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The map label for this gene is nuoN

Identifier: 109946832

GI number: 109946832

Start: 180453

End: 181931

Strand: Reverse

Name: nuoN

Synonym: Hac_0211

Alternate gene names: 109946832

Gene position: 181931-180453 (Counterclockwise)

Preceding gene: 109946833

Following gene: 109946831

Centisome position: 11.71

GC content: 41.92

Gene sequence:

>1479_bases
ATGTTAATAGATAGTCTCCATATCTCTTTTGATAGCTTCAATTTTGAGAGCATTTTACCCATGCTTGTGTTGGTGTGTGG
GGGGATTTTCACGCTCTTAATCAACGCTTTCACTTCAAGATTTTCACGCAACTTGAACATGTTTTTATGCATGCTCTTTT
TGGTTTTGGATTTTTTAGTGGTTTTAGGGTTAGAGCAGCAAGAAAACGCTTTCTTCGGATTTTTGAGCCTAGACACCCTC
TCGCTAGTTTCTCAAAGCATTGTCTTAATTTCAGCCTTTTTGCTCATTTTTTTAGCCCTTTCAAAAGAGCGTTTCAACGA
ATTTCAGACCGCTGAGTTTTATCCTTTATACTTGTTTATTATCGCCGGCTTTCAGTTCATGGTTTCAAGCAATCATTTAC
TCTTAATGCTGATTGGGTTGGAGACAGCGTCCTTGCCTATTTGTGTGTTAATGGCGTTGAGCGGTAAACGCTACGGATTA
GAAGCAGGGATCAAGTATTTCACCATGGGGGCGATGGCGAGTGCGTTTTTTGCTATGGGGGCGATGGCTTTTTATTTGCT
TACAGGGAGCTTGAATCTTGAAGTCATTACCCTATATTTGTACACAGAAGGCGTCACAAACCCCATGCTCTTTGCGATGG
GCGTTATCTTTTTGATTGGAGCGATTGGCTTTAAGGTTTCTTTAGTGCCTTTTCATACTTGGATGCCTGATGTGTATGAG
GGCAATAACCCGGTTTTTGCAAGCTATATTTCCATCGTGCCTAAAATCGCTGGTTTTGTGGTAGCGACTCGCCTTTTTGG
GGCGTTTATAGACACTCGTATCGCTTGGGTAGAAGACATTTTTTACGCCCTCATTCTTATCACTATCACCATTCCTAATT
TGATCGCTTTATGGCAAGAAGATGTCAAAAGGATGCTCGCTTATAGCTCCATTTCGCATTCTGGGTTTGCTTTAGCATGC
GTGTTTATCCACACTGAAGAAAGTCAAAAAGCGATGTTTGTTTATTGGTTTATGTTTGCATTCACTTACATTGGGGCTTT
TGGTCTTTTATGGCTTTTGAAAAGCCGTGAAAAAACATGGGATGAACGCTATGATCACCCCTATTCTAAATTTGACGGTC
TTATCAAAACCCACCCTTTAGTGGCTATTTTAGGCGCTATTTTTGTTTTTGGGCTTGCAGGAATCCCGCCTTTTAGCGTG
TTTTGGGGGAAATTTTTAGCCGTCGAAAGCGCTCTAGAGAGCAACCACATTCTTTTAGCGGCGGTGATGTTAGCTAATAG
TGCGGTGGCTGTGTTTTATTATTTCCGCTGGCTTGTGGCGATGTTTTTTAATAAGCCCTTGCAAACCCAAAGCTACGCTG
AAAGCGACATTTACACCCAAAACGCCACCATGCCCATTTATGCGGTCATCATCGCTATGGCGTTAGTGTGCTTGTTCTCT
GTTTTTATGATGCGAGGGCTTTTAGAGTTTGTGGCTTAA

Upstream 100 bases:

>100_bases
AAACCGATTGAACAAGGCTCTAAACAGCTTTTAGAAGTGATAGAAACGCGCTCGCTCCCTTTTTTAGGCTCATTGGACAC
CAATATAAAAGAGGTCTCTT

Downstream 100 bases:

>100_bases
GTCAAAAATCTTTCTTTTAATGGGCGTGAGCTTGTTTGCACATTCGCTTAATGCCTTAAGCTTGACACTCACGCAAGGCA
AAGAAGAAGGGGAAGACTTT

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLIDSLHISFDSFNFESILPMLVLVCGGIFTLLINAFTSRFSRNLNMFLCMLFLVLDFLVVLGLEQQENAFFGFLSLDTL
SLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYPLYLFIIAGFQFMVSSNHLLLMLIGLETASLPICVLMALSGKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLYTEGVTNPMLFAMGVIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILITITIPNLIALWQEDVKRMLAYSSISHSGFALAC
VFIHTEESQKAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFDGLIKTHPLVAILGAIFVFGLAGIPPFSV
FWGKFLAVESALESNHILLAAVMLANSAVAVFYYFRWLVAMFFNKPLQTQSYAESDIYTQNATMPIYAVIIAMALVCLFS
VFMMRGLLEFVA

Sequences:

>Translated_492_residues
MLIDSLHISFDSFNFESILPMLVLVCGGIFTLLINAFTSRFSRNLNMFLCMLFLVLDFLVVLGLEQQENAFFGFLSLDTL
SLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYPLYLFIIAGFQFMVSSNHLLLMLIGLETASLPICVLMALSGKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLYTEGVTNPMLFAMGVIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILITITIPNLIALWQEDVKRMLAYSSISHSGFALAC
VFIHTEESQKAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFDGLIKTHPLVAILGAIFVFGLAGIPPFSV
FWGKFLAVESALESNHILLAAVMLANSAVAVFYYFRWLVAMFFNKPLQTQSYAESDIYTQNATMPIYAVIIAMALVCLFS
VFMMRGLLEFVA
>Mature_492_residues
MLIDSLHISFDSFNFESILPMLVLVCGGIFTLLINAFTSRFSRNLNMFLCMLFLVLDFLVVLGLEQQENAFFGFLSLDTL
SLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYPLYLFIIAGFQFMVSSNHLLLMLIGLETASLPICVLMALSGKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLYTEGVTNPMLFAMGVIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILITITIPNLIALWQEDVKRMLAYSSISHSGFALAC
VFIHTEESQKAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFDGLIKTHPLVAILGAIFVFGLAGIPPFSV
FWGKFLAVESALESNHILLAAVMLANSAVAVFYYFRWLVAMFFNKPLQTQSYAESDIYTQNATMPIYAVIIAMALVCLFS
VFMMRGLLEFVA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=360, Percent_Identity=33.8888888888889, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1788831, Length=376, Percent_Identity=24.2021276595745, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788614, Length=419, Percent_Identity=26.7303102625298, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_HELAH (Q17Z65)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664060.1
- STRING:   Q17Z65
- GeneID:   4176460
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0211
- NMPDR:   fig|382638.8.peg.205
- HOGENOM:   HBG747830
- OMA:   LMFFSEP
- PhylomeDB:   Q17Z65
- ProtClustDB:   PRK05777
- BioCyc:   HACI382638:HAC_0211-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 55370; Mature: 55370

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x118565b0)-; HASH(0x129a6784)-; HASH(0x12380df4)-; HASH(0x11ce8198)-; HASH(0x12998a50)-; HASH(0x129a9110)-; HASH(0x11bff4d0)-; HASH(0x129a3e84)-; HASH(0x129a8e94)-; HASH(0x129a3e0c)-; HASH(0x129a3c50)-; HASH(0x11ce812c)-; HASH(0x124f3ec8)-; HASH(0x11503824)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSLHISFDSFNFESILPMLVLVCGGIFTLLINAFTSRFSRNLNMFLCMLFLVLDFLV
CCEECEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLGLEQQENAFFGFLSLDTLSLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYPLYLFI
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IAGFQFMVSSNHLLLMLIGLETASLPICVLMALSGKRYGLEAGIKYFTMGAMASAFFAMG
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AMAFYLLTGSLNLEVITLYLYTEGVTNPMLFAMGVIFLIGAIGFKVSLVPFHTWMPDVYE
HHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCC
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILITITIPNLIALWQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKRMLAYSSISHSGFALACVFIHTEESQKAMFVYWFMFAFTYIGAFGLLWLLKSREKTW
HHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERYDHPYSKFDGLIKTHPLVAILGAIFVFGLAGIPPFSVFWGKFLAVESALESNHILLA
HHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
AVMLANSAVAVFYYFRWLVAMFFNKPLQTQSYAESDIYTQNATMPIYAVIIAMALVCLFS
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
VFMMRGLLEFVA
HHHHHHHHHHHH
>Mature Secondary Structure
MLIDSLHISFDSFNFESILPMLVLVCGGIFTLLINAFTSRFSRNLNMFLCMLFLVLDFLV
CCEECEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLGLEQQENAFFGFLSLDTLSLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYPLYLFI
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IAGFQFMVSSNHLLLMLIGLETASLPICVLMALSGKRYGLEAGIKYFTMGAMASAFFAMG
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AMAFYLLTGSLNLEVITLYLYTEGVTNPMLFAMGVIFLIGAIGFKVSLVPFHTWMPDVYE
HHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCC
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILITITIPNLIALWQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKRMLAYSSISHSGFALACVFIHTEESQKAMFVYWFMFAFTYIGAFGLLWLLKSREKTW
HHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERYDHPYSKFDGLIKTHPLVAILGAIFVFGLAGIPPFSVFWGKFLAVESALESNHILLA
HHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
AVMLANSAVAVFYYFRWLVAMFFNKPLQTQSYAESDIYTQNATMPIYAVIIAMALVCLFS
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
VFMMRGLLEFVA
HHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA