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The map label for this gene is ppdK [H]

Identifier: 110633129

GI number: 110633129

Start: 847610

End: 850273

Strand: Direct

Name: ppdK [H]

Synonym: Meso_0772

Alternate gene names: 110633129

Gene position: 847610-850273 (Clockwise)

Preceding gene: 110633127

Following gene: 110633131

Centisome position: 19.21

GC content: 64.04

Gene sequence:

>2664_bases
ATGACCAAATGGGTCTACAGCTTTGGCGACGGTAAGGCCGAGGGCAGGGCCTCGGACAGGAATCTTCTGGGCGGCAAGGG
CGCCAATCTGGCCGAGATGTGCAGTCTGGGCCTGCCGGTTCCGCCGGGCTTTACCATCACGACCGAAGTCTGCACCCATT
ATTATGCCAATGGCCGCGCCTATCCTGCCGAATTGGAAGCGCAGGTTAACGCGGCATTGGACGAGGTGGGCCGCATCGCC
GGCCGCCGGTTCGGAGATCCCGACCGGCTGCTCCTGGTTTCCGTGCGTTCCGGCGCGCGCGCGTCCATGCCGGGCATGAT
GGATACCGTGCTCAATCTCGGCCTCAATGACGAGACGGTGGGGGCGCTGGCGGCTGAATCCAGTGACGAGCGCTTCGCCT
ATGACAGCTACCGCCGCTTCATCCAGATGTATGGCAATGTGGTGCTGGACGTGGAGCATGAGGTTTTCGAGGAAATCCTT
GCCGACGAGAAAGCGCGGCGCGGCTATGACGTGGATACGGATTTTACCGCCGCGGATTGGAAGGAGGTTGTGGATCTCTA
CAAGGAGAAGGTTGAGAGCGAGCTTGGAAGGCCCTTTCCGCAGGACCCGCACGAGCAGCTCTGGGGTGCGATCAGCGCCG
TCTTCTCGAGCTGGATGAATCCGCGCGCCATCACCTATCGCCGGCTGCACGATATTCCGGAAAGCTGGGGCACGGCGGTG
AACGTCCAAGCCATGGTTTTCGGCAATATGGGCCAGACTTCCGCCACGGGCGTGGCCTTTACGCGCAATCCTTCGACGGG
CGAGAAGGCGCTTTACGGCGAATTTCTTGTGAATGCCCAGGGCGAGGACGTGGTGGCCGGAATCCGCACCCCGCAATGCC
TGACCGAGGCGGCGCGCCGCGAGGCGGGCTCCGATAAGCCCTCGCTCGAAAAGGTCATGCCGCAGGCATTCGCGGCTTTC
GTCGATATCGCGGAAAAGCTGGAGCAGCATTACCGCGACATGCAGGACCTGGAATTCACCATCGAGCGCGGCAAGCTCTG
GATGCTGCAAACCCGTTCCGGCAAGCGCACCACCAAGGCAGCGCTCAAGATCGCCGTGGACATGGCCAATGAGGGCCTGA
TTTCCAAGGCCGAGGCCATCTGCCGCATCGACCCGGCCTCGCTCGACCAGCTTCTTCACCCCACCATCGATCCGAGCGCC
AAACGCGACGCCATCGCGGTGGGTCTGCCCGCCTCTCCCGGCGCGGCCACGGGCGAGATCGTCTTTTCCCCCGACGAGGC
GGAGGAGATGGCGGGGCGGGGAAAGAAGGTGATCCTCGTCCGCGTGGAAACCAGCCCCGACGACATTCACGGCATGCACG
CCGCTCAAGGGATTCTCACGACCCGCGGCGGCATGACGAGCCATGCCGCGGTGGTCGCGCGCGGCATGGGAAAGCCCTGC
GTGTCCGGCGCGGGCACGCTCAGGGTCGATACGCGTGCCGGGACGATGGTCTCCATGGGCCGCAGCTTTCAGCGTGGCGA
CGTCATCACCATTGACGGGTCCACCGGCCAGGTGCTCGTAGGGGCGGTGCCCATGCAGCAGCCCGAGCTCTCGGGCGATT
TCTCCACCCTGATGGGCTGGGCGGACGAATTGCGCCGCATGAAGGTGCGCTCCAATGCCGAGACACCCGCCGATGCGCGC
ACCGCGCGCTCCTTCGGTGCCGAGGGTATCGGCCTTTGCCGGACCGAGCACATGTTCTTCGACGGCGACCGCATTCTTGC
CATGCGCGAGATGATCTTGTCGGACACGGAGGAGCAGAGGCGCGCGGCGCTTGCCAAGCTCTTGCCGATGCAGCGGGCGG
ATTTCACGGAACTGTTTGAAATCATGGCGGGCCTGCCCGTTACGATCAGGCTGCTCGATCCGCCTCTGCATGAGTTCCTT
CCGCATGGTGAGGCGGAAATCGGCGAAGTCGCGGCGGCGATGGGCGTCGACCGGGAAAAGCTTCGCCAGAAGGCCGAAAG
CCTGCACGAGTTCAATCCGATGCTCGGCCACCGGGGCTGCCGTCTTGCGATCTCCTATCCAGAGATTGCGGAAATGCAGG
CCCGGGCCATCTTCGAGGCAGCGGTTGATGCGGCTGAGAAGAGCGGCTCGCCGGTGGTGCCGGAGATCATGGTGCCTCTC
GTCGGCATCTCCTCCGAGCTCTCATTCGTGAAGGCGATCATCGATGATGTGGCCAAAAAGGTTCAGGCCGAGCGGGGCGC
GGCGATCGAATATCTCGTCGGCACGATGATCGAGCTGCCGCGCGCCGCGCTAAACGCGGGCGAGATCGCGCGTGAGGCGG
AGTTCTTCTCCTTCGGCACGAATGATCTGACGCAGACCACCTTCGGCATCTCGCGCGACGATGCTGCTGGCTTTCTGGAG
GTCTATCGCAAGAAGGGCTTGATCGAGCACGATCCCTTCGTAACGCTCGATGTGGACGGTGTCGGCGCACTGGTGAGAAT
CGCTGCGGAGAAGGGTGGGGCGGCCCGCAAGGGCATCAAGCTCGGAATCTGCGGCGAACATGGCGGCGATCCAGCCTCGA
TCGCCTTTTGCGAAGAAGTCGGCCTGGACTACGTGTCCTGCTCGCCCTTCCGCGTGCCGATCGCGCGCCTGGCGGCGGCT
CAGGCCGCCTGCCGCAAGGGGTAG

Upstream 100 bases:

>100_bases
AGTAGACACAGAGCTGCCGGCGATGCCTTGCCAGATTTGCCGGTGGCCGCTACCGCTCTTGTTGCGGTGCGGTATGCCGC
GAAATTCACCAGGGGGTGTC

Downstream 100 bases:

>100_bases
GAACGGGAAGTCAGGAAAGCCTGCCGAGGCTTTTCACCAGATTAGCATAGGCGGTGGCGACACGGGCGATGGAGGTATCG
CTTGTTTCGGCGTCTTCGAC

Product: pyruvate phosphate dikinase

Products: NA

Alternate protein names: Pyruvate, orthophosphate dikinase [H]

Number of amino acids: Translated: 887; Mature: 886

Protein sequence:

>887_residues
MTKWVYSFGDGKAEGRASDRNLLGGKGANLAEMCSLGLPVPPGFTITTEVCTHYYANGRAYPAELEAQVNAALDEVGRIA
GRRFGDPDRLLLVSVRSGARASMPGMMDTVLNLGLNDETVGALAAESSDERFAYDSYRRFIQMYGNVVLDVEHEVFEEIL
ADEKARRGYDVDTDFTAADWKEVVDLYKEKVESELGRPFPQDPHEQLWGAISAVFSSWMNPRAITYRRLHDIPESWGTAV
NVQAMVFGNMGQTSATGVAFTRNPSTGEKALYGEFLVNAQGEDVVAGIRTPQCLTEAARREAGSDKPSLEKVMPQAFAAF
VDIAEKLEQHYRDMQDLEFTIERGKLWMLQTRSGKRTTKAALKIAVDMANEGLISKAEAICRIDPASLDQLLHPTIDPSA
KRDAIAVGLPASPGAATGEIVFSPDEAEEMAGRGKKVILVRVETSPDDIHGMHAAQGILTTRGGMTSHAAVVARGMGKPC
VSGAGTLRVDTRAGTMVSMGRSFQRGDVITIDGSTGQVLVGAVPMQQPELSGDFSTLMGWADELRRMKVRSNAETPADAR
TARSFGAEGIGLCRTEHMFFDGDRILAMREMILSDTEEQRRAALAKLLPMQRADFTELFEIMAGLPVTIRLLDPPLHEFL
PHGEAEIGEVAAAMGVDREKLRQKAESLHEFNPMLGHRGCRLAISYPEIAEMQARAIFEAAVDAAEKSGSPVVPEIMVPL
VGISSELSFVKAIIDDVAKKVQAERGAAIEYLVGTMIELPRAALNAGEIAREAEFFSFGTNDLTQTTFGISRDDAAGFLE
VYRKKGLIEHDPFVTLDVDGVGALVRIAAEKGGAARKGIKLGICGEHGGDPASIAFCEEVGLDYVSCSPFRVPIARLAAA
QAACRKG

Sequences:

>Translated_887_residues
MTKWVYSFGDGKAEGRASDRNLLGGKGANLAEMCSLGLPVPPGFTITTEVCTHYYANGRAYPAELEAQVNAALDEVGRIA
GRRFGDPDRLLLVSVRSGARASMPGMMDTVLNLGLNDETVGALAAESSDERFAYDSYRRFIQMYGNVVLDVEHEVFEEIL
ADEKARRGYDVDTDFTAADWKEVVDLYKEKVESELGRPFPQDPHEQLWGAISAVFSSWMNPRAITYRRLHDIPESWGTAV
NVQAMVFGNMGQTSATGVAFTRNPSTGEKALYGEFLVNAQGEDVVAGIRTPQCLTEAARREAGSDKPSLEKVMPQAFAAF
VDIAEKLEQHYRDMQDLEFTIERGKLWMLQTRSGKRTTKAALKIAVDMANEGLISKAEAICRIDPASLDQLLHPTIDPSA
KRDAIAVGLPASPGAATGEIVFSPDEAEEMAGRGKKVILVRVETSPDDIHGMHAAQGILTTRGGMTSHAAVVARGMGKPC
VSGAGTLRVDTRAGTMVSMGRSFQRGDVITIDGSTGQVLVGAVPMQQPELSGDFSTLMGWADELRRMKVRSNAETPADAR
TARSFGAEGIGLCRTEHMFFDGDRILAMREMILSDTEEQRRAALAKLLPMQRADFTELFEIMAGLPVTIRLLDPPLHEFL
PHGEAEIGEVAAAMGVDREKLRQKAESLHEFNPMLGHRGCRLAISYPEIAEMQARAIFEAAVDAAEKSGSPVVPEIMVPL
VGISSELSFVKAIIDDVAKKVQAERGAAIEYLVGTMIELPRAALNAGEIAREAEFFSFGTNDLTQTTFGISRDDAAGFLE
VYRKKGLIEHDPFVTLDVDGVGALVRIAAEKGGAARKGIKLGICGEHGGDPASIAFCEEVGLDYVSCSPFRVPIARLAAA
QAACRKG
>Mature_886_residues
TKWVYSFGDGKAEGRASDRNLLGGKGANLAEMCSLGLPVPPGFTITTEVCTHYYANGRAYPAELEAQVNAALDEVGRIAG
RRFGDPDRLLLVSVRSGARASMPGMMDTVLNLGLNDETVGALAAESSDERFAYDSYRRFIQMYGNVVLDVEHEVFEEILA
DEKARRGYDVDTDFTAADWKEVVDLYKEKVESELGRPFPQDPHEQLWGAISAVFSSWMNPRAITYRRLHDIPESWGTAVN
VQAMVFGNMGQTSATGVAFTRNPSTGEKALYGEFLVNAQGEDVVAGIRTPQCLTEAARREAGSDKPSLEKVMPQAFAAFV
DIAEKLEQHYRDMQDLEFTIERGKLWMLQTRSGKRTTKAALKIAVDMANEGLISKAEAICRIDPASLDQLLHPTIDPSAK
RDAIAVGLPASPGAATGEIVFSPDEAEEMAGRGKKVILVRVETSPDDIHGMHAAQGILTTRGGMTSHAAVVARGMGKPCV
SGAGTLRVDTRAGTMVSMGRSFQRGDVITIDGSTGQVLVGAVPMQQPELSGDFSTLMGWADELRRMKVRSNAETPADART
ARSFGAEGIGLCRTEHMFFDGDRILAMREMILSDTEEQRRAALAKLLPMQRADFTELFEIMAGLPVTIRLLDPPLHEFLP
HGEAEIGEVAAAMGVDREKLRQKAESLHEFNPMLGHRGCRLAISYPEIAEMQARAIFEAAVDAAEKSGSPVVPEIMVPLV
GISSELSFVKAIIDDVAKKVQAERGAAIEYLVGTMIELPRAALNAGEIAREAEFFSFGTNDLTQTTFGISRDDAAGFLEV
YRKKGLIEHDPFVTLDVDGVGALVRIAAEKGGAARKGIKLGICGEHGGDPASIAFCEEVGLDYVSCSPFRVPIARLAAAQ
AACRKG

Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1788756, Length=455, Percent_Identity=25.9340659340659, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1787994, Length=714, Percent_Identity=25.3501400560224, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789193, Length=426, Percent_Identity=26.2910798122066, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI48994992, Length=450, Percent_Identity=26, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788726, Length=459, Percent_Identity=22.4400871459695, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR010121
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.1 [H]

Molecular weight: Translated: 95971; Mature: 95840

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKWVYSFGDGKAEGRASDRNLLGGKGANLAEMCSLGLPVPPGFTITTEVCTHYYANGRA
CCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCC
YPAELEAQVNAALDEVGRIAGRRFGDPDRLLLVSVRSGARASMPGMMDTVLNLGLNDETV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHH
GALAAESSDERFAYDSYRRFIQMYGNVVLDVEHEVFEEILADEKARRGYDVDTDFTAADW
HHHCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHHHH
KEVVDLYKEKVESELGRPFPQDPHEQLWGAISAVFSSWMNPRAITYRRLHDIPESWGTAV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHCCEE
NVQAMVFGNMGQTSATGVAFTRNPSTGEKALYGEFLVNAQGEDVVAGIRTPQCLTEAARR
EEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHEECCCCCCEEECCCCHHHHHHHHHH
EAGSDKPSLEKVMPQAFAAFVDIAEKLEQHYRDMQDLEFTIERGKLWMLQTRSGKRTTKA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCEEEEEECCCCHHHHH
ALKIAVDMANEGLISKAEAICRIDPASLDQLLHPTIDPSAKRDAIAVGLPASPGAATGEI
HHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCE
VFSPDEAEEMAGRGKKVILVRVETSPDDIHGMHAAQGILTTRGGMTSHAAVVARGMGKPC
EECCCHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHEECCCCCHHHHHHHHCCCCCC
VSGAGTLRVDTRAGTMVSMGRSFQRGDVITIDGSTGQVLVGAVPMQQPELSGDFSTLMGW
CCCCCEEEEECCCCHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHH
ADELRRMKVRSNAETPADARTARSFGAEGIGLCRTEHMFFDGDRILAMREMILSDTEEQR
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCEEECCCHHHHHHHHHHCCCHHHH
RAALAKLLPMQRADFTELFEIMAGLPVTIRLLDPPLHEFLPHGEAEIGEVAAAMGVDREK
HHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHCCCHHH
LRQKAESLHEFNPMLGHRGCRLAISYPEIAEMQARAIFEAAVDAAEKSGSPVVPEIMVPL
HHHHHHHHHHHCHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VGISSELSFVKAIIDDVAKKVQAERGAAIEYLVGTMIELPRAALNAGEIAREAEFFSFGT
HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
NDLTQTTFGISRDDAAGFLEVYRKKGLIEHDPFVTLDVDGVGALVRIAAEKGGAARKGIK
CCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHEEHHCCCCCCCCCE
LGICGEHGGDPASIAFCEEVGLDYVSCSPFRVPIARLAAAQAACRKG
EEECCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKWVYSFGDGKAEGRASDRNLLGGKGANLAEMCSLGLPVPPGFTITTEVCTHYYANGRA
CCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCC
YPAELEAQVNAALDEVGRIAGRRFGDPDRLLLVSVRSGARASMPGMMDTVLNLGLNDETV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHH
GALAAESSDERFAYDSYRRFIQMYGNVVLDVEHEVFEEILADEKARRGYDVDTDFTAADW
HHHCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHHHH
KEVVDLYKEKVESELGRPFPQDPHEQLWGAISAVFSSWMNPRAITYRRLHDIPESWGTAV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHCCEE
NVQAMVFGNMGQTSATGVAFTRNPSTGEKALYGEFLVNAQGEDVVAGIRTPQCLTEAARR
EEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHEECCCCCCEEECCCCHHHHHHHHHH
EAGSDKPSLEKVMPQAFAAFVDIAEKLEQHYRDMQDLEFTIERGKLWMLQTRSGKRTTKA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCEEEEEECCCCHHHHH
ALKIAVDMANEGLISKAEAICRIDPASLDQLLHPTIDPSAKRDAIAVGLPASPGAATGEI
HHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCE
VFSPDEAEEMAGRGKKVILVRVETSPDDIHGMHAAQGILTTRGGMTSHAAVVARGMGKPC
EECCCHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHEECCCCCHHHHHHHHCCCCCC
VSGAGTLRVDTRAGTMVSMGRSFQRGDVITIDGSTGQVLVGAVPMQQPELSGDFSTLMGW
CCCCCEEEEECCCCHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHH
ADELRRMKVRSNAETPADARTARSFGAEGIGLCRTEHMFFDGDRILAMREMILSDTEEQR
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCEEECCCHHHHHHHHHHCCCHHHH
RAALAKLLPMQRADFTELFEIMAGLPVTIRLLDPPLHEFLPHGEAEIGEVAAAMGVDREK
HHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHCCCHHH
LRQKAESLHEFNPMLGHRGCRLAISYPEIAEMQARAIFEAAVDAAEKSGSPVVPEIMVPL
HHHHHHHHHHHCHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VGISSELSFVKAIIDDVAKKVQAERGAAIEYLVGTMIELPRAALNAGEIAREAEFFSFGT
HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
NDLTQTTFGISRDDAAGFLEVYRKKGLIEHDPFVTLDVDGVGALVRIAAEKGGAARKGIK
CCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHEEHHCCCCCCCCCE
LGICGEHGGDPASIAFCEEVGLDYVSCSPFRVPIARLAAAQAACRKG
EEECCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9168612 [H]