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The map label for this gene is kdtA [H]

Identifier: 110680488

GI number: 110680488

Start: 3170007

End: 3171302

Strand: Direct

Name: kdtA [H]

Synonym: RD1_3308

Alternate gene names: 110680488

Gene position: 3170007-3171302 (Clockwise)

Preceding gene: 110680487

Following gene: 110680489

Centisome position: 76.7

GC content: 61.11

Gene sequence:

>1296_bases
ATGCGCCCCCCTTTGCTCTACCATCTCTATGTCGGTGCAACGGCGCTGCTCGTCCCGTTCTTTGCCTGGATTGAAACCCG
GAAATTGCGCGCCGCAGGCGTATCAATCCTGCGCGCGCATGAAAAACTGGGCCATGCCACGGCCACCCGCGCAGGCGCCG
GCCCGCTGATCTGGTTCCATGCAGCCTCGGTTGGCGAAAGCATGTCGGTCCTGTCACTGATCGGTGAAATGGGGCGGCAG
ATGCCGCGCGCCCATTTTCTGATCACCTCTGGCACGGCCACATCGGCCAAGATGGTGGCAAACCACCTGCCCCCGCGCAC
GGTGCACCAGTTTGCCCCCCTTGATGCGCCCGGTCCGGTGCGTCGGTTCATCCGGCACTGGCGTCCGGAGTGTGTGGTTT
TCGTGGAAAGCGAGCTGTGGCCTCAAATGCTGCGCCTGACGCGGGACAGCGGCGCAAAGATGATCCTTGTGAACGCCCGC
CTGAGTGCGACCTCGCAAAAGGCATGGCAGCGGCGGCCCAAAACGGCGGCCTTCGTGCTGGGCACGTTCGATCTGATCCT
GACCCAGAACGACGAGATGGCGCAGGCGATGGTGGATATGCACGCCCCTGCCGATCGGGTGGCGCGTGGCATCAACCTCA
AATCACTGGCGGCCCCCTTGCAGCAAAACCCTGAAACGCTTGCAAAAATTCGCACCAGCCTGAAAGGCAGGCGTGTGTGG
GTCGCGGCCTCAACCCACAAGGGCGAAGAGGAAATCGTGTTGCGCGCGCATGTCCGGCTTTTGGCAGATAATCCGGATCT
TCTGTTGCTCCTGGCACCGCGCCACCCCGAGCGCAGCAAGGAGGTCGTGCAATTGATCGAGGAAGAGGGGTTGAGTTTCC
GTGTGCGCTCGCAGGATGAGTTACCGGGCAACCGCAACGTCTATCTTGCCGATACTTTGGGCGAGTTGGGCAATTGGTAT
GCTCTGTCCAACGCCATTTTCCTTGGTGGGTCGCTGAAACCTATTGGCGGGCATAACCCGTTTGAGGTCACGCTGAGCGG
GTCGGGTGTCATCTCCGGTCCGGAGGTTTTCAATTTCAGCGAAACATATGCCGAGATGACCCAAGCCGGTGTCGTGCAAT
TCGTCAAGGATGATGCGGAACTGGCCCAAGCGGTTGACAAGATGCTCAACGACACCGCGGTGATGGAAGCGACGGGCCGG
GCCGCGCGCGATTATGTGCGCGGCAAGTCATCCCAGACCAGCACGATTGCCACGCGGCTGATCCGTGCGCTGGATTTGCA
AGGTGAGGTCCGCTGA

Upstream 100 bases:

>100_bases
TCGCACGCAAGCCCAAGGGCCATGACTTTGACTACTCGCGCCAGCGCCTTGACGGTCAGATGCCGCGCCACATGAGCCAT
ACGGGCGGCTGACCTGCGCC

Downstream 100 bases:

>100_bases
TGTCCCCTGCCCAGATCCCCGCCCTTCGAGAGATCGAGGTGATTGCGCCCAATTTCAAACGGCGGCATTCCGGCGTCACA
TCGACCGTCATCCGTCTTGT

Product: 3-deoxy-D-manno-octulosonic acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MRPPLLYHLYVGATALLVPFFAWIETRKLRAAGVSILRAHEKLGHATATRAGAGPLIWFHAASVGESMSVLSLIGEMGRQ
MPRAHFLITSGTATSAKMVANHLPPRTVHQFAPLDAPGPVRRFIRHWRPECVVFVESELWPQMLRLTRDSGAKMILVNAR
LSATSQKAWQRRPKTAAFVLGTFDLILTQNDEMAQAMVDMHAPADRVARGINLKSLAAPLQQNPETLAKIRTSLKGRRVW
VAASTHKGEEEIVLRAHVRLLADNPDLLLLLAPRHPERSKEVVQLIEEEGLSFRVRSQDELPGNRNVYLADTLGELGNWY
ALSNAIFLGGSLKPIGGHNPFEVTLSGSGVISGPEVFNFSETYAEMTQAGVVQFVKDDAELAQAVDKMLNDTAVMEATGR
AARDYVRGKSSQTSTIATRLIRALDLQGEVR

Sequences:

>Translated_431_residues
MRPPLLYHLYVGATALLVPFFAWIETRKLRAAGVSILRAHEKLGHATATRAGAGPLIWFHAASVGESMSVLSLIGEMGRQ
MPRAHFLITSGTATSAKMVANHLPPRTVHQFAPLDAPGPVRRFIRHWRPECVVFVESELWPQMLRLTRDSGAKMILVNAR
LSATSQKAWQRRPKTAAFVLGTFDLILTQNDEMAQAMVDMHAPADRVARGINLKSLAAPLQQNPETLAKIRTSLKGRRVW
VAASTHKGEEEIVLRAHVRLLADNPDLLLLLAPRHPERSKEVVQLIEEEGLSFRVRSQDELPGNRNVYLADTLGELGNWY
ALSNAIFLGGSLKPIGGHNPFEVTLSGSGVISGPEVFNFSETYAEMTQAGVVQFVKDDAELAQAVDKMLNDTAVMEATGR
AARDYVRGKSSQTSTIATRLIRALDLQGEVR
>Mature_431_residues
MRPPLLYHLYVGATALLVPFFAWIETRKLRAAGVSILRAHEKLGHATATRAGAGPLIWFHAASVGESMSVLSLIGEMGRQ
MPRAHFLITSGTATSAKMVANHLPPRTVHQFAPLDAPGPVRRFIRHWRPECVVFVESELWPQMLRLTRDSGAKMILVNAR
LSATSQKAWQRRPKTAAFVLGTFDLILTQNDEMAQAMVDMHAPADRVARGINLKSLAAPLQQNPETLAKIRTSLKGRRVW
VAASTHKGEEEIVLRAHVRLLADNPDLLLLLAPRHPERSKEVVQLIEEEGLSFRVRSQDELPGNRNVYLADTLGELGNWY
ALSNAIFLGGSLKPIGGHNPFEVTLSGSGVISGPEVFNFSETYAEMTQAGVVQFVKDDAELAQAVDKMLNDTAVMEATGR
AARDYVRGKSSQTSTIATRLIRALDLQGEVR

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RPE1 insert domain [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=348, Percent_Identity=33.6206896551724, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 47436; Mature: 47436

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPLLYHLYVGATALLVPFFAWIETRKLRAAGVSILRAHEKLGHATATRAGAGPLIWFH
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
AASVGESMSVLSLIGEMGRQMPRAHFLITSGTATSAKMVANHLPPRTVHQFAPLDAPGPV
EHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHCCCCCCCHHH
RRFIRHWRPECVVFVESELWPQMLRLTRDSGAKMILVNARLSATSQKAWQRRPKTAAFVL
HHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEE
GTFDLILTQNDEMAQAMVDMHAPADRVARGINLKSLAAPLQQNPETLAKIRTSLKGRRVW
EEEEEEEECCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEE
VAASTHKGEEEIVLRAHVRLLADNPDLLLLLAPRHPERSKEVVQLIEEEGLSFRVRSQDE
EEECCCCCCHHEEEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCC
LPGNRNVYLADTLGELGNWYALSNAIFLGGSLKPIGGHNPFEVTLSGSGVISGPEVFNFS
CCCCCCEEEEECHHHHCCEEEECCEEEECCCCCCCCCCCCEEEEEECCCEECCCCCCCCH
ETYAEMTQAGVVQFVKDDAELAQAVDKMLNDTAVMEATGRAARDYVRGKSSQTSTIATRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCCCCCHHHHHHHH
IRALDLQGEVR
HHHHCCCCCCC
>Mature Secondary Structure
MRPPLLYHLYVGATALLVPFFAWIETRKLRAAGVSILRAHEKLGHATATRAGAGPLIWFH
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
AASVGESMSVLSLIGEMGRQMPRAHFLITSGTATSAKMVANHLPPRTVHQFAPLDAPGPV
EHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHCCCCCCCHHH
RRFIRHWRPECVVFVESELWPQMLRLTRDSGAKMILVNARLSATSQKAWQRRPKTAAFVL
HHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEE
GTFDLILTQNDEMAQAMVDMHAPADRVARGINLKSLAAPLQQNPETLAKIRTSLKGRRVW
EEEEEEEECCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEE
VAASTHKGEEEIVLRAHVRLLADNPDLLLLLAPRHPERSKEVVQLIEEEGLSFRVRSQDE
EEECCCCCCHHEEEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCC
LPGNRNVYLADTLGELGNWYALSNAIFLGGSLKPIGGHNPFEVTLSGSGVISGPEVFNFS
CCCCCCEEEEECHHHHCCEEEECCEEEECCCCCCCCCCCCEEEEEECCCEECCCCCCCCH
ETYAEMTQAGVVQFVKDDAELAQAVDKMLNDTAVMEATGRAARDYVRGKSSQTSTIATRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCCCCCHHHHHHHH
IRALDLQGEVR
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA