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The map label for this gene is hisC [H]

Identifier: 110633287

GI number: 110633287

Start: 1029918

End: 1031033

Strand: Reverse

Name: hisC [H]

Synonym: Meso_0933

Alternate gene names: 110633287

Gene position: 1031033-1029918 (Counterclockwise)

Preceding gene: 110633288

Following gene: 110633285

Centisome position: 23.37

GC content: 63.35

Gene sequence:

>1116_bases
ATGCCCGAGCGCCCTTCCCTTACCCCACTGGTTGAAAGCCTGCCCGCCACCGTTCCGTTTGTTGGCCCCGAGACGCAGGA
GCGCGCCCGCGGCAGATCTTTCCGTGCCCGCCTTGGCGCCAATGAAAACGGTTTCGGACCTTCGCTGGCTGTCGTGGCCG
CGATGCGGGAGGCAGCGCCGGAGATGTGGAAATACGGCGATCCCGAAAACCACGATCTCAAGCTGGCGCTCTCTGCTCAT
CTTCGCCTAGGGCCGCAAAACATCACAATCGGCGAAGGGATCGACGGCCTGCTCGGCCTTGCAGTCCGGCAATATGTTCG
GCCCGGCGATGCGGTGGTTACATCGCTGGGCGCCTATCCCACCTTCAACTATCATGTGGCCGGTTTCGGAGGCCGGCTCG
TCACGGTTCCTTATGAAGGGGACCGCGAAAACCTTTCAGGCCTGCTCGATGCCGCATGGCGGGAGAATGCCCGCGTGGTC
TATCTCTCCAATCCCGACAATCCCATGGGTAGCTGGTGGGGGGCCGACGAGATCGAACGCTTTATCGCGGGCCTGCCAGA
GACCACGCTCCTCATTCTGGACGAGGCCTATGGCGAGACCGCGCCGGCCTCTGCAATTCCGCCTCTCGAACCGTTACGGC
CCAATGTGCTGCGCATGCGCACCTTCTCCAAGGCTTACGGGCTGGCCGGGCTTAGATGCGGCTATGCGATCGGCGAGGCA
ACGGCCATCGGCGCTTTCGACAAGGTGCGCAATCATTTCGGCATGACGCGCATGGCCCAGGCGGCCGCGCTTGCTGCCCT
TTCCGACCAGGCACATCTGAGATGGGTGGTCGAGCAAGTGGATGTCTGCCGGCGGCGTATCTCGGCCATTGCGGAAGCGC
ATGGGCTCGTTCCCCTGCCCTCGGCCACGAATTTCGTGACGATAGACTGCGGGAGCGACGGTTCTTTCGCATCGCGCCTG
CTGAAGGCGCTTACAGACAGGGACGTTTTCGTGCGCAAGCCGATGGCGCCGGTCCTCGACCGATGCATCCGCGTCAGCGT
AGGACCGGAAGCCGAGATCGCAATATTCGAGGCAGAGCTTGGGCCTGCGCTGGAGAGGGCCCGACAAGGCGCCTGA

Upstream 100 bases:

>100_bases
AGTCGGCAGCGCCGGATCGCGGATAGCGTCCGGCGCCTGCACATGTTGCGGAGCATACTCGTGCCGGTGCATAACAGCGC
CGTAAGCCGAGAGTTTCGCG

Downstream 100 bases:

>100_bases
CAGGCAAAGCCCATGGCGCGGCGGCTCCTTCGCCGTCGCTCAGATCAAATCGTCCTCCCCGCCGGGGCCGAAGCCGCGGT
TCAGGATCTCGACAAGTTCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPERPSLTPLVESLPATVPFVGPETQERARGRSFRARLGANENGFGPSLAVVAAMREAAPEMWKYGDPENHDLKLALSAH
LRLGPQNITIGEGIDGLLGLAVRQYVRPGDAVVTSLGAYPTFNYHVAGFGGRLVTVPYEGDRENLSGLLDAAWRENARVV
YLSNPDNPMGSWWGADEIERFIAGLPETTLLILDEAYGETAPASAIPPLEPLRPNVLRMRTFSKAYGLAGLRCGYAIGEA
TAIGAFDKVRNHFGMTRMAQAAALAALSDQAHLRWVVEQVDVCRRRISAIAEAHGLVPLPSATNFVTIDCGSDGSFASRL
LKALTDRDVFVRKPMAPVLDRCIRVSVGPEAEIAIFEAELGPALERARQGA

Sequences:

>Translated_371_residues
MPERPSLTPLVESLPATVPFVGPETQERARGRSFRARLGANENGFGPSLAVVAAMREAAPEMWKYGDPENHDLKLALSAH
LRLGPQNITIGEGIDGLLGLAVRQYVRPGDAVVTSLGAYPTFNYHVAGFGGRLVTVPYEGDRENLSGLLDAAWRENARVV
YLSNPDNPMGSWWGADEIERFIAGLPETTLLILDEAYGETAPASAIPPLEPLRPNVLRMRTFSKAYGLAGLRCGYAIGEA
TAIGAFDKVRNHFGMTRMAQAAALAALSDQAHLRWVVEQVDVCRRRISAIAEAHGLVPLPSATNFVTIDCGSDGSFASRL
LKALTDRDVFVRKPMAPVLDRCIRVSVGPEAEIAIFEAELGPALERARQGA
>Mature_370_residues
PERPSLTPLVESLPATVPFVGPETQERARGRSFRARLGANENGFGPSLAVVAAMREAAPEMWKYGDPENHDLKLALSAHL
RLGPQNITIGEGIDGLLGLAVRQYVRPGDAVVTSLGAYPTFNYHVAGFGGRLVTVPYEGDRENLSGLLDAAWRENARVVY
LSNPDNPMGSWWGADEIERFIAGLPETTLLILDEAYGETAPASAIPPLEPLRPNVLRMRTFSKAYGLAGLRCGYAIGEAT
AIGAFDKVRNHFGMTRMAQAAALAALSDQAHLRWVVEQVDVCRRRISAIAEAHGLVPLPSATNFVTIDCGSDGSFASRLL
KALTDRDVFVRKPMAPVLDRCIRVSVGPEAEIAIFEAELGPALERARQGA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=325, Percent_Identity=24.9230769230769, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788722, Length=236, Percent_Identity=28.8135593220339, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40051; Mature: 39920

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERPSLTPLVESLPATVPFVGPETQERARGRSFRARLGANENGFGPSLAVVAAMREAAP
CCCCCCCCHHHHHCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
EMWKYGDPENHDLKLALSAHLRLGPQNITIGEGIDGLLGLAVRQYVRPGDAVVTSLGAYP
HHHCCCCCCCCCEEEEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCC
TFNYHVAGFGGRLVTVPYEGDRENLSGLLDAAWRENARVVYLSNPDNPMGSWWGADEIER
CCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHH
FIAGLPETTLLILDEAYGETAPASAIPPLEPLRPNVLRMRTFSKAYGLAGLRCGYAIGEA
HHHCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCHHHCCH
TAIGAFDKVRNHFGMTRMAQAAALAALSDQAHLRWVVEQVDVCRRRISAIAEAHGLVPLP
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
SATNFVTIDCGSDGSFASRLLKALTDRDVFVRKPMAPVLDRCIRVSVGPEAEIAIFEAEL
CCCCEEEEECCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHEECCCCCCEEEEEECCC
GPALERARQGA
CHHHHHHHCCC
>Mature Secondary Structure 
PERPSLTPLVESLPATVPFVGPETQERARGRSFRARLGANENGFGPSLAVVAAMREAAP
CCCCCCCHHHHHCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
EMWKYGDPENHDLKLALSAHLRLGPQNITIGEGIDGLLGLAVRQYVRPGDAVVTSLGAYP
HHHCCCCCCCCCEEEEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCC
TFNYHVAGFGGRLVTVPYEGDRENLSGLLDAAWRENARVVYLSNPDNPMGSWWGADEIER
CCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHH
FIAGLPETTLLILDEAYGETAPASAIPPLEPLRPNVLRMRTFSKAYGLAGLRCGYAIGEA
HHHCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCHHHCCH
TAIGAFDKVRNHFGMTRMAQAAALAALSDQAHLRWVVEQVDVCRRRISAIAEAHGLVPLP
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
SATNFVTIDCGSDGSFASRLLKALTDRDVFVRKPMAPVLDRCIRVSVGPEAEIAIFEAEL
CCCCEEEEECCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHEECCCCCCEEEEEECCC
GPALERARQGA
CHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA