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The map label for this gene is cysS [H]

Identifier: 110633319

GI number: 110633319

Start: 1061231

End: 1062751

Strand: Direct

Name: cysS [H]

Synonym: Meso_0965

Alternate gene names: 110633319

Gene position: 1061231-1062751 (Clockwise)

Preceding gene: 110633318

Following gene: 110633320

Centisome position: 24.05

GC content: 63.25

Gene sequence:

>1521_bases
ATGGATGTTGTTATCACAGGATCGGGCATGTCTGACGGGTTCAAGGCACTGAAGCTCTACAACACGCTGACGCGGCGCGA
CGAGGAGTTCGTGCCCCTCGATCCGGCGAATGTGCGCATGTATGTCTGCGGGCCCACGGTCTACGACTTCGCCCATATCG
GCAATGCGCGACCGGTGATCGTCTTCGACGTCCTCTTCAGGCTCCTGCGCCAACTCTACGGCGATGACCACGTCACCTAT
GTCCGCAACATCACGGACGTTGATGACAAGATCAACGCCCGCGCATTGCGTGACTTCGGCGAGGACATTACCGCGGGCAG
GCTCACGCTCAACGAGGCCATCCGCCGCGTGACCGAGCGCACGGCGGCGCAATTTCATGCGGATGTGGCCGCACTCGGCT
GCCTTGCTCCTACCCATGAGCCGCGCGCGACGGAATTCGTGCTGCCGCGGACGGATGGCAAGGCCGATATGGCAAGCTTG
ATTCAAACTCTCATCGACCGCGGCCATGCCTATGCGGCCAAAGGAGAAATCCTGTTCGATACGGCCTCCATGCCGGATTA
TGGCCAGCTTTCCAAGCGCCGGCTGGAAGACCAGCAGGCAGGCGCGCGCGTGGCCGTGGACCCGCATAAGAGGAACCCGT
CGGATTTCGTTCTCTGGAAGGAATCTTCGGCCGAGGAGCCGGGCTGGGAAGGGCGCTTCACCTTCGAGGGAAAGCCGCTC
GTCATCCGCGGCCGCCCCGGCTGGCACATCGAATGCTCCGCCATGTCGGCGGCGTATCTGGGCGAGGTGTTCGATATCCA
CGGCGGCGGGCTCGACCTGATCTTCCCGCACCACGAGAACGAGATTGCCCAATCGCGCTGCGCCCATGGCACGCCGGTGA
TGGCCAATTACTGGCTGCACAACGGCTTTGTGCAGGTGGAGGGCAAGAAGATGGCCAAGTCCGAAGGCAACTTCGTCACC
ATCCACGACCTGCTGGCGACGGAGAATTTCGGCGGCCGCAAATGGCCCGGCGAGGTGCTGCGGCTCGCGATCCTCATGAC
CCATTACCGCGAGCCGCTCGACTTCTCATTGCGCAAGCTTGAGGAGGCGGAGGCTGTGCTCGACGGCTGGTACCGGGTGG
TGGGAGACGCCAAGCACCAAGAGGGCGATAGCGGCGCGGTACGGCGCGCGCTTCTTGATGATCTCGGAACGCCCGCAGCG
ATCACGGTTCTGCACGACCTGCGGGCGCAGGCGGCGAGGGGAAGCGAGGCCGCAAAGGCGGACCTTAAGGCGAATGCCGT
GCTTTTGGGATTGCTGACGCAGTCTCAGGACCAGTGGTTTTCTGGCAAGGCGGCGGATGCGGCGATTGATGAGGCGGCGG
TGGAAGAGCGCGTGGCTGCTCGCCTCTCCCTCCTTCGCGCGAAGAATTTCCCTGAGGCCGATCGCATCCGGGAGGAACTG
TCGGGCCGCGGGATCCAGCTCATGGACTATAAGGATCCCGAAACCGGCGAGCGCCGGACGAAATGGGAGGTGAAGCGGTG
A

Upstream 100 bases:

>100_bases
GGCATTTGCATTATCGGCTAGCGCTTCTCCGCTGGTCCGGTCGTTTTCGCCTTCCTTTCCCGATACGAAAAACGCCCAGG
CCAGCCGGCCGGAGCGCCGC

Downstream 100 bases:

>100_bases
GCGCGGAGCTGGCGACCCCCCTCTGCCCTGCCGGGCACGCTCTCAAGGGGCGTATGCTGGCGGAACAGCGCCCCCCTCTG
GCCTGCCGGCCATCTCCCCC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDVVITGSGMSDGFKALKLYNTLTRRDEEFVPLDPANVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRQLYGDDHVTY
VRNITDVDDKINARALRDFGEDITAGRLTLNEAIRRVTERTAAQFHADVAALGCLAPTHEPRATEFVLPRTDGKADMASL
IQTLIDRGHAYAAKGEILFDTASMPDYGQLSKRRLEDQQAGARVAVDPHKRNPSDFVLWKESSAEEPGWEGRFTFEGKPL
VIRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTPVMANYWLHNGFVQVEGKKMAKSEGNFVT
IHDLLATENFGGRKWPGEVLRLAILMTHYREPLDFSLRKLEEAEAVLDGWYRVVGDAKHQEGDSGAVRRALLDDLGTPAA
ITVLHDLRAQAARGSEAAKADLKANAVLLGLLTQSQDQWFSGKAADAAIDEAAVEERVAARLSLLRAKNFPEADRIREEL
SGRGIQLMDYKDPETGERRTKWEVKR

Sequences:

>Translated_506_residues
MDVVITGSGMSDGFKALKLYNTLTRRDEEFVPLDPANVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRQLYGDDHVTY
VRNITDVDDKINARALRDFGEDITAGRLTLNEAIRRVTERTAAQFHADVAALGCLAPTHEPRATEFVLPRTDGKADMASL
IQTLIDRGHAYAAKGEILFDTASMPDYGQLSKRRLEDQQAGARVAVDPHKRNPSDFVLWKESSAEEPGWEGRFTFEGKPL
VIRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTPVMANYWLHNGFVQVEGKKMAKSEGNFVT
IHDLLATENFGGRKWPGEVLRLAILMTHYREPLDFSLRKLEEAEAVLDGWYRVVGDAKHQEGDSGAVRRALLDDLGTPAA
ITVLHDLRAQAARGSEAAKADLKANAVLLGLLTQSQDQWFSGKAADAAIDEAAVEERVAARLSLLRAKNFPEADRIREEL
SGRGIQLMDYKDPETGERRTKWEVKR
>Mature_506_residues
MDVVITGSGMSDGFKALKLYNTLTRRDEEFVPLDPANVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRQLYGDDHVTY
VRNITDVDDKINARALRDFGEDITAGRLTLNEAIRRVTERTAAQFHADVAALGCLAPTHEPRATEFVLPRTDGKADMASL
IQTLIDRGHAYAAKGEILFDTASMPDYGQLSKRRLEDQQAGARVAVDPHKRNPSDFVLWKESSAEEPGWEGRFTFEGKPL
VIRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTPVMANYWLHNGFVQVEGKKMAKSEGNFVT
IHDLLATENFGGRKWPGEVLRLAILMTHYREPLDFSLRKLEEAEAVLDGWYRVVGDAKHQEGDSGAVRRALLDDLGTPAA
ITVLHDLRAQAARGSEAAKADLKANAVLLGLLTQSQDQWFSGKAADAAIDEAAVEERVAARLSLLRAKNFPEADRIREEL
SGRGIQLMDYKDPETGERRTKWEVKR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=459, Percent_Identity=33.1154684095861, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI10835051, Length=297, Percent_Identity=35.016835016835, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI62240992, Length=297, Percent_Identity=35.016835016835, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI21269877, Length=297, Percent_Identity=35.016835016835, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI303304987, Length=297, Percent_Identity=35.016835016835, Blast_Score=172, Evalue=6e-43,
Organism=Escherichia coli, GI1786737, Length=463, Percent_Identity=42.1166306695464, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17509795, Length=275, Percent_Identity=36, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17509797, Length=275, Percent_Identity=36, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6324082, Length=402, Percent_Identity=29.3532338308458, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI19922218, Length=528, Percent_Identity=30.4924242424242, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI19922364, Length=297, Percent_Identity=34.006734006734, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56314; Mature: 56314

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVITGSGMSDGFKALKLYNTLTRRDEEFVPLDPANVRMYVCGPTVYDFAHIGNARPVI
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCH
VFDVLFRLLRQLYGDDHVTYVRNITDVDDKINARALRDFGEDITAGRLTLNEAIRRVTER
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
TAAQFHADVAALGCLAPTHEPRATEFVLPRTDGKADMASLIQTLIDRGHAYAAKGEILFD
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCEEEE
TASMPDYGQLSKRRLEDQQAGARVAVDPHKRNPSDFVLWKESSAEEPGWEGRFTFEGKPL
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCEEEECCCEE
VIRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTPVMANYWLH
EEECCCCCEEEEHHHHHHHHHHHEEECCCCEEEEECCCCCHHHHHHCCCCCCEEEEHEEE
NGFVQVEGKKMAKSEGNFVTIHDLLATENFGGRKWPGEVLRLAILMTHYREPLDFSLRKL
CCEEEECCHHHHCCCCCEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
EEAEAVLDGWYRVVGDAKHQEGDSGAVRRALLDDLGTPAAITVLHDLRAQAARGSEAAKA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
DLKANAVLLGLLTQSQDQWFSGKAADAAIDEAAVEERVAARLSLLRAKNFPEADRIREEL
HCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SGRGIQLMDYKDPETGERRTKWEVKR
CCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDVVITGSGMSDGFKALKLYNTLTRRDEEFVPLDPANVRMYVCGPTVYDFAHIGNARPVI
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCH
VFDVLFRLLRQLYGDDHVTYVRNITDVDDKINARALRDFGEDITAGRLTLNEAIRRVTER
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
TAAQFHADVAALGCLAPTHEPRATEFVLPRTDGKADMASLIQTLIDRGHAYAAKGEILFD
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCEEEE
TASMPDYGQLSKRRLEDQQAGARVAVDPHKRNPSDFVLWKESSAEEPGWEGRFTFEGKPL
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCEEEECCCEE
VIRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTPVMANYWLH
EEECCCCCEEEEHHHHHHHHHHHEEECCCCEEEEECCCCCHHHHHHCCCCCCEEEEHEEE
NGFVQVEGKKMAKSEGNFVTIHDLLATENFGGRKWPGEVLRLAILMTHYREPLDFSLRKL
CCEEEECCHHHHCCCCCEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
EEAEAVLDGWYRVVGDAKHQEGDSGAVRRALLDDLGTPAAITVLHDLRAQAARGSEAAKA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
DLKANAVLLGLLTQSQDQWFSGKAADAAIDEAAVEERVAARLSLLRAKNFPEADRIREEL
HCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SGRGIQLMDYKDPETGERRTKWEVKR
CCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA