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The map label for this gene is exoB [H]

Identifier: 110633134

GI number: 110633134

Start: 853318

End: 854307

Strand: Direct

Name: exoB [H]

Synonym: Meso_0777

Alternate gene names: 110633134

Gene position: 853318-854307 (Clockwise)

Preceding gene: 110633133

Following gene: 110633137

Centisome position: 19.34

GC content: 62.73

Gene sequence:

>990_bases
GTGACGGTTCTGGTAACGGGCGGCGCCGGCTATATCGGCAGCCACATGGTATGGGAACTGCTGGACCATGGCGAAGAGGT
GGTGGTGCTCGACCGGCTCTCCACCGGTTTCGATTGGGCTGTGCCCGAAGCCGCCGAACTCGTCGTGGGCGATATCGGCG
ACCAGGCGCTGCTGGAAGAAACGATAAAGCGCCGCAACGTGGATGCGGTGATCCATTTCGCGGGCTCGATCATCGTGCCG
GAATCCGTGGCCGATCCGCTGGGCTATTACCTCAACAATACCGTCAAGTCGCGGGCTCTCATCGAAAGCGCCGTCCGGTG
CGGCGTCAAGCATTTCATCTTTTCCTCGACTGCGGCGGTCTACGGCACGCCGCGAAAGAACCCGGTCACCGAGGACGAAC
CCTTGCTGCCGGAATCGCCTTACGGCACATCCAAGCTGATGACGGAGATCATGCTGCGCGATACGGCGGCGGCCCATGAT
TTCGCCTATACGGCTTTGCGCTACTTCAACGTCTCGGGAGCGGACCCGAAGCGCCGGACGGGACAGTCCACGAAGGGAGC
AACCCATCTCATCAAGGTGGCCTGCGAGACCGCCACGGGGAAGCGGGCCTCCATGGAGGTATTCGGTACCGATTATCCCA
CGCCTGACGGCACCTGCGTGCGCGATTACATCCATGTCTCGGATCTGGTGAACGCACACTATCTGGCGCTGCAGCGCCTG
CGGAGCGGAGGCGGCAGCCTGGTTGCCAATTGCGGCTATGGCAGGGGTTATTCCGTGCTTGAGGTCATTGATGCGGTGAA
GCAGGTTTCCGGCAAGGACTTCAAGGTGGTCGAGAGCGGCAGGCGGCCCGGCGATGCCGTCGCCATTGTGGCGAGCGCGG
AGCGCTGCTTCGCCGAACTCGGCTGGCGTCCCGAGCACGACGATCTCCGGGAGATCGTCAGCGACGCTCTCCGTTGGGAA
GAGATCCTGGCTAAGCGCAACCGGGTGTGA

Upstream 100 bases:

>100_bases
CTCCTCCGCTGATAGCGGGTCTTGCCTCGTCTCGAACGGATATGAAACAGTTATGGGCGAGGAAACTCGCCCATTCTTTT
TTGAAGCTGAGGACTGAGAC

Downstream 100 bases:

>100_bases
GGGCTGAAGGCCGCTGGCGATAGACATCTGTTCGCTCATGCGCCCTGCGCACCCCCCTCTGGCCTGCCGGCCATCTCCCC
CACAAGGGGGGAGATCGGCT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTVLVTGGAGYIGSHMVWELLDHGEEVVVLDRLSTGFDWAVPEAAELVVGDIGDQALLEETIKRRNVDAVIHFAGSIIVP
ESVADPLGYYLNNTVKSRALIESAVRCGVKHFIFSSTAAVYGTPRKNPVTEDEPLLPESPYGTSKLMTEIMLRDTAAAHD
FAYTALRYFNVSGADPKRRTGQSTKGATHLIKVACETATGKRASMEVFGTDYPTPDGTCVRDYIHVSDLVNAHYLALQRL
RSGGGSLVANCGYGRGYSVLEVIDAVKQVSGKDFKVVESGRRPGDAVAIVASAERCFAELGWRPEHDDLREIVSDALRWE
EILAKRNRV

Sequences:

>Translated_329_residues
MTVLVTGGAGYIGSHMVWELLDHGEEVVVLDRLSTGFDWAVPEAAELVVGDIGDQALLEETIKRRNVDAVIHFAGSIIVP
ESVADPLGYYLNNTVKSRALIESAVRCGVKHFIFSSTAAVYGTPRKNPVTEDEPLLPESPYGTSKLMTEIMLRDTAAAHD
FAYTALRYFNVSGADPKRRTGQSTKGATHLIKVACETATGKRASMEVFGTDYPTPDGTCVRDYIHVSDLVNAHYLALQRL
RSGGGSLVANCGYGRGYSVLEVIDAVKQVSGKDFKVVESGRRPGDAVAIVASAERCFAELGWRPEHDDLREIVSDALRWE
EILAKRNRV
>Mature_328_residues
TVLVTGGAGYIGSHMVWELLDHGEEVVVLDRLSTGFDWAVPEAAELVVGDIGDQALLEETIKRRNVDAVIHFAGSIIVPE
SVADPLGYYLNNTVKSRALIESAVRCGVKHFIFSSTAAVYGTPRKNPVTEDEPLLPESPYGTSKLMTEIMLRDTAAAHDF
AYTALRYFNVSGADPKRRTGQSTKGATHLIKVACETATGKRASMEVFGTDYPTPDGTCVRDYIHVSDLVNAHYLALQRLR
SGGGSLVANCGYGRGYSVLEVIDAVKQVSGKDFKVVESGRRPGDAVAIVASAERCFAELGWRPEHDDLREIVSDALRWEE
ILAKRNRV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=40.7738095238095, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=40.7738095238095, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=40.7738095238095, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI42516563, Length=312, Percent_Identity=25.6410256410256, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7657641, Length=334, Percent_Identity=24.8502994011976, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1786974, Length=330, Percent_Identity=42.1212121212121, Blast_Score=234, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=38.0530973451327, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=37.8299120234604, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17568069, Length=249, Percent_Identity=29.718875502008, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=314, Percent_Identity=22.9299363057325, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=38.2089552238806, Blast_Score=199, Evalue=5e-52,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=38.5756676557863, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=25.2396166134185, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35858; Mature: 35727

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVTGGAGYIGSHMVWELLDHGEEVVVLDRLSTGFDWAVPEAAELVVGDIGDQALLEE
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHH
TIKRRNVDAVIHFAGSIIVPESVADPLGYYLNNTVKSRALIESAVRCGVKHFIFSSTAAV
HHHHCCHHHEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
YGTPRKNPVTEDEPLLPESPYGTSKLMTEIMLRDTAAAHDFAYTALRYFNVSGADPKRRT
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
GQSTKGATHLIKVACETATGKRASMEVFGTDYPTPDGTCVRDYIHVSDLVNAHYLALQRL
CCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RSGGGSLVANCGYGRGYSVLEVIDAVKQVSGKDFKVVESGRRPGDAVAIVASAERCFAEL
HCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHCCCCCCCEEEEEEHHHHHHHHC
GWRPEHDDLREIVSDALRWEEILAKRNRV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVLVTGGAGYIGSHMVWELLDHGEEVVVLDRLSTGFDWAVPEAAELVVGDIGDQALLEE
EEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHH
TIKRRNVDAVIHFAGSIIVPESVADPLGYYLNNTVKSRALIESAVRCGVKHFIFSSTAAV
HHHHCCHHHEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
YGTPRKNPVTEDEPLLPESPYGTSKLMTEIMLRDTAAAHDFAYTALRYFNVSGADPKRRT
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
GQSTKGATHLIKVACETATGKRASMEVFGTDYPTPDGTCVRDYIHVSDLVNAHYLALQRL
CCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RSGGGSLVANCGYGRGYSVLEVIDAVKQVSGKDFKVVESGRRPGDAVAIVASAERCFAEL
HCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHCCCCCCCEEEEEEHHHHHHHHC
GWRPEHDDLREIVSDALRWEEILAKRNRV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]