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The map label for this gene is coxL [H]

Identifier: 110633261

GI number: 110633261

Start: 1003467

End: 1005779

Strand: Direct

Name: coxL [H]

Synonym: Meso_0907

Alternate gene names: 110633261

Gene position: 1003467-1005779 (Clockwise)

Preceding gene: 110633258

Following gene: 110633262

Centisome position: 22.74

GC content: 62.0

Gene sequence:

>2313_bases
ATGACGGTTCTCACACCGAAATTCGGCATGGGCGCTTCCGTGCTGCGCAAGGAAGATGAGAGCTTTATAACGGGCAGGGG
CCGCTACACCGATGACATCACTCCGCCCGGAACCCTTTGTGGATATGTCCTTCGTTCTTCTATGGCCAAAGCGCGCTTCA
CGGTTTCGTCCACCGAGGCGGCCCGTGCAGCTCCCGGCGTTCACCTGGTGCTCACCGGAGCCGACACGGCGCATCTGGGC
GACCTCATATCCGGCGGCATGCCTAAACAGCCCGATGGCAGCAAAGCCCCGACCCGCGATATCCCGATCCTCTGCCGCGA
TCGCGTCCAATATGTGGGCGACGCCGTTGCATTCATCGTCGCCGATACCCGTGAGCAGGCGCAGGATGCGGCGGAACTGA
TAGAGGTCGATTATGAGGACGAGGAGCCGGCGGTCGACACGGCTGCCGCGCTTCAAGACGGCGCCCCGCTCGTTTGGCCC
GAACTGGGCACAAACCAGGCATTTCTCTATCATGTCGGCGATAAGAGAAAGACCGATGCGGCCTTCGCCAGCGCCGACCG
GGTTGTAAAGATCGCCTTCATCAACAATCGCCTTGTCGCCAATTATATGGAGACACGCTCTGCCATCGCTGAATGGAAGC
CGGATGAGAATCGCTTTGTGCTGACCACCGGTTCGCAAGGCGTGCATTCCCTGCAGGAAATTCTCACCCGCGTCTTCGGC
ATCCCCACATCGCAATTGCGCGTGGTCACGCCCGATGTCGGCGGCGGTTTCGGAACCAAGGCCTTCGCCTACCGCGAATA
TGCCCTTGTCATGGAGGCGGCAAAGAGGCTCGGCCGGCCGGTCAAGTGGACCAGCGATCGCAACGAGCATTTCCTGACCG
ACAGCCAGGGCCGCGACAATGCGGTGACCGCCGAAATGGCGCTCGACCAGACAGGCCGTTTTCTTGCCATGCGCGTGGAG
CTGCTCGCCAATATGGGAGCGTATATCCATCAGTTCGGGCCTTATATTCCGGTCGGCGGCGCCTCGATGACCACCGGTGT
CTATGACATTCAGGCGATCGACGTGACCGTGAGAGGCGTCTACACCAACACGGCTCCGGTAGATGCCTATCGCGGGGCAG
GGCGGCCCGAGGCGGCCTTCCTCATCGAAAAGCTGGTGGAGGTATGCGCGCGCCAGATGAAGCTGCCGCGGGAAGAGATC
CGCCGGCGCAATTTCATCGGGGTGGAGCAGTTCCCCTACCGCACGCCGACGGGGCGGCGCTACGATCGCTGTGAGTTCGA
TGGGCACATGACGCTTGCGATGGAGCGCGCGGGATGGGCCACATTCGAGGAGAGATTCGCGGAGGCGAAGAAGCGCGGGC
GCATCCGTGGCATCGGCATGTCGACCTATATCGAGGCATGTGCCTTCGCCGGCTCGGAGCCCGCTTACCTCACCCTCAAC
GGCGACGGCTCGGTGACGCTTGCGATCGGCACGCAATCCAACGGGCAAGGCCATGCGACCGCCTATGCCCAGTTTGTGGC
CGAAAAGCTGAACCTAGAAATTGCGAAGATCCACGTCCATCAGGGCGATACGGATGTGCTGAAGACGGGCGGCGGAACGG
GCGGTTCGCGCTCGATCCCACTGGGTGGGGTCTCAGCGGCACGGGCGGGTGAAGATCTTGCCGAAAAAATCAAGAGGATC
GCGGCGGAGGAAATGGAAGCTTCGCCCGCCGATATCGAGCTGGTCGATGGCATCGCCAGAATCGTCGGCACCGACCGGAT
GATGGACTTCGCCTCGATCGCCAGGGCCGCGAAAAGCCCGGAAGACCTGAAGGGCTTCGGCAATTTCGAACAGCCCGAGC
CAACCTATCCGAATGGAACGCATATCTGTGAGGTCGAGATAGACCCGGCGACGGGAAGGACGGACGTCGTTGCCTATACG
ATCGTGGATGATTTCGGAGCGACGGCAAATCCGATTCTCCTGGCCGGTCAGGTTCACGGGGGCGTAGCCCAGGGTGTCGG
GCAGGCTCTGTCCGAGGAGGTGATCTATTCGGAGGACGGGCAGCTCGTGACAGCCACCTTTATGGATTATTCGATGCCGC
GTGCCGATCTGTTGCCCTTCATCCAGTTCGAGACCCGCAATGTGCCGTCCAGCACGAATGCGTTGGGGATGAAGGGTGCG
GGCGAGGCAGGCACGGTCGGCTCCACGCCGGCCGCCCTGAACGCCGTTGTCGACGCGCTTTACCGTGCCTACGGCATCTC
GCATATCGAGATGCCGGCGACGCCGGCGCGCATCTGGCAGGCGATCGCCAGCGCGAGTGCTGAGCAAGCATAA

Upstream 100 bases:

>100_bases
CCAAGAATTTCGAAGCTGGCTCTTTACACGATGCAGCCCGTCGACAAAACTGCTCAGGCCACTACGTTCAGACTTTCCAT
TCACTCGCAAGGAATTCGTT

Downstream 100 bases:

>100_bases
TTTCACTCAGGCCCGGCTGATCGTGTTGGCCGGGCGTTTTGATTCCTCCTTTTTCTGATCCGGTAAAACCATGACCGTCG
CTGCGAGCGATTTTGGCACT

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MTVLTPKFGMGASVLRKEDESFITGRGRYTDDITPPGTLCGYVLRSSMAKARFTVSSTEAARAAPGVHLVLTGADTAHLG
DLISGGMPKQPDGSKAPTRDIPILCRDRVQYVGDAVAFIVADTREQAQDAAELIEVDYEDEEPAVDTAAALQDGAPLVWP
ELGTNQAFLYHVGDKRKTDAAFASADRVVKIAFINNRLVANYMETRSAIAEWKPDENRFVLTTGSQGVHSLQEILTRVFG
IPTSQLRVVTPDVGGGFGTKAFAYREYALVMEAAKRLGRPVKWTSDRNEHFLTDSQGRDNAVTAEMALDQTGRFLAMRVE
LLANMGAYIHQFGPYIPVGGASMTTGVYDIQAIDVTVRGVYTNTAPVDAYRGAGRPEAAFLIEKLVEVCARQMKLPREEI
RRRNFIGVEQFPYRTPTGRRYDRCEFDGHMTLAMERAGWATFEERFAEAKKRGRIRGIGMSTYIEACAFAGSEPAYLTLN
GDGSVTLAIGTQSNGQGHATAYAQFVAEKLNLEIAKIHVHQGDTDVLKTGGGTGGSRSIPLGGVSAARAGEDLAEKIKRI
AAEEMEASPADIELVDGIARIVGTDRMMDFASIARAAKSPEDLKGFGNFEQPEPTYPNGTHICEVEIDPATGRTDVVAYT
IVDDFGATANPILLAGQVHGGVAQGVGQALSEEVIYSEDGQLVTATFMDYSMPRADLLPFIQFETRNVPSSTNALGMKGA
GEAGTVGSTPAALNAVVDALYRAYGISHIEMPATPARIWQAIASASAEQA

Sequences:

>Translated_770_residues
MTVLTPKFGMGASVLRKEDESFITGRGRYTDDITPPGTLCGYVLRSSMAKARFTVSSTEAARAAPGVHLVLTGADTAHLG
DLISGGMPKQPDGSKAPTRDIPILCRDRVQYVGDAVAFIVADTREQAQDAAELIEVDYEDEEPAVDTAAALQDGAPLVWP
ELGTNQAFLYHVGDKRKTDAAFASADRVVKIAFINNRLVANYMETRSAIAEWKPDENRFVLTTGSQGVHSLQEILTRVFG
IPTSQLRVVTPDVGGGFGTKAFAYREYALVMEAAKRLGRPVKWTSDRNEHFLTDSQGRDNAVTAEMALDQTGRFLAMRVE
LLANMGAYIHQFGPYIPVGGASMTTGVYDIQAIDVTVRGVYTNTAPVDAYRGAGRPEAAFLIEKLVEVCARQMKLPREEI
RRRNFIGVEQFPYRTPTGRRYDRCEFDGHMTLAMERAGWATFEERFAEAKKRGRIRGIGMSTYIEACAFAGSEPAYLTLN
GDGSVTLAIGTQSNGQGHATAYAQFVAEKLNLEIAKIHVHQGDTDVLKTGGGTGGSRSIPLGGVSAARAGEDLAEKIKRI
AAEEMEASPADIELVDGIARIVGTDRMMDFASIARAAKSPEDLKGFGNFEQPEPTYPNGTHICEVEIDPATGRTDVVAYT
IVDDFGATANPILLAGQVHGGVAQGVGQALSEEVIYSEDGQLVTATFMDYSMPRADLLPFIQFETRNVPSSTNALGMKGA
GEAGTVGSTPAALNAVVDALYRAYGISHIEMPATPARIWQAIASASAEQA
>Mature_769_residues
TVLTPKFGMGASVLRKEDESFITGRGRYTDDITPPGTLCGYVLRSSMAKARFTVSSTEAARAAPGVHLVLTGADTAHLGD
LISGGMPKQPDGSKAPTRDIPILCRDRVQYVGDAVAFIVADTREQAQDAAELIEVDYEDEEPAVDTAAALQDGAPLVWPE
LGTNQAFLYHVGDKRKTDAAFASADRVVKIAFINNRLVANYMETRSAIAEWKPDENRFVLTTGSQGVHSLQEILTRVFGI
PTSQLRVVTPDVGGGFGTKAFAYREYALVMEAAKRLGRPVKWTSDRNEHFLTDSQGRDNAVTAEMALDQTGRFLAMRVEL
LANMGAYIHQFGPYIPVGGASMTTGVYDIQAIDVTVRGVYTNTAPVDAYRGAGRPEAAFLIEKLVEVCARQMKLPREEIR
RRNFIGVEQFPYRTPTGRRYDRCEFDGHMTLAMERAGWATFEERFAEAKKRGRIRGIGMSTYIEACAFAGSEPAYLTLNG
DGSVTLAIGTQSNGQGHATAYAQFVAEKLNLEIAKIHVHQGDTDVLKTGGGTGGSRSIPLGGVSAARAGEDLAEKIKRIA
AEEMEASPADIELVDGIARIVGTDRMMDFASIARAAKSPEDLKGFGNFEQPEPTYPNGTHICEVEIDPATGRTDVVAYTI
VDDFGATANPILLAGQVHGGVAQGVGQALSEEVIYSEDGQLVTATFMDYSMPRADLLPFIQFETRNVPSSTNALGMKGAG
EAGTVGSTPAALNAVVDALYRAYGISHIEMPATPARIWQAIASASAEQA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=765, Percent_Identity=26.0130718954248, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI71773480, Length=778, Percent_Identity=23.9074550128535, Blast_Score=151, Evalue=3e-36,
Organism=Escherichia coli, GI1789230, Length=768, Percent_Identity=28.125, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1789246, Length=808, Percent_Identity=25.4950495049505, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1786478, Length=741, Percent_Identity=24.9662618083671, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=705, Percent_Identity=26.0992907801418, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17539860, Length=749, Percent_Identity=24.1655540720961, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32566215, Length=559, Percent_Identity=25.4025044722719, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17737937, Length=768, Percent_Identity=24.8697916666667, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647199, Length=651, Percent_Identity=22.273425499232, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647201, Length=718, Percent_Identity=22.1448467966574, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82835; Mature: 82704

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLTPKFGMGASVLRKEDESFITGRGRYTDDITPPGTLCGYVLRSSMAKARFTVSSTEA
CCEECCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCHH
ARAAPGVHLVLTGADTAHLGDLISGGMPKQPDGSKAPTRDIPILCRDRVQYVGDAVAFIV
HHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEE
ADTREQAQDAAELIEVDYEDEEPAVDTAAALQDGAPLVWPELGTNQAFLYHVGDKRKTDA
ECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEECCCCCCCCEEEEECCCCCCCHH
AFASADRVVKIAFINNRLVANYMETRSAIAEWKPDENRFVLTTGSQGVHSLQEILTRVFG
HHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHC
IPTSQLRVVTPDVGGGFGTKAFAYREYALVMEAAKRLGRPVKWTSDRNEHFLTDSQGRDN
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCCCCCC
AVTAEMALDQTGRFLAMRVELLANMGAYIHQFGPYIPVGGASMTTGVYDIQAIDVTVRGV
CEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEEEE
YTNTAPVDAYRGAGRPEAAFLIEKLVEVCARQMKLPREEIRRRNFIGVEQFPYRTPTGRR
EECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHCCCCCCCCCC
YDRCEFDGHMTLAMERAGWATFEERFAEAKKRGRIRGIGMSTYIEACAFAGSEPAYLTLN
CCCEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCCEEEEEC
GDGSVTLAIGTQSNGQGHATAYAQFVAEKLNLEIAKIHVHQGDTDVLKTGGGTGGSRSIP
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCHHEECCCCCCCCCCCC
LGGVSAARAGEDLAEKIKRIAAEEMEASPADIELVDGIARIVGTDRMMDFASIARAAKSP
CCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
EDLKGFGNFEQPEPTYPNGTHICEVEIDPATGRTDVVAYTIVDDFGATANPILLAGQVHG
HHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCEEEEECCCC
GVAQGVGQALSEEVIYSEDGQLVTATFMDYSMPRADLLPFIQFETRNVPSSTNALGMKGA
HHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCC
GEAGTVGSTPAALNAVVDALYRAYGISHIEMPATPARIWQAIASASAEQA
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVLTPKFGMGASVLRKEDESFITGRGRYTDDITPPGTLCGYVLRSSMAKARFTVSSTEA
CEECCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCHH
ARAAPGVHLVLTGADTAHLGDLISGGMPKQPDGSKAPTRDIPILCRDRVQYVGDAVAFIV
HHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEE
ADTREQAQDAAELIEVDYEDEEPAVDTAAALQDGAPLVWPELGTNQAFLYHVGDKRKTDA
ECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEECCCCCCCCEEEEECCCCCCCHH
AFASADRVVKIAFINNRLVANYMETRSAIAEWKPDENRFVLTTGSQGVHSLQEILTRVFG
HHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHC
IPTSQLRVVTPDVGGGFGTKAFAYREYALVMEAAKRLGRPVKWTSDRNEHFLTDSQGRDN
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCCCCCC
AVTAEMALDQTGRFLAMRVELLANMGAYIHQFGPYIPVGGASMTTGVYDIQAIDVTVRGV
CEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEEEE
YTNTAPVDAYRGAGRPEAAFLIEKLVEVCARQMKLPREEIRRRNFIGVEQFPYRTPTGRR
EECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHCCCCCCCCCC
YDRCEFDGHMTLAMERAGWATFEERFAEAKKRGRIRGIGMSTYIEACAFAGSEPAYLTLN
CCCEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCCEEEEEC
GDGSVTLAIGTQSNGQGHATAYAQFVAEKLNLEIAKIHVHQGDTDVLKTGGGTGGSRSIP
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCHHEECCCCCCCCCCCC
LGGVSAARAGEDLAEKIKRIAAEEMEASPADIELVDGIARIVGTDRMMDFASIARAAKSP
CCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
EDLKGFGNFEQPEPTYPNGTHICEVEIDPATGRTDVVAYTIVDDFGATANPILLAGQVHG
HHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCEEEEECCCC
GVAQGVGQALSEEVIYSEDGQLVTATFMDYSMPRADLLPFIQFETRNVPSSTNALGMKGA
HHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCC
GEAGTVGSTPAALNAVVDALYRAYGISHIEMPATPARIWQAIASASAEQA
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]