Click here to switch to the map view.

The map label for this gene is lhr [C]

Identifier: 110632391

GI number: 110632391

Start: 33614

End: 36133

Strand: Reverse

Name: lhr [C]

Synonym: Meso_0029

Alternate gene names: 110632391

Gene position: 36133-33614 (Counterclockwise)

Preceding gene: 110632392

Following gene: 110632390

Centisome position: 0.82

GC content: 64.52

Gene sequence:

>2520_bases
TTGGAACAGACGGATCTCATCGACGGCGACCGCGCCGCCCTCCTCCCCGCGCCTTTCCGCGAATGGTTCGCCGCGCGCGG
ATGGTCGCCGCGCCCGCATCAACTTGAGCTTCTACGCCGTACGCGTGAAGGTTGCTCGGTGCTGCTCATCGCGCCAACGG
GGGCAGGCAAAACGCTTGCAGGCTTCCTGCCCTCGCTCGCCGATCTCGCCCTAAGGCCAAAGCGCAAGCCGGGTGAAGCG
CATCGCGGCATCCACACGCTTTATATCTCACCGCTGAAGGCGCTCGCCGTCGATATCCAACGCAACCTGATGAAACCGGT
GGAGGAGATCGGCCTCGATATCCGCATCGAGACACGCACCGGCGACACGCCTGCGTACAAGCGCCAGCGCCAGAAATATG
CTCCGCCGGACATCCTGCTGACGACGCCGGAGCAACTTGCCCTGCTGATCGCGTCGGCGGATGCCGACCGCTTCTTTGCC
GGCTTGCGCTTTATCGTGCTGGATGAGCTGCACTCGCTCGTCACCTCAAAGCGCGGGCACCTTTTGTCGCTGGGCCTCGC
CAGAGTGCGGCGGCTGGCTCGCGGAACGACAGGCATCGGCCTTTCGGCCACGGTGGCGGAGCCGGACGCGCTACGCCGAT
GGCTCGTGGACCAGACTCCGCCGGGGGCCATGGCCGACATCGTCACAGTGGCGGGCGGTGCCAAGCCCGAAATCACGATC
CTCGATACGGACGAGCGCGTGCCTTGGTCCGGGCATTCGGCGCGCTATGCCATTCCCTCGATCTACCAGGCCATCAAACG
ACACAAGACGACGCTGCTCTTTGTCAATACGCGCAGCCAGGCCGAGCTTCTCTTCCGTGAGCTCTGGCATATCAACGAGG
ATAACCTGCCGATCGCGCTCCATCACGGCTCTCTGGACGTGGCACAGCGGCGTCGCGTGGAGAAGGCGATGGAGACGAAC
AGCCTGCGCGCGATCGTGGCCACCTCCACACTCGACCTCGGCATCGACTGGGGCGACGTGGACCTTGTCGTGCATGTAGG
CGCGCCAAAAGGGGCGAGCCGGCTTGCCCAGCGCATCGGGCGTTCCAACCACCGCATGGATGAGCCGAGCCAGGCGATCC
TCGTGCCCGCTAACCGCTTCGAGGTGATGGAGTGCCGGGCGGCGCTCGAGGCCAACTATCTCGGCGCGCAGGATACGCCC
CCCTTAGGCGAAGGGTCTCTCGACGTGCTGGCACAGCATGTGCTGGGCCGCGCCTGCGCCGGCCCCTTCGACGAGGACGA
ATTTTACGACGAGATTCGCAGCGCCGCACCCTATTCCACGCTCGACCGCGCCACCTTCGGCCGCGTCGTCGAATTCGTTG
CGACCGGCGGTTACGCGCTGAAAAGTTACGAACGCTATGCCCGCATCCGCAGGATGAAAGAGGGCCGCTGGCGCATCTCC
CATCCCAATGTCGCCCAGCAATATCGGCTCAATGTGGGTACGATCGTCGAGGCGCCGATGCTCAATGTAAGGCTCACGCG
CAGGCAGGGCGCGGGCGGCAGCGTACGCGGCGGCCTGCTGCTCGGCCAAGTGGAGGAATATTTCCTGGAGACGCTCGCGC
CGGGCGACACATTCACATTCTCCGGCCGCGTTGTGCGGTTCGAGGGCATTCGCGAGAACGAGGCCTTCGTCACCAACGCC
GCGGACCAGGACGCAATGGTGCCCTCCTATGCCGGCGGCAAATTTCCGCTCTCCACCTACCTGGCCGCCGAGGTGCGCGC
GATTCTGGCCGACCCCGCCCGGTGGAAGGCGCTGCCCGACCAGGTCTCAGACTGGCTTAGGATCCAGCAGGAAAACTCCG
TGCTGCCGCGCAAGGAGGATCTCCTGGTCGAGACCTTCCCGCGCGGCGATCGCTTCTACATGGTGGCCTATCCATTCGAG
GGCAGGCTTGCGCACCAGACGCTGGGCATGCTGCTCACGCGCAGGCTGGAGCGCTTCGGCGCGAGGCCGCTCGGCTTCGT
GGCGACGGACTATTCTCTTGCCATCTGGGCGCTGGAGGACATGGGATACATGATCCGCCGCGGCCACATTTCTCTCGGCC
GGCTCTTCGACGAGGACATGCTGGGGGAGGATCTCGAAAGCTGGCTCGCCGACAGCTGGCTCTTGAAGCGCACCTTCCGC
AATTGTGCAGTCATCTCCGGCCTGGTGGAGCGGAACCATCCCGGTAAGGAGAAGACGGGGCGGCAGGTCACGGTTTCCGC
CGACCTTATTTACGACGTTTTGCGCACCCATGAGCCCGATCACATCCTGCTTCAGGCCACATGGCATGATGCGGCGACAG
GCTTGCTCGACATCGGGCGCCTCGGCGAGATGCTGTCGCGCATCCGCGGCCGAATCATGCATAAGGATCTGGAGAGGATT
TCGCCGCTGGCGGTACCTGTAATGCTGGAAATCGGCAGGGAGCAGGTTCCCGGCAGCGCGCATGAATCATTGCTGGGCGA
GGCTGCGGAAAGCCTGATCAAGGAGGCCATGGGCGGATGA

Upstream 100 bases:

>100_bases
GTAGACGGAAAGGTCAGCTCTGGCCTGCCGGCCCAACGCCGTAGAAAAGGAAGATGCCCCCACTTGGCCGCCGATCTGTT
CTGCATTAGTTCTAATTGCC

Downstream 100 bases:

>100_bases
ATGTGGCACAGGGGATCGCGTGGGAGGCGGTGGGAATCGCCATCGCCGGCGAGCGCGCGGTCTGCGATCCCTCCGGCACG
CTTTATCTTCCTGCCGATCG

Product: DEAD/H associated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 839; Mature: 839

Protein sequence:

>839_residues
MEQTDLIDGDRAALLPAPFREWFAARGWSPRPHQLELLRRTREGCSVLLIAPTGAGKTLAGFLPSLADLALRPKRKPGEA
HRGIHTLYISPLKALAVDIQRNLMKPVEEIGLDIRIETRTGDTPAYKRQRQKYAPPDILLTTPEQLALLIASADADRFFA
GLRFIVLDELHSLVTSKRGHLLSLGLARVRRLARGTTGIGLSATVAEPDALRRWLVDQTPPGAMADIVTVAGGAKPEITI
LDTDERVPWSGHSARYAIPSIYQAIKRHKTTLLFVNTRSQAELLFRELWHINEDNLPIALHHGSLDVAQRRRVEKAMETN
SLRAIVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIGRSNHRMDEPSQAILVPANRFEVMECRAALEANYLGAQDTP
PLGEGSLDVLAQHVLGRACAGPFDEDEFYDEIRSAAPYSTLDRATFGRVVEFVATGGYALKSYERYARIRRMKEGRWRIS
HPNVAQQYRLNVGTIVEAPMLNVRLTRRQGAGGSVRGGLLLGQVEEYFLETLAPGDTFTFSGRVVRFEGIRENEAFVTNA
ADQDAMVPSYAGGKFPLSTYLAAEVRAILADPARWKALPDQVSDWLRIQQENSVLPRKEDLLVETFPRGDRFYMVAYPFE
GRLAHQTLGMLLTRRLERFGARPLGFVATDYSLAIWALEDMGYMIRRGHISLGRLFDEDMLGEDLESWLADSWLLKRTFR
NCAVISGLVERNHPGKEKTGRQVTVSADLIYDVLRTHEPDHILLQATWHDAATGLLDIGRLGEMLSRIRGRIMHKDLERI
SPLAVPVMLEIGREQVPGSAHESLLGEAAESLIKEAMGG

Sequences:

>Translated_839_residues
MEQTDLIDGDRAALLPAPFREWFAARGWSPRPHQLELLRRTREGCSVLLIAPTGAGKTLAGFLPSLADLALRPKRKPGEA
HRGIHTLYISPLKALAVDIQRNLMKPVEEIGLDIRIETRTGDTPAYKRQRQKYAPPDILLTTPEQLALLIASADADRFFA
GLRFIVLDELHSLVTSKRGHLLSLGLARVRRLARGTTGIGLSATVAEPDALRRWLVDQTPPGAMADIVTVAGGAKPEITI
LDTDERVPWSGHSARYAIPSIYQAIKRHKTTLLFVNTRSQAELLFRELWHINEDNLPIALHHGSLDVAQRRRVEKAMETN
SLRAIVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIGRSNHRMDEPSQAILVPANRFEVMECRAALEANYLGAQDTP
PLGEGSLDVLAQHVLGRACAGPFDEDEFYDEIRSAAPYSTLDRATFGRVVEFVATGGYALKSYERYARIRRMKEGRWRIS
HPNVAQQYRLNVGTIVEAPMLNVRLTRRQGAGGSVRGGLLLGQVEEYFLETLAPGDTFTFSGRVVRFEGIRENEAFVTNA
ADQDAMVPSYAGGKFPLSTYLAAEVRAILADPARWKALPDQVSDWLRIQQENSVLPRKEDLLVETFPRGDRFYMVAYPFE
GRLAHQTLGMLLTRRLERFGARPLGFVATDYSLAIWALEDMGYMIRRGHISLGRLFDEDMLGEDLESWLADSWLLKRTFR
NCAVISGLVERNHPGKEKTGRQVTVSADLIYDVLRTHEPDHILLQATWHDAATGLLDIGRLGEMLSRIRGRIMHKDLERI
SPLAVPVMLEIGREQVPGSAHESLLGEAAESLIKEAMGG
>Mature_839_residues
MEQTDLIDGDRAALLPAPFREWFAARGWSPRPHQLELLRRTREGCSVLLIAPTGAGKTLAGFLPSLADLALRPKRKPGEA
HRGIHTLYISPLKALAVDIQRNLMKPVEEIGLDIRIETRTGDTPAYKRQRQKYAPPDILLTTPEQLALLIASADADRFFA
GLRFIVLDELHSLVTSKRGHLLSLGLARVRRLARGTTGIGLSATVAEPDALRRWLVDQTPPGAMADIVTVAGGAKPEITI
LDTDERVPWSGHSARYAIPSIYQAIKRHKTTLLFVNTRSQAELLFRELWHINEDNLPIALHHGSLDVAQRRRVEKAMETN
SLRAIVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIGRSNHRMDEPSQAILVPANRFEVMECRAALEANYLGAQDTP
PLGEGSLDVLAQHVLGRACAGPFDEDEFYDEIRSAAPYSTLDRATFGRVVEFVATGGYALKSYERYARIRRMKEGRWRIS
HPNVAQQYRLNVGTIVEAPMLNVRLTRRQGAGGSVRGGLLLGQVEEYFLETLAPGDTFTFSGRVVRFEGIRENEAFVTNA
ADQDAMVPSYAGGKFPLSTYLAAEVRAILADPARWKALPDQVSDWLRIQQENSVLPRKEDLLVETFPRGDRFYMVAYPFE
GRLAHQTLGMLLTRRLERFGARPLGFVATDYSLAIWALEDMGYMIRRGHISLGRLFDEDMLGEDLESWLADSWLLKRTFR
NCAVISGLVERNHPGKEKTGRQVTVSADLIYDVLRTHEPDHILLQATWHDAATGLLDIGRLGEMLSRIRGRIMHKDLERI
SPLAVPVMLEIGREQVPGSAHESLLGEAAESLIKEAMGG

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569505, Length=343, Percent_Identity=27.4052478134111, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI38569503, Length=343, Percent_Identity=27.4052478134111, Blast_Score=87, Evalue=7e-17,
Organism=Escherichia coli, GI1787942, Length=879, Percent_Identity=27.6450511945392, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6320497, Length=433, Percent_Identity=24.7113163972286, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI9755332, Length=354, Percent_Identity=24.2937853107345, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 93351; Mature: 93351

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTDLIDGDRAALLPAPFREWFAARGWSPRPHQLELLRRTREGCSVLLIAPTGAGKTLA
CCCCCCCCCCCCEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHH
GFLPSLADLALRPKRKPGEAHRGIHTLYISPLKALAVDIQRNLMKPVEEIGLDIRIETRT
HHHHHHHHHHCCCCCCCCHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GDTPAYKRQRQKYAPPDILLTTPEQLALLIASADADRFFAGLRFIVLDELHSLVTSKRGH
CCCHHHHHHHHHCCCCCEEEECHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
LLSLGLARVRRLARGTTGIGLSATVAEPDALRRWLVDQTPPGAMADIVTVAGGAKPEITI
CHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEE
LDTDERVPWSGHSARYAIPSIYQAIKRHKTTLLFVNTRSQAELLFRELWHINEDNLPIAL
EECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEE
HHGSLDVAQRRRVEKAMETNSLRAIVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIG
ECCCCCHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCCEEEEEEECCCCCHHHHHHHHC
RSNHRMDEPSQAILVPANRFEVMECRAALEANYLGAQDTPPLGEGSLDVLAQHVLGRACA
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GPFDEDEFYDEIRSAAPYSTLDRATFGRVVEFVATGGYALKSYERYARIRRMKEGRWRIS
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEECC
HPNVAQQYRLNVGTIVEAPMLNVRLTRRQGAGGSVRGGLLLGQVEEYFLETLAPGDTFTF
CCCHHHHHCCCCCCEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
SGRVVRFEGIRENEAFVTNAADQDAMVPSYAGGKFPLSTYLAAEVRAILADPARWKALPD
CCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHH
QVSDWLRIQQENSVLPRKEDLLVETFPRGDRFYMVAYPFEGRLAHQTLGMLLTRRLERFG
HHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
ARPLGFVATDYSLAIWALEDMGYMIRRGHISLGRLFDEDMLGEDLESWLADSWLLKRTFR
CCCCCEEEECCEEEEEEHHHCCHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
NCAVISGLVERNHPGKEKTGRQVTVSADLIYDVLRTHEPDHILLQATWHDAATGLLDIGR
HHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHH
LGEMLSRIRGRIMHKDLERISPLAVPVMLEIGREQVPGSAHESLLGEAAESLIKEAMGG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQTDLIDGDRAALLPAPFREWFAARGWSPRPHQLELLRRTREGCSVLLIAPTGAGKTLA
CCCCCCCCCCCCEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHH
GFLPSLADLALRPKRKPGEAHRGIHTLYISPLKALAVDIQRNLMKPVEEIGLDIRIETRT
HHHHHHHHHHCCCCCCCCHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GDTPAYKRQRQKYAPPDILLTTPEQLALLIASADADRFFAGLRFIVLDELHSLVTSKRGH
CCCHHHHHHHHHCCCCCEEEECHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
LLSLGLARVRRLARGTTGIGLSATVAEPDALRRWLVDQTPPGAMADIVTVAGGAKPEITI
CHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEE
LDTDERVPWSGHSARYAIPSIYQAIKRHKTTLLFVNTRSQAELLFRELWHINEDNLPIAL
EECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEE
HHGSLDVAQRRRVEKAMETNSLRAIVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIG
ECCCCCHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCCEEEEEEECCCCCHHHHHHHHC
RSNHRMDEPSQAILVPANRFEVMECRAALEANYLGAQDTPPLGEGSLDVLAQHVLGRACA
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GPFDEDEFYDEIRSAAPYSTLDRATFGRVVEFVATGGYALKSYERYARIRRMKEGRWRIS
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEECC
HPNVAQQYRLNVGTIVEAPMLNVRLTRRQGAGGSVRGGLLLGQVEEYFLETLAPGDTFTF
CCCHHHHHCCCCCCEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
SGRVVRFEGIRENEAFVTNAADQDAMVPSYAGGKFPLSTYLAAEVRAILADPARWKALPD
CCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHH
QVSDWLRIQQENSVLPRKEDLLVETFPRGDRFYMVAYPFEGRLAHQTLGMLLTRRLERFG
HHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
ARPLGFVATDYSLAIWALEDMGYMIRRGHISLGRLFDEDMLGEDLESWLADSWLLKRTFR
CCCCCEEEECCEEEEEEHHHCCHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
NCAVISGLVERNHPGKEKTGRQVTVSADLIYDVLRTHEPDHILLQATWHDAATGLLDIGR
HHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHH
LGEMLSRIRGRIMHKDLERISPLAVPVMLEIGREQVPGSAHESLLGEAAESLIKEAMGG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]