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The map label for this gene is fabG [H]

Identifier: 110633207

GI number: 110633207

Start: 944054

End: 944794

Strand: Direct

Name: fabG [H]

Synonym: Meso_0850

Alternate gene names: 110633207

Gene position: 944054-944794 (Clockwise)

Preceding gene: 110633206

Following gene: 110633208

Centisome position: 21.4

GC content: 64.51

Gene sequence:

>741_bases
ATGACCCCCGTTGCGGTCGTCACGGGCGGTGCGTCCGGCAGCGGACTGGCAATCGCCGAACGGCTTATGGATGACGGCTG
GAAGGTGGCCGTTATCGACACCGACCAGGCTGCACTCGGCGAGGCGGAGGATTTCCTGGGGGGAGCTGACGCGATCTTCC
TTGCAGTGGATGTCACGGACGAAGATGAGGTGGCCGCGGCCCTTGATGAGGTGGTGGACGCGCTGGGGCCGATATCCGCA
CTGGTCAACACCGCGAGCGCCAAGCGCGAAGCGCTTTTCGAAGAAGTGAGCGCGGAGCTTTTCCGCGAGGCGCTGGAGGT
GAACCTGATCGGCTCCTTCATTGCCGCCGAAGCCGCGCTTGAACGGATGGGACACAGGCTTTCCGTCGTCAATCTGATAT
CCGTGAGCGGAGTGCGCGCCAATAGCGGCTGCACCGCCTATGGCGCATCCCAGGCGGGTGTGAAGATGATGACGGAGGTC
ATGGCCCTTGAACTGGGCAGCCGCGGCGTGCGGGTAAATTGCGTGGCGGTCGGCCCGATGGATACGGCTTCGCCCTTTAT
TCAGGACGCCGAGCGCCAGCGCCCTTGGCTGGAGCGCACGCCGCTTGGCCGTGCCGTAAGCGCGCGGGAGATGACGGCCG
CCATAGCCTATCTCCTCTCGCCCGAAGCTGGCGCAATTACCGGCCATACGCTGGTTATCGATGGCGGCTTTTCCGCCGCA
GGGCTGTTGCGCGTCGATTGA

Upstream 100 bases:

>100_bases
CGCATCCCAGGCGACCACCCTCGCTCGATGTGTTATCGTCCAGAGGAAGGAGGAGAGGAATGGGAACAGACGAACTCCAA
TTGGACGGGGCGGTCGCAAG

Downstream 100 bases:

>100_bases
TCCCTGCGCGCAATTCACAGGAAGCACTTGATATTCAACCCGAGGTCGTCCTAAGGGCTCCCGCACTCGGTTTATGATCT
GGCGCGAAAATGGATAATCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTPVAVVTGGASGSGLAIAERLMDDGWKVAVIDTDQAALGEAEDFLGGADAIFLAVDVTDEDEVAAALDEVVDALGPISA
LVNTASAKREALFEEVSAELFREALEVNLIGSFIAAEAALERMGHRLSVVNLISVSGVRANSGCTAYGASQAGVKMMTEV
MALELGSRGVRVNCVAVGPMDTASPFIQDAERQRPWLERTPLGRAVSAREMTAAIAYLLSPEAGAITGHTLVIDGGFSAA
GLLRVD

Sequences:

>Translated_246_residues
MTPVAVVTGGASGSGLAIAERLMDDGWKVAVIDTDQAALGEAEDFLGGADAIFLAVDVTDEDEVAAALDEVVDALGPISA
LVNTASAKREALFEEVSAELFREALEVNLIGSFIAAEAALERMGHRLSVVNLISVSGVRANSGCTAYGASQAGVKMMTEV
MALELGSRGVRVNCVAVGPMDTASPFIQDAERQRPWLERTPLGRAVSAREMTAAIAYLLSPEAGAITGHTLVIDGGFSAA
GLLRVD
>Mature_245_residues
TPVAVVTGGASGSGLAIAERLMDDGWKVAVIDTDQAALGEAEDFLGGADAIFLAVDVTDEDEVAAALDEVVDALGPISAL
VNTASAKREALFEEVSAELFREALEVNLIGSFIAAEAALERMGHRLSVVNLISVSGVRANSGCTAYGASQAGVKMMTEVM
ALELGSRGVRVNCVAVGPMDTASPFIQDAERQRPWLERTPLGRAVSAREMTAAIAYLLSPEAGAITGHTLVIDGGFSAAG
LLRVD

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=31.25, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=32, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=32.9218106995885, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=31.1111111111111, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI10190704, Length=241, Percent_Identity=29.045643153527, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=34.5, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI66933014, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI83715985, Length=181, Percent_Identity=34.2541436464088, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503817, Length=203, Percent_Identity=27.0935960591133, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=32.4894514767932, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=29.7520661157025, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=30.6772908366534, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=28.8065843621399, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=25.9541984732824, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=28.2157676348548, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=30.1652892561983, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=28.8617886178862, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=26.4462809917355, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789378, Length=242, Percent_Identity=26.0330578512397, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=28.9915966386555, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=35.655737704918, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=31.3008130081301, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.8367346938775, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=30.9803921568627, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.5220883534137, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=28.4, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=27.1604938271605, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=245, Percent_Identity=30.6122448979592, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=31.25, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=33.739837398374, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=241, Percent_Identity=32.7800829875519, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.9317269076305, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.9236947791165, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.9795918367347, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737361, Length=215, Percent_Identity=34.8837209302326, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356301, Length=206, Percent_Identity=29.6116504854369, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25419; Mature: 25288

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVAVVTGGASGSGLAIAERLMDDGWKVAVIDTDQAALGEAEDFLGGADAIFLAVDVTD
CCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCHHHCCHHHHCCCCCEEEEEEECCC
EDEVAAALDEVVDALGPISALVNTASAKREALFEEVSAELFREALEVNLIGSFIAAEAAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMGHRLSVVNLISVSGVRANSGCTAYGASQAGVKMMTEVMALELGSRGVRVNCVAVGPM
HHHCCCEEEEEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
DTASPFIQDAERQRPWLERTPLGRAVSAREMTAAIAYLLSPEAGAITGHTLVIDGGFSAA
CCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCEEEEECCCCCC
GLLRVD
CEEEEC
>Mature Secondary Structure 
TPVAVVTGGASGSGLAIAERLMDDGWKVAVIDTDQAALGEAEDFLGGADAIFLAVDVTD
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCHHHCCHHHHCCCCCEEEEEEECCC
EDEVAAALDEVVDALGPISALVNTASAKREALFEEVSAELFREALEVNLIGSFIAAEAAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMGHRLSVVNLISVSGVRANSGCTAYGASQAGVKMMTEVMALELGSRGVRVNCVAVGPM
HHHCCCEEEEEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
DTASPFIQDAERQRPWLERTPLGRAVSAREMTAAIAYLLSPEAGAITGHTLVIDGGFSAA
CCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCEEEEECCCCCC
GLLRVD
CEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]