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The map label for this gene is infC [H]

Identifier: 109947951

GI number: 109947951

Start: 1261140

End: 1261751

Strand: Reverse

Name: infC [H]

Synonym: Hac_1456

Alternate gene names: 109947951

Gene position: 1261751-1261140 (Counterclockwise)

Preceding gene: 109947952

Following gene: 109947950

Centisome position: 81.2

GC content: 36.6

Gene sequence:

>612_bases
TTGAGTAGAAACGAAGTGTTGTTAAATGGAGACATTAATTTTAAAGAAGTGCGTTGCGTGGGTGATAATGGCGAAGTGTA
TGGGATCATTTCTTCTAGAGAAGCCCTAAATATCGCTCAAAATTTGGGCTTGGATTTAGTTTTGATTTCAGCGAGTGCAA
AACCCCCTGTGTGTAAGGTGATGGATTACAATAAATTCCGCTACCAAAATGAAAAGAAAATCAAGGAAGCTAAGAAAAAG
CAAAAGCAAATTGAAATCAAAGAGATCAAGCTTTCCACTCAAATCGCGCAAAATGATATTAACTATAAAGTCAAGCATGC
GAGAGAATTTATTGAAGCGAATAAACATGTCAAATTCAAAGTGGTTTTAAGGGGTAGGGAGAGCCAAAACTCAAGAGCTG
GGTTGGATGTGCTTTTTAGAGTCCAAGCCATGATGGAAGATTTGGCTAACCCTGAAAAAGAGCCAAAAACGGAAGGCCGT
TTTGTTTCTTGGATGTTTGTGCCTAAAGCTAAAGAAGCCTCTAAAAACGAAAAGAAAACTAAAGAAAATAATCCGCCTTT
TAATAATATTAACCTTATGAAAGGAGAAAATCATGCCAAAAATGAAGACTAA

Upstream 100 bases:

>100_bases
AAATCTTATCCATTAGAGACAGAGAAAAACAAGCTCAATATAAAATGCCCTTAAAGGAGTTTTTAAACATGGTTGAATCT
AAAATGCAAGAGGTTAGTTT

Downstream 100 bases:

>100_bases
TCGCGGTGCGTCCAAGCGTTTCAAAGTCAAAAAAAATTTGATCAAACGCGGTAGCGCTTTTAAAAGCCATATTTTGACTA
AAAAAAGCCCTAAGCGTAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSRNEVLLNGDINFKEVRCVGDNGEVYGIISSREALNIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKK
QKQIEIKEIKLSTQIAQNDINYKVKHAREFIEANKHVKFKVVLRGRESQNSRAGLDVLFRVQAMMEDLANPEKEPKTEGR
FVSWMFVPKAKEASKNEKKTKENNPPFNNINLMKGENHAKNED

Sequences:

>Translated_203_residues
MSRNEVLLNGDINFKEVRCVGDNGEVYGIISSREALNIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKK
QKQIEIKEIKLSTQIAQNDINYKVKHAREFIEANKHVKFKVVLRGRESQNSRAGLDVLFRVQAMMEDLANPEKEPKTEGR
FVSWMFVPKAKEASKNEKKTKENNPPFNNINLMKGENHAKNED
>Mature_202_residues
SRNEVLLNGDINFKEVRCVGDNGEVYGIISSREALNIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKKQ
KQIEIKEIKLSTQIAQNDINYKVKHAREFIEANKHVKFKVVLRGRESQNSRAGLDVLFRVQAMMEDLANPEKEPKTEGRF
VSWMFVPKAKEASKNEKKTKENNPPFNNINLMKGENHAKNED

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=43.3734939759036, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 23306; Mature: 23175

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNEVLLNGDINFKEVRCVGDNGEVYGIISSREALNIAQNLGLDLVLISASAKPPVCKV
CCCCCEEEECCCCEEEEEEECCCCCEEEEECCCHHHHHHHHCCEEEEEEECCCCCCEEEE
MDYNKFRYQNEKKIKEAKKKQKQIEIKEIKLSTQIAQNDINYKVKHAREFIEANKHVKFK
ECCCHHHCCCHHHHHHHHHHHHCCCHHEEEHHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
VVLRGRESQNSRAGLDVLFRVQAMMEDLANPEKEPKTEGRFVSWMFVPKAKEASKNEKKT
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHC
KENNPPFNNINLMKGENHAKNED
CCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
SRNEVLLNGDINFKEVRCVGDNGEVYGIISSREALNIAQNLGLDLVLISASAKPPVCKV
CCCCEEEECCCCEEEEEEECCCCCEEEEECCCHHHHHHHHCCEEEEEEECCCCCCEEEE
MDYNKFRYQNEKKIKEAKKKQKQIEIKEIKLSTQIAQNDINYKVKHAREFIEANKHVKFK
ECCCHHHCCCHHHHHHHHHHHHCCCHHEEEHHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
VVLRGRESQNSRAGLDVLFRVQAMMEDLANPEKEPKTEGRFVSWMFVPKAKEASKNEKKT
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHC
KENNPPFNNINLMKGENHAKNED
CCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]