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The map label for this gene is proA [H]

Identifier: 110633417

GI number: 110633417

Start: 1166972

End: 1167736

Strand: Reverse

Name: proA [H]

Synonym: Meso_1063

Alternate gene names: 110633417

Gene position: 1167736-1166972 (Counterclockwise)

Preceding gene: 110633418

Following gene: 110633416

Centisome position: 26.46

GC content: 63.4

Gene sequence:

>765_bases
ATGTCTGACCGCCGCCTGACCGGCAAAATCCATCCGTCCGGGATCGGAGCAATCGAGCTGCCGAAAGTCCCCGCGGATAT
TCTGGAAGGATTTCGCGCACTTGGCGCGGATGCTTCGAGCGTGGTCTCTGACGCGATGGACGAAATGGGCGTGGCGAAGG
CCATCGGCGCATCGGTGCTTCGCCCCATCTATGCGCCCGCCGCGATCGTCGGCCGCGCGCTCACGCTGCGCAACGTGGTC
CAGGAGGACAGCCCCTACAAAGGAGCCTCGGAAAAGATCTCCCGCCTGGCGGAGATTGAGGCCCATAATCTCGCCGAGCC
GGGAGACGTGCTCGTCATCGAAGGCGTGCATGGTGTTTCGAATATCGGCGGCATCTCCGCGGCAATCGGCAAGCGGCAGG
GCGAGATCGGCGCGATCGTGGACGGCGGCGTGCGCGATGTGGGCGATTGCCGCTCCCTCGGGTATCCGATGTGGAGCCGC
GACGTGACCCCGCTCACCGGGAAATGGCGCATCCAGACCGTACAGATTAATTTCCCGGTGCAGATCGCCGGCGTGCAGGT
CACGCCGGGCGACATTGTCATTGCCGACGAAACGGGCATCTGTTTCATTCCGCCGGATAAAGCTGCCGCGGTGCTGAAAC
GCTGCCAGGAAATCATGGCGGCCGAGGCAAGCCGGCACAAGGATATCTCCGCCGGCGTTCCTGTTCCCGATCTTGCCAAT
CGCGCCGGCGCCTTCACCATGCCCACACAGGACAAGCAGAAATGA

Upstream 100 bases:

>100_bases
CCGAACGGCGGGGCGCAGCGCGGCGCGGGCAGCGCTTGCGCGCGGCGAGAAGGTCCGCTCCACTGCGCTTTGACGAACCC
CGAGAAGACGAAGGTGCACA

Downstream 100 bases:

>100_bases
ACATGGATCAATATCAGGGCGCCCAGGGAACGAAAGAACGCACGGGCGCGCAGGTGCTGATCGATTCACTTATCGCTCAA
GGGGCAGACCTTGCCTTCTG

Product: demethylmenaquinone methyltransferase-like

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSDRRLTGKIHPSGIGAIELPKVPADILEGFRALGADASSVVSDAMDEMGVAKAIGASVLRPIYAPAAIVGRALTLRNVV
QEDSPYKGASEKISRLAEIEAHNLAEPGDVLVIEGVHGVSNIGGISAAIGKRQGEIGAIVDGGVRDVGDCRSLGYPMWSR
DVTPLTGKWRIQTVQINFPVQIAGVQVTPGDIVIADETGICFIPPDKAAAVLKRCQEIMAAEASRHKDISAGVPVPDLAN
RAGAFTMPTQDKQK

Sequences:

>Translated_254_residues
MSDRRLTGKIHPSGIGAIELPKVPADILEGFRALGADASSVVSDAMDEMGVAKAIGASVLRPIYAPAAIVGRALTLRNVV
QEDSPYKGASEKISRLAEIEAHNLAEPGDVLVIEGVHGVSNIGGISAAIGKRQGEIGAIVDGGVRDVGDCRSLGYPMWSR
DVTPLTGKWRIQTVQINFPVQIAGVQVTPGDIVIADETGICFIPPDKAAAVLKRCQEIMAAEASRHKDISAGVPVPDLAN
RAGAFTMPTQDKQK
>Mature_253_residues
SDRRLTGKIHPSGIGAIELPKVPADILEGFRALGADASSVVSDAMDEMGVAKAIGASVLRPIYAPAAIVGRALTLRNVVQ
EDSPYKGASEKISRLAEIEAHNLAEPGDVLVIEGVHGVSNIGGISAAIGKRQGEIGAIVDGGVRDVGDCRSLGYPMWSRD
VTPLTGKWRIQTVQINFPVQIAGVQVTPGDIVIADETGICFIPPDKAAAVLKRCQEIMAAEASRHKDISAGVPVPDLANR
AGAFTMPTQDKQK

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 26618; Mature: 26487

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRRLTGKIHPSGIGAIELPKVPADILEGFRALGADASSVVSDAMDEMGVAKAIGASVL
CCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RPIYAPAAIVGRALTLRNVVQEDSPYKGASEKISRLAEIEAHNLAEPGDVLVIEGVHGVS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
NIGGISAAIGKRQGEIGAIVDGGVRDVGDCRSLGYPMWSRDVTPLTGKWRIQTVQINFPV
CCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCE
QIAGVQVTPGDIVIADETGICFIPPDKAAAVLKRCQEIMAAEASRHKDISAGVPVPDLAN
EEEEEEECCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
RAGAFTMPTQDKQK
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SDRRLTGKIHPSGIGAIELPKVPADILEGFRALGADASSVVSDAMDEMGVAKAIGASVL
CCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RPIYAPAAIVGRALTLRNVVQEDSPYKGASEKISRLAEIEAHNLAEPGDVLVIEGVHGVS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
NIGGISAAIGKRQGEIGAIVDGGVRDVGDCRSLGYPMWSRDVTPLTGKWRIQTVQINFPV
CCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCE
QIAGVQVTPGDIVIADETGICFIPPDKAAAVLKRCQEIMAAEASRHKDISAGVPVPDLAN
EEEEEEECCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
RAGAFTMPTQDKQK
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]