| Definition | Mesorhizobium sp. BNC1, complete genome. |
|---|---|
| Accession | NC_008254 |
| Length | 4,412,446 |
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The map label for this gene is cya [H]
Identifier: 110633150
GI number: 110633150
Start: 880438
End: 882825
Strand: Direct
Name: cya [H]
Synonym: Meso_0793
Alternate gene names: 110633150
Gene position: 880438-882825 (Clockwise)
Preceding gene: 110633149
Following gene: 110633151
Centisome position: 19.95
GC content: 59.63
Gene sequence:
>2388_bases ATGATTATCGGGGTGAAGGGAACAAGGCAAAAGGATCGGCAGGGCGATCCGGCCACACGCTACGAAACGAAGAACCAGGA TCAAAAGTCGAATACACCTTACCTGGTCGGACTGTTTCTTGCTGGCATCGCGCTTTACCTGAAATCAATGATGCCGCTTC TCTCCCGGCCGGAAAAGGAAGGCACGGAATCTGCAAAGGAGCCGGTCGGGCCAACCGAACAGCAGCCGGACCTGGTAGCT GAGTCGGAGCCCGAGCAGGCCCCGGTGAGCGAAGATGAAGATGAAGCCTTGCCGGATAAGCTCCCTCTGGGATCTGGAGA GCAACTGGCCGATTTCATACCTCCGGCGCAGTTCATGCAGATCGAAAGCTCGGCCATCGAGTTCGTCGCCTTCAGAACGC CGCGTGAATGGAATGGATTTTTCGCGCCACCGCCTGTTTCGCTGGCGGCGAACGACAACAGGGCTGCGCCGCCGGGCGGA GTTGCCCCCGCCGAGAACGACATTGGCCGGGAGCAACCCGGCGCCGAGACGCCTGAGCCGGGTGATCCGGATCACCAGCA TCCTCACGACAACGACGACGACGATGATGATGATGATGAGCACGAAGGCGAGGATGGAGAAACCGACGTCGATGACGGGG ATGACACCTCCCAAAACCGAGCGCCTCGTTTGGCAGGGCCTGTCTACCTCAACGACATATCCGGTTGTGCCGTGCTGGCG ATTGCCATGGGCGAACTCCTGCGCAATGCGCAAGATCCTGACGGCGACGCTCTCTCTGTTAAAAATCTGACCGTGTCTTC AGGGATGTTGGTCCAAGCCGACGAAGGCTGGCTTTACCGCGGCTGGCCGACAACGGAAGGCTTGGTCACCGTCAGATATC AAGTGACGGATGGCGAGTTTTCCGTCGACCAGGTGGCATATTTCTCCGTGAGCAAATCCTTCATCGAAGGGTCTCCGGCT GATGATCTCATTCTCGGAACGCCCTGTGCTGACGAAATCGACGCCGGTTGCGGCGACGACAATATCGATTCCCGCGGCGG CGACGACCTCATCTCGGCGGGACCTGGCAACGACCACATCGTTGCGGGAGCCGGCGACGATGTCGTGCACGCTGGATCGG GCGATGACATCGTGTTCGGAGGAGCTGGAAATGATCATCTCGCCGGCGAAAGTGGGAACGACCGGCTCTACGGCCAGGAT GGCGACGATTTCCTGTTCGGTGATGCCGGGGACGACACGCTGCATGGCGGCGCCGGACGAGACATCCTGCACGGTGACGA TGGCCATGACAGCCTCAAAGGAGGCGAAGACGAAGATATCCTGCTTGCAGGTGCCGGCGATGATACGGCCGATGGGGGAG AAGGCGCGGACCTGCTGGATGGGGCCGAGGGGGACGACTGGCTGCAGGGCCGGGCAGGTGACGATGTCCTGCTGGATGGA CCCGGAGCAGACAAGGTGGAAGGCGGTGACGGGAATGACCGGGTCGTTCCCACACATGACGGCACGGCCGACCGCTTTGA CGGCGGCAAAGGGCACGACACTCTCGACTACGCATCAACCGAGGCCCGCGTTGCCGTGGATCTGGAAAGCGGTACGGCCA AGATCGGGGAATCCCCTGATGATCTTGTCTCATGCTTCGACGCCGTGGTGGGCGGTGCCGCAGACGACGAATTGAAAGGA AGCGCCGGGGGTGAGAAGCTCGATGGCGGGGCGGGTGACGACATACTCGATGGCAAGGGAGGCCAGGATACACTTCTGGG CGGGGCGGGCGATGATGTGATCGCCGATGGCTCGGGATCGGATGTGATCGATGCCGGCGACGGAAACGACAGGATTTCCG CCGCGGCTGACGGCGACGACGATCATTATGATGGGGCGGAAGGTTGCGACACGCTCGACTATTCGCAAACCAGCCAAGGT GTCACGGTGGACCTCAAGGAGGGACTCGCCTGCGGCGAGGAAACGGGTCGCGATACGATCGTCTCGATGGAAAACGTGAT CGGCGGCACGGGCAACGATCATTTCATTGTCGACCACGCCTCCGCGTCTCTCACGGGGGGAGACGGGGAGGATGTTTTCG AGTTTTGTTATAGCCCTTCTTCCCCGCCCGCTGAGACATCTCATCTTATCTTCGATTTCACCGTCGGAGATCGGATACGG ATGTCCAAATACGATCTGTTCAAGGAGGTCATGGACGAAGTCGCAGATCATTTCGAAGACATCTACGGCGAACAATCCGA CGATGAGATACCGATAAGGTTCAGCCACGATTGGAACGATGAAATGGCGCGCACGATTGTGGAGGCCGACCTGAATGACG ACGCGATTTGGGAAACCACGGTTTACCTTCAAGGCTATCACGTTCTGATGATAGTCGAGCAGGCGTAG
Upstream 100 bases:
>100_bases ACATCCTTTCCGGCGTTTCCAGACGCGAGGCCGTTGCAGCCGATGGTTCGTCTGACACGAACGACAAGAAGGAGCGCGCT GTATCGGCGCGGGTGTTGGC
Downstream 100 bases:
>100_bases GGGGGGGGATATGAGCAAGACCGAGACAAGTCACGCTTTCAAGATCGGCCCGCACATATTCATGGGATCCGTCCTGGCTT TTCTGCTCGTAGCCGGGGCA
Product: hemolysin-type calcium-binding region
Products: NA
Alternate protein names: AC-HLY; ACT; Cyclolysin; ATP pyrophosphate-lyase; Adenylyl cyclase [H]
Number of amino acids: Translated: 795; Mature: 795
Protein sequence:
>795_residues MIIGVKGTRQKDRQGDPATRYETKNQDQKSNTPYLVGLFLAGIALYLKSMMPLLSRPEKEGTESAKEPVGPTEQQPDLVA ESEPEQAPVSEDEDEALPDKLPLGSGEQLADFIPPAQFMQIESSAIEFVAFRTPREWNGFFAPPPVSLAANDNRAAPPGG VAPAENDIGREQPGAETPEPGDPDHQHPHDNDDDDDDDDEHEGEDGETDVDDGDDTSQNRAPRLAGPVYLNDISGCAVLA IAMGELLRNAQDPDGDALSVKNLTVSSGMLVQADEGWLYRGWPTTEGLVTVRYQVTDGEFSVDQVAYFSVSKSFIEGSPA DDLILGTPCADEIDAGCGDDNIDSRGGDDLISAGPGNDHIVAGAGDDVVHAGSGDDIVFGGAGNDHLAGESGNDRLYGQD GDDFLFGDAGDDTLHGGAGRDILHGDDGHDSLKGGEDEDILLAGAGDDTADGGEGADLLDGAEGDDWLQGRAGDDVLLDG PGADKVEGGDGNDRVVPTHDGTADRFDGGKGHDTLDYASTEARVAVDLESGTAKIGESPDDLVSCFDAVVGGAADDELKG SAGGEKLDGGAGDDILDGKGGQDTLLGGAGDDVIADGSGSDVIDAGDGNDRISAAADGDDDHYDGAEGCDTLDYSQTSQG VTVDLKEGLACGEETGRDTIVSMENVIGGTGNDHFIVDHASASLTGGDGEDVFEFCYSPSSPPAETSHLIFDFTVGDRIR MSKYDLFKEVMDEVADHFEDIYGEQSDDEIPIRFSHDWNDEMARTIVEADLNDDAIWETTVYLQGYHVLMIVEQA
Sequences:
>Translated_795_residues MIIGVKGTRQKDRQGDPATRYETKNQDQKSNTPYLVGLFLAGIALYLKSMMPLLSRPEKEGTESAKEPVGPTEQQPDLVA ESEPEQAPVSEDEDEALPDKLPLGSGEQLADFIPPAQFMQIESSAIEFVAFRTPREWNGFFAPPPVSLAANDNRAAPPGG VAPAENDIGREQPGAETPEPGDPDHQHPHDNDDDDDDDDEHEGEDGETDVDDGDDTSQNRAPRLAGPVYLNDISGCAVLA IAMGELLRNAQDPDGDALSVKNLTVSSGMLVQADEGWLYRGWPTTEGLVTVRYQVTDGEFSVDQVAYFSVSKSFIEGSPA DDLILGTPCADEIDAGCGDDNIDSRGGDDLISAGPGNDHIVAGAGDDVVHAGSGDDIVFGGAGNDHLAGESGNDRLYGQD GDDFLFGDAGDDTLHGGAGRDILHGDDGHDSLKGGEDEDILLAGAGDDTADGGEGADLLDGAEGDDWLQGRAGDDVLLDG PGADKVEGGDGNDRVVPTHDGTADRFDGGKGHDTLDYASTEARVAVDLESGTAKIGESPDDLVSCFDAVVGGAADDELKG SAGGEKLDGGAGDDILDGKGGQDTLLGGAGDDVIADGSGSDVIDAGDGNDRISAAADGDDDHYDGAEGCDTLDYSQTSQG VTVDLKEGLACGEETGRDTIVSMENVIGGTGNDHFIVDHASASLTGGDGEDVFEFCYSPSSPPAETSHLIFDFTVGDRIR MSKYDLFKEVMDEVADHFEDIYGEQSDDEIPIRFSHDWNDEMARTIVEADLNDDAIWETTVYLQGYHVLMIVEQA >Mature_795_residues MIIGVKGTRQKDRQGDPATRYETKNQDQKSNTPYLVGLFLAGIALYLKSMMPLLSRPEKEGTESAKEPVGPTEQQPDLVA ESEPEQAPVSEDEDEALPDKLPLGSGEQLADFIPPAQFMQIESSAIEFVAFRTPREWNGFFAPPPVSLAANDNRAAPPGG VAPAENDIGREQPGAETPEPGDPDHQHPHDNDDDDDDDDEHEGEDGETDVDDGDDTSQNRAPRLAGPVYLNDISGCAVLA IAMGELLRNAQDPDGDALSVKNLTVSSGMLVQADEGWLYRGWPTTEGLVTVRYQVTDGEFSVDQVAYFSVSKSFIEGSPA DDLILGTPCADEIDAGCGDDNIDSRGGDDLISAGPGNDHIVAGAGDDVVHAGSGDDIVFGGAGNDHLAGESGNDRLYGQD GDDFLFGDAGDDTLHGGAGRDILHGDDGHDSLKGGEDEDILLAGAGDDTADGGEGADLLDGAEGDDWLQGRAGDDVLLDG PGADKVEGGDGNDRVVPTHDGTADRFDGGKGHDTLDYASTEARVAVDLESGTAKIGESPDDLVSCFDAVVGGAADDELKG SAGGEKLDGGAGDDILDGKGGQDTLLGGAGDDVIADGSGSDVIDAGDGNDRISAAADGDDDHYDGAEGCDTLDYSQTSQG VTVDLKEGLACGEETGRDTIVSMENVIGGTGNDHFIVDHASASLTGGDGEDVFEFCYSPSSPPAETSHLIFDFTVGDRIR MSKYDLFKEVMDEVADHFEDIYGEQSDDEIPIRFSHDWNDEMARTIVEADLNDDAIWETTVYLQGYHVLMIVEQA
Specific function: This adenylate cyclase belongs to a special class of bacterial toxin. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function [H]
COG id: COG2931
COG function: function code Q; RTX toxins and related Ca2+-binding proteins
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 17 hemolysin-type calcium-binding repeats [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005165 - InterPro: IPR018511 - InterPro: IPR001343 - InterPro: IPR018504 - InterPro: IPR003995 - InterPro: IPR011049 [H]
Pfam domain/function: PF03497 Anthrax_toxA; PF00353 HemolysinCabind; PF02382 RTX [H]
EC number: =4.6.1.1 [H]
Molecular weight: Translated: 83511; Mature: 83511
Theoretical pI: Translated: 3.71; Mature: 3.71
Prosite motif: PS00330 HEMOLYSIN_CALCIUM
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIIGVKGTRQKDRQGDPATRYETKNQDQKSNTPYLVGLFLAGIALYLKSMMPLLSRPEKE CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH GTESAKEPVGPTEQQPDLVAESEPEQAPVSEDEDEALPDKLPLGSGEQLADFIPPAQFMQ CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHHHHH IESSAIEFVAFRTPREWNGFFAPPPVSLAANDNRAAPPGGVAPAENDIGREQPGAETPEP HHHCCEEEEEEECCCCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GDPDHQHPHDNDDDDDDDDEHEGEDGETDVDDGDDTSQNRAPRLAGPVYLNDISGCAVLA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHH IAMGELLRNAQDPDGDALSVKNLTVSSGMLVQADEGWLYRGWPTTEGLVTVRYQVTDGEF HHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEECCCEEEECCCCCCCEEEEEEEEECCCC SVDQVAYFSVSKSFIEGSPADDLILGTPCADEIDAGCGDDNIDSRGGDDLISAGPGNDHI CHHHEEEHHHHHHHHCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCCCCEECCCCCCEE VAGAGDDVVHAGSGDDIVFGGAGNDHLAGESGNDRLYGQDGDDFLFGDAGDDTLHGGAGR EECCCCCEEECCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCCCCCCCCC DILHGDDGHDSLKGGEDEDILLAGAGDDTADGGEGADLLDGAEGDDWLQGRAGDDVLLDG CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHCCCCCCCHHHCCCCCCCEEEEC PGADKVEGGDGNDRVVPTHDGTADRFDGGKGHDTLDYASTEARVAVDLESGTAKIGESPD CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHH DLVSCFDAVVGGAADDELKGSAGGEKLDGGAGDDILDGKGGQDTLLGGAGDDVIADGSGS HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCC DVIDAGDGNDRISAAADGDDDHYDGAEGCDTLDYSQTSQGVTVDLKEGLACGEETGRDTI CEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCE VSMENVIGGTGNDHFIVDHASASLTGGDGEDVFEFCYSPSSPPAETSHLIFDFTVGDRIR EEHHHHHCCCCCCCEEEECCCCEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEE MSKYDLFKEVMDEVADHFEDIYGEQSDDEIPIRFSHDWNDEMARTIVEADLNDDAIWETT HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEE VYLQGYHVLMIVEQA EEEECEEEEEEEECC >Mature Secondary Structure MIIGVKGTRQKDRQGDPATRYETKNQDQKSNTPYLVGLFLAGIALYLKSMMPLLSRPEKE CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH GTESAKEPVGPTEQQPDLVAESEPEQAPVSEDEDEALPDKLPLGSGEQLADFIPPAQFMQ CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHHHHH IESSAIEFVAFRTPREWNGFFAPPPVSLAANDNRAAPPGGVAPAENDIGREQPGAETPEP HHHCCEEEEEEECCCCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GDPDHQHPHDNDDDDDDDDEHEGEDGETDVDDGDDTSQNRAPRLAGPVYLNDISGCAVLA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHH IAMGELLRNAQDPDGDALSVKNLTVSSGMLVQADEGWLYRGWPTTEGLVTVRYQVTDGEF HHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEECCCEEEECCCCCCCEEEEEEEEECCCC SVDQVAYFSVSKSFIEGSPADDLILGTPCADEIDAGCGDDNIDSRGGDDLISAGPGNDHI CHHHEEEHHHHHHHHCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCCCCEECCCCCCEE VAGAGDDVVHAGSGDDIVFGGAGNDHLAGESGNDRLYGQDGDDFLFGDAGDDTLHGGAGR EECCCCCEEECCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCCCCCCCCC DILHGDDGHDSLKGGEDEDILLAGAGDDTADGGEGADLLDGAEGDDWLQGRAGDDVLLDG CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHCCCCCCCHHHCCCCCCCEEEEC PGADKVEGGDGNDRVVPTHDGTADRFDGGKGHDTLDYASTEARVAVDLESGTAKIGESPD CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHH DLVSCFDAVVGGAADDELKGSAGGEKLDGGAGDDILDGKGGQDTLLGGAGDDVIADGSGS HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCC DVIDAGDGNDRISAAADGDDDHYDGAEGCDTLDYSQTSQGVTVDLKEGLACGEETGRDTI CEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCE VSMENVIGGTGNDHFIVDHASASLTGGDGEDVFEFCYSPSSPPAETSHLIFDFTVGDRIR EEHHHHHCCCCCCCEEEECCCCEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEE MSKYDLFKEVMDEVADHFEDIYGEQSDDEIPIRFSHDWNDEMARTIVEADLNDDAIWETT HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEE VYLQGYHVLMIVEQA EEEECEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7557410; 12910271 [H]