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The map label for this gene is aldH [H]

Identifier: 110633201

GI number: 110633201

Start: 938238

End: 939764

Strand: Direct

Name: aldH [H]

Synonym: Meso_0844

Alternate gene names: 110633201

Gene position: 938238-939764 (Clockwise)

Preceding gene: 110633200

Following gene: 110633202

Centisome position: 21.26

GC content: 66.47

Gene sequence:

>1527_bases
ATGTCCCGAAATTTCAAACCGCGCGGAAAACACCTGATTGCCGGTGAGTGGGTGGGAAGTGAAGAAACCTTCGCCTCCGA
TCCCGCGACGGGTCCGTCCCACAGCTTCGCTGCCGGAACGGCGGCGGAAGTGGACCGCGCGGCCAAGGCCGCGGAAGAGG
CGTTCTGGACCTATGGCGCCACGAGCCGCGGGAAGCGCGCCGCCTTCCTGGACGCCATTGCGGACGAGATCGAGGCGCGC
GGCGAGGCGATCACCGAGATTGCCTCGCAGGAGACCGGGCTGCCGGAGGCCCGCATCAATGGAGAGCGCGGCCGCACCAC
CGGCCAGCTTCGCCTCTTTGCGGGCCATATTGAGAATGGCGAGTATCTCGACCGCCGGCATGATCCCGCCAATCCCGAGC
GCCAGCCGCTGCCCAAGCCGGACCTGAAGCTGATGCAGCTTCCGATAGGCCCGGTCGGCGTGTTCGGTGCGTCGAATTTT
CCGCTCGCCTTCTCCACCGCAGGCGGGGATACGGCATCGGCGCTTGCCGCCGGCTGCCCGGTGGTCGTCAAGGGCCACCC
AGCCCATCCGGGGACGGGCGAGCTGGTCGCGGAAGCCATCGAAGCCGCGATCAGGAAGACCGGCCAGCATCCCGGCGTCT
TCTCCCTCGTCCAAAGCAATACGAACGAGGCGGGCGAAGCGCTTGTAAAGCACCCGCTGATACGGGCCATCGGCTTTACC
GGCTCCCTTCGTGGCGGCCGCGCACTCTTCAACCTGGCGCAAGCGCGGCCCGATCCGATTCCGTTTTATGGCGAGCTTGG
CTCGGTCAACCCGCAGTTCCTGCTGCCGGCGGCTCTTGCCGCGCGCGCCGAAAAAATTGCCCAGGGCTGGGCGGCCTCGC
TCACCATGGGCGTCGGCCAGTTCTGCACCAATCCCGGCGTGGCGATCGCGCTTGATGGCAGCGATGTCGAGAGCTTTCTT
GGCGCGGCGCAGACCGCGCTGGAGCAGATCACCGAACAGCCCATGCTGACCGCAGGCATCGCGAATGCCTATCGCAGCGG
GCGCGACAAGGTCATCGGCCTGAACTGCGTGCGCTCGCGCCTTGCCTCCAAGGGGGAGGGCCGCAATGCCGGGCCTGACC
TTCTGGAGACCACCGGCGAGGAGTGGCTTTCCAACCCGGCCTTGCATGAGGAGGTGTTCGGCCCCTTCGGCATTGTCGTG
CGGGCGAGGAGCGAGAAGGAGATGCTTGAGATCGCCCGCCGGGTCGAAGGCCAGCTTACCTGTACTCTTCACATGGACGA
GGCGGATACCGCGCTTGCAGCGGCACTGATGCCGATCCTGAGCCGCAAGGCGGGCCGCGTCATCGCCAACGGCTTTCCCA
CAGGCGTCGAGGTAAGCGACGCGATGATGCATGGCGGGCCATACCCGGCGAGCACCAACGTCTCCACCACCTCCGTGGGC
ACGCTGGCGATCCGCCGCTTCCTGCGGCCGGTCGCCTATCAGGACATGCCGGAAAGCCTGCTTCCGGCAGATCTGAAGGA
GTTGTGA

Upstream 100 bases:

>100_bases
GCTCGTGGCTGACGCATTTCTGCTCGGTCGAAAGGTCGAGGTGGAAGCTTTCAACGATTAAGAAAGTTCGCATCCATCAG
TAGCGTTCTCGGAGTGTGCC

Downstream 100 bases:

>100_bases
AGGCACGCCGCCATGGAGCCCTTATGCGCTGCCGTTGATTGGGGAACGACCAATTTCCGCCTCTGGCTGCTGGACGCCGA
AGGCGGTGTGCTGGCCGAGC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MSRNFKPRGKHLIAGEWVGSEETFASDPATGPSHSFAAGTAAEVDRAAKAAEEAFWTYGATSRGKRAAFLDAIADEIEAR
GEAITEIASQETGLPEARINGERGRTTGQLRLFAGHIENGEYLDRRHDPANPERQPLPKPDLKLMQLPIGPVGVFGASNF
PLAFSTAGGDTASALAAGCPVVVKGHPAHPGTGELVAEAIEAAIRKTGQHPGVFSLVQSNTNEAGEALVKHPLIRAIGFT
GSLRGGRALFNLAQARPDPIPFYGELGSVNPQFLLPAALAARAEKIAQGWAASLTMGVGQFCTNPGVAIALDGSDVESFL
GAAQTALEQITEQPMLTAGIANAYRSGRDKVIGLNCVRSRLASKGEGRNAGPDLLETTGEEWLSNPALHEEVFGPFGIVV
RARSEKEMLEIARRVEGQLTCTLHMDEADTALAAALMPILSRKAGRVIANGFPTGVEVSDAMMHGGPYPASTNVSTTSVG
TLAIRRFLRPVAYQDMPESLLPADLKEL

Sequences:

>Translated_508_residues
MSRNFKPRGKHLIAGEWVGSEETFASDPATGPSHSFAAGTAAEVDRAAKAAEEAFWTYGATSRGKRAAFLDAIADEIEAR
GEAITEIASQETGLPEARINGERGRTTGQLRLFAGHIENGEYLDRRHDPANPERQPLPKPDLKLMQLPIGPVGVFGASNF
PLAFSTAGGDTASALAAGCPVVVKGHPAHPGTGELVAEAIEAAIRKTGQHPGVFSLVQSNTNEAGEALVKHPLIRAIGFT
GSLRGGRALFNLAQARPDPIPFYGELGSVNPQFLLPAALAARAEKIAQGWAASLTMGVGQFCTNPGVAIALDGSDVESFL
GAAQTALEQITEQPMLTAGIANAYRSGRDKVIGLNCVRSRLASKGEGRNAGPDLLETTGEEWLSNPALHEEVFGPFGIVV
RARSEKEMLEIARRVEGQLTCTLHMDEADTALAAALMPILSRKAGRVIANGFPTGVEVSDAMMHGGPYPASTNVSTTSVG
TLAIRRFLRPVAYQDMPESLLPADLKEL
>Mature_507_residues
SRNFKPRGKHLIAGEWVGSEETFASDPATGPSHSFAAGTAAEVDRAAKAAEEAFWTYGATSRGKRAAFLDAIADEIEARG
EAITEIASQETGLPEARINGERGRTTGQLRLFAGHIENGEYLDRRHDPANPERQPLPKPDLKLMQLPIGPVGVFGASNFP
LAFSTAGGDTASALAAGCPVVVKGHPAHPGTGELVAEAIEAAIRKTGQHPGVFSLVQSNTNEAGEALVKHPLIRAIGFTG
SLRGGRALFNLAQARPDPIPFYGELGSVNPQFLLPAALAARAEKIAQGWAASLTMGVGQFCTNPGVAIALDGSDVESFLG
AAQTALEQITEQPMLTAGIANAYRSGRDKVIGLNCVRSRLASKGEGRNAGPDLLETTGEEWLSNPALHEEVFGPFGIVVR
ARSEKEMLEIARRVEGQLTCTLHMDEADTALAAALMPILSRKAGRVIANGFPTGVEVSDAMMHGGPYPASTNVSTTSVGT
LAIRRFLRPVAYQDMPESLLPADLKEL

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=411, Percent_Identity=27.007299270073, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI25777721, Length=420, Percent_Identity=26.1904761904762, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787558, Length=495, Percent_Identity=26.8686868686869, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081896, Length=433, Percent_Identity=27.7136258660508, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788042, Length=399, Percent_Identity=25.8145363408521, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789015, Length=443, Percent_Identity=25.9593679458239, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787250, Length=268, Percent_Identity=28.7313432835821, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI133930964, Length=308, Percent_Identity=30.5194805194805, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995613, Length=268, Percent_Identity=31.7164179104478, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71995606, Length=268, Percent_Identity=31.7164179104478, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25143874, Length=474, Percent_Identity=23.6286919831224, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25143876, Length=474, Percent_Identity=23.6286919831224, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562198, Length=471, Percent_Identity=25.9023354564756, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324950, Length=420, Percent_Identity=25.952380952381, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319478, Length=302, Percent_Identity=28.1456953642384, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362580, Length=422, Percent_Identity=28.1990521327014, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI62472918, Length=422, Percent_Identity=28.1990521327014, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI62472926, Length=422, Percent_Identity=28.1990521327014, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI62472936, Length=422, Percent_Identity=28.1990521327014, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356737, Length=422, Percent_Identity=28.1990521327014, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666674, Length=454, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24585660, Length=216, Percent_Identity=28.2407407407407, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 53578; Mature: 53447

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNFKPRGKHLIAGEWVGSEETFASDPATGPSHSFAAGTAAEVDRAAKAAEEAFWTYGA
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
TSRGKRAAFLDAIADEIEARGEAITEIASQETGLPEARINGERGRTTGQLRLFAGHIENG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEEECCCC
EYLDRRHDPANPERQPLPKPDLKLMQLPIGPVGVFGASNFPLAFSTAGGDTASALAAGCP
HHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCEEEECCCCCHHHHHHCCCC
VVVKGHPAHPGTGELVAEAIEAAIRKTGQHPGVFSLVQSNTNEAGEALVKHPLIRAIGFT
EEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC
GSLRGGRALFNLAQARPDPIPFYGELGSVNPQFLLPAALAARAEKIAQGWAASLTMGVGQ
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCTNPGVAIALDGSDVESFLGAAQTALEQITEQPMLTAGIANAYRSGRDKVIGLNCVRSR
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHH
LASKGEGRNAGPDLLETTGEEWLSNPALHEEVFGPFGIVVRARSEKEMLEIARRVEGQLT
HHCCCCCCCCCCHHHHHCCHHHHCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHCCCEEE
CTLHMDEADTALAAALMPILSRKAGRVIANGFPTGVEVSDAMMHGGPYPASTNVSTTSVG
EEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCCCCCCCCCCHHHHH
TLAIRRFLRPVAYQDMPESLLPADLKEL
HHHHHHHHHHHHHHCCCHHHCCHHHHCC
>Mature Secondary Structure 
SRNFKPRGKHLIAGEWVGSEETFASDPATGPSHSFAAGTAAEVDRAAKAAEEAFWTYGA
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
TSRGKRAAFLDAIADEIEARGEAITEIASQETGLPEARINGERGRTTGQLRLFAGHIENG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEEECCCC
EYLDRRHDPANPERQPLPKPDLKLMQLPIGPVGVFGASNFPLAFSTAGGDTASALAAGCP
HHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCEEEECCCCCHHHHHHCCCC
VVVKGHPAHPGTGELVAEAIEAAIRKTGQHPGVFSLVQSNTNEAGEALVKHPLIRAIGFT
EEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC
GSLRGGRALFNLAQARPDPIPFYGELGSVNPQFLLPAALAARAEKIAQGWAASLTMGVGQ
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCTNPGVAIALDGSDVESFLGAAQTALEQITEQPMLTAGIANAYRSGRDKVIGLNCVRSR
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHH
LASKGEGRNAGPDLLETTGEEWLSNPALHEEVFGPFGIVVRARSEKEMLEIARRVEGQLT
HHCCCCCCCCCCHHHHHCCHHHHCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHCCCEEE
CTLHMDEADTALAAALMPILSRKAGRVIANGFPTGVEVSDAMMHGGPYPASTNVSTTSVG
EEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCCCCCCCCCCHHHHH
TLAIRRFLRPVAYQDMPESLLPADLKEL
HHHHHHHHHHHHHHCCCHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]