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The map label for this gene is yajO [H]

Identifier: 110633330

GI number: 110633330

Start: 1072904

End: 1073848

Strand: Direct

Name: yajO [H]

Synonym: Meso_0976

Alternate gene names: 110633330

Gene position: 1072904-1073848 (Clockwise)

Preceding gene: 110633329

Following gene: 110633332

Centisome position: 24.32

GC content: 59.58

Gene sequence:

>945_bases
ATGAAACTTCGCAGGCTTGGACGGACGGATATTCAGATCGCTCCCCTGATCCTTGGAACCAACGTGGTTGGCTGGACCGC
GGACGAAAAGACGTCCTTCACGATTTTGGACGCCTTTGTGGCGGAGGGCTTCTCTGCGATCGATACTGCAGATTCCTATT
CGCGGTGGGTGCCGGGAAACGACAGCGACAGCGAAAAGATCATCGGGCGCTGGCTCAAGGAGCGCGGCAACCGGGACAAG
GTACATATCTTCACCAAGGTCGGCTCGGACATGGGCCAGGGCAAGAAGGACCTTTCGGCGAAGTGGATCGAGCAGGAAGT
GGACACCTCGCTCAAGCGCCTGCAGACCGACTATATCGATCTTTATCAGAGCCATTGGCCCGATCCCACCGTCACCCACG
AGGAGACGCTTTCGGCCTATGACCGGCTGATCAAGGCCGGAAAAGTCCGCTACATCGGCACCTGCAACTATGATGCGAAG
CTGCTGTCGGCGGCCTTGGCGGCATCGAAGGAAAAGGAGCTCCCACGCTACGAGACGCTGCAGAACGAGTACAATCTGTA
CACGCGCGGCCAGTACGAGGGCGAGGTTCAGGAACTGGTGCTGCGCGAAGGGCTGAGTCTCATGTCCTACTTTTCGCTAG
CTTCCGGCTTCCTCACCGGAAAATATCGTTCCGAAGCCGATTACGGCAAAAGTCCCCGTGGGAAGGGTATGGCGCGATAT
CTCGATTCCAAAGGAGTGCGCCTCCTTGAGGCGATGGACAAGGTGGCCGCAAACACCGGCGCAGCACATGCCGAGATCGC
GCTGGCCTGGATCAATGCACAGCCGGGCGTTGCCGCCCCGATTGCCTCCGCCACGTCCGTGGGGCAGCTTCAAAGCCTCA
TCCGCGGCGCGCGGCTCGCTCTCAGTGAGGACGATCTGGGATTGCTCCGCCAGGCTGGCAAATAG

Upstream 100 bases:

>100_bases
GGTGCCGGCCTACTAGAGCAATTGCAGGAAAAGTGGAAACACTAAGCGGATCTAACATCGCGTGAATACCGCCTCCCCAG
GCAATCACAGGAGACCAGAG

Downstream 100 bases:

>100_bases
GCGCCCGCCACTCCACCATTGAAAAAGAGCCGCTGTTTCCAGCGGCTCCAATCTAGCATGAGTATGCGAACGCTTGGGTC
AAGCAAAACGGAAGAAACGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKLRRLGRTDIQIAPLILGTNVVGWTADEKTSFTILDAFVAEGFSAIDTADSYSRWVPGNDSDSEKIIGRWLKERGNRDK
VHIFTKVGSDMGQGKKDLSAKWIEQEVDTSLKRLQTDYIDLYQSHWPDPTVTHEETLSAYDRLIKAGKVRYIGTCNYDAK
LLSAALAASKEKELPRYETLQNEYNLYTRGQYEGEVQELVLREGLSLMSYFSLASGFLTGKYRSEADYGKSPRGKGMARY
LDSKGVRLLEAMDKVAANTGAAHAEIALAWINAQPGVAAPIASATSVGQLQSLIRGARLALSEDDLGLLRQAGK

Sequences:

>Translated_314_residues
MKLRRLGRTDIQIAPLILGTNVVGWTADEKTSFTILDAFVAEGFSAIDTADSYSRWVPGNDSDSEKIIGRWLKERGNRDK
VHIFTKVGSDMGQGKKDLSAKWIEQEVDTSLKRLQTDYIDLYQSHWPDPTVTHEETLSAYDRLIKAGKVRYIGTCNYDAK
LLSAALAASKEKELPRYETLQNEYNLYTRGQYEGEVQELVLREGLSLMSYFSLASGFLTGKYRSEADYGKSPRGKGMARY
LDSKGVRLLEAMDKVAANTGAAHAEIALAWINAQPGVAAPIASATSVGQLQSLIRGARLALSEDDLGLLRQAGK
>Mature_314_residues
MKLRRLGRTDIQIAPLILGTNVVGWTADEKTSFTILDAFVAEGFSAIDTADSYSRWVPGNDSDSEKIIGRWLKERGNRDK
VHIFTKVGSDMGQGKKDLSAKWIEQEVDTSLKRLQTDYIDLYQSHWPDPTVTHEETLSAYDRLIKAGKVRYIGTCNYDAK
LLSAALAASKEKELPRYETLQNEYNLYTRGQYEGEVQELVLREGLSLMSYFSLASGFLTGKYRSEADYGKSPRGKGMARY
LDSKGVRLLEAMDKVAANTGAAHAEIALAWINAQPGVAAPIASATSVGQLQSLIRGARLALSEDDLGLLRQAGK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=27.1844660194175, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4504825, Length=306, Percent_Identity=27.1241830065359, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223718702, Length=220, Percent_Identity=35, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI27436971, Length=301, Percent_Identity=28.2392026578073, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436964, Length=301, Percent_Identity=26.578073089701, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI41152114, Length=220, Percent_Identity=34.5454545454545, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436962, Length=301, Percent_Identity=26.2458471760797, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436966, Length=301, Percent_Identity=26.2458471760797, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41327764, Length=220, Percent_Identity=35, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI223718708, Length=144, Percent_Identity=36.8055555555556, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI87081735, Length=318, Percent_Identity=32.7044025157233, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789199, Length=337, Percent_Identity=33.5311572700297, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788070, Length=337, Percent_Identity=29.9703264094956, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=26.0061919504644, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788081, Length=308, Percent_Identity=28.2467532467532, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786400, Length=266, Percent_Identity=27.8195488721804, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082198, Length=226, Percent_Identity=27.8761061946903, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=334, Percent_Identity=26.9461077844311, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=27.8145695364238, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=25.9475218658892, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=336, Percent_Identity=25.297619047619, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=257, Percent_Identity=25.2918287937743, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321052, Length=167, Percent_Identity=32.3353293413174, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34707; Mature: 34707

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRRLGRTDIQIAPLILGTNVVGWTADEKTSFTILDAFVAEGFSAIDTADSYSRWVPGN
CCCCCCCCCCCEEEEEEEECCEEEECCCCCCCHHHHHHHHHCCCHHHCCCHHHCCCCCCC
DSDSEKIIGRWLKERGNRDKVHIFTKVGSDMGQGKKDLSAKWIEQEVDTSLKRLQTDYID
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYQSHWPDPTVTHEETLSAYDRLIKAGKVRYIGTCNYDAKLLSAALAASKEKELPRYETL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHH
QNEYNLYTRGQYEGEVQELVLREGLSLMSYFSLASGFLTGKYRSEADYGKSPRGKGMARY
HHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
LDSKGVRLLEAMDKVAANTGAAHAEIALAWINAQPGVAAPIASATSVGQLQSLIRGARLA
HHHCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LSEDDLGLLRQAGK
CCCCCHHHHHHCCC
>Mature Secondary Structure
MKLRRLGRTDIQIAPLILGTNVVGWTADEKTSFTILDAFVAEGFSAIDTADSYSRWVPGN
CCCCCCCCCCCEEEEEEEECCEEEECCCCCCCHHHHHHHHHCCCHHHCCCHHHCCCCCCC
DSDSEKIIGRWLKERGNRDKVHIFTKVGSDMGQGKKDLSAKWIEQEVDTSLKRLQTDYID
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYQSHWPDPTVTHEETLSAYDRLIKAGKVRYIGTCNYDAKLLSAALAASKEKELPRYETL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHH
QNEYNLYTRGQYEGEVQELVLREGLSLMSYFSLASGFLTGKYRSEADYGKSPRGKGMARY
HHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
LDSKGVRLLEAMDKVAANTGAAHAEIALAWINAQPGVAAPIASATSVGQLQSLIRGARLA
HHHCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LSEDDLGLLRQAGK
CCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]