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The map label for this gene is frk [H]

Identifier: 110633193

GI number: 110633193

Start: 927923

End: 928843

Strand: Reverse

Name: frk [H]

Synonym: Meso_0836

Alternate gene names: 110633193

Gene position: 928843-927923 (Counterclockwise)

Preceding gene: 110633194

Following gene: 110633188

Centisome position: 21.05

GC content: 63.84

Gene sequence:

>921_bases
ATGATCCTGTGCTGCGGAGAAGCATTGATCGACATGCTGCCACGCGAAACGGCCGATGGCGAAGCCGCTTTCGTGCCACA
TGTGGGCGGCTCGGTCTTCAACACCGCGATCGCCCTCGGGCGGCTTGAAGTTCCCGTCTCCTTCTTTTCCGGCCTCTCGG
AGGATCTTTTCGGAGTGCGCCTTCAAGACACGCTGCGCGCCAGTGGCGTCGACCTCAGCCATGCCATCATTTCAACCCGC
CCGACAACGCTTGCCTTCGTGTCTCTCAACGAGGGCCAGGCGAGCTACCATTTCTATGACGAAAACACCGCCGGGCGAAT
GCTGTTCGAAGCCGACCTGCCGGACCTGGATGAGAGCGTGGAGGCCATGCTTTTCGGCGGCATCAGCCTTGCACCCGAAC
CTTGCGGCGGCACCTTCGAGGCGCTGATGACGCGTGAGAGCCCCACGCGCGTCACCATGCTCGACCCAAATATCCGCCAG
GCCTTCATCCGCGATCCGCTCGCGCATAAGGCACGCATGCGGCGCATGATGGCGATCGCGGACATTATCAAGATTTCGGA
AGAGGACCTTGCCTGGTTCGGAGGCCCCGCTTCGGCCGGAGAGGCAGCACAGGTGCTTCTCGCCGCCGGAACAAGGCTCG
TGGTCGTCACCAGCGGCGGCAAGGGCGCGTCCGCCTATTGGCGGGGCGGCAGCTTCGTCATCAGTGCCGTGAACGTGAAG
GTCGCGGACACGGTCGGCGCGGGCGATTCCTTCAACGCCGGCATATTGGCGGCGCTCAGGAAAGCGGGCTATCTCAAGAA
ATCACGCCTCGCCTCGCTGACGACCGAGGTCGTCCGGGATGCCCTCTCCTTCGCCACGCGCGTTGCGGCCGTTACGGTCT
CGCGCGCGGGTGCCAATCCGCCCTGGGCGGATGAGGTGTAA

Upstream 100 bases:

>100_bases
GATGCCCTGGGCACATCAAATTCTTTCCGCCGTGTGTCTACCCGCATACGCTGACAGCCGGCGCCGTTCCTGATTCGCGC
AGATTTGGAAGGAAGCGAGA

Downstream 100 bases:

>100_bases
TTGCGCCCTTTCGCGCCCCCCTCTGGCCTGCCGGCCATCTCCCCCACAAGGGGGGAGATTGCGCTTGCAGCTTGCTCCGT
CACCTATTCAGCAAGACCGG

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MILCCGEALIDMLPRETADGEAAFVPHVGGSVFNTAIALGRLEVPVSFFSGLSEDLFGVRLQDTLRASGVDLSHAIISTR
PTTLAFVSLNEGQASYHFYDENTAGRMLFEADLPDLDESVEAMLFGGISLAPEPCGGTFEALMTRESPTRVTMLDPNIRQ
AFIRDPLAHKARMRRMMAIADIIKISEEDLAWFGGPASAGEAAQVLLAAGTRLVVVTSGGKGASAYWRGGSFVISAVNVK
VADTVGAGDSFNAGILAALRKAGYLKKSRLASLTTEVVRDALSFATRVAAVTVSRAGANPPWADEV

Sequences:

>Translated_306_residues
MILCCGEALIDMLPRETADGEAAFVPHVGGSVFNTAIALGRLEVPVSFFSGLSEDLFGVRLQDTLRASGVDLSHAIISTR
PTTLAFVSLNEGQASYHFYDENTAGRMLFEADLPDLDESVEAMLFGGISLAPEPCGGTFEALMTRESPTRVTMLDPNIRQ
AFIRDPLAHKARMRRMMAIADIIKISEEDLAWFGGPASAGEAAQVLLAAGTRLVVVTSGGKGASAYWRGGSFVISAVNVK
VADTVGAGDSFNAGILAALRKAGYLKKSRLASLTTEVVRDALSFATRVAAVTVSRAGANPPWADEV
>Mature_306_residues
MILCCGEALIDMLPRETADGEAAFVPHVGGSVFNTAIALGRLEVPVSFFSGLSEDLFGVRLQDTLRASGVDLSHAIISTR
PTTLAFVSLNEGQASYHFYDENTAGRMLFEADLPDLDESVEAMLFGGISLAPEPCGGTFEALMTRESPTRVTMLDPNIRQ
AFIRDPLAHKARMRRMMAIADIIKISEEDLAWFGGPASAGEAAQVLLAAGTRLVVVTSGGKGASAYWRGGSFVISAVNVK
VADTVGAGDSFNAGILAALRKAGYLKKSRLASLTTEVVRDALSFATRVAAVTVSRAGANPPWADEV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1790193, Length=309, Percent_Identity=26.537216828479, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 32356; Mature: 32356

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILCCGEALIDMLPRETADGEAAFVPHVGGSVFNTAIALGRLEVPVSFFSGLSEDLFGVR
CEEECCHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCEECCHHHHCCCCHHHHCEE
LQDTLRASGVDLSHAIISTRPTTLAFVSLNEGQASYHFYDENTAGRMLFEADLPDLDESV
HHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCHHHH
EAMLFGGISLAPEPCGGTFEALMTRESPTRVTMLDPNIRQAFIRDPLAHKARMRRMMAIA
HHHHHCCCCCCCCCCCCHHHHHEECCCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHH
DIIKISEEDLAWFGGPASAGEAAQVLLAAGTRLVVVTSGGKGASAYWRGGSFVISAVNVK
HHHHCCCCHHEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCEEECCCEEEEEEEEEE
VADTVGAGDSFNAGILAALRKAGYLKKSRLASLTTEVVRDALSFATRVAAVTVSRAGANP
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
PWADEV
CCCCCC
>Mature Secondary Structure
MILCCGEALIDMLPRETADGEAAFVPHVGGSVFNTAIALGRLEVPVSFFSGLSEDLFGVR
CEEECCHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCEECCHHHHCCCCHHHHCEE
LQDTLRASGVDLSHAIISTRPTTLAFVSLNEGQASYHFYDENTAGRMLFEADLPDLDESV
HHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCHHHH
EAMLFGGISLAPEPCGGTFEALMTRESPTRVTMLDPNIRQAFIRDPLAHKARMRRMMAIA
HHHHHCCCCCCCCCCCCHHHHHEECCCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHH
DIIKISEEDLAWFGGPASAGEAAQVLLAAGTRLVVVTSGGKGASAYWRGGSFVISAVNVK
HHHHCCCCHHEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCEEECCCEEEEEEEEEE
VADTVGAGDSFNAGILAALRKAGYLKKSRLASLTTEVVRDALSFATRVAAVTVSRAGANP
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
PWADEV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8932706 [H]