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The map label for this gene is alr [H]

Identifier: 110633340

GI number: 110633340

Start: 1081856

End: 1083025

Strand: Reverse

Name: alr [H]

Synonym: Meso_0986

Alternate gene names: 110633340

Gene position: 1083025-1081856 (Counterclockwise)

Preceding gene: 110633341

Following gene: 110633339

Centisome position: 24.54

GC content: 62.91

Gene sequence:

>1170_bases
GTGCCTGTTCCGTCGCATATATCGGATACAGGCCCGCCGCCTCATCTGGCGGGCGGGCGACTGACGGTCGACCTTTCCGC
GCTTGTGGCGAATTACCAGCTTCTTGCCCGGCGGTCCGCGCCCGCCGGAGCGGCGGCGGTCCTGAAGGCAGACGCCTATG
GGCTGGGGCTGAAACCTGTTGGCTCGGCGCTTTGGGCAGCCGGGTGCCGCCGCTTTTTCGTGGCGCTGCCGCAGGAAGGA
ATTGAGCTGCGCGCCATCCTTCCCGAGGCGGAGATCTTCGTTCTTACCGGCCTTTTCGCCGTTGAATCAGCCGCAGCCTA
TCGCGAGGCTCGACTGATCCCGGTCCTTAACTCCCAAAGCGACATCTCCATTTGGGAAGCACATGGCTGGAATGATCAGC
GTTCTCGCCCCTGCGCTGTTCATGTCGACACCGGCATGAACCGGCTTGGCCTTACCCCCGAACGGGCGCGCTCGCTCGCG
GAGGAGAACGCGCTGACCGGCGCCCTTACCCCCATCCTGCTGATGAGCCATCTTGCTTGCGCGGATACTCCCGACCACCC
GCTGAACCGTCGGCAACTCGAATTGTTTCAAGCAGTTCGGACGCTTTTCCCACAAAGCGAATCAAGTCTCTGCAACTCCG
CAGGCATCTTTCTCGGGAGCGATTTCCTTTGCGATCTCACCCGCCCCGGTATCGCTCTTTATGGAGGCGCGCCCGTGAAA
GGCATCGCAAATCCGATGCGAGCGGTGGCGACGGTGGAGGCCCGTGTGGTTCAGGTTCGGCACGTGCGCGCGGGGGAGAC
GGTGAGCTATGGGGCGACGCCGCTTGCGCGCGATAGCGTCATCGCCGTTTGTTCGGCAGGCTATGCGGATGGATACCACC
TCGCCGGCTCCGGCGACAGGGTGCCGCTCAGGCGTGCCGTCCGCAAAGCTGCCGAAGGCTTCATTCACGGGCGCCGCGTG
CCGGTGGTCGGTCGCGTCACTATGGATCTCACGCTGTTCGACGTTACTGAAGTCGGCATGGATGTTATTGCGCCGGGCGA
TCACATCGAGCTTTTCGGACCGAATATGCCGATCGATGAGGTGGCCGAAGCGGCAGGTACGATCGCCTACGAGCTGCTGA
CCTCGCTGGGACGGAGATATTATCGCGAATATGTCGGAGGGGTCGTGTGA

Upstream 100 bases:

>100_bases
ACGGGCCTACGGGAATGGTGCCCCTTGGCTTCCAGGGCGAGTTCACGCGCTTCTTCGACCTTGCGGAGGATTCGCACCTG
CCGGAGCGTTTCGAATAGCG

Downstream 100 bases:

>100_bases
CGGCAATCCTCATATCCTGCTCCCCGCACGCTCTCCTCTGGGCTAGGACCAGGGCCAGCCGCCGGATGGTCAGCAAATAA
TGGCCAAATCTCGCTTTCAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MPVPSHISDTGPPPHLAGGRLTVDLSALVANYQLLARRSAPAGAAAVLKADAYGLGLKPVGSALWAAGCRRFFVALPQEG
IELRAILPEAEIFVLTGLFAVESAAAYREARLIPVLNSQSDISIWEAHGWNDQRSRPCAVHVDTGMNRLGLTPERARSLA
EENALTGALTPILLMSHLACADTPDHPLNRRQLELFQAVRTLFPQSESSLCNSAGIFLGSDFLCDLTRPGIALYGGAPVK
GIANPMRAVATVEARVVQVRHVRAGETVSYGATPLARDSVIAVCSAGYADGYHLAGSGDRVPLRRAVRKAAEGFIHGRRV
PVVGRVTMDLTLFDVTEVGMDVIAPGDHIELFGPNMPIDEVAEAAGTIAYELLTSLGRRYYREYVGGVV

Sequences:

>Translated_389_residues
MPVPSHISDTGPPPHLAGGRLTVDLSALVANYQLLARRSAPAGAAAVLKADAYGLGLKPVGSALWAAGCRRFFVALPQEG
IELRAILPEAEIFVLTGLFAVESAAAYREARLIPVLNSQSDISIWEAHGWNDQRSRPCAVHVDTGMNRLGLTPERARSLA
EENALTGALTPILLMSHLACADTPDHPLNRRQLELFQAVRTLFPQSESSLCNSAGIFLGSDFLCDLTRPGIALYGGAPVK
GIANPMRAVATVEARVVQVRHVRAGETVSYGATPLARDSVIAVCSAGYADGYHLAGSGDRVPLRRAVRKAAEGFIHGRRV
PVVGRVTMDLTLFDVTEVGMDVIAPGDHIELFGPNMPIDEVAEAAGTIAYELLTSLGRRYYREYVGGVV
>Mature_388_residues
PVPSHISDTGPPPHLAGGRLTVDLSALVANYQLLARRSAPAGAAAVLKADAYGLGLKPVGSALWAAGCRRFFVALPQEGI
ELRAILPEAEIFVLTGLFAVESAAAYREARLIPVLNSQSDISIWEAHGWNDQRSRPCAVHVDTGMNRLGLTPERARSLAE
ENALTGALTPILLMSHLACADTPDHPLNRRQLELFQAVRTLFPQSESSLCNSAGIFLGSDFLCDLTRPGIALYGGAPVKG
IANPMRAVATVEARVVQVRHVRAGETVSYGATPLARDSVIAVCSAGYADGYHLAGSGDRVPLRRAVRKAAEGFIHGRRVP
VVGRVTMDLTLFDVTEVGMDVIAPGDHIELFGPNMPIDEVAEAAGTIAYELLTSLGRRYYREYVGGVV

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=370, Percent_Identity=32.7027027027027, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790487, Length=373, Percent_Identity=30.2949061662198, Blast_Score=141, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41489; Mature: 41358

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPSHISDTGPPPHLAGGRLTVDLSALVANYQLLARRSAPAGAAAVLKADAYGLGLKPV
CCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHH
GSALWAAGCRRFFVALPQEGIELRAILPEAEIFVLTGLFAVESAAAYREARLIPVLNSQS
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHCEEEEEECCCC
DISIWEAHGWNDQRSRPCAVHVDTGMNRLGLTPERARSLAEENALTGALTPILLMSHLAC
CCEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ADTPDHPLNRRQLELFQAVRTLFPQSESSLCNSAGIFLGSDFLCDLTRPGIALYGGAPVK
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCEEECCCCEEECCCCCEEEECCCCCH
GIANPMRAVATVEARVVQVRHVRAGETVSYGATPLARDSVIAVCSAGYADGYHLAGSGDR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCCEEECCCCCC
VPLRRAVRKAAEGFIHGRRVPVVGRVTMDLTLFDVTEVGMDVIAPGDHIELFGPNMPIDE
CHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEHHHHCHHEECCCCEEEEECCCCCHHH
VAEAAGTIAYELLTSLGRRYYREYVGGVV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PVPSHISDTGPPPHLAGGRLTVDLSALVANYQLLARRSAPAGAAAVLKADAYGLGLKPV
CCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHH
GSALWAAGCRRFFVALPQEGIELRAILPEAEIFVLTGLFAVESAAAYREARLIPVLNSQS
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHCEEEEEECCCC
DISIWEAHGWNDQRSRPCAVHVDTGMNRLGLTPERARSLAEENALTGALTPILLMSHLAC
CCEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ADTPDHPLNRRQLELFQAVRTLFPQSESSLCNSAGIFLGSDFLCDLTRPGIALYGGAPVK
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCEEECCCCEEECCCCCEEEECCCCCH
GIANPMRAVATVEARVVQVRHVRAGETVSYGATPLARDSVIAVCSAGYADGYHLAGSGDR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCCEEECCCCCC
VPLRRAVRKAAEGFIHGRRVPVVGRVTMDLTLFDVTEVGMDVIAPGDHIELFGPNMPIDE
CHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEHHHHCHHEECCCCEEEEECCCCCHHH
VAEAAGTIAYELLTSLGRRYYREYVGGVV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]