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The map label for this gene is dppB [H]

Identifier: 110632437

GI number: 110632437

Start: 101518

End: 102468

Strand: Direct

Name: dppB [H]

Synonym: Meso_0075

Alternate gene names: 110632437

Gene position: 101518-102468 (Clockwise)

Preceding gene: 110632436

Following gene: 110632438

Centisome position: 2.3

GC content: 60.99

Gene sequence:

>951_bases
ATGTTGCACTCTGCGATCTCCCGGCTGGCGTCGGCCCTGAGCATGCTCTTTGTGGTCGCGACATTGGTCTTCGCCATCCA
AGTCGTCATCCCCGGCGACCCCGCCGAACTCTTGTTGAGCTCCGCGGGAAGTACTCCAACGCCTGAGAACATCGCGGCCC
TGCGCGTCGAAATGGGCCTCGATCGCCCCCTGTTGCAGCAATATGTCGAATTCCTCTGGGGCGCTGTTCGCCTCGATTTT
GGAAACTCGCTCATCGACAATTCGTCGATCGGCCAAACCATTGCGACCAGGCTGCCCAGAACTCTGGAACTGATCGCCGT
GGCCATGAGCATTGCCGTCGCCGTCGCAGTGCCGTTCGGCACGCATGCGGCATTGCGGGCAGGCGGACGCCTCGACACAG
CCGGCTCGGGCGTGTCGGCGCTGTTCGCGGCCGTACCGGTTTTCGTCATCGGCACGCTGCTGATCCTGTTGTTTGCCCAA
ACGCTAAAGCTGACTCCAGCCGGCGGCTACGCCGACTTTGGCTCGGCGCCGATCCAGCATCTGTCCAATTTGGTCCTGCC
CGCCATCACCGTGGCAATGAGCATTTTCCCAATCATCTTTCGTATGACGCGCTCATCGGTCCTCGACAGCCTTTCCAATG
AATGGGTGAGAACCGCCCTGGCCAAGGGCCTGCCCCGCCGCGCCGTTGTTCGCCGTCATGTCCTGCGCAATGCGCTCGGA
CCGGTCGTCACCGTCATCGGCCTGCAACTCGGGATCCTGCTTGGTTCCACAGTGCTGGTCGAGTTCGTTTTCAACTGGCC
CGGATTGAGTGGCTATCTCGTCACCGCGGTCGAACAGCGCGACTATCCCACCGTCCGTGCCATCATTCTCGTCGTGGCCG
CTATCTTCATCTTCATCAACCTGCTCATCGAACTCCTGCAGATGAAGCTCGATCCCCGGGTGCAGCTATGA

Upstream 100 bases:

>100_bases
CGGCCTTGCCCGCAATGTGGAAGGATTCCAATGCCTGCCAGGTTTCCTCGGGGTGACGAGCACCGCGATCCTGCTCGATC
AGGCCAGGTTCGTCTGACAA

Downstream 100 bases:

>100_bases
CCATAACCTCAGCATCCGCTAACCCCAGCTCGGCTTTCCGCTTCCCGTTGCCGCGCATCCATCCGCGGCTACGTCTGCCG
CTCGCTATCGTTGCCATCGT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLHSAISRLASALSMLFVVATLVFAIQVVIPGDPAELLLSSAGSTPTPENIAALRVEMGLDRPLLQQYVEFLWGAVRLDF
GNSLIDNSSIGQTIATRLPRTLELIAVAMSIAVAVAVPFGTHAALRAGGRLDTAGSGVSALFAAVPVFVIGTLLILLFAQ
TLKLTPAGGYADFGSAPIQHLSNLVLPAITVAMSIFPIIFRMTRSSVLDSLSNEWVRTALAKGLPRRAVVRRHVLRNALG
PVVTVIGLQLGILLGSTVLVEFVFNWPGLSGYLVTAVEQRDYPTVRAIILVVAAIFIFINLLIELLQMKLDPRVQL

Sequences:

>Translated_316_residues
MLHSAISRLASALSMLFVVATLVFAIQVVIPGDPAELLLSSAGSTPTPENIAALRVEMGLDRPLLQQYVEFLWGAVRLDF
GNSLIDNSSIGQTIATRLPRTLELIAVAMSIAVAVAVPFGTHAALRAGGRLDTAGSGVSALFAAVPVFVIGTLLILLFAQ
TLKLTPAGGYADFGSAPIQHLSNLVLPAITVAMSIFPIIFRMTRSSVLDSLSNEWVRTALAKGLPRRAVVRRHVLRNALG
PVVTVIGLQLGILLGSTVLVEFVFNWPGLSGYLVTAVEQRDYPTVRAIILVVAAIFIFINLLIELLQMKLDPRVQL
>Mature_316_residues
MLHSAISRLASALSMLFVVATLVFAIQVVIPGDPAELLLSSAGSTPTPENIAALRVEMGLDRPLLQQYVEFLWGAVRLDF
GNSLIDNSSIGQTIATRLPRTLELIAVAMSIAVAVAVPFGTHAALRAGGRLDTAGSGVSALFAAVPVFVIGTLLILLFAQ
TLKLTPAGGYADFGSAPIQHLSNLVLPAITVAMSIFPIIFRMTRSSVLDSLSNEWVRTALAKGLPRRAVVRRHVLRNALG
PVVTVIGLQLGILLGSTVLVEFVFNWPGLSGYLVTAVEQRDYPTVRAIILVVAAIFIFINLLIELLQMKLDPRVQL

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=36.283185840708, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1787053, Length=315, Percent_Identity=37.7777777777778, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=35.126582278481, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=30.9148264984227, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787761, Length=317, Percent_Identity=33.7539432176656, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=28.6764705882353, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788504, Length=287, Percent_Identity=28.2229965156794, Blast_Score=124, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33764; Mature: 33764

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHSAISRLASALSMLFVVATLVFAIQVVIPGDPAELLLSSAGSTPTPENIAALRVEMGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCC
DRPLLQQYVEFLWGAVRLDFGNSLIDNSSIGQTIATRLPRTLELIAVAMSIAVAVAVPFG
CCHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
THAALRAGGRLDTAGSGVSALFAAVPVFVIGTLLILLFAQTLKLTPAGGYADFGSAPIQH
CHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
LSNLVLPAITVAMSIFPIIFRMTRSSVLDSLSNEWVRTALAKGLPRRAVVRRHVLRNALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
PVVTVIGLQLGILLGSTVLVEFVFNWPGLSGYLVTAVEQRDYPTVRAIILVVAAIFIFIN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLIELLQMKLDPRVQL
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLHSAISRLASALSMLFVVATLVFAIQVVIPGDPAELLLSSAGSTPTPENIAALRVEMGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCC
DRPLLQQYVEFLWGAVRLDFGNSLIDNSSIGQTIATRLPRTLELIAVAMSIAVAVAVPFG
CCHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
THAALRAGGRLDTAGSGVSALFAAVPVFVIGTLLILLFAQTLKLTPAGGYADFGSAPIQH
CHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
LSNLVLPAITVAMSIFPIIFRMTRSSVLDSLSNEWVRTALAKGLPRRAVVRRHVLRNALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
PVVTVIGLQLGILLGSTVLVEFVFNWPGLSGYLVTAVEQRDYPTVRAIILVVAAIFIFIN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLIELLQMKLDPRVQL
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]