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The map label for this gene is ribF [H]

Identifier: 110680684

GI number: 110680684

Start: 3385175

End: 3386107

Strand: Direct

Name: ribF [H]

Synonym: RD1_3523

Alternate gene names: 110680684

Gene position: 3385175-3386107 (Clockwise)

Preceding gene: 110680683

Following gene: 110680685

Centisome position: 81.9

GC content: 61.74

Gene sequence:

>933_bases
ATGAAAATACTGCGCGATTACCAATTCGTTGAACCCGAGCATCGTGGCGCCAGCGCTGCGATTGGCAATTTTGACGGCGT
CCACCTAGGGCATCAATCCGTTATCGACCTTGCGCGCAGCGTCGCGCCGGATGCCCCTTTGGGTATCCTGACGTTTGAGC
CACACCCGCGCGCGTTTTTTGCCCCCGACGCACCGCCCTTCAGGCTGATGAGCCGCGAGGCACGCGCCAGCCGGTTGGAA
AAACTCGGTGTGGATATCCTCTACGAAGTGAACTTCAACGCCGCCCTCGCCAGCCTGACCCCCGAGGACTTCGCCGTGCG
CGTCATCCACGAGGGGTTCGGGCTGAAACATGTCATCGTCGGTGCGGATTTCTGCTTTGGCAAAGGGCGCAGCGGGACGG
CTGATGACCTCAGGCGTTTCGGCCAGACCATGGGGTTTGACGTCACGGTGGCACCGCTGATGGCACGCTCCGACATCACC
GTGTCCTCAACGGCCATCCGCAGCGCGCTGAGTGCGGGCAAGCCCCGTGAGGCCGCCGAGATGCTGGGCCACTGGCACCG
GATCGAAGGGCCCGTGATCGGCGGGGAGCAACGCGGCCGCGAACTGGGCTATCCGACCGCGAACATGTCGATTGACGGTC
TGCACCCTCCGGCCTTTGGTGTTTATGCCGTGCTGGTTGACGTGCTCGACGGGGCGCATGCGGGCAGCTATCACGGCGTT
GCCTCAATGGGCGTGCGCCCCATGTTTGGCGAAAACCGCCCCAATCTGGAAACTTTCATCTTCGACTTTTCCGGCGATCT
TTACGGCACGCCCTTGTCGGTTGCATTGGTGGAACATCTGCGGCCAGAACTCAAATTCGACGGGCTGGATGCGTTGATTG
CGCAAATGGATCAGGACAGCACCGCCGCGCGCACCATTCTGGACGCTTTATGA

Upstream 100 bases:

>100_bases
CGAAGCGACCGTGATGGCGCCGTCACGCAAGTTCGACTAAGCATCACGCGCACCCCGCACGGCGCTTGCGTGTTTTCACG
CTGCGGGCTACGCAGGGCGC

Downstream 100 bases:

>100_bases
GCGACCCGATTGACCGCAAGGGCCTCAAGGACCGCTATTGGGAGCGCAAGCCGCTGTCCGCGATGAACCAGCGCGAGTGG
GAAGCACTGTGCGATGGATG

Product: riboflavin biosynthesis protein RibF

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKILRDYQFVEPEHRGASAAIGNFDGVHLGHQSVIDLARSVAPDAPLGILTFEPHPRAFFAPDAPPFRLMSREARASRLE
KLGVDILYEVNFNAALASLTPEDFAVRVIHEGFGLKHVIVGADFCFGKGRSGTADDLRRFGQTMGFDVTVAPLMARSDIT
VSSTAIRSALSAGKPREAAEMLGHWHRIEGPVIGGEQRGRELGYPTANMSIDGLHPPAFGVYAVLVDVLDGAHAGSYHGV
ASMGVRPMFGENRPNLETFIFDFSGDLYGTPLSVALVEHLRPELKFDGLDALIAQMDQDSTAARTILDAL

Sequences:

>Translated_310_residues
MKILRDYQFVEPEHRGASAAIGNFDGVHLGHQSVIDLARSVAPDAPLGILTFEPHPRAFFAPDAPPFRLMSREARASRLE
KLGVDILYEVNFNAALASLTPEDFAVRVIHEGFGLKHVIVGADFCFGKGRSGTADDLRRFGQTMGFDVTVAPLMARSDIT
VSSTAIRSALSAGKPREAAEMLGHWHRIEGPVIGGEQRGRELGYPTANMSIDGLHPPAFGVYAVLVDVLDGAHAGSYHGV
ASMGVRPMFGENRPNLETFIFDFSGDLYGTPLSVALVEHLRPELKFDGLDALIAQMDQDSTAARTILDAL
>Mature_310_residues
MKILRDYQFVEPEHRGASAAIGNFDGVHLGHQSVIDLARSVAPDAPLGILTFEPHPRAFFAPDAPPFRLMSREARASRLE
KLGVDILYEVNFNAALASLTPEDFAVRVIHEGFGLKHVIVGADFCFGKGRSGTADDLRRFGQTMGFDVTVAPLMARSDIT
VSSTAIRSALSAGKPREAAEMLGHWHRIEGPVIGGEQRGRELGYPTANMSIDGLHPPAFGVYAVLVDVLDGAHAGSYHGV
ASMGVRPMFGENRPNLETFIFDFSGDLYGTPLSVALVEHLRPELKFDGLDALIAQMDQDSTAARTILDAL

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=307, Percent_Identity=35.5048859934853, Blast_Score=174, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24644927, Length=125, Percent_Identity=35.2, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 33522; Mature: 33522

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILRDYQFVEPEHRGASAAIGNFDGVHLGHQSVIDLARSVAPDAPLGILTFEPHPRAFF
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCCCEEEEEECCCCCEEE
APDAPPFRLMSREARASRLEKLGVDILYEVNFNAALASLTPEDFAVRVIHEGFGLKHVIV
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCHHEEEEECCCCCEEEEEE
GADFCFGKGRSGTADDLRRFGQTMGFDVTVAPLMARSDITVSSTAIRSALSAGKPREAAE
ECCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHCCCCCEEHHHHHHHHHHCCCCHHHHH
MLGHWHRIEGPVIGGEQRGRELGYPTANMSIDGLHPPAFGVYAVLVDVLDGAHAGSYHGV
HHHHHHHCCCCEECCHHCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCH
ASMGVRPMFGENRPNLETFIFDFSGDLYGTPLSVALVEHLRPELKFDGLDALIAQMDQDS
HHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCH
TAARTILDAL
HHHHHHHHCC
>Mature Secondary Structure
MKILRDYQFVEPEHRGASAAIGNFDGVHLGHQSVIDLARSVAPDAPLGILTFEPHPRAFF
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCCCEEEEEECCCCCEEE
APDAPPFRLMSREARASRLEKLGVDILYEVNFNAALASLTPEDFAVRVIHEGFGLKHVIV
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCHHEEEEECCCCCEEEEEE
GADFCFGKGRSGTADDLRRFGQTMGFDVTVAPLMARSDITVSSTAIRSALSAGKPREAAE
ECCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHCCCCCEEHHHHHHHHHHCCCCHHHHH
MLGHWHRIEGPVIGGEQRGRELGYPTANMSIDGLHPPAFGVYAVLVDVLDGAHAGSYHGV
HHHHHHHCCCCEECCHHCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCH
ASMGVRPMFGENRPNLETFIFDFSGDLYGTPLSVALVEHLRPELKFDGLDALIAQMDQDS
HHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCH
TAARTILDAL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9454067; 9108293; 9384377 [H]