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The map label for this gene is dnaB [H]

Identifier: 110633557

GI number: 110633557

Start: 1306747

End: 1308192

Strand: Direct

Name: dnaB [H]

Synonym: Meso_1204

Alternate gene names: 110633557

Gene position: 1306747-1308192 (Clockwise)

Preceding gene: 110633556

Following gene: 110633558

Centisome position: 29.62

GC content: 62.03

Gene sequence:

>1446_bases
ATGAACGCGCTCGCCGATCCCATCCGCGAAGTCCCGCACAACATCGAAGCCGAGCAAGCACTGCTCGGCGCCGTGATGGT
GAACAACGCCTGCTACGACCTGGTCTCGCGTATAGTGCGGCCTGAGCACTTCTTTGAGCCGCTGCACCGCGACATCTTCA
AGGCCTCGGGGGATCTGATCACCGTCGGCCGCAGAGCGGACCCGATCACCCTGCGCGATTTCCTCCCGGCCGATGCCAAG
GTCGGAGAGATGACCGTCGCGCAATACCTCGCCGCGCTCTGCGCCGATGCTGTGACGATCGTCATGGCACGGGATTATGC
AGCCTCGATCTTCGACGCTTGGATGTCCCGGCAGATCATCGTCGCCTGCGAGGACACGGTTGCCAAGCTCTACCAGAGGC
GCCCGGGCATGGACCCGCTGACGGAGGCGGGCCCGGTCGAGGATATGCTTGCCAAGCTCCGCGCCGAGCGCGTGAGCGCC
AGCGGAACAGCTTCCCATGGCCGGCAGTACCTTCAGAGCCTCACAGAGGCCCGCCAGCGGGGCAAGGTGCTCGGCGTGCC
GATCTGCCTGCCGGAGATTGCCGCGGTCATCTCCGAGCCGTCATTCGAGGCAGGAAACCTCTACGGGCTTCTTTCCTCAT
CAGGCGAGGGCAAGACCTCGCTCACCCTGCAGATCATCATGCACGCGCTAAAGAAGGGGCATCCTGTCCAGTTCCTGAGC
TTCGACCAATCCGCGGAGCAGTGCATCCGGCAATTGGTGGCGCAAGAGCACGGTATAGAGGCGCGCCGGCAGCGGGCAGG
CGACCTCTCCGAAAAGGAATGGGAGACGGTCGTCGACTTCTCCAACTGGATGGATCGGGAGCCTTTCGAGGTGGTCAAAT
GCACAGATCATAGCGCGCCGCAGCTCCTCGCCTTCGCCCGCGCCTTCGTGAAGCGCTTCGGCAACGGAAATGTCCCGCTG
ATCGTCGTTGACCATATCGGCGCCGTGAAGCCGGAAGACAGGCGCGCGGACGAGGGCACCAAGGCCAAGGACATCAACAA
GGTGTTTAAGGCTGGTGCCGAGCAGACGGGCGCCGCCTGGCTCATCCTCAATCAGCGCAACAGCTACGGCATGAAGCGCG
ACAACCCCCGGCCAATCTCAGCGGACCTTTTTGGCGGTGATCCGGCCAAGCAGGCCTACGACGCCATCTTCTATGTCTAT
CGCTACCTGAAATTCCTTGAGGAGCGGAAGGCCATCGCCTCGTCTGAGAGCGACTGGAAGAAAATTGCGAAGGTGTTCCC
ATCAGCTGTTCGCGAGGGTGGTGAGGACATTGCCCAGATCGGGGCCATTAAGGTTCGCTTCGGCAATGCCGCCATCACCC
GGAATCTCATCTTCGAGGCTCGTTTTACCCGCTATCGCAGCGAGCAGATGAACGACCAGCCCGAGCTTATGGAGGCGATG
CTTTGA

Upstream 100 bases:

>100_bases
CCCCACGCCATCTGTGGATTCTCCCATCCCTGCCCATTTCGGAAAGGGAACAGGCAATCGGGATCTCAGTCAACGGCTTG
GTACTTGGGAGGGCGATCGG

Downstream 100 bases:

>100_bases
ATCACTCCACGGCATTCGCGGAGACGACCATAGGCGGCGCCTATATCGGACGCTTCCGAGTAGCGTGGCGCTCCGAGGCC
TTCCTGGTGAGAGAGCATAG

Product: DnaB-like helicase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNALADPIREVPHNIEAEQALLGAVMVNNACYDLVSRIVRPEHFFEPLHRDIFKASGDLITVGRRADPITLRDFLPADAK
VGEMTVAQYLAALCADAVTIVMARDYAASIFDAWMSRQIIVACEDTVAKLYQRRPGMDPLTEAGPVEDMLAKLRAERVSA
SGTASHGRQYLQSLTEARQRGKVLGVPICLPEIAAVISEPSFEAGNLYGLLSSSGEGKTSLTLQIIMHALKKGHPVQFLS
FDQSAEQCIRQLVAQEHGIEARRQRAGDLSEKEWETVVDFSNWMDREPFEVVKCTDHSAPQLLAFARAFVKRFGNGNVPL
IVVDHIGAVKPEDRRADEGTKAKDINKVFKAGAEQTGAAWLILNQRNSYGMKRDNPRPISADLFGGDPAKQAYDAIFYVY
RYLKFLEERKAIASSESDWKKIAKVFPSAVREGGEDIAQIGAIKVRFGNAAITRNLIFEARFTRYRSEQMNDQPELMEAM
L

Sequences:

>Translated_481_residues
MNALADPIREVPHNIEAEQALLGAVMVNNACYDLVSRIVRPEHFFEPLHRDIFKASGDLITVGRRADPITLRDFLPADAK
VGEMTVAQYLAALCADAVTIVMARDYAASIFDAWMSRQIIVACEDTVAKLYQRRPGMDPLTEAGPVEDMLAKLRAERVSA
SGTASHGRQYLQSLTEARQRGKVLGVPICLPEIAAVISEPSFEAGNLYGLLSSSGEGKTSLTLQIIMHALKKGHPVQFLS
FDQSAEQCIRQLVAQEHGIEARRQRAGDLSEKEWETVVDFSNWMDREPFEVVKCTDHSAPQLLAFARAFVKRFGNGNVPL
IVVDHIGAVKPEDRRADEGTKAKDINKVFKAGAEQTGAAWLILNQRNSYGMKRDNPRPISADLFGGDPAKQAYDAIFYVY
RYLKFLEERKAIASSESDWKKIAKVFPSAVREGGEDIAQIGAIKVRFGNAAITRNLIFEARFTRYRSEQMNDQPELMEAM
L
>Mature_481_residues
MNALADPIREVPHNIEAEQALLGAVMVNNACYDLVSRIVRPEHFFEPLHRDIFKASGDLITVGRRADPITLRDFLPADAK
VGEMTVAQYLAALCADAVTIVMARDYAASIFDAWMSRQIIVACEDTVAKLYQRRPGMDPLTEAGPVEDMLAKLRAERVSA
SGTASHGRQYLQSLTEARQRGKVLGVPICLPEIAAVISEPSFEAGNLYGLLSSSGEGKTSLTLQIIMHALKKGHPVQFLS
FDQSAEQCIRQLVAQEHGIEARRQRAGDLSEKEWETVVDFSNWMDREPFEVVKCTDHSAPQLLAFARAFVKRFGNGNVPL
IVVDHIGAVKPEDRRADEGTKAKDINKVFKAGAEQTGAAWLILNQRNSYGMKRDNPRPISADLFGGDPAKQAYDAIFYVY
RYLKFLEERKAIASSESDWKKIAKVFPSAVREGGEDIAQIGAIKVRFGNAAITRNLIFEARFTRYRSEQMNDQPELMEAM
L

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=477, Percent_Identity=21.3836477987421, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 53476; Mature: 53476

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALADPIREVPHNIEAEQALLGAVMVNNACYDLVSRIVRPEHFFEPLHRDIFKASGDLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEE
TVGRRADPITLRDFLPADAKVGEMTVAQYLAALCADAVTIVMARDYAASIFDAWMSRQII
EECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VACEDTVAKLYQRRPGMDPLTEAGPVEDMLAKLRAERVSASGTASHGRQYLQSLTEARQR
EEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GKVLGVPICLPEIAAVISEPSFEAGNLYGLLSSSGEGKTSLTLQIIMHALKKGHPVQFLS
CCEEECCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FDQSAEQCIRQLVAQEHGIEARRQRAGDLSEKEWETVVDFSNWMDREPFEVVKCTDHSAP
CCHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
QLLAFARAFVKRFGNGNVPLIVVDHIGAVKPEDRRADEGTKAKDINKVFKAGAEQTGAAW
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEE
LILNQRNSYGMKRDNPRPISADLFGGDPAKQAYDAIFYVYRYLKFLEERKAIASSESDWK
EEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KIAKVFPSAVREGGEDIAQIGAIKVRFGNAAITRNLIFEARFTRYRSEQMNDQPELMEAM
HHHHHHHHHHHHCCHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
L
C
>Mature Secondary Structure
MNALADPIREVPHNIEAEQALLGAVMVNNACYDLVSRIVRPEHFFEPLHRDIFKASGDLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEE
TVGRRADPITLRDFLPADAKVGEMTVAQYLAALCADAVTIVMARDYAASIFDAWMSRQII
EECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VACEDTVAKLYQRRPGMDPLTEAGPVEDMLAKLRAERVSASGTASHGRQYLQSLTEARQR
EEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GKVLGVPICLPEIAAVISEPSFEAGNLYGLLSSSGEGKTSLTLQIIMHALKKGHPVQFLS
CCEEECCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FDQSAEQCIRQLVAQEHGIEARRQRAGDLSEKEWETVVDFSNWMDREPFEVVKCTDHSAP
CCHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
QLLAFARAFVKRFGNGNVPLIVVDHIGAVKPEDRRADEGTKAKDINKVFKAGAEQTGAAW
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEE
LILNQRNSYGMKRDNPRPISADLFGGDPAKQAYDAIFYVYRYLKFLEERKAIASSESDWK
EEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KIAKVFPSAVREGGEDIAQIGAIKVRFGNAAITRNLIFEARFTRYRSEQMNDQPELMEAM
HHHHHHHHHHHHCCHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA