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The map label for this gene is hpyIM [H]

Identifier: 109946919

GI number: 109946919

Start: 259584

End: 260573

Strand: Direct

Name: hpyIM [H]

Synonym: Hac_0306

Alternate gene names: 109946919

Gene position: 259584-260573 (Clockwise)

Preceding gene: 109946918

Following gene: 109946921

Centisome position: 16.71

GC content: 36.77

Gene sequence:

>990_bases
ATGAACTACATCGGTTCTAAATACAAGCTCATTCCCTTTATTAAGGAAAATATCCATGCGGTTGTGGGCAGTGATCTCTC
TTGCACGATTTTTTGTGATCTGTTCGCTGGGACGGGTATTGTGGGGCACGCGTTTAAAAAAGCCGTTAATAAGATTATCT
CTAATGATTTGGAGTATTATAGCTTTGTTTTGAATCAAAATTATATTGCCAACATTCAAGAGATCCCTAACAAACAAGAG
CTTATTGATGAGATTAATAGCGTTGCTTTAAAAAAGGGCTTTATCTATTCGCATTATTCTTTAGGAGGGAGTTCAAGGCA
GTATTTTAGCGAAACGAACGCTCAAAAAATTGATGCGATGCGTTTAAAAATTGAAGAGCTCAAGCGTTCTCAAAATATTG
ATGGCCATGCGTATTATTTTTTGCTCGCATCGTTATTGGAGAGTGCAGACAAGGTGGCTAATACCGCTTCAGTTTATGGG
GCTTTTTTAAAACACCTTAAAAAAAGCGCTCAAAAAGAACTCATTTTAGAAGGCGCTCATTTTGATTTGAGCCAAAACGC
TAACGAAGTATATCAGCAGGATTCCAATGATTTGATTGAAAAGATTTCAGGGGATATTTTGTATTTAGACCCCCCTTATA
ATGCGAGACAATATGGGGCGAACTATCATTTATTAAACACGATTGCCACTTATACACCCTTTATCCCAAAAGGTAAAACC
GGCTTGCCCAGTTACCAGAAATCATCGTTTTGCTCTCGCAATAAGATTTTAAATGCCTTTGAAAACTTGATCAAAAAAGC
GCGATTCAAATACATCTTTTTAAGCTATAACAATGAAGGGCTTATGAATGAAACAGAGATTAGAAATATCTTAAAAAAAT
ACGGCGCTTACTCTTTATTCACCAAAACCTACATGCGTTTTAAAGCAGACAATACACGCGTCCACAAAGCCACGCACACC
AAAGAATTTTTGCATGTTCTTATTAAGTGA

Upstream 100 bases:

>100_bases
AAACTTGTAATGATAGGATATACAATGAAGGGTATCAAAAAGGTTATGATGAGGGGTATCAAATTGGATACCATCAAAAA
ACTACTTTATAGTGGTTGCA

Downstream 100 bases:

>100_bases
GGATGAATGCGAGCGGATTTTTTATATCCATTTTAATCAGACTTGATGCAAGTTTTTCTTATATCTAATTCCGCATTTTT
TAAGTTAAAAGTTTTAGTTG

Product: adenine-specific methyltransferase

Products: NA

Alternate protein names: M.NlaIII; Adenine-specific methyltransferase NlaIII [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNYIGSKYKLIPFIKENIHAVVGSDLSCTIFCDLFAGTGIVGHAFKKAVNKIISNDLEYYSFVLNQNYIANIQEIPNKQE
LIDEINSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDAMRLKIEELKRSQNIDGHAYYFLLASLLESADKVANTASVYG
AFLKHLKKSAQKELILEGAHFDLSQNANEVYQQDSNDLIEKISGDILYLDPPYNARQYGANYHLLNTIATYTPFIPKGKT
GLPSYQKSSFCSRNKILNAFENLIKKARFKYIFLSYNNEGLMNETEIRNILKKYGAYSLFTKTYMRFKADNTRVHKATHT
KEFLHVLIK

Sequences:

>Translated_329_residues
MNYIGSKYKLIPFIKENIHAVVGSDLSCTIFCDLFAGTGIVGHAFKKAVNKIISNDLEYYSFVLNQNYIANIQEIPNKQE
LIDEINSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDAMRLKIEELKRSQNIDGHAYYFLLASLLESADKVANTASVYG
AFLKHLKKSAQKELILEGAHFDLSQNANEVYQQDSNDLIEKISGDILYLDPPYNARQYGANYHLLNTIATYTPFIPKGKT
GLPSYQKSSFCSRNKILNAFENLIKKARFKYIFLSYNNEGLMNETEIRNILKKYGAYSLFTKTYMRFKADNTRVHKATHT
KEFLHVLIK
>Mature_329_residues
MNYIGSKYKLIPFIKENIHAVVGSDLSCTIFCDLFAGTGIVGHAFKKAVNKIISNDLEYYSFVLNQNYIANIQEIPNKQE
LIDEINSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDAMRLKIEELKRSQNIDGHAYYFLLASLLESADKVANTASVYG
AFLKHLKKSAQKELILEGAHFDLSQNANEVYQQDSNDLIEKISGDILYLDPPYNARQYGANYHLLNTIATYTPFIPKGKT
GLPSYQKSSFCSRNKILNAFENLIKKARFKYIFLSYNNEGLMNETEIRNILKKYGAYSLFTKTYMRFKADNTRVHKATHT
KEFLHVLIK

Specific function: This methylase recognizes the double-stranded sequence CATG, causes specific methylation on A-2 on both strands and protects the DNA from cleavage by the NlaIII endonuclease [H]

COG id: COG3392

COG function: function code L; Adenine-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 37583; Mature: 37583

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIGSKYKLIPFIKENIHAVVGSDLSCTIFCDLFAGTGIVGHAFKKAVNKIISNDLEYY
CCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCHHHH
SFVLNQNYIANIQEIPNKQELIDEINSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDAM
HHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHCCHHHHHHH
RLKIEELKRSQNIDGHAYYFLLASLLESADKVANTASVYGAFLKHLKKSAQKELILEGAH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDLSQNANEVYQQDSNDLIEKISGDILYLDPPYNARQYGANYHLLNTIATYTPFIPKGKT
CCCCCCHHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHCCCHHHHHHHHHHCCCCCCCCC
GLPSYQKSSFCSRNKILNAFENLIKKARFKYIFLSYNNEGLMNETEIRNILKKYGAYSLF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHH
TKTYMRFKADNTRVHKATHTKEFLHVLIK
HHHHHHHCCCCCEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYIGSKYKLIPFIKENIHAVVGSDLSCTIFCDLFAGTGIVGHAFKKAVNKIISNDLEYY
CCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCHHHH
SFVLNQNYIANIQEIPNKQELIDEINSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDAM
HHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHCCHHHHHHH
RLKIEELKRSQNIDGHAYYFLLASLLESADKVANTASVYGAFLKHLKKSAQKELILEGAH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDLSQNANEVYQQDSNDLIEKISGDILYLDPPYNARQYGANYHLLNTIATYTPFIPKGKT
CCCCCCHHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHCCCHHHHHHHHHHCCCCCCCCC
GLPSYQKSSFCSRNKILNAFENLIKKARFKYIFLSYNNEGLMNETEIRNILKKYGAYSLF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHH
TKTYMRFKADNTRVHKATHTKEFLHVLIK
HHHHHHHCCCCCEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2277628 [H]