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The map label for this gene is 109946972

Identifier: 109946972

GI number: 109946972

Start: 309299

End: 310321

Strand: Reverse

Name: 109946972

Synonym: Hac_0364

Alternate gene names: NA

Gene position: 310321-309299 (Counterclockwise)

Preceding gene: 109946973

Following gene: 109946964

Centisome position: 19.97

GC content: 37.73

Gene sequence:

>1023_bases
ATGTTACAATACCCTAAAATTGTCGCTGAATTGAGCGCTAATCATAACCAAGATTTAAATCTCGCTAAAGAAAGCCTTCA
TGCCATTAAGGAGAGTGGTGCGGATTTTGTGAAGCTCCAAACCTACACCCCAAGTTGCATGACTTTAAACTCCAAAGAAG
ATCCTTTCATCATTCAAGGCACTTTGTGGGATAAAGAAAATTTGTATGCGTTGTATCAAAAGGCTTCTACCCCCCTAGAA
TGGCATGCTGAATTGTTTGAGTTAGCTAAAAAGCTTGATTTAGGTATTTTTAGCTCGCCCTTTAGCTCACAAGCTTTAGA
GCTTTTAGAGAGTTTGGATTGCCCTATGTATAAAATCGCTAGTTTTGAAATCGTTGATTTAGATTTGATTGAAAAGGTTG
CACACACAAAAAAGCCCATTATCCTTTCTAGCGGTATCGCTACACACACTGAATTGCAAGACGCTATAAATTTGTGCAAA
GAAGTGAATAATTTTGACATCACCCTTTTAAAATGCGTGAGCGCTTATCCTAGCCAATTAGAAGACGCTAATTTGTTGAG
CATGGTTAAATTGGGCGAAAAGTTTGGCGTCAAATTTGGCTTGAGCGATCATACGATTGGCTCTCTTTGTCCCATTTTAG
CTACCACTTTGGGAGCGAGCATGATAGAAAAGCATTTCATTTTAAACAAATCCTTACAAACCCTAGACAGCGCTTTTAGC
ATGGATTTTAACGAATTTAAAAACATGGTCAAAACAATCAAACAAAGTGTTTTAGCTTTAGGCGAAGAAGAGCCCAAAAT
CAATCCAAAGACTTTAGAGAAGCAAAGATTTTTCGCCCGCTCTTTATTTGTTATTAAGGATATTCAAAAAGGCGAAACAT
TGACTAGCGATAATATCAAAGCCTTACGCCCCAATCTTGGTCTACACCCTAAATTTTATAAAGAAATTTTAGGTCAAAGA
GCATCAAAATTCTTGAAAGCCAACACCCCTTTAAACGCTGATGGCATAAAACGATCGCTGTAG

Upstream 100 bases:

>100_bases
AAGGGGCGTTAGTTTTAGCCACGCATGATGAACATTTAGCTTTCACTTGCTCTCAAGTCTATCGCTTAGAAAAAGAAGTT
TTGATTAAGGAAAAATAAAA

Downstream 100 bases:

>100_bases
GTTTGTTTTGATGAAAAAGTGGGGTTTTAAAACTTTGTTTTTATCGTTTTAGATTTATTTTATTTTTGATTAAAATTTTT
AAAAATTATATTTTATTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLQYPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYALYQKASTPLE
WHAELFELAKKLDLGIFSSPFSSQALELLESLDCPMYKIASFEIVDLDLIEKVAHTKKPIILSSGIATHTELQDAINLCK
EVNNFDITLLKCVSAYPSQLEDANLLSMVKLGEKFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTLDSAFS
MDFNEFKNMVKTIKQSVLALGEEEPKINPKTLEKQRFFARSLFVIKDIQKGETLTSDNIKALRPNLGLHPKFYKEILGQR
ASKFLKANTPLNADGIKRSL

Sequences:

>Translated_340_residues
MLQYPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYALYQKASTPLE
WHAELFELAKKLDLGIFSSPFSSQALELLESLDCPMYKIASFEIVDLDLIEKVAHTKKPIILSSGIATHTELQDAINLCK
EVNNFDITLLKCVSAYPSQLEDANLLSMVKLGEKFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTLDSAFS
MDFNEFKNMVKTIKQSVLALGEEEPKINPKTLEKQRFFARSLFVIKDIQKGETLTSDNIKALRPNLGLHPKFYKEILGQR
ASKFLKANTPLNADGIKRSL
>Mature_340_residues
MLQYPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYALYQKASTPLE
WHAELFELAKKLDLGIFSSPFSSQALELLESLDCPMYKIASFEIVDLDLIEKVAHTKKPIILSSGIATHTELQDAINLCK
EVNNFDITLLKCVSAYPSQLEDANLLSMVKLGEKFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTLDSAFS
MDFNEFKNMVKTIKQSVLALGEEEPKINPKTLEKQRFFARSLFVIKDIQKGETLTSDNIKALRPNLGLHPKFYKEILGQR
ASKFLKANTPLNADGIKRSL

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=330, Percent_Identity=28.7878787878788, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357081, Length=252, Percent_Identity=28.1746031746032, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38058; Mature: 38058

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQYPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYALYQKASTPLEWHAELFELAKKLDLGIFSSPFSSQALELLESLDCPMYKIA
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEECC
SFEIVDLDLIEKVAHTKKPIILSSGIATHTELQDAINLCKEVNNFDITLLKCVSAYPSQL
CEEEECHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
EDANLLSMVKLGEKFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTLDSAFS
CCHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDFNEFKNMVKTIKQSVLALGEEEPKINPKTLEKQRFFARSLFVIKDIQKGETLTSDNIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILGQRASKFLKANTPLNADGIKRSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLQYPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYALYQKASTPLEWHAELFELAKKLDLGIFSSPFSSQALELLESLDCPMYKIA
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEECC
SFEIVDLDLIEKVAHTKKPIILSSGIATHTELQDAINLCKEVNNFDITLLKCVSAYPSQL
CEEEECHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
EDANLLSMVKLGEKFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTLDSAFS
CCHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDFNEFKNMVKTIKQSVLALGEEEPKINPKTLEKQRFFARSLFVIKDIQKGETLTSDNIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILGQRASKFLKANTPLNADGIKRSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]