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The map label for this gene is zmpB [H]

Identifier: 110633478

GI number: 110633478

Start: 1232978

End: 1234444

Strand: Reverse

Name: zmpB [H]

Synonym: Meso_1125

Alternate gene names: 110633478

Gene position: 1234444-1232978 (Counterclockwise)

Preceding gene: 110633480

Following gene: 110633476

Centisome position: 27.98

GC content: 63.87

Gene sequence:

>1467_bases
TTGGCTGGCAGAAGAATTTTGGAGGATACTGCCGTGAAGAAGCTTCTTATCGGCGTGGCTGCGGTCGCGCTTTTATCTTC
CCCATCGATTGCACCCCAAATTGTCTTTCCAGGCGTCCAGGAGGCGCATGCGCAGGGTGCTGAGGTCAGCATCAGCGTGT
TCTATGACCGCTTGGCCGACCATGGTTCCTGGGTCAGCCATCCTCGGCATCAATATGTCTGGGTGCCGACTGATGTCGAT
GCAAGCTGGGTGCCCTACTCCCATGGCCACTGGGTCTATACGGAGCAGTATGGCTGGTATTTCGCTTCGGATGAACCCTT
TGCCTGGGCGGTTTATCACTACGGCCGCTGGGGCTATGATCCGGAAATCGGCTGGTTCTGGGTACCGGGAACCCGCTGGG
CACCCGCCTGGGTTTCCTGGCGGCGCGGAGATGACCATGTCGGCTGGGCGCCGCTGCCCCCCGAAGGCGATGGAATCGCC
GTCAGCGTGGAAATTTCTGCCGAACCGCCCGAAGGCTATTGGGTATTCGTGCCCGTCAATGAGTTCGTTGCCCCGGATCT
CGCCGTCGTGATCATCGCGCGGGACGAGGTGCCGGTTATCTATCAGCGGACCGAGCTGGTGGGGCCGGTCGAGGTTGAAA
ACAATATTGTCGTCAACAACGTGATCGATATCGATTACATCGAGCAGCATGTGGACGAGGACATCGAGGTCACACAGGTT
CAGGAGGTCCAGGACCCGGCTGAAGCTGCCCAAAGCGATGGTGTAGTCGCCTTCACCGGCGAGATCGCCGCTGAGCAGGA
TGCAGCCCCTGCGGAAGCGGTTGAGGCCGCACAGGTGGAATCGCCGACCAGAGGCCAGGAGATCGAGGCAACCGGCGAGG
CGACATCGGAGCAAGGCGAGGGGGCTCCGGCCGGAGAGACGGAACAAGCGCCCGCTGAAGGCGCGGAGCCGACGGATCAA
GAAACCGAGCAGGCACCGGCCGAGGAAACAGAGCAGACACCGGCGGATCAGGAGTCCACGGAGCAGCCTGCCGACCAAGA
ACCCACGGCCGAAGCGCCTTCCGACCAGCAGCCCGCCGAAGAGGAGGCCCCTGCCGACCAGCAGGAAGCTCCCGCTGAAG
AACAGCCTGCCGAGGAACAACCCGCCGAGGAGCAGCCGGCAGAGAGCCAGCCGGAGGCGGAGCAGGCACCGGCCGAAGAA
GCAGCCCCCGCAGAAGAAGCGCCTGCCCCGCAGGAACCTACAGGCGAGGCTGAGGAAGCGCCGGCAGAGCAAGAGCAGCC
CGCCGAAGCAGGCGAACAGGAAGCGCCCGCTGGCGAGACTGAGCAGGCTCCCGAGGGCGCCGAAGAGGCTCCTGCTGAGG
GCGCCGAAGAGGCGCCAGTGGAAGGCGCCGAGGAGGCTCCTGCCGAAGGTGAACAGGCTCCCGCGGAAGAATGCGCGCCG
GAGGCGCGGGAAGCCGGCGAATGTTAA

Upstream 100 bases:

>100_bases
CGGCTTCAACAAATCTAATTTCCGTATCATCTCTTCTTTTTCTGTGTTCGCAATCTTCATCCAAACGCGCAGGAGCTGGA
ACAAATCTTCTTCTCCCTAG

Downstream 100 bases:

>100_bases
AATAACGATAGTTCCAGGACCCCCGCTGCAGCGGGGGTTCTTATTTCAGCCGTGCAGGCGGTTCCGGACGGCGGGCCGTC
TTTCGCTTACTCCCGCTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MAGRRILEDTAVKKLLIGVAAVALLSSPSIAPQIVFPGVQEAHAQGAEVSISVFYDRLADHGSWVSHPRHQYVWVPTDVD
ASWVPYSHGHWVYTEQYGWYFASDEPFAWAVYHYGRWGYDPEIGWFWVPGTRWAPAWVSWRRGDDHVGWAPLPPEGDGIA
VSVEISAEPPEGYWVFVPVNEFVAPDLAVVIIARDEVPVIYQRTELVGPVEVENNIVVNNVIDIDYIEQHVDEDIEVTQV
QEVQDPAEAAQSDGVVAFTGEIAAEQDAAPAEAVEAAQVESPTRGQEIEATGEATSEQGEGAPAGETEQAPAEGAEPTDQ
ETEQAPAEETEQTPADQESTEQPADQEPTAEAPSDQQPAEEEAPADQQEAPAEEQPAEEQPAEEQPAESQPEAEQAPAEE
AAPAEEAPAPQEPTGEAEEAPAEQEQPAEAGEQEAPAGETEQAPEGAEEAPAEGAEEAPVEGAEEAPAEGEQAPAEECAP
EAREAGEC

Sequences:

>Translated_488_residues
MAGRRILEDTAVKKLLIGVAAVALLSSPSIAPQIVFPGVQEAHAQGAEVSISVFYDRLADHGSWVSHPRHQYVWVPTDVD
ASWVPYSHGHWVYTEQYGWYFASDEPFAWAVYHYGRWGYDPEIGWFWVPGTRWAPAWVSWRRGDDHVGWAPLPPEGDGIA
VSVEISAEPPEGYWVFVPVNEFVAPDLAVVIIARDEVPVIYQRTELVGPVEVENNIVVNNVIDIDYIEQHVDEDIEVTQV
QEVQDPAEAAQSDGVVAFTGEIAAEQDAAPAEAVEAAQVESPTRGQEIEATGEATSEQGEGAPAGETEQAPAEGAEPTDQ
ETEQAPAEETEQTPADQESTEQPADQEPTAEAPSDQQPAEEEAPADQQEAPAEEQPAEEQPAEEQPAESQPEAEQAPAEE
AAPAEEAPAPQEPTGEAEEAPAEQEQPAEAGEQEAPAGETEQAPEGAEEAPAEGAEEAPVEGAEEAPAEGEQAPAEECAP
EAREAGEC
>Mature_487_residues
AGRRILEDTAVKKLLIGVAAVALLSSPSIAPQIVFPGVQEAHAQGAEVSISVFYDRLADHGSWVSHPRHQYVWVPTDVDA
SWVPYSHGHWVYTEQYGWYFASDEPFAWAVYHYGRWGYDPEIGWFWVPGTRWAPAWVSWRRGDDHVGWAPLPPEGDGIAV
SVEISAEPPEGYWVFVPVNEFVAPDLAVVIIARDEVPVIYQRTELVGPVEVENNIVVNNVIDIDYIEQHVDEDIEVTQVQ
EVQDPAEAAQSDGVVAFTGEIAAEQDAAPAEAVEAAQVESPTRGQEIEATGEATSEQGEGAPAGETEQAPAEGAEPTDQE
TEQAPAEETEQTPADQESTEQPADQEPTAEAPSDQQPAEEEAPADQQEAPAEEQPAEEQPAEEQPAESQPEAEQAPAEEA
APAEEAPAPQEPTGEAEEAPAEQEQPAEAGEQEAPAGETEQAPEGAEEAPAEGAEEAPVEGAEEAPAEGEQAPAEECAPE
AREAGEC

Specific function: Is a virulence factor capable of inducing inflammation in the lower respiratory tract, by increasing tumor necrosis factor alpha (TNF-alpha) concentration in the lungs. Also appears to have other functions important in virulence in models of pneumonia and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall. Membrane; Multi-pass membrane protein. Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR008006
- InterPro:   IPR011505 [H]

Pfam domain/function: PF00746 Gram_pos_anchor; PF07580 Peptidase_M26_C; PF05342 Peptidase_M26_N [H]

EC number: NA

Molecular weight: Translated: 52370; Mature: 52239

Theoretical pI: Translated: 3.48; Mature: 3.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRRILEDTAVKKLLIGVAAVALLSSPSIAPQIVFPGVQEAHAQGAEVSISVFYDRLAD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCEEEEHHHHHHHHC
HGSWVSHPRHQYVWVPTDVDASWVPYSHGHWVYTEQYGWYFASDEPFAWAVYHYGRWGYD
CCCHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCEEEECCCCEEEEEEECCCCCCC
PEIGWFWVPGTRWAPAWVSWRRGDDHVGWAPLPPEGDGIAVSVEISAEPPEGYWVFVPVN
CCCCEEECCCCCCCCHHEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECH
EFVAPDLAVVIIARDEVPVIYQRTELVGPVEVENNIVVNNVIDIDYIEQHVDEDIEVTQV
HHHCCCEEEEEEECCCCCEEEECCCCCCCEECCCCEEEECEECHHHHHHHCCCCCCHHHH
QEVQDPAEAAQSDGVVAFTGEIAAEQDAAPAEAVEAAQVESPTRGQEIEATGEATSEQGE
HHHHCHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCC
GAPAGETEQAPAEGAEPTDQETEQAPAEETEQTPADQESTEQPADQEPTAEAPSDQQPAE
CCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCH
EEAPADQQEAPAEEQPAEEQPAEEQPAESQPEAEQAPAEEAAPAEEAPAPQEPTGEAEEA
HHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCHHHC
PAEQEQPAEAGEQEAPAGETEQAPEGAEEAPAEGAEEAPVEGAEEAPAEGEQAPAEECAP
CCCCCCCHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCH
EAREAGEC
HHHHCCCC
>Mature Secondary Structure 
AGRRILEDTAVKKLLIGVAAVALLSSPSIAPQIVFPGVQEAHAQGAEVSISVFYDRLAD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCEEEEHHHHHHHHC
HGSWVSHPRHQYVWVPTDVDASWVPYSHGHWVYTEQYGWYFASDEPFAWAVYHYGRWGYD
CCCHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCEEEECCCCEEEEEEECCCCCCC
PEIGWFWVPGTRWAPAWVSWRRGDDHVGWAPLPPEGDGIAVSVEISAEPPEGYWVFVPVN
CCCCEEECCCCCCCCHHEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECH
EFVAPDLAVVIIARDEVPVIYQRTELVGPVEVENNIVVNNVIDIDYIEQHVDEDIEVTQV
HHHCCCEEEEEEECCCCCEEEECCCCCCCEECCCCEEEECEECHHHHHHHCCCCCCHHHH
QEVQDPAEAAQSDGVVAFTGEIAAEQDAAPAEAVEAAQVESPTRGQEIEATGEATSEQGE
HHHHCHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCC
GAPAGETEQAPAEGAEPTDQETEQAPAEETEQTPADQESTEQPADQEPTAEAPSDQQPAE
CCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCH
EEAPADQQEAPAEEQPAEEQPAEEQPAESQPEAEQAPAEEAAPAEEAPAPQEPTGEAEEA
HHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCHHHC
PAEQEQPAEAGEQEAPAGETEQAPEGAEEAPAEGAEEAPVEGAEEAPAEGEQAPAEECAP
CCCCCCCHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCH
EAREAGEC
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10792723; 11463916 [H]