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The map label for this gene is coaD

Identifier: 109948202

GI number: 109948202

Start: 1509719

End: 1510192

Strand: Reverse

Name: coaD

Synonym: Hac_1735

Alternate gene names: 109948202

Gene position: 1510192-1509719 (Counterclockwise)

Preceding gene: 109948203

Following gene: 109948201

Centisome position: 97.19

GC content: 39.03

Gene sequence:

>474_bases
ATGCAAAAAATAGGCATTTACCCCGGCACTTTTGATCCTGTTACTAATGGGCATATAGACATCATCCATCGCTCTAGCGA
ATTGTTTGAAAAACTCATTGTCGCTGTGGCGCACTCAAGCGCTAAAAACCCTATGTTTAGTTTAAAAGAGCGCTTAGAAA
TGATACAGCTTGCCACTAAAAGTTTTAAAAATGTAGAATGCATCGCATTTGAAGGGCTATTAGCCAACTTGGCTAAAGAG
TATCATTGTAGGGTGTTAGTCAGGGGTTTAAGGGTGGTGAGCGATTTTGAATACGAATTGCAAATGGGCTATGCGAACAA
ATCCTTAAACCACGAATTAGAAACCTTGTATTTCATGCCCACTTTACAAAATGCGTTTATTAGCTCTTCTATTGTGCGAT
CCATTATCGCTCATAAGGGCGATGCGAGCCATTTAGTGCCTAAAGAAATTTACCCTTTTATTTCAAAGGTTTAA

Upstream 100 bases:

>100_bases
AAAGCAAGACTTTAGAAGCGATGCAAGATTTTTTAGTGGGGAAGTGGTTTGATAGCTTAGGGATAGACAATGACTTATAC
CCGCGATGGGGGGTTGGCTG

Downstream 100 bases:

>100_bases
AATGTATGTGGTGTTAGAAGGCATTGATGGCGTGGGCAAAAGCACTCAAATAGAATTGTTAAAAAGCGCGTTTCAAAACG
CCCTTTTTACCAAAGAGCCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATKSFKNVECIAFEGLLANLAKE
YHCRVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPFISKV

Sequences:

>Translated_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATKSFKNVECIAFEGLLANLAKE
YHCRVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPFISKV
>Mature_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATKSFKNVECIAFEGLLANLAKE
YHCRVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPFISKV

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=49.0066225165563, Blast_Score=177, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_HELAH (Q17V95)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_665430.1
- ProteinModelPortal:   Q17V95
- SMR:   Q17V95
- STRING:   Q17V95
- GeneID:   4176135
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1735
- NMPDR:   fig|382638.8.peg.1678
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q17V95
- ProtClustDB:   PRK00168
- BioCyc:   HACI382638:HAC_1735-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17786; Mature: 17786

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATK
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SFKNVECIAFEGLLANLAKEYHCRVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIYPFISKV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATK
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SFKNVECIAFEGLLANLAKEYHCRVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIYPFISKV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA