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The map label for this gene is ubiA [H]

Identifier: 110633075

GI number: 110633075

Start: 793553

End: 794536

Strand: Reverse

Name: ubiA [H]

Synonym: Meso_0718

Alternate gene names: 110633075

Gene position: 794536-793553 (Counterclockwise)

Preceding gene: 110633079

Following gene: 110633067

Centisome position: 18.01

GC content: 64.53

Gene sequence:

>984_bases
ATGGATATCATCCAGTCCCGGCGGATGCGGGGCCGCGTCGCCGATGCACCGTCGGGCCATTGGGTTTATCGCCTTTTGCC
GCGCGGCGCCTGGCCTTATGCCCAGCTTGCCCGCTGGGACCGCCCTATCGGCTGGAAACTTCTGCTATGGCCGTGCTGGT
GGTCGCTCGCCCTGGCGTCAGCCGCGGGCGCCACGCCCGGCACGCCGCTTCTGGACGTCATTCCGTCGCTCTGGCACCTC
CTGCTTTTCCTCCTGGGCGCCATTGCGATGCGCGGTGCTGGCTGCACCTATAACGATATCGTTGACCTGGATGTGGACGA
GAAGGTGGAGCGGACGCGCTCGCGCCCGCTGCCTTCGGGCCAGGTTTCCCGAAAGCAGGCCTGGGCGTTTCTCGTGGCGC
AGGCGCTCGTCGGCCTTGCGGTGCTCCTGCAGTTCAACGGCTTTGCCATCCTGGTGGGGCTGGCATCGCTCCTGACGGTG
GCGGTCTATCCCTTCGCGAAAAGATTCACCGACTGGCCGCAATTCTTTCTGGGGCTTGCGTTTTCCTGGGGCGCCCTGAT
GGGCTGGGCCGTCCATTTCGGTGCCCTGTCGCTCGCCGCTTTCCTGCTCTACTGCGGCAGCATTCTGTGGGTGATCGGTT
ACGACACGATCTATGCCCATCAGGACAAGGAGGACGATGCGCTGGTAGGCGTCCGCTCAACCGCGCGCCTCTTTGGCGAG
CATACGAAACGCTGGCTTGTTGCGCTCTACGGGGGAGCGCTCCTCTTTTTCGCCGTCGCCTTTGCACTTGCGGCCGTGCC
TATGCCGGCGCTTGCCGGACTTGTTGCCGCCGGCGCACATATGTCGCGGCAGATCCGGGTGCTCGACATCGACGACCCGG
ACCAGTGCCTTGCCCTTTTCAAGTCCAACTCGGTTGTGGGCTGGCTGATCTTCCTGGGGCTCCTGGGCGGAGGCGCCTGG
GCGACGATCAGCCCTTATTTCTGA

Upstream 100 bases:

>100_bases
AGGTCAAGCCGCAGCGAGACATATCAAGAAGGATTGGCTTGACGCGGGCCGCCCCTCTTGCCACTCCACTCAAACCATCG
AAATGGGAAAGAGAGGGCAG

Downstream 100 bases:

>100_bases
TGTAGAGACAATCAGCCGCGGGCGGTGATCTCCTCGCCATCAACAACCAGACGCAGGCCGAGCGAGCCCTTGCGGCGGCG
AGCCAGGAAGCGCGGACGGC

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDIIQSRRMRGRVADAPSGHWVYRLLPRGAWPYAQLARWDRPIGWKLLLWPCWWSLALASAAGATPGTPLLDVIPSLWHL
LLFLLGAIAMRGAGCTYNDIVDLDVDEKVERTRSRPLPSGQVSRKQAWAFLVAQALVGLAVLLQFNGFAILVGLASLLTV
AVYPFAKRFTDWPQFFLGLAFSWGALMGWAVHFGALSLAAFLLYCGSILWVIGYDTIYAHQDKEDDALVGVRSTARLFGE
HTKRWLVALYGGALLFFAVAFALAAVPMPALAGLVAAGAHMSRQIRVLDIDDPDQCLALFKSNSVVGWLIFLGLLGGGAW
ATISPYF

Sequences:

>Translated_327_residues
MDIIQSRRMRGRVADAPSGHWVYRLLPRGAWPYAQLARWDRPIGWKLLLWPCWWSLALASAAGATPGTPLLDVIPSLWHL
LLFLLGAIAMRGAGCTYNDIVDLDVDEKVERTRSRPLPSGQVSRKQAWAFLVAQALVGLAVLLQFNGFAILVGLASLLTV
AVYPFAKRFTDWPQFFLGLAFSWGALMGWAVHFGALSLAAFLLYCGSILWVIGYDTIYAHQDKEDDALVGVRSTARLFGE
HTKRWLVALYGGALLFFAVAFALAAVPMPALAGLVAAGAHMSRQIRVLDIDDPDQCLALFKSNSVVGWLIFLGLLGGGAW
ATISPYF
>Mature_327_residues
MDIIQSRRMRGRVADAPSGHWVYRLLPRGAWPYAQLARWDRPIGWKLLLWPCWWSLALASAAGATPGTPLLDVIPSLWHL
LLFLLGAIAMRGAGCTYNDIVDLDVDEKVERTRSRPLPSGQVSRKQAWAFLVAQALVGLAVLLQFNGFAILVGLASLLTV
AVYPFAKRFTDWPQFFLGLAFSWGALMGWAVHFGALSLAAFLLYCGSILWVIGYDTIYAHQDKEDDALVGVRSTARLFGE
HTKRWLVALYGGALLFFAVAFALAAVPMPALAGLVAAGAHMSRQIRVLDIDDPDQCLALFKSNSVVGWLIFLGLLGGGAW
ATISPYF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=296, Percent_Identity=44.5945945945946, Blast_Score=234, Evalue=7e-62,
Organism=Escherichia coli, GI1790473, Length=282, Percent_Identity=38.2978723404255, Blast_Score=174, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17553718, Length=290, Percent_Identity=44.8275862068966, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI32565247, Length=292, Percent_Identity=43.1506849315069, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17553720, Length=353, Percent_Identity=34.8441926345609, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI32565245, Length=152, Percent_Identity=48.6842105263158, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32565243, Length=151, Percent_Identity=48.3443708609272, Blast_Score=121, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324370, Length=293, Percent_Identity=39.5904436860068, Blast_Score=172, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21355567, Length=293, Percent_Identity=49.8293515358362, Blast_Score=257, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 35860; Mature: 35860

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIQSRRMRGRVADAPSGHWVYRLLPRGAWPYAQLARWDRPIGWKLLLWPCWWSLALAS
CCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHH
AAGATPGTPLLDVIPSLWHLLLFLLGAIAMRGAGCTYNDIVDLDVDEKVERTRSRPLPSG
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCCCCC
QVSRKQAWAFLVAQALVGLAVLLQFNGFAILVGLASLLTVAVYPFAKRFTDWPQFFLGLA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FSWGALMGWAVHFGALSLAAFLLYCGSILWVIGYDTIYAHQDKEDDALVGVRSTARLFGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHEEHHHHHHHHHH
HTKRWLVALYGGALLFFAVAFALAAVPMPALAGLVAAGAHMSRQIRVLDIDDPDQCLALF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHH
KSNSVVGWLIFLGLLGGGAWATISPYF
HCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDIIQSRRMRGRVADAPSGHWVYRLLPRGAWPYAQLARWDRPIGWKLLLWPCWWSLALAS
CCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHH
AAGATPGTPLLDVIPSLWHLLLFLLGAIAMRGAGCTYNDIVDLDVDEKVERTRSRPLPSG
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCCCCC
QVSRKQAWAFLVAQALVGLAVLLQFNGFAILVGLASLLTVAVYPFAKRFTDWPQFFLGLA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FSWGALMGWAVHFGALSLAAFLLYCGSILWVIGYDTIYAHQDKEDDALVGVRSTARLFGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHEEHHHHHHHHHH
HTKRWLVALYGGALLFFAVAFALAAVPMPALAGLVAAGAHMSRQIRVLDIDDPDQCLALF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHH
KSNSVVGWLIFLGLLGGGAWATISPYF
HCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA