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The map label for this gene is galE [H]

Identifier: 109947021

GI number: 109947021

Start: 361236

End: 362270

Strand: Reverse

Name: galE [H]

Synonym: Hac_0415

Alternate gene names: 109947021

Gene position: 362270-361236 (Counterclockwise)

Preceding gene: 109947022

Following gene: 109947016

Centisome position: 23.31

GC content: 39.13

Gene sequence:

>1035_bases
ATGGCATTACTATTCACAGGGGCATGCGGATACATAGGCTCGCATACCGCAAGGGCGTTTTTAGAAAATACCACAGAAAA
CATCATTATTGTAGATGATTTAAGCACCGGTTTTTTAGAGCATATCAAAGCATTGGAGCATTACTACCTTAATAGAGTCA
TGTTTATTCAAGCGAATTTGAATGAGACGCAAAAATTAGACGCATTTTTGAATAAGCAACAATTACAAGATCCTATTGAG
ACTATCTTACACTTTGGGGCTAAAATCTCCGTAGAAGAATCAATGCACTTGCCTTTAGAATACTACACCAACAACACGCT
TAACACTTTAGAGCTTGTCAAACTTTGCTTGAAACACCACATCAAGCGTTTTATTTTTTCTTCCACAGCCGTGGTTTATG
GCGAGTCCAATTCAAGCTTGAACGAAGAAAGCCCCTTAAACCCCATCAATCCTTATGGAGCGTCTAAAATGATGAGTGAG
AGAATTTTATTAGACGCTTCTAAAGTGGCGGATTTTAACTGCGTTATTTTGCGCTATTTCAATGTGGCTGGGGCATGCAT
GCAAAATGATTATACTACGCCCTACACTTTGGGTCAGCGCACCCTAAACGCCACACATTTAATCAAAATTGCATGCGAAT
GCGCGGTGGGGAAAAGGAAAAAAATGGGGATTTTTGGCACCGATTACCCCACAAGAGATGGCACATGCATTAGGGATTAT
ATCCATGTAGATGATTTGGCTAATGCACATTTAGCGAGCTATCGGGCTCTTTTAGAACAAAATAAGAGCGAAATTTATAA
TGTCGGCTACAATCAAGGGCATAGCGTGAAAGAAGTGATTAATAAGGTTAAAGAAATCTCAAACAACGATTTTTTAGTAG
AGATTTTAGACAAACGACAAGGCGATCCAGCAAGCCTTATTGCCAATAACGCTAAAATCTTACAAAACACCTCTTTCAAA
CCCCTTTATAACAACCTAGACACCATCATCAAAAGCGCTTTGGCTTGGGAAGAACACCTTTTAAGATTTCAATAA

Upstream 100 bases:

>100_bases
TTGTAGATTAAACTTCCTTAAAAAATCCTTAAAAAATAAATGAGATTATGATGCTATAATACTTGAATACTTGTTATTTT
TTCATTATTAAAGGGGTTTT

Downstream 100 bases:

>100_bases
TGCACCCTATGTAAATACAATCCGTTAGCCATTATGGGCGTTCTTATGGTGGCTTTGATGTTATTGATTTGTGTTTTAAT
TTCAGCGAGCGTGATTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MALLFTGACGYIGSHTARAFLENTTENIIIVDDLSTGFLEHIKALEHYYLNRVMFIQANLNETQKLDAFLNKQQLQDPIE
TILHFGAKISVEESMHLPLEYYTNNTLNTLELVKLCLKHHIKRFIFSSTAVVYGESNSSLNEESPLNPINPYGASKMMSE
RILLDASKVADFNCVILRYFNVAGACMQNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTDYPTRDGTCIRDY
IHVDDLANAHLASYRALLEQNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTSFK
PLYNNLDTIIKSALAWEEHLLRFQ

Sequences:

>Translated_344_residues
MALLFTGACGYIGSHTARAFLENTTENIIIVDDLSTGFLEHIKALEHYYLNRVMFIQANLNETQKLDAFLNKQQLQDPIE
TILHFGAKISVEESMHLPLEYYTNNTLNTLELVKLCLKHHIKRFIFSSTAVVYGESNSSLNEESPLNPINPYGASKMMSE
RILLDASKVADFNCVILRYFNVAGACMQNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTDYPTRDGTCIRDY
IHVDDLANAHLASYRALLEQNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTSFK
PLYNNLDTIIKSALAWEEHLLRFQ
>Mature_343_residues
ALLFTGACGYIGSHTARAFLENTTENIIIVDDLSTGFLEHIKALEHYYLNRVMFIQANLNETQKLDAFLNKQQLQDPIET
ILHFGAKISVEESMHLPLEYYTNNTLNTLELVKLCLKHHIKRFIFSSTAVVYGESNSSLNEESPLNPINPYGASKMMSER
ILLDASKVADFNCVILRYFNVAGACMQNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTDYPTRDGTCIRDYI
HVDDLANAHLASYRALLEQNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTSFKP
LYNNLDTIIKSALAWEEHLLRFQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=349, Percent_Identity=32.0916905444126, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI56118217, Length=349, Percent_Identity=32.0916905444126, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI189083684, Length=349, Percent_Identity=32.0916905444126, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI7657641, Length=305, Percent_Identity=26.8852459016393, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=33.7243401759531, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1788353, Length=321, Percent_Identity=25.5451713395639, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790049, Length=280, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=318, Percent_Identity=35.5345911949685, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI71982038, Length=320, Percent_Identity=35.3125, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17568069, Length=277, Percent_Identity=27.4368231046931, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=318, Percent_Identity=35.5345911949685, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=29.512893982808, Blast_Score=156, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38924; Mature: 38793

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLFTGACGYIGSHTARAFLENTTENIIIVDDLSTGFLEHIKALEHYYLNRVMFIQANL
CEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCEEEEEEECC
NETQKLDAFLNKQQLQDPIETILHFGAKISVEESMHLPLEYYTNNTLNTLELVKLCLKHH
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEECCCCCCHHHHHHHHHHHH
IKRFIFSSTAVVYGESNSSLNEESPLNPINPYGASKMMSERILLDASKVADFNCVILRYF
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
NVAGACMQNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTDYPTRDGTCIRDY
HHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
IHVDDLANAHLASYRALLEQNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQ
HHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCC
GDPASLIANNAKILQNTSFKPLYNNLDTIIKSALAWEEHLLRFQ
CCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALLFTGACGYIGSHTARAFLENTTENIIIVDDLSTGFLEHIKALEHYYLNRVMFIQANL
EEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCEEEEEEECC
NETQKLDAFLNKQQLQDPIETILHFGAKISVEESMHLPLEYYTNNTLNTLELVKLCLKHH
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEECCCCCCHHHHHHHHHHHH
IKRFIFSSTAVVYGESNSSLNEESPLNPINPYGASKMMSERILLDASKVADFNCVILRYF
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
NVAGACMQNDYTTPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTDYPTRDGTCIRDY
HHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
IHVDDLANAHLASYRALLEQNKSEIYNVGYNQGHSVKEVINKVKEISNNDFLVEILDKRQ
HHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCC
GDPASLIANNAKILQNTSFKPLYNNLDTIIKSALAWEEHLLRFQ
CCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]