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The map label for this gene is pitA [C]

Identifier: 110633686

GI number: 110633686

Start: 1427039

End: 1428601

Strand: Reverse

Name: pitA [C]

Synonym: Meso_1333

Alternate gene names: 110633686

Gene position: 1428601-1427039 (Counterclockwise)

Preceding gene: 110633687

Following gene: 110633685

Centisome position: 32.38

GC content: 61.8

Gene sequence:

>1563_bases
ATGACCGACACGCCGATCCAGCCGAAAAAAGAAACACTCGACAAAGACTTGAACAAATTCGTCTATGTCGAGGAAGCGGC
AAGCATCCTCGCGCGGGGTCTTGTGGGGCCGGGCCTTGCCCTGCTTTTCCTTGCGCTCGCCTCGATTTTTGCCGGCTTTT
ATGTGTTTGGCGAGCCGGGTGCGCTCGTCATTATCGCGGCAGCTGCCGTAGGCGCCTATATGGCGCTCAATATCGGCGCC
AACGATGTGGCCAACAATGTCGGGCCTGCCGTCGGTGCCCGCGCCATGACGCTCGGCTCTGCGCTCCTGATCGCGGCTAT
CGCCGAGAGCGCCGGCGCGCTGATTGCCGGCGGCGACGTGGTCGAAACCATTTCCAAGGGCATTGTCGATCCGGCGGCGG
TGGGAGATCCCGGCGTCTTCATCAGCGCCATGCTCGCGGCACTCATCTCGTCCGCTTTGTGGGTTCATCTCGCCACTTGG
ATCGGCGCTCCCGTCTCCACCACCCATGCCGTGGTGGGCGGTGTCATAGGGGCAGGAATCGCCGCAGCCGGGATCTCCTC
GGTCAATTGGCCCATGATGATGCAGATCGCCTTAAGCTGGGTGGTTTCCCCCGTCATGGGCGGTGTGGTGGCGGCCGTTT
TTCTCGCCTTCATAAAAACGATGATCATCTATCGGGATGACAAGATCGCCTCGGCCCGCCGCTGGGTGCCGCTGCTCATC
GCCGTTATGGCGGGCTCTTTTACCGCCTACCTGGCCACAAAGGGGCTGCGGCAGGTGCTCCATGTTCCCAACGGCATGGT
CGCGCTCCTGGGCATTGCGGCCTTCATTCTCACCTGGGCGGCATCCCATGTCCATGTACGCCGCCAGTCGCGTGGCATGG
AAAACCGCAACCAGTCGCTGCGCCGGCTGTTCAATGTGCCGCTCATAATTTCGGCCGCTCTTCTGTCCTTCGCGCATGGA
GCGAACGACGTCGCCAATGCGGTGGGTCCCCTGGCGGCGATCGTTTCCGCCGCTCAAAGCAACACTGTCTCGGCGGAGGT
CGTCATTCCCGTTTGGGTGATGATCATCGGCGCGTTCGGAATCTCGCTGGGCCTGCTGCTTTTTGGACCGAAGCTCATCC
GCATGGTGGGCGAGCAGATCACGAAGCTCAATCCGATGCGCGCCTTCTGCGTGGCGCTTTCGGCTGCGCTTACCGTTATC
ATCGCCTCCGGCATGGGAATGCCGATCAGTTCGACACACACCGCCGTGGGCGCTGTCTTCGGGGTCGGCTTCTTTCGCGA
GTGGTATACGGCCAATTCGAAGCGCCGCCGCGCCTATATCGAACGTAAATATGCCAGCAGGAACGGAAGCGCCCGCAAAT
CCAAAAAACGCAAGGAGCCTGCCGGCGCCAATCACGAGGACGATGAATACGGGACGGCGGGGCTTTCGCGCGAGGAAATC
GTTCGCCGCAAGCTCGTGCGCCGCGCCCATGTCCGCACGATCGTAGCGGCCTGGGTGCTTACCGTACCGGCTTCGGCCGG
CCTTGCCGGCGTCATCTTTCTGCTGCTTGATGCTTTTGCCTAA

Upstream 100 bases:

>100_bases
TTCTGCGTTGGCGTTCGCGCCTTCGTTCATTATTGCCTAGGCGGACCAAACGAGGGGGCGACGCGGTTATGACGCGGATG
CCATTGATTCAAAGCCGCCA

Downstream 100 bases:

>100_bases
CGCACCGGCCCCCACACAGGTATCGGTACGAAAAAGGAGCCTCCTTGTGCGTCCCGAAGGATACGGGGCGCTGCGGACGC
ACAGCCTTCGAGAAATACGG

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTDTPIQPKKETLDKDLNKFVYVEEAASILARGLVGPGLALLFLALASIFAGFYVFGEPGALVIIAAAAVGAYMALNIGA
NDVANNVGPAVGARAMTLGSALLIAAIAESAGALIAGGDVVETISKGIVDPAAVGDPGVFISAMLAALISSALWVHLATW
IGAPVSTTHAVVGGVIGAGIAAAGISSVNWPMMMQIALSWVVSPVMGGVVAAVFLAFIKTMIIYRDDKIASARRWVPLLI
AVMAGSFTAYLATKGLRQVLHVPNGMVALLGIAAFILTWAASHVHVRRQSRGMENRNQSLRRLFNVPLIISAALLSFAHG
ANDVANAVGPLAAIVSAAQSNTVSAEVVIPVWVMIIGAFGISLGLLLFGPKLIRMVGEQITKLNPMRAFCVALSAALTVI
IASGMGMPISSTHTAVGAVFGVGFFREWYTANSKRRRAYIERKYASRNGSARKSKKRKEPAGANHEDDEYGTAGLSREEI
VRRKLVRRAHVRTIVAAWVLTVPASAGLAGVIFLLLDAFA

Sequences:

>Translated_520_residues
MTDTPIQPKKETLDKDLNKFVYVEEAASILARGLVGPGLALLFLALASIFAGFYVFGEPGALVIIAAAAVGAYMALNIGA
NDVANNVGPAVGARAMTLGSALLIAAIAESAGALIAGGDVVETISKGIVDPAAVGDPGVFISAMLAALISSALWVHLATW
IGAPVSTTHAVVGGVIGAGIAAAGISSVNWPMMMQIALSWVVSPVMGGVVAAVFLAFIKTMIIYRDDKIASARRWVPLLI
AVMAGSFTAYLATKGLRQVLHVPNGMVALLGIAAFILTWAASHVHVRRQSRGMENRNQSLRRLFNVPLIISAALLSFAHG
ANDVANAVGPLAAIVSAAQSNTVSAEVVIPVWVMIIGAFGISLGLLLFGPKLIRMVGEQITKLNPMRAFCVALSAALTVI
IASGMGMPISSTHTAVGAVFGVGFFREWYTANSKRRRAYIERKYASRNGSARKSKKRKEPAGANHEDDEYGTAGLSREEI
VRRKLVRRAHVRTIVAAWVLTVPASAGLAGVIFLLLDAFA
>Mature_519_residues
TDTPIQPKKETLDKDLNKFVYVEEAASILARGLVGPGLALLFLALASIFAGFYVFGEPGALVIIAAAAVGAYMALNIGAN
DVANNVGPAVGARAMTLGSALLIAAIAESAGALIAGGDVVETISKGIVDPAAVGDPGVFISAMLAALISSALWVHLATWI
GAPVSTTHAVVGGVIGAGIAAAGISSVNWPMMMQIALSWVVSPVMGGVVAAVFLAFIKTMIIYRDDKIASARRWVPLLIA
VMAGSFTAYLATKGLRQVLHVPNGMVALLGIAAFILTWAASHVHVRRQSRGMENRNQSLRRLFNVPLIISAALLSFAHGA
NDVANAVGPLAAIVSAAQSNTVSAEVVIPVWVMIIGAFGISLGLLLFGPKLIRMVGEQITKLNPMRAFCVALSAALTVII
ASGMGMPISSTHTAVGAVFGVGFFREWYTANSKRRRAYIERKYASRNGSARKSKKRKEPAGANHEDDEYGTAGLSREEIV
RRKLVRRAHVRTIVAAWVLTVPASAGLAGVIFLLLDAFA

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=173, Percent_Identity=33.5260115606936, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI5803173, Length=169, Percent_Identity=33.7278106508876, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25146401, Length=447, Percent_Identity=29.082774049217, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI71981576, Length=395, Percent_Identity=29.3670886075949, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17557328, Length=467, Percent_Identity=25.6959314775161, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32566716, Length=202, Percent_Identity=33.1683168316832, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17539280, Length=284, Percent_Identity=28.169014084507, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536725, Length=147, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6319773, Length=161, Percent_Identity=33.5403726708075, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356511, Length=230, Percent_Identity=31.7391304347826, Blast_Score=112, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 54395; Mature: 54264

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTPIQPKKETLDKDLNKFVYVEEAASILARGLVGPGLALLFLALASIFAGFYVFGEPG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
ALVIIAAAAVGAYMALNIGANDVANNVGPAVGARAMTLGSALLIAAIAESAGALIAGGDV
CEEEHHHHHHHHHHHEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHH
VETISKGIVDPAAVGDPGVFISAMLAALISSALWVHLATWIGAPVSTTHAVVGGVIGAGI
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAAGISSVNWPMMMQIALSWVVSPVMGGVVAAVFLAFIKTMIIYRDDKIASARRWVPLLI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AVMAGSFTAYLATKGLRQVLHVPNGMVALLGIAAFILTWAASHVHVRRQSRGMENRNQSL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RRLFNVPLIISAALLSFAHGANDVANAVGPLAAIVSAAQSNTVSAEVVIPVWVMIIGAFG
HHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ISLGLLLFGPKLIRMVGEQITKLNPMRAFCVALSAALTVIIASGMGMPISSTHTAVGAVF
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
GVGFFREWYTANSKRRRAYIERKYASRNGSARKSKKRKEPAGANHEDDEYGTAGLSREEI
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
VRRKLVRRAHVRTIVAAWVLTVPASAGLAGVIFLLLDAFA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDTPIQPKKETLDKDLNKFVYVEEAASILARGLVGPGLALLFLALASIFAGFYVFGEPG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
ALVIIAAAAVGAYMALNIGANDVANNVGPAVGARAMTLGSALLIAAIAESAGALIAGGDV
CEEEHHHHHHHHHHHEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHH
VETISKGIVDPAAVGDPGVFISAMLAALISSALWVHLATWIGAPVSTTHAVVGGVIGAGI
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAAGISSVNWPMMMQIALSWVVSPVMGGVVAAVFLAFIKTMIIYRDDKIASARRWVPLLI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AVMAGSFTAYLATKGLRQVLHVPNGMVALLGIAAFILTWAASHVHVRRQSRGMENRNQSL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RRLFNVPLIISAALLSFAHGANDVANAVGPLAAIVSAAQSNTVSAEVVIPVWVMIIGAFG
HHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ISLGLLLFGPKLIRMVGEQITKLNPMRAFCVALSAALTVIIASGMGMPISSTHTAVGAVF
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
GVGFFREWYTANSKRRRAYIERKYASRNGSARKSKKRKEPAGANHEDDEYGTAGLSREEI
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
VRRKLVRRAHVRTIVAAWVLTVPASAGLAGVIFLLLDAFA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]