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The map label for this gene is prpE [H]

Identifier: 110633018

GI number: 110633018

Start: 739914

End: 740663

Strand: Reverse

Name: prpE [H]

Synonym: Meso_0661

Alternate gene names: 110633018

Gene position: 740663-739914 (Counterclockwise)

Preceding gene: 110633019

Following gene: 110633010

Centisome position: 16.79

GC content: 60.93

Gene sequence:

>750_bases
TTGCTGGGCGGAGGCAAGCATGGCGCCGCACGCGCGCGCCTGCGCATCGATCTTCGCGACACAATCGTCTACGCCATCGG
CGATGTTCACGGCTGCTTCAAGGAATTGGAGCGGCTGGAGCAGAAGATCGCCGACGACGCGTCAGGCTTCAGCGGCCGCA
AGCTCATCATAATGCTGGGGGATTATGTGGACCGTGGACCGGATTCGGCTCAGGTCGTCGAGCATCTCCTACAGAACCCA
CCGGAAGGTTTTCAGCGCATCTGCCTGGCAGGCAATCACGAAAAATCCTTTCTTGATTATCTGGACGGCGTTCTGGCCCG
CGAGGCCTGGCTTGCCACCGGCGGCGGGACCACGCTCCGCTCCTATGGGATCGATCTTTCCTATCTCGCCAATCTCTATT
CGGCTTCGGAGATCGACCAGATGGTGCGCTCAAGCATTCCGCCCGCACATGTGGAGTTCTTGCGTGCGCTGCCCGTTATG
GCCTATTCGCGCCAGGTGGTGTTCGTTCACGCAGGCATCCGGCCCGGGATCCCGCTTCGGGATCAGCATGAACGCGACCT
CATGTTCATCCGCAAGGAGTTTTTCGATCATGCCGGCCAACTGGACCGATGGGTGATTCACGGCCATACGCCGGTAAAGA
AACCGGACCTCAGCGGCCGCAGGCTCAACATCGATACCGGCGCCTATATGAGCGGCCGGCTGACCGCCGTGCAGATCGGC
GCCGGGCGAGCGCGATTCCTGACCTCATAA

Upstream 100 bases:

>100_bases
TAAATTGGCGTCTTGATTCAACGACTCGGCCGAAAGGCGTATAGAGACGCTGTGAAAGGTCGAAGGAGAGGGTCACGCGC
TGAGGCAGAAACTTTTTACC

Downstream 100 bases:

>100_bases
GCCTCAGGCCGCCTGCTTCTGCGCCTCGGTATAATAGCTAACATATTCGCCCAGATATTTTTCGGAGCTTCCGAAACCGC
CATAGCGCGACAGGGCTTTC

Product: metallophosphoesterase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLGGGKHGAARARLRIDLRDTIVYAIGDVHGCFKELERLEQKIADDASGFSGRKLIIMLGDYVDRGPDSAQVVEHLLQNP
PEGFQRICLAGNHEKSFLDYLDGVLAREAWLATGGGTTLRSYGIDLSYLANLYSASEIDQMVRSSIPPAHVEFLRALPVM
AYSRQVVFVHAGIRPGIPLRDQHERDLMFIRKEFFDHAGQLDRWVIHGHTPVKKPDLSGRRLNIDTGAYMSGRLTAVQIG
AGRARFLTS

Sequences:

>Translated_249_residues
MLGGGKHGAARARLRIDLRDTIVYAIGDVHGCFKELERLEQKIADDASGFSGRKLIIMLGDYVDRGPDSAQVVEHLLQNP
PEGFQRICLAGNHEKSFLDYLDGVLAREAWLATGGGTTLRSYGIDLSYLANLYSASEIDQMVRSSIPPAHVEFLRALPVM
AYSRQVVFVHAGIRPGIPLRDQHERDLMFIRKEFFDHAGQLDRWVIHGHTPVKKPDLSGRRLNIDTGAYMSGRLTAVQIG
AGRARFLTS
>Mature_249_residues
MLGGGKHGAARARLRIDLRDTIVYAIGDVHGCFKELERLEQKIADDASGFSGRKLIIMLGDYVDRGPDSAQVVEHLLQNP
PEGFQRICLAGNHEKSFLDYLDGVLAREAWLATGGGTTLRSYGIDLSYLANLYSASEIDQMVRSSIPPAHVEFLRALPVM
AYSRQVVFVHAGIRPGIPLRDQHERDLMFIRKEFFDHAGQLDRWVIHGHTPVKKPDLSGRRLNIDTGAYMSGRLTAVQIG
AGRARFLTS

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 27651; Mature: 27651

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGGGKHGAARARLRIDLRDTIVYAIGDVHGCFKELERLEQKIADDASGFSGRKLIIMLG
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
DYVDRGPDSAQVVEHLLQNPPEGFQRICLAGNHEKSFLDYLDGVLAREAWLATGGGTTLR
CHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCCHH
SYGIDLSYLANLYSASEIDQMVRSSIPPAHVEFLRALPVMAYSRQVVFVHAGIRPGIPLR
HHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
DQHERDLMFIRKEFFDHAGQLDRWVIHGHTPVKKPDLSGRRLNIDTGAYMSGRLTAVQIG
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEC
AGRARFLTS
CCCCCCCCC
>Mature Secondary Structure
MLGGGKHGAARARLRIDLRDTIVYAIGDVHGCFKELERLEQKIADDASGFSGRKLIIMLG
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
DYVDRGPDSAQVVEHLLQNPPEGFQRICLAGNHEKSFLDYLDGVLAREAWLATGGGTTLR
CHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCCHH
SYGIDLSYLANLYSASEIDQMVRSSIPPAHVEFLRALPVMAYSRQVVFVHAGIRPGIPLR
HHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
DQHERDLMFIRKEFFDHAGQLDRWVIHGHTPVKKPDLSGRRLNIDTGAYMSGRLTAVQIG
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEC
AGRARFLTS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA