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The map label for this gene is gapA [H]

Identifier: 109947272

GI number: 109947272

Start: 607818

End: 608816

Strand: Reverse

Name: gapA [H]

Synonym: Hac_0698

Alternate gene names: 109947272

Gene position: 608816-607818 (Counterclockwise)

Preceding gene: 109947278

Following gene: 109947257

Centisome position: 39.18

GC content: 38.44

Gene sequence:

>999_bases
ATGAAAATTTTTATCAATGGATTTGGCCGCATTGGGCGATGCGTTTTAAGAGCTATTTTAGAGCGCAACGACACAAACCA
CCCTTTAGAAGTGGTGGGTATCAACGACCCTGCTAATTGGGAAATTTTGGCTTATCTTTTAGAGCATGACAGCACGCATG
GGCTACTTAATAAAGAAGCGCGTTACTCTAATGGTAAGCTTATTATCGGCTCGCTAGAAATCCCTATTTTTAATAGTATC
AAAGACTTAAAAGGTGTGGATGTTATCATAGAGTGTTCAGGGAAGTTTTTAGAGCCTAAAATGTTAGAAAATTACCTTTT
GCTTGGGGCTAAAAAGATTCTTTTATCCGCCCCCTTTATCGGCGAATACGATGAAAAACAATACCCTACTTTAGTGTATG
GCATCAATCATTTTCTTTATCAAAACCAAGCAATTGTTTCTAACGCCTCTTGCACAACTAATGCAATCGCACCCATTTGC
GCGATTTTAGATAAAGCTTTTAGTATTAAAGAAGGCATGCTAACAACCGTTCATAGCTACACGAGCGATCAAAAACTCAT
TGATCTAGCCCACCCCTTAGACAAACGACGCTCTAGAGCGGCTGCAAGCAACATTATCCCCACAAGCACTAAAGCCGCTC
TAGCCTTGCATAAAGTTTTACCCAATCTCAAAAATAAAATGCATGGGCATAGCGTAAGAGTGCCTAGCCTTGATGTTTCC
ATGATAGATTTAAGTTTGTTTTTAGAAAAAAAAGCTCCTAAAGAGTCAATCAATGATTTATTGATTGAAGCTTCAAAAGG
GGCTTTAAAAGGCGTGTTAGAGATAGATTTGAAAAAAAGGGTTAGCTCTGATTTTATTTCTAATCCTAGTAGCGTTATTG
TCGCGCCTGATTTGACTTTCACGCTAGAGAATATGGTAAAAATCATGGGGTGGTATGATAATGAATGGGGGTATTCTAAT
CGTTTGGTGGATATGGCGCAGTTTATATGTCATTATTAA

Upstream 100 bases:

>100_bases
CCCTATGAAGGTCCAATATAATAACACAAAATGTAGTAAAATACCAAACAAAACCCCCTAAAAATTGAAATTGAAGTCTG
AAAATAGGATAATAGTTACG

Downstream 100 bases:

>100_bases
GTCATTGTTATCAATCTTTTGAGTTTGTTTGACCTAAAAGTTGTAAAAGCGCTTTTAAAAAGCTATCATTCGCTCACGCA
AGCTCTTTGATGTTTATTTA

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKIFINGFGRIGRCVLRAILERNDTNHPLEVVGINDPANWEILAYLLEHDSTHGLLNKEARYSNGKLIIGSLEIPIFNSI
KDLKGVDVIIECSGKFLEPKMLENYLLLGAKKILLSAPFIGEYDEKQYPTLVYGINHFLYQNQAIVSNASCTTNAIAPIC
AILDKAFSIKEGMLTTVHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTSTKAALALHKVLPNLKNKMHGHSVRVPSLDVS
MIDLSLFLEKKAPKESINDLLIEASKGALKGVLEIDLKKRVSSDFISNPSSVIVAPDLTFTLENMVKIMGWYDNEWGYSN
RLVDMAQFICHY

Sequences:

>Translated_332_residues
MKIFINGFGRIGRCVLRAILERNDTNHPLEVVGINDPANWEILAYLLEHDSTHGLLNKEARYSNGKLIIGSLEIPIFNSI
KDLKGVDVIIECSGKFLEPKMLENYLLLGAKKILLSAPFIGEYDEKQYPTLVYGINHFLYQNQAIVSNASCTTNAIAPIC
AILDKAFSIKEGMLTTVHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTSTKAALALHKVLPNLKNKMHGHSVRVPSLDVS
MIDLSLFLEKKAPKESINDLLIEASKGALKGVLEIDLKKRVSSDFISNPSSVIVAPDLTFTLENMVKIMGWYDNEWGYSN
RLVDMAQFICHY
>Mature_332_residues
MKIFINGFGRIGRCVLRAILERNDTNHPLEVVGINDPANWEILAYLLEHDSTHGLLNKEARYSNGKLIIGSLEIPIFNSI
KDLKGVDVIIECSGKFLEPKMLENYLLLGAKKILLSAPFIGEYDEKQYPTLVYGINHFLYQNQAIVSNASCTTNAIAPIC
AILDKAFSIKEGMLTTVHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTSTKAALALHKVLPNLKNKMHGHSVRVPSLDVS
MIDLSLFLEKKAPKESINDLLIEASKGALKGVLEIDLKKRVSSDFISNPSSVIVAPDLTFTLENMVKIMGWYDNEWGYSN
RLVDMAQFICHY

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=37.7581120943953, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=39.5209580838323, Blast_Score=230, Evalue=1e-60,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=40.1785714285714, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1789295, Length=332, Percent_Identity=38.5542168674699, Blast_Score=228, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17534677, Length=344, Percent_Identity=40.406976744186, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=344, Percent_Identity=40.1162790697674, Blast_Score=240, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=344, Percent_Identity=38.953488372093, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17568413, Length=343, Percent_Identity=38.7755102040816, Blast_Score=232, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6322409, Length=340, Percent_Identity=40, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=38.6430678466077, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321631, Length=340, Percent_Identity=38.8235294117647, Blast_Score=231, Evalue=9e-62,
Organism=Drosophila melanogaster, GI19922412, Length=335, Percent_Identity=40.2985074626866, Blast_Score=224, Evalue=5e-59,
Organism=Drosophila melanogaster, GI85725000, Length=338, Percent_Identity=38.7573964497041, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI22023983, Length=338, Percent_Identity=38.7573964497041, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17933600, Length=338, Percent_Identity=38.7573964497041, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI18110149, Length=338, Percent_Identity=38.7573964497041, Blast_Score=222, Evalue=2e-58,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37026; Mature: 37026

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFINGFGRIGRCVLRAILERNDTNHPLEVVGINDPANWEILAYLLEHDSTHGLLNKEA
CEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
RYSNGKLIIGSLEIPIFNSIKDLKGVDVIIECSGKFLEPKMLENYLLLGAKKILLSAPFI
CCCCCCEEEEEECCCHHHCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GEYDEKQYPTLVYGINHFLYQNQAIVSNASCTTNAIAPICAILDKAFSIKEGMLTTVHSY
CCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHC
TSDQKLIDLAHPLDKRRSRAAASNIIPTSTKAALALHKVLPNLKNKMHGHSVRVPSLDVS
CCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
MIDLSLFLEKKAPKESINDLLIEASKGALKGVLEIDLKKRVSSDFISNPSSVIVAPDLTF
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
TLENMVKIMGWYDNEWGYSNRLVDMAQFICHY
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKIFINGFGRIGRCVLRAILERNDTNHPLEVVGINDPANWEILAYLLEHDSTHGLLNKEA
CEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
RYSNGKLIIGSLEIPIFNSIKDLKGVDVIIECSGKFLEPKMLENYLLLGAKKILLSAPFI
CCCCCCEEEEEECCCHHHCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GEYDEKQYPTLVYGINHFLYQNQAIVSNASCTTNAIAPICAILDKAFSIKEGMLTTVHSY
CCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHC
TSDQKLIDLAHPLDKRRSRAAASNIIPTSTKAALALHKVLPNLKNKMHGHSVRVPSLDVS
CCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
MIDLSLFLEKKAPKESINDLLIEASKGALKGVLEIDLKKRVSSDFISNPSSVIVAPDLTF
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
TLENMVKIMGWYDNEWGYSNRLVDMAQFICHY
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]