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The map label for this gene is dgoD [H]

Identifier: 110681073

GI number: 110681073

Start: 3799812

End: 3801053

Strand: Direct

Name: dgoD [H]

Synonym: RD1_3939

Alternate gene names: 110681073

Gene position: 3799812-3801053 (Clockwise)

Preceding gene: 110681072

Following gene: 110681088

Centisome position: 91.94

GC content: 62.0

Gene sequence:

>1242_bases
ATGAAGCTGAAAGACCTCGACGTGATCATCACGGCCCCACCGGCGCCCGGCTGGGGCGGGCGGTATTGGATTTTGGTAAA
GCTGACCACGGATAACGGCATCACCGGCTGGGGCGAATGCTACGCCTCAAGCGTCGGACCCGTCGCGATGCGCGCCGTGA
TCGACGATGTCTTTGCCCGCCACATGGCAGGCGAGAACCCCGAAGACATAGAACTGATGTTCCGCCGCGCCTATTCCTCC
GGTTTCACGCAGCGCCCCGATCTGACGGTCATCGGCGCGTTTTCCGGTTTGGAAATCGCCTGTTGGGACATTCTGGGCAA
GGCGCGTGAACGCCCTGTTTATGCCCTTCTGGGCGGTCGCATGAACGATCGTATCCGCGCCTACACCTATCTTTATCCGC
TGGCGCATCACGATCCGTCCGCTTTCTGGAGCTCTCCGGAAATGGCCGCTGAAACCGCCGTTGCGATGGTTGACAAAGGC
TATACCGCACTCAAATTCGACCCTGCGGGCCCCTATACGATGCGCGGCGGGCACATGCCTGCGATGCGCGATATCGCGCT
GTCCGTGGCCTTTTGCAAAGCCATCCGCGACGCTGTGGGCGACCGGGCAGACCTGCTGTTCGGCACCCATGGTCAGTTCA
GCACCGCCGGGGCGATCCGTCTGGGTCAGGCGCTGGAACCCTATAGCCCGCTGTGGTTCGAAGAGCCGATACCGCCTGAC
GCTGTTGAGGAGATGGCGAAAGTCGCGCGCGCCGTGCGTATCCCCGTGGCGACCGGCGAAAGGCTGACGACCAAGGCCGA
GTTCGCCCCCGTGCTGCGCGCGGGTGCGGCGACAATCCTGCAACCCGCATTGGGGCGCGCAGGCGGCATCTGGGAGATGA
AAAAGGTCGCTGCCATGGCGGAAGTCTATAATGCGCAAATGGCCCCGCATCTTTATGCAGGGCCGGTTGAATGGGCCGCC
AACATCCATCTGGCGGCGTCCATTCCAAACGTGCTGATGGCGGAGTGTATCGAAACGCCATTTCACGACGCGCTGATCAA
GGGTTGGATCCGCGTGGAAGACGGCTTTGTCACGCCGCCGCAGACGCCCGGTCTGGGCATCGACGTTGACGAAGAACTGG
CCCGCGCGCATCCATACACACAGGACGGGTTGCATCTGGAAATGCAAGAAGCGGCCTGTGACTACGTGAATGGCAATAGT
TTTCAGGGGGGCGCGCCCGCGCCGGATGGCAAAACGGATTGA

Upstream 100 bases:

>100_bases
GATCAGATCAACGAGGCGATTGCAGATACCAAGACAGGTGCCGCGCGACGCAATGTGATCGTGTTCGACACCTAGCGGGT
CAAGCCAAGAGGGAACAGAA

Downstream 100 bases:

>100_bases
GGGCCAGATCAGGTGCGCGCCGCCTCGAACGCGGCCCAGACATCTTCGAAATCCTCAAAGCTCAACCGCTTGCCTTTTAC
CGCGTCGAATATGATCCGCT

Product: racemase, putative

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKLKDLDVIITAPPAPGWGGRYWILVKLTTDNGITGWGECYASSVGPVAMRAVIDDVFARHMAGENPEDIELMFRRAYSS
GFTQRPDLTVIGAFSGLEIACWDILGKARERPVYALLGGRMNDRIRAYTYLYPLAHHDPSAFWSSPEMAAETAVAMVDKG
YTALKFDPAGPYTMRGGHMPAMRDIALSVAFCKAIRDAVGDRADLLFGTHGQFSTAGAIRLGQALEPYSPLWFEEPIPPD
AVEEMAKVARAVRIPVATGERLTTKAEFAPVLRAGAATILQPALGRAGGIWEMKKVAAMAEVYNAQMAPHLYAGPVEWAA
NIHLAASIPNVLMAECIETPFHDALIKGWIRVEDGFVTPPQTPGLGIDVDEELARAHPYTQDGLHLEMQEAACDYVNGNS
FQGGAPAPDGKTD

Sequences:

>Translated_413_residues
MKLKDLDVIITAPPAPGWGGRYWILVKLTTDNGITGWGECYASSVGPVAMRAVIDDVFARHMAGENPEDIELMFRRAYSS
GFTQRPDLTVIGAFSGLEIACWDILGKARERPVYALLGGRMNDRIRAYTYLYPLAHHDPSAFWSSPEMAAETAVAMVDKG
YTALKFDPAGPYTMRGGHMPAMRDIALSVAFCKAIRDAVGDRADLLFGTHGQFSTAGAIRLGQALEPYSPLWFEEPIPPD
AVEEMAKVARAVRIPVATGERLTTKAEFAPVLRAGAATILQPALGRAGGIWEMKKVAAMAEVYNAQMAPHLYAGPVEWAA
NIHLAASIPNVLMAECIETPFHDALIKGWIRVEDGFVTPPQTPGLGIDVDEELARAHPYTQDGLHLEMQEAACDYVNGNS
FQGGAPAPDGKTD
>Mature_413_residues
MKLKDLDVIITAPPAPGWGGRYWILVKLTTDNGITGWGECYASSVGPVAMRAVIDDVFARHMAGENPEDIELMFRRAYSS
GFTQRPDLTVIGAFSGLEIACWDILGKARERPVYALLGGRMNDRIRAYTYLYPLAHHDPSAFWSSPEMAAETAVAMVDKG
YTALKFDPAGPYTMRGGHMPAMRDIALSVAFCKAIRDAVGDRADLLFGTHGQFSTAGAIRLGQALEPYSPLWFEEPIPPD
AVEEMAKVARAVRIPVATGERLTTKAEFAPVLRAGAATILQPALGRAGGIWEMKKVAAMAEVYNAQMAPHLYAGPVEWAA
NIHLAASIPNVLMAECIETPFHDALIKGWIRVEDGFVTPPQTPGLGIDVDEELARAHPYTQDGLHLEMQEAACDYVNGNS
FQGGAPAPDGKTD

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=396, Percent_Identity=23.2323232323232, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI186972148, Length=311, Percent_Identity=24.1157556270096, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI48994953, Length=357, Percent_Identity=31.3725490196078, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787864, Length=403, Percent_Identity=24.5657568238213, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI226510960, Length=291, Percent_Identity=25.4295532646048, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 44743; Mature: 44743

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKDLDVIITAPPAPGWGGRYWILVKLTTDNGITGWGECYASSVGPVAMRAVIDDVFAR
CCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
HMAGENPEDIELMFRRAYSSGFTQRPDLTVIGAFSGLEIACWDILGKARERPVYALLGGR
HHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHHHHHHHHCCCEEEEECCC
MNDRIRAYTYLYPLAHHDPSAFWSSPEMAAETAVAMVDKGYTALKFDPAGPYTMRGGHMP
CCCCEEEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCC
AMRDIALSVAFCKAIRDAVGDRADLLFGTHGQFSTAGAIRLGQALEPYSPLWFEEPIPPD
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHH
AVEEMAKVARAVRIPVATGERLTTKAEFAPVLRAGAATILQPALGRAGGIWEMKKVAAMA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EVYNAQMAPHLYAGPVEWAANIHLAASIPNVLMAECIETPFHDALIKGWIRVEDGFVTPP
HHHHHHCCCCEECCCHHHHCCEEEEECCHHHHHHHHHCCCHHHHHHHCEEEEECCCCCCC
QTPGLGIDVDEELARAHPYTQDGLHLEMQEAACDYVNGNSFQGGAPAPDGKTD
CCCCCCCCCCHHHHHCCCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLKDLDVIITAPPAPGWGGRYWILVKLTTDNGITGWGECYASSVGPVAMRAVIDDVFAR
CCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
HMAGENPEDIELMFRRAYSSGFTQRPDLTVIGAFSGLEIACWDILGKARERPVYALLGGR
HHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHHHHHHHHCCCEEEEECCC
MNDRIRAYTYLYPLAHHDPSAFWSSPEMAAETAVAMVDKGYTALKFDPAGPYTMRGGHMP
CCCCEEEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCC
AMRDIALSVAFCKAIRDAVGDRADLLFGTHGQFSTAGAIRLGQALEPYSPLWFEEPIPPD
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHH
AVEEMAKVARAVRIPVATGERLTTKAEFAPVLRAGAATILQPALGRAGGIWEMKKVAAMA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EVYNAQMAPHLYAGPVEWAANIHLAASIPNVLMAECIETPFHDALIKGWIRVEDGFVTPP
HHHHHHCCCCEECCCHHHHCCEEEEECCHHHHHHHHHCCCHHHHHHHCEEEEECCCCCCC
QTPGLGIDVDEELARAHPYTQDGLHLEMQEAACDYVNGNSFQGGAPAPDGKTD
CCCCCCCCCCHHHHHCCCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA