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The map label for this gene is xanA [H]

Identifier: 110633188

GI number: 110633188

Start: 921065

End: 922420

Strand: Reverse

Name: xanA [H]

Synonym: Meso_0831

Alternate gene names: 110633188

Gene position: 922420-921065 (Counterclockwise)

Preceding gene: 110633193

Following gene: 110633186

Centisome position: 20.9

GC content: 60.84

Gene sequence:

>1356_bases
ATGAGTGCTCCCTTCAAGGCCTATGATGTCCGCGGCCGAATCCCGGAGGAGATCAACAGCCCCTTCGCCTATCGCTTCGC
CCAGGCGACGAAGGAGGCACTTGGGCCAAAATCTGTCGTGATCGGTCATGACATGCGGCTCGACAGTCCTGCTCTTGCCG
GCGCGCTCACGCAGGGACTGCTCGACAGCGGCGTTGACGTGCTGCCCGTCGGCCAATGCGGCACGGAGGAAGTTTACTTC
CATACCGCCCGTTCCGGCGCCGATGCGGGACTTATGGTCACCGCGAGCCATAACCCGCCCGACTATAACGGCATCAAGAT
GGTGCTGAAGGGCGCTGCGGCCGCCACGCCCGACAACGCCTTCAACGCCATCGAAGAGCTGATGCGCTCAGACAAAGTGT
TCCCGACTGCATCGAGCTACAAGGAGCGAGGAACGCTTCATCCGCTCTGCGACCGCAATACCTATATCGAGCGCCTGCTC
GAGGAGGTTGCGGGGCAAAATTTGAGACCCCTGAAGATCGTCTGCCACGCGGGCAATGGCTGCGCCGGGCCAATCATCGA
CCTCCTCGAAAAGCATCTGCCCTTCACCTTCATAAAGATCGATCACGATCCAGATCCGTGGCTTCCCAACGGCGTGCCCA
ATCCTCTTCTTCCGGAAAAGCGCGAGAAGGCAAGCAGGGCGGTGGTGGAGCAAGGCGCCGACCTTGCCATCGCCTGGGAC
GGAGATTTCGACCGCTGCTTTCTCTACGATCACAAGGGGCGGTTCGTGGAGGGATACTACCTCGTCGGCATGATTGCCCA
GCGGATGCTGAAGAAGGCTCCGGGCGGCACGATCCTTTACGATCCACGCCTCACCTGGAACACGATCGACGTCGTGGAAA
GAGCCGGCGGTGTGGCGAAGCCCTGCCGCACGGGCCACGCCTATTTCAAGCGCATGATGCGCGAGGAGAATGCCATTTAC
GGCGGCGAGATGAGCGCACACCATTATTTCCGCGATTTCGCCTATTGCGATTCGGGCATGCTCACCTGGCTCGACGTCGT
TTGTGAGCTGTCAGAAACCGGCGCAACCCTGGCCGAGACCTTGGAGGAACGCATCGCCGCCTTCCCCTGCTCCGGCGAGA
TCAATTTCACCGTTGCCGATTCCAAGGCGGTGCAGGAGCGCGTGGCAGAGCACTACCAGCGCTTCAACCCGGAACTGGAG
ACGATAGACGGGCTCGGGATGGCCTTCGACAATTGGCGTTTCAATCTGCGCGCCTCCAACACCGAGCCGCTGCTGCGTCT
CAATGTGGAAACCCGCGCCGACCAGCAGCTCCTGGAGCAGAAAGTGCAGGAATTGCGCGGGTTGATCGAAGCCTAG

Upstream 100 bases:

>100_bases
GCGAACAGCTTGGCGTTTGCGTTGCCCAAAGTTCGCCTCTAACAAATAGTCATCTTCGTACTCAGCAAATCAGTTCGTGC
CAGTCAGGAGACAGAATTAT

Downstream 100 bases:

>100_bases
CGCATCGGAAGCCGTCGCAGAGACGGCTCCGCCGAATAGGAGCTCTGCCGTCAATCAGAAAACCGGTCGCAAGATTTGGC
TGGGGCGGCAGGATTCACAG

Product: phosphomannomutase

Products: NA

Alternate protein names: Phosphoglucomutase; PGM; Glucose phosphomutase; Phosphomannomutase; PMM [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSAPFKAYDVRGRIPEEINSPFAYRFAQATKEALGPKSVVIGHDMRLDSPALAGALTQGLLDSGVDVLPVGQCGTEEVYF
HTARSGADAGLMVTASHNPPDYNGIKMVLKGAAAATPDNAFNAIEELMRSDKVFPTASSYKERGTLHPLCDRNTYIERLL
EEVAGQNLRPLKIVCHAGNGCAGPIIDLLEKHLPFTFIKIDHDPDPWLPNGVPNPLLPEKREKASRAVVEQGADLAIAWD
GDFDRCFLYDHKGRFVEGYYLVGMIAQRMLKKAPGGTILYDPRLTWNTIDVVERAGGVAKPCRTGHAYFKRMMREENAIY
GGEMSAHHYFRDFAYCDSGMLTWLDVVCELSETGATLAETLEERIAAFPCSGEINFTVADSKAVQERVAEHYQRFNPELE
TIDGLGMAFDNWRFNLRASNTEPLLRLNVETRADQQLLEQKVQELRGLIEA

Sequences:

>Translated_451_residues
MSAPFKAYDVRGRIPEEINSPFAYRFAQATKEALGPKSVVIGHDMRLDSPALAGALTQGLLDSGVDVLPVGQCGTEEVYF
HTARSGADAGLMVTASHNPPDYNGIKMVLKGAAAATPDNAFNAIEELMRSDKVFPTASSYKERGTLHPLCDRNTYIERLL
EEVAGQNLRPLKIVCHAGNGCAGPIIDLLEKHLPFTFIKIDHDPDPWLPNGVPNPLLPEKREKASRAVVEQGADLAIAWD
GDFDRCFLYDHKGRFVEGYYLVGMIAQRMLKKAPGGTILYDPRLTWNTIDVVERAGGVAKPCRTGHAYFKRMMREENAIY
GGEMSAHHYFRDFAYCDSGMLTWLDVVCELSETGATLAETLEERIAAFPCSGEINFTVADSKAVQERVAEHYQRFNPELE
TIDGLGMAFDNWRFNLRASNTEPLLRLNVETRADQQLLEQKVQELRGLIEA
>Mature_450_residues
SAPFKAYDVRGRIPEEINSPFAYRFAQATKEALGPKSVVIGHDMRLDSPALAGALTQGLLDSGVDVLPVGQCGTEEVYFH
TARSGADAGLMVTASHNPPDYNGIKMVLKGAAAATPDNAFNAIEELMRSDKVFPTASSYKERGTLHPLCDRNTYIERLLE
EVAGQNLRPLKIVCHAGNGCAGPIIDLLEKHLPFTFIKIDHDPDPWLPNGVPNPLLPEKREKASRAVVEQGADLAIAWDG
DFDRCFLYDHKGRFVEGYYLVGMIAQRMLKKAPGGTILYDPRLTWNTIDVVERAGGVAKPCRTGHAYFKRMMREENAIYG
GEMSAHHYFRDFAYCDSGMLTWLDVVCELSETGATLAETLEERIAAFPCSGEINFTVADSKAVQERVAEHYQRFNPELET
IDGLGMAFDNWRFNLRASNTEPLLRLNVETRADQQLLEQKVQELRGLIEA

Specific function: Involved in xanthan production [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=450, Percent_Identity=49.5555555555556, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI1789566, Length=460, Percent_Identity=27.1739130434783, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2; =5.4.2.8 [H]

Molecular weight: Translated: 50069; Mature: 49938

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00141 ASP_PROTEASE ; PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPFKAYDVRGRIPEEINSPFAYRFAQATKEALGPKSVVIGHDMRLDSPALAGALTQGL
CCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
LDSGVDVLPVGQCGTEEVYFHTARSGADAGLMVTASHNPPDYNGIKMVLKGAAAATPDNA
HHCCCCEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHH
FNAIEELMRSDKVFPTASSYKERGTLHPLCDRNTYIERLLEEVAGQNLRPLKIVCHAGNG
HHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCC
CAGPIIDLLEKHLPFTFIKIDHDPDPWLPNGVPNPLLPEKREKASRAVVEQGADLAIAWD
CCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
GDFDRCFLYDHKGRFVEGYYLVGMIAQRMLKKAPGGTILYDPRLTWNTIDVVERAGGVAK
CCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCC
PCRTGHAYFKRMMREENAIYGGEMSAHHYFRDFAYCDSGMLTWLDVVCELSETGATLAET
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LEERIAAFPCSGEINFTVADSKAVQERVAEHYQRFNPELETIDGLGMAFDNWRFNLRASN
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHCCCCEEECCEEEEEEECC
TEPLLRLNVETRADQQLLEQKVQELRGLIEA
CCCEEEEECHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAPFKAYDVRGRIPEEINSPFAYRFAQATKEALGPKSVVIGHDMRLDSPALAGALTQGL
CCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
LDSGVDVLPVGQCGTEEVYFHTARSGADAGLMVTASHNPPDYNGIKMVLKGAAAATPDNA
HHCCCCEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHH
FNAIEELMRSDKVFPTASSYKERGTLHPLCDRNTYIERLLEEVAGQNLRPLKIVCHAGNG
HHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCC
CAGPIIDLLEKHLPFTFIKIDHDPDPWLPNGVPNPLLPEKREKASRAVVEQGADLAIAWD
CCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
GDFDRCFLYDHKGRFVEGYYLVGMIAQRMLKKAPGGTILYDPRLTWNTIDVVERAGGVAK
CCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCC
PCRTGHAYFKRMMREENAIYGGEMSAHHYFRDFAYCDSGMLTWLDVVCELSETGATLAET
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LEERIAAFPCSGEINFTVADSKAVQERVAEHYQRFNPELETIDGLGMAFDNWRFNLRASN
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHCCCCEEECCEEEEEEECC
TEPLLRLNVETRADQQLLEQKVQELRGLIEA
CCCEEEEECHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280 [H]