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The map label for this gene is xylH [H]

Identifier: 110633197

GI number: 110633197

Start: 932945

End: 934177

Strand: Direct

Name: xylH [H]

Synonym: Meso_0840

Alternate gene names: 110633197

Gene position: 932945-934177 (Clockwise)

Preceding gene: 110633196

Following gene: 110633198

Centisome position: 21.14

GC content: 62.12

Gene sequence:

>1233_bases
ATGTCTGAGCTGTCCGCCCATCAAAGAAAAACGGCAGAGGGTCTCGGCGAGGCCAAGGCCGAAGCGGCGATGTCCTCGAT
CGGCAGCCACCTGCAGACCCATGTGCGCGAATACGGCATGCTGATCGCGCTCGTGGTCATCATGGGCTTCTTCCAGGTGA
TGACGGACGGCACGCTGATGCGGCCGGTCAACCTCACCAATCTGGTCCTTCAGAACAGCTACATCGTCATCATGGCGCTC
GGCATGCTGCTCGTCATCGTGGCTGGCCATATCGATCTTTCGGTGGGGTCGGTGGCGGGCTTCGTGGGAGCCGTCGCGGC
AGTGATGCTGGTGCAGTACGATATCTCGCCGCTCGGGGTCATTCCGGCCTGCCTGCTGCTCGGCTTTGTTATCGGAGCGG
CCCAGGGCTACTGGATCGCCTATTGGCGCATACCCTCCTTCATCGTGACGCTGGCGGGAATGCTGGTTTTCCGCGGCCTC
ACTTTGTGGGTGCTTGCTGGCCAATCGGTCGGGCCGTTCCCGCGCTCCTTCCAGTTGCTCTCGACCGGATTCATCCCGGA
TCTCTTCGGCGTCGGCCGGCCCAATGTGACGGCGATCCTGCTCGGCGCGATAACGGCGGCGGCGCTTGTCTTCATGGCCA
TGCGCAACCGCCAGCGCCATACCAAATACGGCATGGAAGATGAGCCTTTCGCCTTCTTCCTCGCCAAGAACGGGCTGATC
GCGGCCGCCATCGTATTCCTTTCCTATCTGCTCTCCACCTATCGCGGCTTTCCGAACGTTCTCATCACAATGGCGGTGCT
GACGGTGATCTACACCTTCCTCACCAACTCGACCACGGTTGGCCGCCGCATCTATGCGCTGGGAGGAAACGAGAAGGCGG
CGAAGCTTTCCGGCATCCGGACGGAGCGGCTGACCTTCCTCACCTTCGCCAATATGGGCATGCTGGCGGCCCTTGCGGGC
CTCATCTTCGCCGCGCGCCTCAATACGGCGACGCCGAAGGCGGGCGTGGGCTTCGAGCTCGATGTGATCGCCGCCGTCTT
CATCGGCGGGGCGTCGATGTCGGGCGGCGTCGGCAAGATCACCGGAGCCGTGGTCGGCGCCTTCATCATGGGGGTGATGA
ACAACGGCATGTCGATCCTCGGCATCGGCATCGATTACCAGCAGGTCATCAAGGGCCTCGTGCTGCTCGCTGCGGTGATT
TTCGACGTCTACAACAAGAACAAGGCGGCTTGA

Upstream 100 bases:

>100_bases
CGCATCTATGTCATGAACGAGGGTGCGATCGTCGGCGAACTCGCCGCAAGCGAGGCAAGCCAGGAGAAGATCATGTCCAT
GATCGTGAGGTCGAAATCCA

Downstream 100 bases:

>100_bases
GCGAGAAATCGAGATGCATCTTTCGCAACTGAAAAAGGGCGGCGTGATCTGCCGCCGGGGCGCCGACGCGCGGCTCGTAA
ACGGCGCGCAGAGCACCTAT

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSELSAHQRKTAEGLGEAKAEAAMSSIGSHLQTHVREYGMLIALVVIMGFFQVMTDGTLMRPVNLTNLVLQNSYIVIMAL
GMLLVIVAGHIDLSVGSVAGFVGAVAAVMLVQYDISPLGVIPACLLLGFVIGAAQGYWIAYWRIPSFIVTLAGMLVFRGL
TLWVLAGQSVGPFPRSFQLLSTGFIPDLFGVGRPNVTAILLGAITAAALVFMAMRNRQRHTKYGMEDEPFAFFLAKNGLI
AAAIVFLSYLLSTYRGFPNVLITMAVLTVIYTFLTNSTTVGRRIYALGGNEKAAKLSGIRTERLTFLTFANMGMLAALAG
LIFAARLNTATPKAGVGFELDVIAAVFIGGASMSGGVGKITGAVVGAFIMGVMNNGMSILGIGIDYQQVIKGLVLLAAVI
FDVYNKNKAA

Sequences:

>Translated_410_residues
MSELSAHQRKTAEGLGEAKAEAAMSSIGSHLQTHVREYGMLIALVVIMGFFQVMTDGTLMRPVNLTNLVLQNSYIVIMAL
GMLLVIVAGHIDLSVGSVAGFVGAVAAVMLVQYDISPLGVIPACLLLGFVIGAAQGYWIAYWRIPSFIVTLAGMLVFRGL
TLWVLAGQSVGPFPRSFQLLSTGFIPDLFGVGRPNVTAILLGAITAAALVFMAMRNRQRHTKYGMEDEPFAFFLAKNGLI
AAAIVFLSYLLSTYRGFPNVLITMAVLTVIYTFLTNSTTVGRRIYALGGNEKAAKLSGIRTERLTFLTFANMGMLAALAG
LIFAARLNTATPKAGVGFELDVIAAVFIGGASMSGGVGKITGAVVGAFIMGVMNNGMSILGIGIDYQQVIKGLVLLAAVI
FDVYNKNKAA
>Mature_409_residues
SELSAHQRKTAEGLGEAKAEAAMSSIGSHLQTHVREYGMLIALVVIMGFFQVMTDGTLMRPVNLTNLVLQNSYIVIMALG
MLLVIVAGHIDLSVGSVAGFVGAVAAVMLVQYDISPLGVIPACLLLGFVIGAAQGYWIAYWRIPSFIVTLAGMLVFRGLT
LWVLAGQSVGPFPRSFQLLSTGFIPDLFGVGRPNVTAILLGAITAAALVFMAMRNRQRHTKYGMEDEPFAFFLAKNGLIA
AAIVFLSYLLSTYRGFPNVLITMAVLTVIYTFLTNSTTVGRRIYALGGNEKAAKLSGIRTERLTFLTFANMGMLAALAGL
IFAARLNTATPKAGVGFELDVIAAVFIGGASMSGGVGKITGAVVGAFIMGVMNNGMSILGIGIDYQQVIKGLVLLAAVIF
DVYNKNKAA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=377, Percent_Identity=38.1962864721485, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI145693152, Length=374, Percent_Identity=32.3529411764706, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790191, Length=153, Percent_Identity=44.4444444444444, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788896, Length=164, Percent_Identity=36.5853658536585, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790524, Length=157, Percent_Identity=40.7643312101911, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082395, Length=311, Percent_Identity=29.2604501607717, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788471, Length=381, Percent_Identity=30.1837270341207, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787793, Length=137, Percent_Identity=37.956204379562, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787794, Length=145, Percent_Identity=24.8275862068966, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43452; Mature: 43321

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSAHQRKTAEGLGEAKAEAAMSSIGSHLQTHVREYGMLIALVVIMGFFQVMTDGTLM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RPVNLTNLVLQNSYIVIMALGMLLVIVAGHIDLSVGSVAGFVGAVAAVMLVQYDISPLGV
CCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
IPACLLLGFVIGAAQGYWIAYWRIPSFIVTLAGMLVFRGLTLWVLAGQSVGPFPRSFQLL
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHH
STGFIPDLFGVGRPNVTAILLGAITAAALVFMAMRNRQRHTKYGMEDEPFAFFLAKNGLI
HHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCHH
AAAIVFLSYLLSTYRGFPNVLITMAVLTVIYTFLTNSTTVGRRIYALGGNEKAAKLSGIR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCC
TERLTFLTFANMGMLAALAGLIFAARLNTATPKAGVGFELDVIAAVFIGGASMSGGVGKI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHH
TGAVVGAFIMGVMNNGMSILGIGIDYQQVIKGLVLLAAVIFDVYNKNKAA
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SELSAHQRKTAEGLGEAKAEAAMSSIGSHLQTHVREYGMLIALVVIMGFFQVMTDGTLM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RPVNLTNLVLQNSYIVIMALGMLLVIVAGHIDLSVGSVAGFVGAVAAVMLVQYDISPLGV
CCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
IPACLLLGFVIGAAQGYWIAYWRIPSFIVTLAGMLVFRGLTLWVLAGQSVGPFPRSFQLL
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHH
STGFIPDLFGVGRPNVTAILLGAITAAALVFMAMRNRQRHTKYGMEDEPFAFFLAKNGLI
HHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCHH
AAAIVFLSYLLSTYRGFPNVLITMAVLTVIYTFLTNSTTVGRRIYALGGNEKAAKLSGIR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCC
TERLTFLTFANMGMLAALAGLIFAARLNTATPKAGVGFELDVIAAVFIGGASMSGGVGKI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHH
TGAVVGAFIMGVMNNGMSILGIGIDYQQVIKGLVLLAAVIFDVYNKNKAA
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]