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The map label for this gene is nuoC

Identifier: 110633378

GI number: 110633378

Start: 1124448

End: 1125050

Strand: Direct

Name: nuoC

Synonym: Meso_1024

Alternate gene names: 110633378

Gene position: 1124448-1125050 (Clockwise)

Preceding gene: 110633377

Following gene: 110633379

Centisome position: 25.48

GC content: 56.72

Gene sequence:

>603_bases
ATGAATGAAGCGCTGAGGGATCTCGCGGGCTACATCAAGGAAAAGCTGGACGGCCGGGTCCAGGACTGGATGGTCGCCTA
TGACGAGCTGACGATTTTCGTCGAGCCAGGCGATATCGTCGATGTCCTGACTTTCCTGAAGAGCGACGTGCAGTGCCAGT
TCTTCGCCTTTGTCGATATTTCGGGCGTGGATTATCCGGCACGTGAGAGGCGCTTCGAGGTTGTCTATCACCTGCTCTCG
CCGCGGCAGAACCAACGCATCCGCGTCAAGGTCTCGACCGACGAGGAAACGCCGATCCCCTCCGTGATCGAGGTTTTCCC
GGCCGCGAACTGGTATGAGCGCGAGATCTATGATCTTTACGGCGTGCTTTTCACAGAGCACCCGGACCTGCGCCGTATTC
TCACGGACTATGGCTTCGAGGGGCATCCGCTCAGGAAGGACTTCCCGCTCACGGGCTTTGTCGAGGTGCATTATGACGAC
GAGGCCAAGCGGGTCGTCTACCAACCGGTGAATCTGCGGCAGGAATTCAGAAATTTCGACTTTTTGTCTCCATGGGAGGG
AACCGATTACGTCCTTCCTGGCGATGAAAAAGCAAAGCAGTGA

Upstream 100 bases:

>100_bases
GCCCGGCTGCCCGCCCACCGCGGAAGCGCTGCTATACGGCATTCTTCTCCTTCAAAAGAAGATCCGCCGGACCGGCACCA
TCGAGCGCTAGGAGCGGACC

Downstream 100 bases:

>100_bases
TCGGGAAGGTGTCGCGTGGCTGAAACCTCCATCCGCAACTTCAATATCAATTTCGGCCCGCAGCATCCGGCCGCGCACGG
CGTGCTTCGTCTTGTTCTGG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MNEALRDLAGYIKEKLDGRVQDWMVAYDELTIFVEPGDIVDVLTFLKSDVQCQFFAFVDISGVDYPARERRFEVVYHLLS
PRQNQRIRVKVSTDEETPIPSVIEVFPAANWYEREIYDLYGVLFTEHPDLRRILTDYGFEGHPLRKDFPLTGFVEVHYDD
EAKRVVYQPVNLRQEFRNFDFLSPWEGTDYVLPGDEKAKQ

Sequences:

>Translated_200_residues
MNEALRDLAGYIKEKLDGRVQDWMVAYDELTIFVEPGDIVDVLTFLKSDVQCQFFAFVDISGVDYPARERRFEVVYHLLS
PRQNQRIRVKVSTDEETPIPSVIEVFPAANWYEREIYDLYGVLFTEHPDLRRILTDYGFEGHPLRKDFPLTGFVEVHYDD
EAKRVVYQPVNLRQEFRNFDFLSPWEGTDYVLPGDEKAKQ
>Mature_200_residues
MNEALRDLAGYIKEKLDGRVQDWMVAYDELTIFVEPGDIVDVLTFLKSDVQCQFFAFVDISGVDYPARERRFEVVYHLLS
PRQNQRIRVKVSTDEETPIPSVIEVFPAANWYEREIYDLYGVLFTEHPDLRRILTDYGFEGHPLRKDFPLTGFVEVHYDD
EAKRVVYQPVNLRQEFRNFDFLSPWEGTDYVLPGDEKAKQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=187, Percent_Identity=57.2192513368984, Blast_Score=220, Evalue=8e-58,
Organism=Escherichia coli, GI145693162, Length=168, Percent_Identity=32.1428571428571, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=53.5135135135135, Blast_Score=200, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=53.5135135135135, Blast_Score=199, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=60.655737704918, Blast_Score=222, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_MESSB (Q11JK4)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673586.1
- ProteinModelPortal:   Q11JK4
- SMR:   Q11JK4
- STRING:   Q11JK4
- GeneID:   4180382
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1024
- NMPDR:   fig|266779.1.peg.2557
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   MSP266779:MESO_1024-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23552; Mature: 23552

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEALRDLAGYIKEKLDGRVQDWMVAYDELTIFVEPGDIVDVLTFLKSDVQCQFFAFVDI
CCHHHHHHHHHHHHHHCCHHHHHEEEEEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEE
SGVDYPARERRFEVVYHLLSPRQNQRIRVKVSTDEETPIPSVIEVFPAANWYEREIYDLY
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHH
GVLFTEHPDLRRILTDYGFEGHPLRKDFPLTGFVEVHYDDEAKRVVYQPVNLRQEFRNFD
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCHHHHHHHCCC
FLSPWEGTDYVLPGDEKAKQ
CCCCCCCCCEEECCCHHCCC
>Mature Secondary Structure
MNEALRDLAGYIKEKLDGRVQDWMVAYDELTIFVEPGDIVDVLTFLKSDVQCQFFAFVDI
CCHHHHHHHHHHHHHHCCHHHHHEEEEEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEE
SGVDYPARERRFEVVYHLLSPRQNQRIRVKVSTDEETPIPSVIEVFPAANWYEREIYDLY
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHH
GVLFTEHPDLRRILTDYGFEGHPLRKDFPLTGFVEVHYDDEAKRVVYQPVNLRQEFRNFD
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCHHHHHHHCCC
FLSPWEGTDYVLPGDEKAKQ
CCCCCCCCCEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA