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The map label for this gene is siaT [H]

Identifier: 110633445

GI number: 110633445

Start: 1195884

End: 1197809

Strand: Direct

Name: siaT [H]

Synonym: Meso_1091

Alternate gene names: 110633445

Gene position: 1195884-1197809 (Clockwise)

Preceding gene: 110633444

Following gene: 110633446

Centisome position: 27.1

GC content: 64.12

Gene sequence:

>1926_bases
ATGTCCAGCCAAGCTAAACCGGTCGTCCCTCCCATATTGCTCGTCCTCACGACCCTTACCGTGCTCTGGCACGTCGTGAC
GATAGCGCAGTTGCCCACTTGGTTCGGCATCTTCATTCCTCAGGCGTCGATCCGGGCCACGAGCCTCGTGCTTGCCGCTG
TGCTGATCCTGCTCACCTCCCATGCCGCGAGCGGCCATGAGGGCGAACCGCTTAAGGACGGCGTCCGCTTCCGCTGGCTC
GACCTTCTGGTGTTCGCGCCGCTTGCCGCAGGCTGCAGCCTTGTCATTTTCAACTACGACAAGGTGCTGGACTACGGCTT
CTTCGGTGCGCTCGACACCACCGGCGTCATTCTGGCGCTCTGCGTCGCCGTTCCCCTCCTGGAACTCGTGCGCCGCAAGA
CTGGGATCGTATTGCCGATCATCATCCTGAGCTTCGTCGCCATTGCGATGTTCCAGGCCTATCTGCCCGGAGTCCTGCAC
GGCCGAGGCTATTCGCTCGACCGGCTCCGTTACTCTTCCTATGTCGGCGAATCCGGGATATTCGGCGCGCCGCTCGGCAT
CGCCGTCAATATCGTAATGGTCTACTTGCTGTTCGGCGCTCTGATGGAGAGGGCAGGGGCCAGCCGCTGGTTTATGGATC
TCGCGCTCTCACTCACCGGCCGGTCGAGCGGCGGTCCGGCCAAGGCGTCCGTCGTCGCTTCCGCTATGTTCGGCTCCATC
TCTGGCTCGCCCTCGGGCAACGCCGCCACCACTGGCGTGTTCACCATTCCGATGATGCGCGAGGTGGGCTATAAGCCGAG
CTTCGCCGCTGCCGTTGAAGCGGTGGCATCGACCGGGGGCATGATCCTGCCGCCGGTGATGGGGGCCATTGCCTTCCTCA
TGGCCGAATGGATCGGCCGCACCTATCGCGAAGTCGTCATCGCGGCGCTGATCCCGGCGATCCTCTACTTCATCGTGATC
TTCGCGTCGGTGCATTTCGAGGCAAAGCGCTCGGGTATCCGTGCTATGGCGCGCACCGACCTCCCTGCCTTCTGGAAGAC
GCTGCGCAGCGGCTGGTACTACGCGCTGCCCATGCTGGCGCTGATCTGGTTCCTGATCATCGCCGCGTTGCCGCCGGGAA
TGGCAGGGATTTATTGCTGCGGCGTGGTTCTGCTCTGCTCGTTCCTGTCGCCCGATCGCTCGCGCTGGCTCCTGCCAAGG
CCTCTGCTTCTCGCGATGAAAGACGCAGTGATGCGCTGGCTCGTCATCGTCGTCATCACCGCTTCCGTCGGCATCATGAT
TGGCGCGATGGAACTCTCGGGCGTCGGCCTCAACGTCTCGCGCTTCATCGTCGATATCGGCGGCGGCAACCTTGTCGTCA
CGCTGGTCCTCGTCGGGGCTGTCAGCCTCCTGATCGGCATGGGACTCGACGCGACCCCGGCCTACGTGACGCTCGCCACG
CTCATGGCCCCTGCGCTGATTCAGATGGGCGTTCAGGACATCGCAGCGCACCTGTTCGTGGTCTATTGGGGCCTTGCCTC
TTTCTTCACACCGCCAACCTGCATCGCGATTTTCGTTACCGCTCCGATGGCCGGCGCGAGCGTCTGGGCGGCGGGCTGGC
AGGCCGTGCGCCTTGGCATCGCGGCCTTCCTTGTGCCGATGAGCTTTGCGCTGAACCCCGCCCTGCTCATGGAGGGGGCC
GTCAGAGAGATCATCCTCGCCACCGGCACCGCGCTGGTTGGTGCAGTCGCACTTTCCGCGGGTCTTCGCGGCTTCGCATT
ACAGCGGCTCAGCGGAGCTGAGCGCGCGCTGATCTCACTCGGCGGTGTTCTCCTGATTGCACCGGGCATCGCGCCCGCCC
TCATTGGGCTGGGCCTCGTCGTCGGAGTGGTGGTCTGGTCGACCTGGCTTCAATCCGTCCGTCCAGTGCGGGAGGGGTCG
CCGTGA

Upstream 100 bases:

>100_bases
TCCAGGCCAAGCAGGACAAGCTCCTCACCCGTTGATCTTTCACCCGTTCCAGGCTGCCGCGCGTGGCCCGGAACCTCGCG
TGTCCACGGGTTCAGCACTG

Downstream 100 bases:

>100_bases
CGACTCTCGCATGGGGTGACGCTCAGGAACATCGCCGTCGCGAAAGATGCAGGACCAAGCCGCGATGACACGCGAGATGG
TCCGCTAGGCGAGCTGCGCA

Product: TRAP transporter, 4TM/12TM fusion protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MSSQAKPVVPPILLVLTTLTVLWHVVTIAQLPTWFGIFIPQASIRATSLVLAAVLILLTSHAASGHEGEPLKDGVRFRWL
DLLVFAPLAAGCSLVIFNYDKVLDYGFFGALDTTGVILALCVAVPLLELVRRKTGIVLPIIILSFVAIAMFQAYLPGVLH
GRGYSLDRLRYSSYVGESGIFGAPLGIAVNIVMVYLLFGALMERAGASRWFMDLALSLTGRSSGGPAKASVVASAMFGSI
SGSPSGNAATTGVFTIPMMREVGYKPSFAAAVEAVASTGGMILPPVMGAIAFLMAEWIGRTYREVVIAALIPAILYFIVI
FASVHFEAKRSGIRAMARTDLPAFWKTLRSGWYYALPMLALIWFLIIAALPPGMAGIYCCGVVLLCSFLSPDRSRWLLPR
PLLLAMKDAVMRWLVIVVITASVGIMIGAMELSGVGLNVSRFIVDIGGGNLVVTLVLVGAVSLLIGMGLDATPAYVTLAT
LMAPALIQMGVQDIAAHLFVVYWGLASFFTPPTCIAIFVTAPMAGASVWAAGWQAVRLGIAAFLVPMSFALNPALLMEGA
VREIILATGTALVGAVALSAGLRGFALQRLSGAERALISLGGVLLIAPGIAPALIGLGLVVGVVVWSTWLQSVRPVREGS
P

Sequences:

>Translated_641_residues
MSSQAKPVVPPILLVLTTLTVLWHVVTIAQLPTWFGIFIPQASIRATSLVLAAVLILLTSHAASGHEGEPLKDGVRFRWL
DLLVFAPLAAGCSLVIFNYDKVLDYGFFGALDTTGVILALCVAVPLLELVRRKTGIVLPIIILSFVAIAMFQAYLPGVLH
GRGYSLDRLRYSSYVGESGIFGAPLGIAVNIVMVYLLFGALMERAGASRWFMDLALSLTGRSSGGPAKASVVASAMFGSI
SGSPSGNAATTGVFTIPMMREVGYKPSFAAAVEAVASTGGMILPPVMGAIAFLMAEWIGRTYREVVIAALIPAILYFIVI
FASVHFEAKRSGIRAMARTDLPAFWKTLRSGWYYALPMLALIWFLIIAALPPGMAGIYCCGVVLLCSFLSPDRSRWLLPR
PLLLAMKDAVMRWLVIVVITASVGIMIGAMELSGVGLNVSRFIVDIGGGNLVVTLVLVGAVSLLIGMGLDATPAYVTLAT
LMAPALIQMGVQDIAAHLFVVYWGLASFFTPPTCIAIFVTAPMAGASVWAAGWQAVRLGIAAFLVPMSFALNPALLMEGA
VREIILATGTALVGAVALSAGLRGFALQRLSGAERALISLGGVLLIAPGIAPALIGLGLVVGVVVWSTWLQSVRPVREGS
P
>Mature_640_residues
SSQAKPVVPPILLVLTTLTVLWHVVTIAQLPTWFGIFIPQASIRATSLVLAAVLILLTSHAASGHEGEPLKDGVRFRWLD
LLVFAPLAAGCSLVIFNYDKVLDYGFFGALDTTGVILALCVAVPLLELVRRKTGIVLPIIILSFVAIAMFQAYLPGVLHG
RGYSLDRLRYSSYVGESGIFGAPLGIAVNIVMVYLLFGALMERAGASRWFMDLALSLTGRSSGGPAKASVVASAMFGSIS
GSPSGNAATTGVFTIPMMREVGYKPSFAAAVEAVASTGGMILPPVMGAIAFLMAEWIGRTYREVVIAALIPAILYFIVIF
ASVHFEAKRSGIRAMARTDLPAFWKTLRSGWYYALPMLALIWFLIIAALPPGMAGIYCCGVVLLCSFLSPDRSRWLLPRP
LLLAMKDAVMRWLVIVVITASVGIMIGAMELSGVGLNVSRFIVDIGGGNLVVTLVLVGAVSLLIGMGLDATPAYVTLATL
MAPALIQMGVQDIAAHLFVVYWGLASFFTPPTCIAIFVTAPMAGASVWAAGWQAVRLGIAAFLVPMSFALNPALLMEGAV
REIILATGTALVGAVALSAGLRGFALQRLSGAERALISLGGVLLIAPGIAPALIGLGLVVGVVVWSTWLQSVRPVREGSP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4666

COG function: function code R; TRAP-type uncharacterized transport system, fused permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 67612; Mature: 67481

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQAKPVVPPILLVLTTLTVLWHVVTIAQLPTWFGIFIPQASIRATSLVLAAVLILLTS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
HAASGHEGEPLKDGVRFRWLDLLVFAPLAAGCSLVIFNYDKVLDYGFFGALDTTGVILAL
CCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCHHHHHHHHHHH
CVAVPLLELVRRKTGIVLPIIILSFVAIAMFQAYLPGVLHGRGYSLDRLRYSSYVGESGI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCC
FGAPLGIAVNIVMVYLLFGALMERAGASRWFMDLALSLTGRSSGGPAKASVVASAMFGSI
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
SGSPSGNAATTGVFTIPMMREVGYKPSFAAAVEAVASTGGMILPPVMGAIAFLMAEWIGR
CCCCCCCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHH
TYREVVIAALIPAILYFIVIFASVHFEAKRSGIRAMARTDLPAFWKTLRSGWYYALPMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
LIWFLIIAALPPGMAGIYCCGVVLLCSFLSPDRSRWLLPRPLLLAMKDAVMRWLVIVVIT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ASVGIMIGAMELSGVGLNVSRFIVDIGGGNLVVTLVLVGAVSLLIGMGLDATPAYVTLAT
HHHHHHEEHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LMAPALIQMGVQDIAAHLFVVYWGLASFFTPPTCIAIFVTAPMAGASVWAAGWQAVRLGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAFLVPMSFALNPALLMEGAVREIILATGTALVGAVALSAGLRGFALQRLSGAERALISL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHH
GGVLLIAPGIAPALIGLGLVVGVVVWSTWLQSVRPVREGSP
CCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSQAKPVVPPILLVLTTLTVLWHVVTIAQLPTWFGIFIPQASIRATSLVLAAVLILLTS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH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CCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]