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The map label for this gene is hrcA [H]

Identifier: 109947965

GI number: 109947965

Start: 1275858

End: 1276661

Strand: Reverse

Name: hrcA [H]

Synonym: Hac_1470

Alternate gene names: 109947965

Gene position: 1276661-1275858 (Counterclockwise)

Preceding gene: 109947968

Following gene: 109947964

Centisome position: 82.16

GC content: 37.19

Gene sequence:

>804_bases
ATGATGTTAAGAAGAATTGAAGTAGGTTCTAATTTGAATAAAAAAGAGAGTTTGTTAGATGCGTTTGTTAAAGCCTATCT
GCAGACCTTAGAACCCATTAGTTCTAAACGCTTAAAAGAGTTGGCGAACTTGAAAGTGTCTTGCGCGACGATTAGGAATT
ATTTTCAAGTCCTTTCTAAAGAGGGCATGCTCAATCAAGCCCATTCTAGTGGTGCTAGATTGCCCACTTTTAAGGCGTTT
GAAAACTATTGGCACAAGTCATTAAGCTTTGAAGTTTTAAGCGTGAATGAAAAACACCTAAAAAGCGCTAGTGAGAATTT
TGGGCTTTTTGTTTTGTTAAAAAAACCCAGTTTGGAGCGTTTAGAAAGAGTTATTGAGTGCGAAAAACGCTTTTTGATTT
TGGATTTTTTAGCGTTTTCTTGCACGATTGATTACAGCGTTAAAATGGAGAAGTTTTTGTTGGAGCTTGTGGGTAAAAGC
GTTAAAGAAGTGCGCTTGATCGCTGCTTCTGTCAATGCGTTGAGTTTGGCTAGACAATTAGAGCATTTGGAGTATTCCAA
CACGCAAATTGCACGCTTTAATCTAATGGGGTTAAAAACGCTTTTAAACAGCCCTTTGTTTTTTGACATTTTAGGGGGTA
AGATTTTAGAGCGTTTGAAAAAAGGGTTGCATTTTATAGAGCCTAATCACATGTTAGTGGCGCGTCCTATAAAATTTAAA
AACATGCAAGTGCAACTGCTTTGTGTAGGGAAATTGGAATGCGATTATGAAGGGTTTTTTCAAACCATTAAGGAGGAACG
ATGA

Upstream 100 bases:

>100_bases
TTATCACTTGTTTTAAAAAAGTGACAGATTATTAACTTTTCATGCTATAATGCGAGAGTCATTCCATTAAAAATGGCGAT
TGACGAGATATTTTTAAAAA

Downstream 100 bases:

>100_bases
AAGATGAACACAACCAAGAACACGATTTAAGCCAAAAAGAGCTAGAGTCTTGCGAAAATTCTTGCACTTGTGAAGGAAAA
AAACAAGAAGCGAGCGAAAA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MMLRRIEVGSNLNKKESLLDAFVKAYLQTLEPISSKRLKELANLKVSCATIRNYFQVLSKEGMLNQAHSSGARLPTFKAF
ENYWHKSLSFEVLSVNEKHLKSASENFGLFVLLKKPSLERLERVIECEKRFLILDFLAFSCTIDYSVKMEKFLLELVGKS
VKEVRLIAASVNALSLARQLEHLEYSNTQIARFNLMGLKTLLNSPLFFDILGGKILERLKKGLHFIEPNHMLVARPIKFK
NMQVQLLCVGKLECDYEGFFQTIKEER

Sequences:

>Translated_267_residues
MMLRRIEVGSNLNKKESLLDAFVKAYLQTLEPISSKRLKELANLKVSCATIRNYFQVLSKEGMLNQAHSSGARLPTFKAF
ENYWHKSLSFEVLSVNEKHLKSASENFGLFVLLKKPSLERLERVIECEKRFLILDFLAFSCTIDYSVKMEKFLLELVGKS
VKEVRLIAASVNALSLARQLEHLEYSNTQIARFNLMGLKTLLNSPLFFDILGGKILERLKKGLHFIEPNHMLVARPIKFK
NMQVQLLCVGKLECDYEGFFQTIKEER
>Mature_267_residues
MMLRRIEVGSNLNKKESLLDAFVKAYLQTLEPISSKRLKELANLKVSCATIRNYFQVLSKEGMLNQAHSSGARLPTFKAF
ENYWHKSLSFEVLSVNEKHLKSASENFGLFVLLKKPSLERLERVIECEKRFLILDFLAFSCTIDYSVKMEKFLLELVGKS
VKEVRLIAASVNALSLARQLEHLEYSNTQIARFNLMGLKTLLNSPLFFDILGGKILERLKKGLHFIEPNHMLVARPIKFK
NMQVQLLCVGKLECDYEGFFQTIKEER

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30755; Mature: 30755

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLRRIEVGSNLNKKESLLDAFVKAYLQTLEPISSKRLKELANLKVSCATIRNYFQVLSK
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EGMLNQAHSSGARLPTFKAFENYWHKSLSFEVLSVNEKHLKSASENFGLFVLLKKPSLER
CCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCEEEEEECCCHHH
LERVIECEKRFLILDFLAFSCTIDYSVKMEKFLLELVGKSVKEVRLIAASVNALSLARQL
HHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHLEYSNTQIARFNLMGLKTLLNSPLFFDILGGKILERLKKGLHFIEPNHMLVARPIKFK
HHHHCCCCEEEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCEECCCCEEEECCCEEC
NMQVQLLCVGKLECDYEGFFQTIKEER
CCEEEEEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MMLRRIEVGSNLNKKESLLDAFVKAYLQTLEPISSKRLKELANLKVSCATIRNYFQVLSK
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EGMLNQAHSSGARLPTFKAFENYWHKSLSFEVLSVNEKHLKSASENFGLFVLLKKPSLER
CCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCEEEEEECCCHHH
LERVIECEKRFLILDFLAFSCTIDYSVKMEKFLLELVGKSVKEVRLIAASVNALSLARQL
HHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHLEYSNTQIARFNLMGLKTLLNSPLFFDILGGKILERLKKGLHFIEPNHMLVARPIKFK
HHHHCCCCEEEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCEECCCCEEEECCCEEC
NMQVQLLCVGKLECDYEGFFQTIKEER
CCEEEEEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]