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The map label for this gene is ppiD [H]

Identifier: 109947212

GI number: 109947212

Start: 555305

End: 556768

Strand: Reverse

Name: ppiD [H]

Synonym: Hac_0634

Alternate gene names: 109947212

Gene position: 556768-555305 (Counterclockwise)

Preceding gene: 109947221

Following gene: 109947211

Centisome position: 35.83

GC content: 36.07

Gene sequence:

>1464_bases
ATGATTGAATGGATGCAAAATCATAGAAAATATTTAGTGGTTACAATATGGATAAGTGCGATCGCTTTTATTGCCGCTGG
AATGATAGGTTGGGGGCAATACAGCTTTTCTTTAGATAGCAATAGTGCTGCCAAAGTGGGAAAAATTAATATTTCTCAAG
AAGAATTAGCCCAAGAATACCGCCGCCTTAAAGACGCTTATGCCGAGTCTATCCCCAATTTTAAAGAACTCACTGAAGAA
CAAATCAGAGCCATGCATTTAGAAAAAAGCGCTCTCAATATTCTCATTAATCAAGCCTTATTAAGAAATCTCGCTTTAGA
TTTAGGGCTTGGAGCCACGAAGCAAGAAATCGCTAAAGAGATTAGAAAAACAAGCGTTTTTCAAAAAGATGGCGTTTTTG
ATGAAGAGTTGTATAAAAATATCTTAAAACAAAACAATTACCGCCCCAAACTCTTTGAAGAAAGCGTTGAAAGGCTTTTA
ATCCTTCAAAAAATCAGCACTCTATTCCCCAAAACCACCACCCCTTTGGAACAATCCAGTCTGTCGCTTTGGGCGAAATT
GCAAGACAAGTTAGACATTCTTATCCTAAAACCTAGTGATGTTAAAATTTCTCTCAATGAAGAGGAAATGAAAAAGTATT
ATGAATCCCATAAAAAGGACTTTAAAAAGCCCACGAGCTTTAAAACACGATCTTTATATTTTGACGCTAATTTAGAAAAA
TCTGATTTGAAAGAATTAGAAGAATACTACAACAAAAACAAGGCGTCTTATTTGGATAAAGAGGGGAAATTACAGGATTT
TAAAAGCGTTCAAGAGCAAGTCAAGCATGATTTGAGCATGCAAAAAGCGAATGAAAAGGCTTTAAGGAGTTATATTGCTT
TAAAAAAGGGGAACACGCAAAACTACACCACGCAAGATTTTGAAGAAAACAACTCCCCCTATACCACTGAAATCACGCAA
AAACTCACCACTCTCAAACCCCTTGAAATCCTAAAACCTGAGCCTTTTAAAGATGGTTTTATTGTGGTGCAGCTTGTCTC
TCAAACTAAAGACGAATTGCAAAATTTTGATGGAGTCAAAAGCGCTCTTAAAACCCGTTTGACTCAAGAAAAAACCCTTA
TGGCGCTGCAAACTTTAGCCAAAGAAAAGCTTAAGGATTTTAAGGGAAAAAGCGTGGGCTATGTGAGTCCTAATTTTGCA
GGCACCATTAATGAGCTTAACCAAGAAGAAAGCGCTAAGTTTATCAACACCATTTTTAACCGCCAAGAAAAAAAAGGGGT
TGTTATTATAGGCGATAAAGTGGTGCTTTATCAAATCATAGAACAAAATTTCAACCACCCATTTAGCACAGAAGAAAGCC
AATATATGGATCGTCTCGTCAATAACACTAAAACGGATTTTTTTGATAAGGCTTTGATGGAAGAATTGAAAAAACGCTAT
AAGATAGTCAAATACATTCAATAA

Upstream 100 bases:

>100_bases
TTTAATAACCTTTGGTTAGAATAAGGTTATTTGATTTTACTATAAGGTTGTTTAAACTTGAATTTCATATTTTTTATTTT
TCAAAGGGATTAGAGTTCTT

Downstream 100 bases:

>100_bases
ATACAAGGGAAAATAATGGAACATAAAGAAATCGTTATAGGGGTTGATATAGGCTCTAGGAAGATTTGTGCGATAGTGGC
TGAATTTAAAGATGGGATTT

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MIEWMQNHRKYLVVTIWISAIAFIAAGMIGWGQYSFSLDSNSAAKVGKINISQEELAQEYRRLKDAYAESIPNFKELTEE
QIRAMHLEKSALNILINQALLRNLALDLGLGATKQEIAKEIRKTSVFQKDGVFDEELYKNILKQNNYRPKLFEESVERLL
ILQKISTLFPKTTTPLEQSSLSLWAKLQDKLDILILKPSDVKISLNEEEMKKYYESHKKDFKKPTSFKTRSLYFDANLEK
SDLKELEEYYNKNKASYLDKEGKLQDFKSVQEQVKHDLSMQKANEKALRSYIALKKGNTQNYTTQDFEENNSPYTTEITQ
KLTTLKPLEILKPEPFKDGFIVVQLVSQTKDELQNFDGVKSALKTRLTQEKTLMALQTLAKEKLKDFKGKSVGYVSPNFA
GTINELNQEESAKFINTIFNRQEKKGVVIIGDKVVLYQIIEQNFNHPFSTEESQYMDRLVNNTKTDFFDKALMEELKKRY
KIVKYIQ

Sequences:

>Translated_487_residues
MIEWMQNHRKYLVVTIWISAIAFIAAGMIGWGQYSFSLDSNSAAKVGKINISQEELAQEYRRLKDAYAESIPNFKELTEE
QIRAMHLEKSALNILINQALLRNLALDLGLGATKQEIAKEIRKTSVFQKDGVFDEELYKNILKQNNYRPKLFEESVERLL
ILQKISTLFPKTTTPLEQSSLSLWAKLQDKLDILILKPSDVKISLNEEEMKKYYESHKKDFKKPTSFKTRSLYFDANLEK
SDLKELEEYYNKNKASYLDKEGKLQDFKSVQEQVKHDLSMQKANEKALRSYIALKKGNTQNYTTQDFEENNSPYTTEITQ
KLTTLKPLEILKPEPFKDGFIVVQLVSQTKDELQNFDGVKSALKTRLTQEKTLMALQTLAKEKLKDFKGKSVGYVSPNFA
GTINELNQEESAKFINTIFNRQEKKGVVIIGDKVVLYQIIEQNFNHPFSTEESQYMDRLVNNTKTDFFDKALMEELKKRY
KIVKYIQ
>Mature_487_residues
MIEWMQNHRKYLVVTIWISAIAFIAAGMIGWGQYSFSLDSNSAAKVGKINISQEELAQEYRRLKDAYAESIPNFKELTEE
QIRAMHLEKSALNILINQALLRNLALDLGLGATKQEIAKEIRKTSVFQKDGVFDEELYKNILKQNNYRPKLFEESVERLL
ILQKISTLFPKTTTPLEQSSLSLWAKLQDKLDILILKPSDVKISLNEEEMKKYYESHKKDFKKPTSFKTRSLYFDANLEK
SDLKELEEYYNKNKASYLDKEGKLQDFKSVQEQVKHDLSMQKANEKALRSYIALKKGNTQNYTTQDFEENNSPYTTEITQ
KLTTLKPLEILKPEPFKDGFIVVQLVSQTKDELQNFDGVKSALKTRLTQEKTLMALQTLAKEKLKDFKGKSVGYVSPNFA
GTINELNQEESAKFINTIFNRQEKKGVVIIGDKVVLYQIIEQNFNHPFSTEESQYMDRLVNNTKTDFFDKALMEELKKRY
KIVKYIQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=269, Percent_Identity=24.1635687732342, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 56549; Mature: 56549

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEWMQNHRKYLVVTIWISAIAFIAAGMIGWGQYSFSLDSNSAAKVGKINISQEELAQEY
CCCCHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCHHHHHHHH
RRLKDAYAESIPNFKELTEEQIRAMHLEKSALNILINQALLRNLALDLGLGATKQEIAKE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IRKTSVFQKDGVFDEELYKNILKQNNYRPKLFEESVERLLILQKISTLFPKTTTPLEQSS
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LSLWAKLQDKLDILILKPSDVKISLNEEEMKKYYESHKKDFKKPTSFKTRSLYFDANLEK
HHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCH
SDLKELEEYYNKNKASYLDKEGKLQDFKSVQEQVKHDLSMQKANEKALRSYIALKKGNTQ
HHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NYTTQDFEENNSPYTTEITQKLTTLKPLEILKPEPFKDGFIVVQLVSQTKDELQNFDGVK
CCCCCCHHCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
SALKTRLTQEKTLMALQTLAKEKLKDFKGKSVGYVSPNFAGTINELNQEESAKFINTIFN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHC
RQEKKGVVIIGDKVVLYQIIEQNFNHPFSTEESQYMDRLVNNTKTDFFDKALMEELKKRY
CHHCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KIVKYIQ
HHHHHCC
>Mature Secondary Structure
MIEWMQNHRKYLVVTIWISAIAFIAAGMIGWGQYSFSLDSNSAAKVGKINISQEELAQEY
CCCCHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCHHHHHHHH
RRLKDAYAESIPNFKELTEEQIRAMHLEKSALNILINQALLRNLALDLGLGATKQEIAKE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IRKTSVFQKDGVFDEELYKNILKQNNYRPKLFEESVERLLILQKISTLFPKTTTPLEQSS
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LSLWAKLQDKLDILILKPSDVKISLNEEEMKKYYESHKKDFKKPTSFKTRSLYFDANLEK
HHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCH
SDLKELEEYYNKNKASYLDKEGKLQDFKSVQEQVKHDLSMQKANEKALRSYIALKKGNTQ
HHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NYTTQDFEENNSPYTTEITQKLTTLKPLEILKPEPFKDGFIVVQLVSQTKDELQNFDGVK
CCCCCCHHCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
SALKTRLTQEKTLMALQTLAKEKLKDFKGKSVGYVSPNFAGTINELNQEESAKFINTIFN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHC
RQEKKGVVIIGDKVVLYQIIEQNFNHPFSTEESQYMDRLVNNTKTDFFDKALMEELKKRY
CHHCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KIVKYIQ
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]