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The map label for this gene is fbcB [H]

Identifier: 109946915

GI number: 109946915

Start: 255911

End: 257149

Strand: Direct

Name: fbcB [H]

Synonym: Hac_0301

Alternate gene names: 109946915

Gene position: 255911-257149 (Clockwise)

Preceding gene: 109946914

Following gene: 109946916

Centisome position: 16.47

GC content: 40.76

Gene sequence:

>1239_bases
ATGGCAGAGATAAAAAAAGCGAAAAATTTAGGCGAATGGTTGGACATGCGTCTTGGCACTAACAAGCTTGTTAAAGTGCT
AATGACAGAATATTGGATCCCTAAAAACATCAATTTCTTATGGGCTATGGGGGTGATTTTATTAACCCTTTTTGGCGTGC
TTGTAGTTTCAGGGATTTTCTTGCTCATGTATTACAAGCCTGATGCGAAAATGGCGTTTGATAGCGTGAATTTCACAATC
ATGCAAGAAGTGGCTTATGGCTGGCTTTGGCGCCACATGCATGCCACTGCAGCAAGCATGATTTTTGTCATCATTTATAT
CCATATGTTTGTCGCTATCTATTATGGCTCTTACAAAAAGGGTCGTGAGATGATTTGGATTAGTGGCATGATTTTATTTG
TGGTCTTTAGTGCGGAAGCCTTTAGTGGGTATATGTTGCCTTGGGGGCAGATGAGCTATTGGGCGGCAGCGGTTATCACC
AATTTATTTGGAGGTATTCCTTTTATTGGGGCTGATGTGGTGGAGTGGATCAGGGGTAATTATGTCGTGGCAGATTCCAC
TTTAACGCGCTTTTTCATGCTTCATGTGTTTTTATTGCCTATTGCGATTATTTTGCTCATTGGGGTGCATTTCTACTCTT
TACGCATTCCGCATGTCAATAACCAAGAAGGCGAAGAAATTGACTTTGAATTGGAAGAGAAAAAATTCATTGAAGGCAAG
AAAAAGGAATCTAAAGTCATTCCTTTTTGGCCGGTATTCTTGTCTAAAGATATTTTTGTGGTTTGTGCATTCATGGTCTT
TTTCTTTTACTTGGTGTGTTACCACTATGATTTTGCGATGGATCCTATTAACTTTGAAAGGGCTAACAGCCTTAAAACGC
CGCCTCATATTTACCCTGAGTGGTATTTCTTATGGAGCTATGAAGTCTTAAGGGGCTTTTTCTTTAGCGCTGATTTAGGG
TTAATGGCCTTTGGCGTGGCGCAAGTGATTTTCTTCTTACTGCCTTTCTTGGATCGAAGTCCGGTGGTCGCTCCTGCACA
CAAACGGCCTGCTTTTATGGTGTGGTTTTGGCTTGTAATTATTGATATGATTGTTTTAACGATCTATGGTAAATTGCCTC
CACTTGGAATAGGTAAATACATTGGGTTGGCTGGTTCGATCACTTTCTTAGCCCTTTTCTTTGTGGTATTGCCCATTATT
ACTATTGCTGAGAGGAAGAAACAAGGGGGTGTTAGATGA

Upstream 100 bases:

>100_bases
TTGATATTCCGCCTTTTAAAGTTGAAGGCACTAAGATCACTTTTGGCGAAGCTGGGGCTGAATACAAAAACATGGTGGCT
AAAGCGTAAGGAGAGTTTCA

Downstream 100 bases:

>100_bases
AAGAATTTAAAATTCTAATTATCCTTATTGTAGTGATAGGCGTGATTTATTATGGGGTTGAGCCTTATGCACATTCTGTG
ATGCACCCTAAAGTCGCTCC

Product: ubiquinol cytochrome c oxidoreductase,cytochrome b subunit

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAEIKKAKNLGEWLDMRLGTNKLVKVLMTEYWIPKNINFLWAMGVILLTLFGVLVVSGIFLLMYYKPDAKMAFDSVNFTI
MQEVAYGWLWRHMHATAASMIFVIIYIHMFVAIYYGSYKKGREMIWISGMILFVVFSAEAFSGYMLPWGQMSYWAAAVIT
NLFGGIPFIGADVVEWIRGNYVVADSTLTRFFMLHVFLLPIAIILLIGVHFYSLRIPHVNNQEGEEIDFELEEKKFIEGK
KKESKVIPFWPVFLSKDIFVVCAFMVFFFYLVCYHYDFAMDPINFERANSLKTPPHIYPEWYFLWSYEVLRGFFFSADLG
LMAFGVAQVIFFLLPFLDRSPVVAPAHKRPAFMVWFWLVIIDMIVLTIYGKLPPLGIGKYIGLAGSITFLALFFVVLPII
TIAERKKQGGVR

Sequences:

>Translated_412_residues
MAEIKKAKNLGEWLDMRLGTNKLVKVLMTEYWIPKNINFLWAMGVILLTLFGVLVVSGIFLLMYYKPDAKMAFDSVNFTI
MQEVAYGWLWRHMHATAASMIFVIIYIHMFVAIYYGSYKKGREMIWISGMILFVVFSAEAFSGYMLPWGQMSYWAAAVIT
NLFGGIPFIGADVVEWIRGNYVVADSTLTRFFMLHVFLLPIAIILLIGVHFYSLRIPHVNNQEGEEIDFELEEKKFIEGK
KKESKVIPFWPVFLSKDIFVVCAFMVFFFYLVCYHYDFAMDPINFERANSLKTPPHIYPEWYFLWSYEVLRGFFFSADLG
LMAFGVAQVIFFLLPFLDRSPVVAPAHKRPAFMVWFWLVIIDMIVLTIYGKLPPLGIGKYIGLAGSITFLALFFVVLPII
TIAERKKQGGVR
>Mature_411_residues
AEIKKAKNLGEWLDMRLGTNKLVKVLMTEYWIPKNINFLWAMGVILLTLFGVLVVSGIFLLMYYKPDAKMAFDSVNFTIM
QEVAYGWLWRHMHATAASMIFVIIYIHMFVAIYYGSYKKGREMIWISGMILFVVFSAEAFSGYMLPWGQMSYWAAAVITN
LFGGIPFIGADVVEWIRGNYVVADSTLTRFFMLHVFLLPIAIILLIGVHFYSLRIPHVNNQEGEEIDFELEEKKFIEGKK
KESKVIPFWPVFLSKDIFVVCAFMVFFFYLVCYHYDFAMDPINFERANSLKTPPHIYPEWYFLWSYEVLRGFFFSADLGL
MAFGVAQVIFFLLPFLDRSPVVAPAHKRPAFMVWFWLVIIDMIVLTIYGKLPPLGIGKYIGLAGSITFLALFFVVLPIIT
IAERKKQGGVR

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome b family [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=390, Percent_Identity=35.8974358974359, Blast_Score=213, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6226529, Length=321, Percent_Identity=36.7601246105919, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6226532, Length=241, Percent_Identity=37.7593360995851, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6226531, Length=152, Percent_Identity=42.7631578947368, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6226530, Length=132, Percent_Identity=39.3939393939394, Blast_Score=93, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N [H]

EC number: 1.10.2.2

Molecular weight: Translated: 47608; Mature: 47477

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEIKKAKNLGEWLDMRLGTNKLVKVLMTEYWIPKNINFLWAMGVILLTLFGVLVVSGIF
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLMYYKPDAKMAFDSVNFTIMQEVAYGWLWRHMHATAASMIFVIIYIHMFVAIYYGSYKK
HHHEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GREMIWISGMILFVVFSAEAFSGYMLPWGQMSYWAAAVITNLFGGIPFIGADVVEWIRGN
CCEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
YVVADSTLTRFFMLHVFLLPIAIILLIGVHFYSLRIPHVNNQEGEEIDFELEEKKFIEGK
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEHHHHHHCCC
KKESKVIPFWPVFLSKDIFVVCAFMVFFFYLVCYHYDFAMDPINFERANSLKTPPHIYPE
CCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCC
WYFLWSYEVLRGFFFSADLGLMAFGVAQVIFFLLPFLDRSPVVAPAHKRPAFMVWFWLVI
CEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
IDMIVLTIYGKLPPLGIGKYIGLAGSITFLALFFVVLPIITIAERKKQGGVR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2821268; 3004982; 2821272; 2556259; 2176897 [H]