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The map label for this gene is gsiC [H]

Identifier: 110633352

GI number: 110633352

Start: 1095218

End: 1096144

Strand: Reverse

Name: gsiC [H]

Synonym: Meso_0998

Alternate gene names: 110633352

Gene position: 1096144-1095218 (Counterclockwise)

Preceding gene: 110633353

Following gene: 110633351

Centisome position: 24.84

GC content: 63.32

Gene sequence:

>927_bases
ATGGTTCAGTTCGTCCTCACGAGGCTCCTCCGGGCTGTCATCACGATTGCCGCCGTCGTCACCTTCGCATTTGTCGTGCT
GCGCATGTCGGGCGATCCGGCACAGGTGATGCTCGGCCCCGACGTGCCGCAGGAGTCGGTCGACGCTTTCCGCCGCGCCT
GGGGGCTCGATCAGCCGCTCTGGGTACAATACTTCGCCTATCTCAAATCGATCCTCACAGGCGATTTCGGCGTCTCGATG
CGCGACAAGGCCCCAGCCATCCAACTGGTGCTGGAACGCGTGCCTGCCACGCTGCAGCTGACGCTTCCAGCCCTCTTCCT
GAAGCTCCTGATTGGCATTCCGGCCGGCGTCTATGCCGCCCTGCACCGGCAGAGCGTCACGGATCGCGGCGTGATCCTGG
CTTCGATCATCGGCTTCACGATACCGTCCTTCGTGTTGGGGTTGCTCCTCGTGCTGATCTTCTCGGTGACGTTCGGCGTG
CTGCCGTCAGGAGGACAGGACACCTGGATGCACGGCATCCTCCCGACGCTTACCTTGAGCATCGGCGGCATCGGCATTCT
CGCCCGCTTTTCGCGTAGCGCCATGATCGAGGTGATGGGCCAGCCATTCATCCGCACGGCTTCGGCCAAGGGCCTGAAAT
GGCGCGAGGTCGTCTGGGGGCACGCGCTGCCCAATGCCGCGATCCCGATCGTCACGATAGTGGGCTTCATGGTTGGTTCG
CTCATCGCCGGCGCCGTGGTGGTGGAATCGATCTTCTCATGGCCGGGGATCGGCAGGCTGCTGGTCGTATCTGTCACGAA
CCGCGACCTCGCCGTCGTGCAGTGTATCCTCCTCATCATCGCAGCCGCCATGGTGATTTCCAACCTGGTTGTGGACCTCC
TCTACGGCTGGCTCGACCCGCGACTGCGCGCGCATGTCGCGCATTAG

Upstream 100 bases:

>100_bases
CGCACCAGAACGCCTGAGCTGCGCCGGATCGAGACGGGCCGCACGGCCGCCTGCCACCTCTTGGCGAATGACCTCGCCGT
GGCAGCCTAAGGAAACAGAA

Downstream 100 bases:

>100_bases
GTAACAGGAAGAAGGCATGTCCTCGGCAGATCTGACCCAAACGCAACAGACGCCACGCCCGGCTTTCGGCATTCTGGCCC
GCATTCGCCGTCAGGTGCCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MVQFVLTRLLRAVITIAAVVTFAFVVLRMSGDPAQVMLGPDVPQESVDAFRRAWGLDQPLWVQYFAYLKSILTGDFGVSM
RDKAPAIQLVLERVPATLQLTLPALFLKLLIGIPAGVYAALHRQSVTDRGVILASIIGFTIPSFVLGLLLVLIFSVTFGV
LPSGGQDTWMHGILPTLTLSIGGIGILARFSRSAMIEVMGQPFIRTASAKGLKWREVVWGHALPNAAIPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLVVSVTNRDLAVVQCILLIIAAAMVISNLVVDLLYGWLDPRLRAHVAH

Sequences:

>Translated_308_residues
MVQFVLTRLLRAVITIAAVVTFAFVVLRMSGDPAQVMLGPDVPQESVDAFRRAWGLDQPLWVQYFAYLKSILTGDFGVSM
RDKAPAIQLVLERVPATLQLTLPALFLKLLIGIPAGVYAALHRQSVTDRGVILASIIGFTIPSFVLGLLLVLIFSVTFGV
LPSGGQDTWMHGILPTLTLSIGGIGILARFSRSAMIEVMGQPFIRTASAKGLKWREVVWGHALPNAAIPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLVVSVTNRDLAVVQCILLIIAAAMVISNLVVDLLYGWLDPRLRAHVAH
>Mature_308_residues
MVQFVLTRLLRAVITIAAVVTFAFVVLRMSGDPAQVMLGPDVPQESVDAFRRAWGLDQPLWVQYFAYLKSILTGDFGVSM
RDKAPAIQLVLERVPATLQLTLPALFLKLLIGIPAGVYAALHRQSVTDRGVILASIIGFTIPSFVLGLLLVLIFSVTFGV
LPSGGQDTWMHGILPTLTLSIGGIGILARFSRSAMIEVMGQPFIRTASAKGLKWREVVWGHALPNAAIPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLVVSVTNRDLAVVQCILLIIAAAMVISNLVVDLLYGWLDPRLRAHVAH

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=304, Percent_Identity=39.4736842105263, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1789888, Length=310, Percent_Identity=39.6774193548387, Blast_Score=217, Evalue=6e-58,
Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=36.2017804154303, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1787497, Length=310, Percent_Identity=36.7741935483871, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787761, Length=325, Percent_Identity=37.5384615384615, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=29.0441176470588, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788504, Length=284, Percent_Identity=27.112676056338, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33223; Mature: 33223

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFVLTRLLRAVITIAAVVTFAFVVLRMSGDPAQVMLGPDVPQESVDAFRRAWGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHH
WVQYFAYLKSILTGDFGVSMRDKAPAIQLVLERVPATLQLTLPALFLKLLIGIPAGVYAA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCHHHHHH
LHRQSVTDRGVILASIIGFTIPSFVLGLLLVLIFSVTFGVLPSGGQDTWMHGILPTLTLS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IGGIGILARFSRSAMIEVMGQPFIRTASAKGLKWREVVWGHALPNAAIPIVTIVGFMVGS
HCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
LIAGAVVVESIFSWPGIGRLLVVSVTNRDLAVVQCILLIIAAAMVISNLVVDLLYGWLDP
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
RLRAHVAH
HHHHHCCC
>Mature Secondary Structure
MVQFVLTRLLRAVITIAAVVTFAFVVLRMSGDPAQVMLGPDVPQESVDAFRRAWGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHH
WVQYFAYLKSILTGDFGVSMRDKAPAIQLVLERVPATLQLTLPALFLKLLIGIPAGVYAA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCHHHHHH
LHRQSVTDRGVILASIIGFTIPSFVLGLLLVLIFSVTFGVLPSGGQDTWMHGILPTLTLS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IGGIGILARFSRSAMIEVMGQPFIRTASAKGLKWREVVWGHALPNAAIPIVTIVGFMVGS
HCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
LIAGAVVVESIFSWPGIGRLLVVSVTNRDLAVVQCILLIIAAAMVISNLVVDLLYGWLDP
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
RLRAHVAH
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA