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The map label for this gene is galE [H]

Identifier: 110633142

GI number: 110633142

Start: 863794

End: 864696

Strand: Reverse

Name: galE [H]

Synonym: Meso_0785

Alternate gene names: 110633142

Gene position: 864696-863794 (Counterclockwise)

Preceding gene: 110633143

Following gene: 110633141

Centisome position: 19.6

GC content: 67.11

Gene sequence:

>903_bases
ATGAAAATTCTGATCACCGGCGGCGGCGGCTTCATCGGAGCCTGGATCGCCAGGAAGCTGCTGGAGGCCGGACACGAAAT
CCGCGTTTTCGACCTTGTCGACGAACGGCGCATCATGCGCCTGATCGCAGGTGGCGCAATCGCGGACGCGATGGATTGGC
GCGTCGGCGATATCGCCGACACGGCAGCGGTTGAGCAGGCCGCGACCGGCTGCGACGGCATCGTCCATCTGGCGGGTCTC
CTGACGCCCGCCTGCCGCGCCAATCCGCTGAAGGGCGTGAGCGTCAACCTCGTCGGCACGCTCAACGTCTTCCTCGCCGC
GCGCAGGCTCGGCATCGCCCGCGTCATCTACATGAGCAGCGCCGGCGTCTTCGGCCCCGACGGCAGCGGCGAACCACGCC
CGGTCACCCATTATGGCAGCTTCAAGCTCGCCTGCGAGAATTCGGCTGCGGCGTTCTGGAATGACGACGGGCTTGCCAGC
GTCGGCTTCAGACCTTTCGTCGTCTATGGTCCTGGCCGCGAGGGCGGACTTTCTGCCGGGCCGACGCTCGCCTGCCGGGC
GGCGGCGAAGGGTGAAGCCTACACGATACCGTTCACCGGCAGCTTCGACATGATCCATGTCGAGGACGTCGCCGCAGCCT
TCGTCATCGCCCTTTCGCTTCCGCCGGCGGGTGCGCGCGTGTTCAACCTGCCCGGCGCCGTAACTTCGTCCGACGAAGTC
GTCGCCGCGATCCTGCGCAGCGTATCCGATGCGCGGATCGATGCCTCCGGCGATCCCATGCCGATAGCCTGCCCGGCGCC
AGACGGGCTGGCACAGGCGGCACTGCCGGGCTGGAAGCCGCGCGATCTCGACAGCGGCATCGCCGATACGATCGCCTTCT
ATCGTCAGCACGCGCAGACCTGA

Upstream 100 bases:

>100_bases
CTGCGTCGCCACCCTTTATGAAACGCAACACGTTTTGACCAATGCGGACGTGGGCCGGGGCTGAACAGCCCTGCCCGCCA
TTGCATCAGCGAGAACCTAA

Downstream 100 bases:

>100_bases
AATCAGGAAAAACCATGTCCGAACGTTTCACAGACCAGACCGCGATCATAACCGGCGGCGTGCGTGGCATCGGCCTCGGC
ATCGCTCGGCGGCTCGCCGA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKILITGGGGFIGAWIARKLLEAGHEIRVFDLVDERRIMRLIAGGAIADAMDWRVGDIADTAAVEQAATGCDGIVHLAGL
LTPACRANPLKGVSVNLVGTLNVFLAARRLGIARVIYMSSAGVFGPDGSGEPRPVTHYGSFKLACENSAAAFWNDDGLAS
VGFRPFVVYGPGREGGLSAGPTLACRAAAKGEAYTIPFTGSFDMIHVEDVAAAFVIALSLPPAGARVFNLPGAVTSSDEV
VAAILRSVSDARIDASGDPMPIACPAPDGLAQAALPGWKPRDLDSGIADTIAFYRQHAQT

Sequences:

>Translated_300_residues
MKILITGGGGFIGAWIARKLLEAGHEIRVFDLVDERRIMRLIAGGAIADAMDWRVGDIADTAAVEQAATGCDGIVHLAGL
LTPACRANPLKGVSVNLVGTLNVFLAARRLGIARVIYMSSAGVFGPDGSGEPRPVTHYGSFKLACENSAAAFWNDDGLAS
VGFRPFVVYGPGREGGLSAGPTLACRAAAKGEAYTIPFTGSFDMIHVEDVAAAFVIALSLPPAGARVFNLPGAVTSSDEV
VAAILRSVSDARIDASGDPMPIACPAPDGLAQAALPGWKPRDLDSGIADTIAFYRQHAQT
>Mature_300_residues
MKILITGGGGFIGAWIARKLLEAGHEIRVFDLVDERRIMRLIAGGAIADAMDWRVGDIADTAAVEQAATGCDGIVHLAGL
LTPACRANPLKGVSVNLVGTLNVFLAARRLGIARVIYMSSAGVFGPDGSGEPRPVTHYGSFKLACENSAAAFWNDDGLAS
VGFRPFVVYGPGREGGLSAGPTLACRAAAKGEAYTIPFTGSFDMIHVEDVAAAFVIALSLPPAGARVFNLPGAVTSSDEV
VAAILRSVSDARIDASGDPMPIACPAPDGLAQAALPGWKPRDLDSGIADTIAFYRQHAQT

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1786974, Length=277, Percent_Identity=27.4368231046931, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 31101; Mature: 31101

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILITGGGGFIGAWIARKLLEAGHEIRVFDLVDERRIMRLIAGGAIADAMDWRVGDIAD
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCHHHHHHCCCCCCHHH
TAAVEQAATGCDGIVHLAGLLTPACRANPLKGVSVNLVGTLNVFLAARRLGIARVIYMSS
HHHHHHHHCCCHHHHHHHHHHCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHEEEEEEEC
AGVFGPDGSGEPRPVTHYGSFKLACENSAAAFWNDDGLASVGFRPFVVYGPGREGGLSAG
CCCCCCCCCCCCCCEEECCCEEEEECCCCCEEECCCCCEECCCCEEEEECCCCCCCCCCC
PTLACRAAAKGEAYTIPFTGSFDMIHVEDVAAAFVIALSLPPAGARVFNLPGAVTSSDEV
CCEEEEECCCCCEEEEEECCCCCEEEHHHHHEEEEEEEECCCCCCEEEECCCCCCCCHHH
VAAILRSVSDARIDASGDPMPIACPAPDGLAQAALPGWKPRDLDSGIADTIAFYRQHAQT
HHHHHHHHHHCEECCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILITGGGGFIGAWIARKLLEAGHEIRVFDLVDERRIMRLIAGGAIADAMDWRVGDIAD
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCHHHHHHCCCCCCHHH
TAAVEQAATGCDGIVHLAGLLTPACRANPLKGVSVNLVGTLNVFLAARRLGIARVIYMSS
HHHHHHHHCCCHHHHHHHHHHCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHEEEEEEEC
AGVFGPDGSGEPRPVTHYGSFKLACENSAAAFWNDDGLASVGFRPFVVYGPGREGGLSAG
CCCCCCCCCCCCCCEEECCCEEEEECCCCCEEECCCCCEECCCCEEEEECCCCCCCCCCC
PTLACRAAAKGEAYTIPFTGSFDMIHVEDVAAAFVIALSLPPAGARVFNLPGAVTSSDEV
CCEEEEECCCCCEEEEEECCCCCEEEHHHHHEEEEEEEECCCCCCEEEECCCCCCCCHHH
VAAILRSVSDARIDASGDPMPIACPAPDGLAQAALPGWKPRDLDSGIADTIAFYRQHAQT
HHHHHHHHHHCEECCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]