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The map label for this gene is trxB [H]

Identifier: 110680667

GI number: 110680667

Start: 3370054

End: 3371031

Strand: Direct

Name: trxB [H]

Synonym: RD1_3505

Alternate gene names: 110680667

Gene position: 3370054-3371031 (Clockwise)

Preceding gene: 110680665

Following gene: 110680668

Centisome position: 81.54

GC content: 60.33

Gene sequence:

>978_bases
ATGGGCGACACACGGCGCACACGCGTTCTAATCATCGGGTCCGGACCTGCCGGATATACCGCTGGCGTTTATGCCAGCCG
CGCGATGCTCGAACCCATTCTGGTGCAGGGTATTGAACCGGGCGGACAGTTGACGACAACCACCGAGGTGGAGAACTGGC
CCGGCGACAGCGAGGTTCAGGGCCCCGATCTGATGATCCGCATGCAGGATCACGCCAAGGCCATGGGCACCGAGATCATC
GGTGACATCATCACGGATCTGAACCTTGAACAACGCCCGTTCGTGGCCAAGGGCGACAGCGGCACCACCTATATCGCCGA
CGCGGTCATTCTGGCCACCGGCGCGCGGGCCAAATGGCTGGGCCTGCCGTCAGAGGAAAAATTCAAAGGCTTCGGCGTGT
CCGCCTGTGCCACCTGTGACGGGTTTTTCTACCGGGGGCAGGAGATTGCGGTGATCGGCGGGGGCAATACCGCCGTCGAA
GAGGCGTTGTTCCTGACAAATTTCGCCTCCAAGGTGACGCTGGTGCACCGCCGTGATGAGTTACGGGCGGAAAAGATCCT
GATCGACCGGCTGATGAAAAACCCCAAGATCGAACCCCTGTGGTTCCACGAACTGGATGAGGTCGTCGGTACGGAAAACC
CGCTCGGCGTCGAAGCGATCCGCGTAAGGCACACCAAAACCTCAGAAATCACCGAAATCCCGGCGAAAGGTGTCTTCGTG
GCCATCGGTCATGCCCCGGCCAATGAACTGGTCAAGGACGTGCTCGAAACCCATATGGGCGGCTATGTGGTGACCAAGCC
GGACAGCACCGAAACCTCCATTCCCGGAGTCTTTGCGGCGGGTGATTTGACGGATCATATTTACCGTCAGGCTGTGACCT
CTGCGGGCATGGGATGTATGGCCGCCCTTGAGGCCGAAAAGTTTCTCGCCGCACAGGATGCCGAAGCGCAGGCCGACGAG
GGCGTCGCCGCCGAATAA

Upstream 100 bases:

>100_bases
TCCCCGTCACTGCGCAGGATCACGGCAGATGAGGGGTTTAAGAGCGCCTGATGCATCTATATATCCAAACGCGCTGCAAT
CAGTGAGATCGGGGATTCTT

Downstream 100 bases:

>100_bases
CTCTGGCACTGCTTGAAAGCAAACGCAGCACCCCTGCCGGGTGTTGCGTGCGTACGGTGGGTTAAGGGCACGCTCACCCG
CCTTATGGATAACGCTGGAT

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGDTRRTRVLIIGSGPAGYTAGVYASRAMLEPILVQGIEPGGQLTTTTEVENWPGDSEVQGPDLMIRMQDHAKAMGTEII
GDIITDLNLEQRPFVAKGDSGTTYIADAVILATGARAKWLGLPSEEKFKGFGVSACATCDGFFYRGQEIAVIGGGNTAVE
EALFLTNFASKVTLVHRRDELRAEKILIDRLMKNPKIEPLWFHELDEVVGTENPLGVEAIRVRHTKTSEITEIPAKGVFV
AIGHAPANELVKDVLETHMGGYVVTKPDSTETSIPGVFAAGDLTDHIYRQAVTSAGMGCMAALEAEKFLAAQDAEAQADE
GVAAE

Sequences:

>Translated_325_residues
MGDTRRTRVLIIGSGPAGYTAGVYASRAMLEPILVQGIEPGGQLTTTTEVENWPGDSEVQGPDLMIRMQDHAKAMGTEII
GDIITDLNLEQRPFVAKGDSGTTYIADAVILATGARAKWLGLPSEEKFKGFGVSACATCDGFFYRGQEIAVIGGGNTAVE
EALFLTNFASKVTLVHRRDELRAEKILIDRLMKNPKIEPLWFHELDEVVGTENPLGVEAIRVRHTKTSEITEIPAKGVFV
AIGHAPANELVKDVLETHMGGYVVTKPDSTETSIPGVFAAGDLTDHIYRQAVTSAGMGCMAALEAEKFLAAQDAEAQADE
GVAAE
>Mature_324_residues
GDTRRTRVLIIGSGPAGYTAGVYASRAMLEPILVQGIEPGGQLTTTTEVENWPGDSEVQGPDLMIRMQDHAKAMGTEIIG
DIITDLNLEQRPFVAKGDSGTTYIADAVILATGARAKWLGLPSEEKFKGFGVSACATCDGFFYRGQEIAVIGGGNTAVEE
ALFLTNFASKVTLVHRRDELRAEKILIDRLMKNPKIEPLWFHELDEVVGTENPLGVEAIRVRHTKTSEITEIPAKGVFVA
IGHAPANELVKDVLETHMGGYVVTKPDSTETSIPGVFAAGDLTDHIYRQAVTSAGMGCMAALEAEKFLAAQDAEAQADEG
VAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=58.1761006289308, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=30.8196721311475, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=47.0031545741325, Blast_Score=273, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=45.1104100946372, Blast_Score=261, Evalue=1e-70,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34801; Mature: 34670

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTRRTRVLIIGSGPAGYTAGVYASRAMLEPILVQGIEPGGQLTTTTEVENWPGDSEVQ
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
GPDLMIRMQDHAKAMGTEIIGDIITDLNLEQRPFVAKGDSGTTYIADAVILATGARAKWL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHEEEEEEECCCCEEEE
GLPSEEKFKGFGVSACATCDGFFYRGQEIAVIGGGNTAVEEALFLTNFASKVTLVHRRDE
CCCCHHHHCCCCCHHHHHCCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEECHHH
LRAEKILIDRLMKNPKIEPLWFHELDEVVGTENPLGVEAIRVRHTKTSEITEIPAKGVFV
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCEEE
AIGHAPANELVKDVLETHMGGYVVTKPDSTETSIPGVFAAGDLTDHIYRQAVTSAGMGCM
EECCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCHHH
AALEAEKFLAAQDAEAQADEGVAAE
HHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GDTRRTRVLIIGSGPAGYTAGVYASRAMLEPILVQGIEPGGQLTTTTEVENWPGDSEVQ
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
GPDLMIRMQDHAKAMGTEIIGDIITDLNLEQRPFVAKGDSGTTYIADAVILATGARAKWL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHEEEEEEECCCCEEEE
GLPSEEKFKGFGVSACATCDGFFYRGQEIAVIGGGNTAVEEALFLTNFASKVTLVHRRDE
CCCCHHHHCCCCCHHHHHCCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEECHHH
LRAEKILIDRLMKNPKIEPLWFHELDEVVGTENPLGVEAIRVRHTKTSEITEIPAKGVFV
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCEEE
AIGHAPANELVKDVLETHMGGYVVTKPDSTETSIPGVFAAGDLTDHIYRQAVTSAGMGCM
EECCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCHHH
AALEAEKFLAAQDAEAQADEGVAAE
HHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA