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The map label for this gene is ywlC [H]

Identifier: 110680589

GI number: 110680589

Start: 3282668

End: 3283612

Strand: Direct

Name: ywlC [H]

Synonym: RD1_3418

Alternate gene names: 110680589

Gene position: 3282668-3283612 (Clockwise)

Preceding gene: 110680583

Following gene: 110680591

Centisome position: 79.42

GC content: 65.61

Gene sequence:

>945_bases
ATGAAGACGACAGAGCCAACATGTCTGACGCCAACGCCGGATGGTATCGCGCAAGCAGCCGATCTGTTGCGCACCGGCGC
GCTGGTCGCCTTTCCAACGGAAACGGTGTACGGCCTTGGCGCGGATGCGCGCAACGGGCGCGCTGTCGCCACTGTTTTCG
AAGCCAAGGGCAGGCCAAGTTTCAACCCGCTGATCGTGCATGTGCATGACGCAACGCAGGCCCGGCGGTTCTGCCACTGG
TCTGACAGCGCCGAGAAACTGGCCACGGCCTTCTGGCCCGGCCCGGTGAGCCTTGTGCTGCCGCTGCGTGAGGAGCACGG
TCTGTCCTCCCTCGTGACTGCCGGGCTGCCCACGGTTGCTCTGCGGGTGCCCGCGCATCCCGCCGCGCGCGCCTTGTTGC
GGGCCTTTGACGGCCCTGTTGCCGCGCCCTCTGCGAACCCGTCTGGGAAAATCAGTCCCACGACCGCGCGGCATGTGGCC
GAAGGTCTGGGCACCAAGGTAGCGGCAATTCTGGATGACGGGCCTTGCAGCGTGGGGCTGGAAAGCACCATCGTCGGTCT
TGATGCCGCCCCCTGTTTGCTGCGACCCGGCGGATTGCCCGCCGAAGAGATCGAGCGTGTGCTGGGGCAAACGCTGTCCC
GTGCGACCGAGGGCAAGATATCTGCACCCGGACAACTGGTGTCTCACTACGCACCCGACGGGCACGTTCGCCTGAATGCA
ACAAGCGCGCAGGCGGGCGAGGTTTTGCTGGGATTTGGTCACATGGACTGCGATCTCAACCTGTCCCGCGACGGGGATCT
GACCGAAGCGGCCAGCGCTCTTTTTGAGAGCCTGCACCAGTTGGACGCCACGGGAAAGGCCATTGCCGTGGCCCCGATCC
CGCAGCATGGGCTTGGTGCCGCCATCAATGACCGTTTACGCCGCGCGGCGGCTCCGCGCCCTTGA

Upstream 100 bases:

>100_bases
ACTGCTGCCTTGGCAAGAGGCAGCACAGCTTATAAAGCGTCGCTACAGCATGGGCCGCCCGGTCCGGCACAGCAATAGAA
ACGCGGCGTCACAGGATTTG

Downstream 100 bases:

>100_bases
CCCCAGAGTTCAGGCGTGCCCTGCCGCCGGGCTCAGGTTGATGGGATCGACCCCAAGGCTGTGCAATGCCTCGGACCATT
TGCGCGCCGCAGGCAGATCG

Product: Sua5/YciO/YrdC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKTTEPTCLTPTPDGIAQAADLLRTGALVAFPTETVYGLGADARNGRAVATVFEAKGRPSFNPLIVHVHDATQARRFCHW
SDSAEKLATAFWPGPVSLVLPLREEHGLSSLVTAGLPTVALRVPAHPAARALLRAFDGPVAAPSANPSGKISPTTARHVA
EGLGTKVAAILDDGPCSVGLESTIVGLDAAPCLLRPGGLPAEEIERVLGQTLSRATEGKISAPGQLVSHYAPDGHVRLNA
TSAQAGEVLLGFGHMDCDLNLSRDGDLTEAASALFESLHQLDATGKAIAVAPIPQHGLGAAINDRLRRAAAPRP

Sequences:

>Translated_314_residues
MKTTEPTCLTPTPDGIAQAADLLRTGALVAFPTETVYGLGADARNGRAVATVFEAKGRPSFNPLIVHVHDATQARRFCHW
SDSAEKLATAFWPGPVSLVLPLREEHGLSSLVTAGLPTVALRVPAHPAARALLRAFDGPVAAPSANPSGKISPTTARHVA
EGLGTKVAAILDDGPCSVGLESTIVGLDAAPCLLRPGGLPAEEIERVLGQTLSRATEGKISAPGQLVSHYAPDGHVRLNA
TSAQAGEVLLGFGHMDCDLNLSRDGDLTEAASALFESLHQLDATGKAIAVAPIPQHGLGAAINDRLRRAAAPRP
>Mature_314_residues
MKTTEPTCLTPTPDGIAQAADLLRTGALVAFPTETVYGLGADARNGRAVATVFEAKGRPSFNPLIVHVHDATQARRFCHW
SDSAEKLATAFWPGPVSLVLPLREEHGLSSLVTAGLPTVALRVPAHPAARALLRAFDGPVAAPSANPSGKISPTTARHVA
EGLGTKVAAILDDGPCSVGLESTIVGLDAAPCLLRPGGLPAEEIERVLGQTLSRATEGKISAPGQLVSHYAPDGHVRLNA
TSAQAGEVLLGFGHMDCDLNLSRDGDLTEAASALFESLHQLDATGKAIAVAPIPQHGLGAAINDRLRRAAAPRP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=183, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI2367210, Length=139, Percent_Identity=33.0935251798561, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=380, Percent_Identity=36.3157894736842, Blast_Score=188, Evalue=9e-49,
Organism=Drosophila melanogaster, GI78707274, Length=189, Percent_Identity=29.1005291005291, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 32487; Mature: 32487

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTEPTCLTPTPDGIAQAADLLRTGALVAFPTETVYGLGADARNGRAVATVFEAKGRPS
CCCCCCCEECCCCHHHHHHHHHHHHCCEEEECCCHHEECCCCCCCCCEEEEEEECCCCCC
FNPLIVHVHDATQARRFCHWSDSAEKLATAFWPGPVSLVLPLREEHGLSSLVTAGLPTVA
CCCEEEEEECCHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECHHHCCHHHHHHCCCCEEE
LRVPAHPAARALLRAFDGPVAAPSANPSGKISPTTARHVAEGLGTKVAAILDDGPCSVGL
EECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
ESTIVGLDAAPCLLRPGGLPAEEIERVLGQTLSRATEGKISAPGQLVSHYAPDGHVRLNA
CCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEE
TSAQAGEVLLGFGHMDCDLNLSRDGDLTEAASALFESLHQLDATGKAIAVAPIPQHGLGA
CCCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
AINDRLRRAAAPRP
HHHHHHHHHCCCCC
>Mature Secondary Structure
MKTTEPTCLTPTPDGIAQAADLLRTGALVAFPTETVYGLGADARNGRAVATVFEAKGRPS
CCCCCCCEECCCCHHHHHHHHHHHHCCEEEECCCHHEECCCCCCCCCEEEEEEECCCCCC
FNPLIVHVHDATQARRFCHWSDSAEKLATAFWPGPVSLVLPLREEHGLSSLVTAGLPTVA
CCCEEEEEECCHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECHHHCCHHHHHHCCCCEEE
LRVPAHPAARALLRAFDGPVAAPSANPSGKISPTTARHVAEGLGTKVAAILDDGPCSVGL
EECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
ESTIVGLDAAPCLLRPGGLPAEEIERVLGQTLSRATEGKISAPGQLVSHYAPDGHVRLNA
CCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEE
TSAQAGEVLLGFGHMDCDLNLSRDGDLTEAASALFESLHQLDATGKAIAVAPIPQHGLGA
CCCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
AINDRLRRAAAPRP
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]