BacMap

Definition	Helicobacter acinonychis str. Sheeba chromosome, complete genome.
Accession	NC_008229
Length	1,553,927

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 109947342

GI number: 109947342

Start: 676530

End: 677273

Strand: Reverse

Name: fabG [H]

Synonym: Hac_0781

Alternate gene names: 109947342

Gene position: 677273-676530 (Counterclockwise)

Preceding gene: 109947343

Following gene: 109947341

Centisome position: 43.58

GC content: 41.67

Gene sequence:

>744_bases
ATGCGTTTTACAGGGAAAAATGTTCTCATTACGGGAGCTTCTAAAGGCATTGGGGCCGAGATTGCAAGAACGCTCGCTTC
TATGGGGTTAAAAGTTTGGATCAACTATCGCAGTAATGCAGAAGTGGCTGACGCTTTGAAAAATGAACTTGAAGAAAAAG
GTCATAGGGTAGCTGTTATCAAATTTGATGCGGTTTCTGAAAACGATTTTGTTGAAGCGATACAAACCATTGTCCAAAGC
GATGGAGGTTTGTCTTACTTGGTGAATAATGCTGGTGTGGTGTGCGATAAATTAGCGATCAAAATGAAAACAGAAGATTT
TCACCATGTCATAGACAACAATCTCACTTCAGCTTTTATAGGTTGTAGGGAAGCTTTAAAGGTGATGAGCAAAAGCCGTT
TTGGGAGCGTGGTCAATATCGCTTCTATCATTGGTGAGAGAGGCAATATGGGGCAGACAAACTATTCAGCGAGTAAGGGG
GGGATGATTGCGATGAGCAAGTCCTTTGCTTATGAGGGAGCTTTAAGGAATATCCGTTTTAACTCTGTAACGCCCGGTTT
TATAGAAACCGACATGAACGCTAATTTGAAAGACGAACTCAAAGCGGATTATGTTAAAAATATTCCTTTAAACAGGCTAG
GGGCTACTAAGGAAGTGGCAGAAGCGGTAGCGTTTCTTTTGAGTGATCACTCTAGTTATATCACCGGAGAGACTCTCAAG
GTTAATGGCGGACTTTATATGTAG

Upstream 100 bases:

>100_bases
AATCAGCGCTAAAAAGAAGATTTTAAAGCGTCTTTATATGTTAAGGCGTTATGAATCAAGACTATAAAAGGCTTTGAGAA
AAATTTAATTAAGGACAATC

Downstream 100 bases:

>100_bases
CCCTAATATTTTTAACCATAATAGTTTGTAAGTAGCAAAAATCATGCTACCATTATGAGGTTATTCTAAAACAAAGAGGT
TAGTCAAATGGGGATTATTT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRFTGKNVLITGASKGIGAEIARTLASMGLKVWINYRSNAEVADALKNELEEKGHRVAVIKFDAVSENDFVEAIQTIVQS
DGGLSYLVNNAGVVCDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKG
GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGATKEVAEAVAFLLSDHSSYITGETLK
VNGGLYM

Sequences:

>Translated_247_residues
MRFTGKNVLITGASKGIGAEIARTLASMGLKVWINYRSNAEVADALKNELEEKGHRVAVIKFDAVSENDFVEAIQTIVQS
DGGLSYLVNNAGVVCDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKG
GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGATKEVAEAVAFLLSDHSSYITGETLK
VNGGLYM
>Mature_247_residues
MRFTGKNVLITGASKGIGAEIARTLASMGLKVWINYRSNAEVADALKNELEEKGHRVAVIKFDAVSENDFVEAIQTIVQS
DGGLSYLVNNAGVVCDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKG
GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGATKEVAEAVAFLLSDHSSYITGETLK
VNGGLYM

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=40.7563025210084, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=35.0194552529183, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=29.8804780876494, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=33.4710743801653, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4504505, Length=222, Percent_Identity=31.5315315315315, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=31.8548387096774, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=28.1746031746032, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=29.5833333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI59889578, Length=203, Percent_Identity=30.0492610837438, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=29.8076923076923, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=28.5106382978723, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=26.8774703557312, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.5140562248996, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI33667109, Length=241, Percent_Identity=28.2157676348548, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI66933014, Length=171, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=25.9067357512953, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=44.5344129554656, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=37.603305785124, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=30.4166666666667, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=31.1740890688259, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=30.327868852459, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=31.0204081632653, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=31.8367346938775, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=27.1653543307087, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=24.5059288537549, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787526, Length=241, Percent_Identity=26.9709543568465, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=38.7755102040816, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=39.0438247011952, Blast_Score=153, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17568967, Length=222, Percent_Identity=33.7837837837838, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=33.1983805668016, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=30.1526717557252, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=31.6205533596838, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=31.9838056680162, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=31.6793893129771, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.5171102661597, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=29.9595141700405, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.1317829457364, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.8973384030418, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.1187739463602, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.4090909090909, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=30.8943089430894, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=30.4511278195489, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.0076335877863, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=28.3524904214559, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.3893129770992, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=26.7441860465116, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=30.2583025830258, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=31.413612565445, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=28.8537549407115, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=26.8421052631579, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=31.4432989690722, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=26.7175572519084, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.5140562248996, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=125, Percent_Identity=32, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=278, Percent_Identity=28.4172661870504, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=257, Percent_Identity=32.295719844358, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=28.4584980237154, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=248, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=35.3413654618474, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=34, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=32.3770491803279, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.4, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=31.1023622047244, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=30.078125, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30.4, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=30.952380952381, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=26.4705882352941, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571387, Length=239, Percent_Identity=27.1966527196653, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24663911, Length=237, Percent_Identity=25.7383966244726, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641388, Length=240, Percent_Identity=26.25, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648944, Length=232, Percent_Identity=26.7241379310345, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=30.4568527918782, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=30.4568527918782, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26771; Mature: 26771

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTGKNVLITGASKGIGAEIARTLASMGLKVWINYRSNAEVADALKNELEEKGHRVAVI
CCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEE
KFDAVSENDFVEAIQTIVQSDGGLSYLVNNAGVVCDKLAIKMKTEDFHHVIDNNLTSAFI
EEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEHHEEEEECHHHHHHHHCCHHHHHH
GCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEE
NSVTPGFIETDMNANLKDELKADYVKNIPLNRLGATKEVAEAVAFLLSDHSSYITGETLK
CCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCCEECCCEEE
VNGGLYM
ECCCCCC
>Mature Secondary Structure
MRFTGKNVLITGASKGIGAEIARTLASMGLKVWINYRSNAEVADALKNELEEKGHRVAVI
CCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEE
KFDAVSENDFVEAIQTIVQSDGGLSYLVNNAGVVCDKLAIKMKTEDFHHVIDNNLTSAFI
EEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEHHEEEEECHHHHHHHHCCHHHHHH
GCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEE
NSVTPGFIETDMNANLKDELKADYVKNIPLNRLGATKEVAEAVAFLLSDHSSYITGETLK
CCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCCEECCCEEE
VNGGLYM
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA