Click here to switch to the map view.

The map label for this gene is aroK

Identifier: 109946950

GI number: 109946950

Start: 287833

End: 288321

Strand: Direct

Name: aroK

Synonym: Hac_0340

Alternate gene names: 109946950

Gene position: 287833-288321 (Clockwise)

Preceding gene: 109946949

Following gene: 109946951

Centisome position: 18.52

GC content: 37.01

Gene sequence:

>489_bases
ATGCAGCATTTAGTCTTAATTGGTTTTATGGGGAGCGGTAAAAGCTCTTTAGCACAAGAATTGGGGTTGGCTTTGAATTT
GGAAGTGTTGGATACAGACATGATCATTAGCGAAAGGGTAGGCTTGAGCGTGAGGGGGATTTTTGAAGAGCTTGGCGAAG
ATAATTTCAGGATGTTTGAAAAAAACTTGATTGATGAATTAAAGATGCTAAAAAACCCCCATGTTATCTCTACGGGTGGG
GGCATTATTATGCATGATAATTTTAAGGGTTTGGGCACGACCTTTTATTTAAAAATGGATTTTGAAACGATTATCAAGCG
TTTGAGTAAAAAAGAAAGGGAAAAGCGCCCCCTTTTAAATAATTTAACTCAAGCCAAAGAGCTTTTTGAAAAACGGCAAG
CTCTCTATGAAAAAAACGCTTCTTTTATCATCAATGCACAAGGCGGTTTGAAAAAATCTTTAAAACAAGCGCTACAATTC
ATCGCATAA

Upstream 100 bases:

>100_bases
CACAAAGATTATTACCGCATCACGCTCGTTTTAGATGGGAAATACCGCTATCTTTTGGAAGAAAAAAATGGGGCTTATGA
ATTAAAATTGAAATAAAAGC

Downstream 100 bases:

>100_bases
ATTTTTTTAAAGGCCTTTTGATGTTGAGTAGAGACATTGTCCAGTATTCCAAGATCCGCACTGAATTATACGCCTATCTT
ACTTATTTGTTTTCGCACAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MQHLVLIGFMGSGKSSLAQELGLALNLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKMLKNPHVISTGG
GIIMHDNFKGLGTTFYLKMDFETIIKRLSKKEREKRPLLNNLTQAKELFEKRQALYEKNASFIINAQGGLKKSLKQALQF
IA

Sequences:

>Translated_162_residues
MQHLVLIGFMGSGKSSLAQELGLALNLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKMLKNPHVISTGG
GIIMHDNFKGLGTTFYLKMDFETIIKRLSKKEREKRPLLNNLTQAKELFEKRQALYEKNASFIINAQGGLKKSLKQALQF
IA
>Mature_162_residues
MQHLVLIGFMGSGKSSLAQELGLALNLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKMLKNPHVISTGG
GIIMHDNFKGLGTTFYLKMDFETIIKRLSKKEREKRPLLNNLTQAKELFEKRQALYEKNASFIINAQGGLKKSLKQALQF
IA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=152, Percent_Identity=35.5263157894737, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_HELAH (Q17YU7)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664178.1
- ProteinModelPortal:   Q17YU7
- SMR:   Q17YU7
- STRING:   Q17YU7
- GeneID:   4176937
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0340
- NMPDR:   fig|382638.8.peg.329
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   MIISERV
- ProtClustDB:   PRK00131
- BioCyc:   HACI382638:HAC_0340-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 18347; Mature: 18347

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 33-33 BINDING 57-57 BINDING 80-80 BINDING 116-116 BINDING 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLVLIGFMGSGKSSLAQELGLALNLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFE
CCCEEEEEECCCCHHHHHHHHCCEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
KNLIDELKMLKNPHVISTGGGIIMHDNFKGLGTTFYLKMDFETIIKRLSKKEREKRPLLN
HHHHHHHHHHCCCCEEECCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHCHHHH
NLTQAKELFEKRQALYEKNASFIINAQGGLKKSLKQALQFIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQHLVLIGFMGSGKSSLAQELGLALNLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFE
CCCEEEEEECCCCHHHHHHHHCCEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
KNLIDELKMLKNPHVISTGGGIIMHDNFKGLGTTFYLKMDFETIIKRLSKKEREKRPLLN
HHHHHHHHHHCCCCEEECCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHCHHHH
NLTQAKELFEKRQALYEKNASFIINAQGGLKKSLKQALQFIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA