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The map label for this gene is gbpR [H]

Identifier: 110633194

GI number: 110633194

Start: 928942

End: 929868

Strand: Reverse

Name: gbpR [H]

Synonym: Meso_0837

Alternate gene names: 110633194

Gene position: 929868-928942 (Counterclockwise)

Preceding gene: 110633204

Following gene: 110633193

Centisome position: 21.07

GC content: 62.89

Gene sequence:

>927_bases
ATGTCACGGCTCAAGCTCAGCCATTTCCGCCTTATCGCCGCCGTTGCGGAGCACGGCCAGCTCAGCCCGGCGGCGGCATC
GCTCTCCATGACGCAACCGGCAGCCTCGCGCATGTTGAGGGAGATCGAAAGGCTTATCGGCGTCCCTCTTTTCGAGCGGC
ACGCCAAGGGCATGAGCCTGACGGAGGTCGGCGGGCTGCTGGCGCGACATGCCGAAACGCTGCTCACCGAAATCCGAGAA
ACCGTCATTGAGGTTGAGGAATTCAAGCTCGGCAAGGGCGGGCGGGTGCGCGTCGGCGCCGTTACGGGAGCGGCGGTGGG
CTATGTGATGCCCGCGATTCAGAAACTGAAGGCCACTTCGCCCAATGCAGACGTGCATATCGACGTGGCACCGAGCGACA
CCCTGATCCCCGAACTCGTCTCAGGCCATCTCGATTTCGTGCTCGGCCGCGTGCCACCGCCTTTTGATCCGCGTAGTTTT
GTCGTTTCCCGCGGAAGAAACGAGATCGTCGACCTGGTGGTGAGGCGAAATCATCCGCTTGCGGGGGCCAATGCCATCTC
GATCGGCGAGCTCAGCGACTACGAGTGGGTGTTGCAGTCAAGCGGCGCACCTTTGCGCGTGGTCGTGGAGCAGGCGTTTC
TGGCCGCCGGAGGCACATTGCCCCGCAACATCATCAACACGACCTCGCTCCTGGCGATGATTGCGCTGCTCGTCACCTCG
GACGCAATCGCGCCGCTGTCGCGGGAAGTCTCGGATCTCCTCGGGGGAAACAGCGGGGGGCTGGGGCTTGCTGTTCTGCC
CATCCGCGAGGCGCTGGTCGTCGCTCCTTACCACCTGCTTTCGCTCAAGAGCCGGCCTCTATCGCCGCTGGCCTCAAGAC
TGAAAGAGCTTATCCTGCTGGAACTTGGGGGTTATGATCGGCCTTGA

Upstream 100 bases:

>100_bases
ATCCGTTGGCGAAACTATTGGAGATGGATTATACCAATCAAATGCATTTTTTGTTCTTTTGCATTACAAAACTGGTATGA
TGCTCCGTATGAAGGACGTC

Downstream 100 bases:

>100_bases
TGCCCTGGGCACATCAAATTCTTTCCGCCGTGTGTCTACCCGCATACGCTGACAGCCGGCGCCGTTCCTGATTCGCGCAG
ATTTGGAAGGAAGCGAGAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSRLKLSHFRLIAAVAEHGQLSPAAASLSMTQPAASRMLREIERLIGVPLFERHAKGMSLTEVGGLLARHAETLLTEIRE
TVIEVEEFKLGKGGRVRVGAVTGAAVGYVMPAIQKLKATSPNADVHIDVAPSDTLIPELVSGHLDFVLGRVPPPFDPRSF
VVSRGRNEIVDLVVRRNHPLAGANAISIGELSDYEWVLQSSGAPLRVVVEQAFLAAGGTLPRNIINTTSLLAMIALLVTS
DAIAPLSREVSDLLGGNSGGLGLAVLPIREALVVAPYHLLSLKSRPLSPLASRLKELILLELGGYDRP

Sequences:

>Translated_308_residues
MSRLKLSHFRLIAAVAEHGQLSPAAASLSMTQPAASRMLREIERLIGVPLFERHAKGMSLTEVGGLLARHAETLLTEIRE
TVIEVEEFKLGKGGRVRVGAVTGAAVGYVMPAIQKLKATSPNADVHIDVAPSDTLIPELVSGHLDFVLGRVPPPFDPRSF
VVSRGRNEIVDLVVRRNHPLAGANAISIGELSDYEWVLQSSGAPLRVVVEQAFLAAGGTLPRNIINTTSLLAMIALLVTS
DAIAPLSREVSDLLGGNSGGLGLAVLPIREALVVAPYHLLSLKSRPLSPLASRLKELILLELGGYDRP
>Mature_307_residues
SRLKLSHFRLIAAVAEHGQLSPAAASLSMTQPAASRMLREIERLIGVPLFERHAKGMSLTEVGGLLARHAETLLTEIRET
VIEVEEFKLGKGGRVRVGAVTGAAVGYVMPAIQKLKATSPNADVHIDVAPSDTLIPELVSGHLDFVLGRVPPPFDPRSFV
VSRGRNEIVDLVVRRNHPLAGANAISIGELSDYEWVLQSSGAPLRVVVEQAFLAAGGTLPRNIINTTSLLAMIALLVTSD
AIAPLSREVSDLLGGNSGGLGLAVLPIREALVVAPYHLLSLKSRPLSPLASRLKELILLELGGYDRP

Specific function: Activator of the expression of chvE when bound to its inducer and represses its expression in the absence of inducer (L- arabinose, D-fucose or D-galactose). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=306, Percent_Identity=28.4313725490196, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789506, Length=294, Percent_Identity=25.1700680272109, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081904, Length=242, Percent_Identity=28.099173553719, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=233, Percent_Identity=24.8927038626609, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI145693105, Length=208, Percent_Identity=28.3653846153846, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI2367136, Length=123, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790399, Length=308, Percent_Identity=25.6493506493506, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789440, Length=138, Percent_Identity=26.8115942028986, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32841; Mature: 32710

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLKLSHFRLIAAVAEHGQLSPAAASLSMTQPAASRMLREIERLIGVPLFERHAKGMSL
CCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCH
TEVGGLLARHAETLLTEIRETVIEVEEFKLGKGGRVRVGAVTGAAVGYVMPAIQKLKATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
PNADVHIDVAPSDTLIPELVSGHLDFVLGRVPPPFDPRSFVVSRGRNEIVDLVVRRNHPL
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCC
AGANAISIGELSDYEWVLQSSGAPLRVVVEQAFLAAGGTLPRNIINTTSLLAMIALLVTS
CCCCEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
DAIAPLSREVSDLLGGNSGGLGLAVLPIREALVVAPYHLLSLKSRPLSPLASRLKELILL
HHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
ELGGYDRP
HCCCCCCC
>Mature Secondary Structure 
SRLKLSHFRLIAAVAEHGQLSPAAASLSMTQPAASRMLREIERLIGVPLFERHAKGMSL
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCH
TEVGGLLARHAETLLTEIRETVIEVEEFKLGKGGRVRVGAVTGAAVGYVMPAIQKLKATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
PNADVHIDVAPSDTLIPELVSGHLDFVLGRVPPPFDPRSFVVSRGRNEIVDLVVRRNHPL
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCC
AGANAISIGELSDYEWVLQSSGAPLRVVVEQAFLAAGGTLPRNIINTTSLLAMIALLVTS
CCCCEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
DAIAPLSREVSDLLGGNSGGLGLAVLPIREALVVAPYHLLSLKSRPLSPLASRLKELILL
HHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
ELGGYDRP
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8253677; 2156804 [H]