCTCCGACGAGGTTTACTGGACCTTGCGCGGCG
AGCGGGAGCATGTCTCCCCCCGATCCCTGCCAGGGATGAAGGAGCGCACGCTGGTCGTCAACTCCCTCTCCAAGAGCCAC
GGCATGACAGGCTGGCGCGTCGGCTGGCTCACCGCGCCGGCCGAGGTGGTGAAGCTCCTGATCAGCCTCAACATCGTGTC
GAGCTACGGCATGGTGGATTTCGTCTCGCGCGCGGCAGTGGCGGCGGTGGAAAACGGCCATGGGGTTCAAGAGATCGCGG
CGCGCTACGGAAGCCGCCGAAAGGCCTTCCTGGATGAGATCAGGGGCGCAAACGACATCGTCGTCCGGGGCTCCGAAGGC
GGCATGTATGTCATGCTCGACATTTCGCACATAAATCCGGACGCCGAAGCATTCGCATGGGGCCTCCTGGAGGCGGAAAA
GGTCGCCGTCATGCCCGGACCGAGCTTTGGTGCGGCGGCGCAGGGCCACATCCGCATCTCCATGTGCCAGGAAGAGCCCG
TGCTGCGGGAGGCGGCGATGCGCATCCGCCGCTATATCGCGTCGGAGATCACAAGGCGCGACGCAGCCGAATAG

Upstream 100 bases:

>100_bases
ACTAACGTTCCCGACGAAAGCAGGGCTTGACAATCTGAACCGTGGAGAAGACGGCTTTGCCGTAAAATTGGCCCCGAAGC
CATCAAATAAGAGTAGATTC

Downstream 100 bases:

>100_bases
GGACAGGTCTCTATTTTTTGATGGGAGGGTTGAGCCGTGCTTCAACCCCTCACCTTCTCCCCCGGTTGAGTTCCGGTATC
AGCACCTCTCCAACTTCGTG

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPDISKRITGIMPSGKDGWEVHFAALTRKLAGENILMLSVGDHDFDTPAGTVEACVEAVQSGHHHYIQLPGLPKLRQALA
RLSTECTGVDTAPEEVIVTQGGQGALYASCQAVLDPGSHAVIVSPYYATYPGTVRAAGASFTEIETRSEDGFEPRVEAIA
AAIRPETRMILINSPNNPTGAVYSRATLEAIAEICRRHDLWLLSDEVYWTLRGEREHVSPRSLPGMKERTLVVNSLSKSH
GMTGWRVGWLTAPAEVVKLLISLNIVSSYGMVDFVSRAAVAAVENGHGVQEIAARYGSRRKAFLDEIRGANDIVVRGSEG
GMYVMLDISHINPDAEAFAWGLLEAEKVAVMPGPSFGAAAQGHIRISMCQEEPVLREAAMRIRRYIASEITRRDAAE

Sequences:

>Translated_397_residues
MPDISKRITGIMPSGKDGWEVHFAALTRKLAGENILMLSVGDHDFDTPAGTVEACVEAVQSGHHHYIQLPGLPKLRQALA
RLSTECTGVDTAPEEVIVTQGGQGALYASCQAVLDPGSHAVIVSPYYATYPGTVRAAGASFTEIETRSEDGFEPRVEAIA
AAIRPETRMILINSPNNPTGAVYSRATLEAIAEICRRHDLWLLSDEVYWTLRGEREHVSPRSLPGMKERTLVVNSLSKSH
GMTGWRVGWLTAPAEVVKLLISLNIVSSYGMVDFVSRAAVAAVENGHGVQEIAARYGSRRKAFLDEIRGANDIVVRGSEG
GMYVMLDISHINPDAEAFAWGLLEAEKVAVMPGPSFGAAAQGHIRISMCQEEPVLREAAMRIRRYIASEITRRDAAE
>Mature_396_residues
PDISKRITGIMPSGKDGWEVHFAALTRKLAGENILMLSVGDHDFDTPAGTVEACVEAVQSGHHHYIQLPGLPKLRQALAR
LSTECTGVDTAPEEVIVTQGGQGALYASCQAVLDPGSHAVIVSPYYATYPGTVRAAGASFTEIETRSEDGFEPRVEAIAA
AIRPETRMILINSPNNPTGAVYSRATLEAIAEICRRHDLWLLSDEVYWTLRGEREHVSPRSLPGMKERTLVVNSLSKSHG
MTGWRVGWLTAPAEVVKLLISLNIVSSYGMVDFVSRAAVAAVENGHGVQEIAARYGSRRKAFLDEIRGANDIVVRGSEGG
MYVMLDISHINPDAEAFAWGLLEAEKVAVMPGPSFGAAAQGHIRISMCQEEPVLREAAMRIRRYIASEITRRDAAE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=399, Percent_Identity=28.3208020050125, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI169881279, Length=399, Percent_Identity=28.3208020050125, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713256, Length=333, Percent_Identity=27.9279279279279, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI56713254, Length=333, Percent_Identity=27.9279279279279, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI169881281, Length=306, Percent_Identity=25.4901960784314, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI187936925, Length=348, Percent_Identity=24.4252873563218, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI14211921, Length=348, Percent_Identity=24.4252873563218, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4507369, Length=225, Percent_Identity=24.4444444444444, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=28.3422459893048, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=27.1468144044321, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788627, Length=360, Percent_Identity=28.0555555555556, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790797, Length=226, Percent_Identity=31.858407079646, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787710, Length=215, Percent_Identity=25.5813953488372, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=254, Percent_Identity=32.2834645669291, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=333, Percent_Identity=26.1261261261261, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=333, Percent_Identity=26.1261261261261, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=345, Percent_Identity=22.8985507246377, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=22.5641025641026, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28573069, Length=339, Percent_Identity=28.6135693215339, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646114, Length=339, Percent_Identity=28.6135693215339, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573067, Length=339, Percent_Identity=28.6135693215339, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573065, Length=339, Percent_Identity=28.6135693215339, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=21.5425531914894, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43086; Mature: 42954

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDISKRITGIMPSGKDGWEVHFAALTRKLAGENILMLSVGDHDFDTPAGTVEACVEAVQ
CCCHHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
SGHHHYIQLPGLPKLRQALARLSTECTGVDTAPEEVIVTQGGQGALYASCQAVLDPGSHA
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEHHHHCCCCCCE
VIVSPYYATYPGTVRAAGASFTEIETRSEDGFEPRVEAIAAAIRPETRMILINSPNNPTG
EEECCCEECCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCC
AVYSRATLEAIAEICRRHDLWLLSDEVYWTLRGEREHVSPRSLPGMKERTLVVNSLSKSH
HHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCCCCCCCCCHHEEEEEHHHHHC
GMTGWRVGWLTAPAEVVKLLISLNIVSSYGMVDFVSRAAVAAVENGHGVQEIAARYGSRR
CCCCEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
KAFLDEIRGANDIVVRGSEGGMYVMLDISHINPDAEAFAWGLLEAEKVAVMPGPSFGAAA
HHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCCC
QGHIRISMCQEEPVLREAAMRIRRYIASEITRRDAAE
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDISKRITGIMPSGKDGWEVHFAALTRKLAGENILMLSVGDHDFDTPAGTVEACVEAVQ
CCHHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
SGHHHYIQLPGLPKLRQALARLSTECTGVDTAPEEVIVTQGGQGALYASCQAVLDPGSHA
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEHHHHCCCCCCE
VIVSPYYATYPGTVRAAGASFTEIETRSEDGFEPRVEAIAAAIRPETRMILINSPNNPTG
EEECCCEECCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCC
AVYSRATLEAIAEICRRHDLWLLSDEVYWTLRGEREHVSPRSLPGMKERTLVVNSLSKSH
HHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCCCCCCCCCHHEEEEEHHHHHC
GMTGWRVGWLTAPAEVVKLLISLNIVSSYGMVDFVSRAAVAAVENGHGVQEIAARYGSRR
CCCCEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
KAFLDEIRGANDIVVRGSEGGMYVMLDISHINPDAEAFAWGLLEAEKVAVMPGPSFGAAA
HHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCCC
QGHIRISMCQEEPVLREAAMRIRRYIASEITRRDAAE
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8907187; 10029535 [H]